Type |
Details |
Score |
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
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•
•
•
•
•
|
Allele |
Name: |
synaptophysin; targeted mutation 1, Thomas C Sudhof |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
synaptophysin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
593
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
597
|
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee CH |
Year: |
1994 |
Journal: |
Structure |
Title: |
Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase. |
Volume: |
2 |
Issue: |
5 |
Pages: |
423-38 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules. |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6416298 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1844126 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6416326 |
Age: |
embryonic day 18.5 |
|
Note: |
Expressed as postsynaptic aggregates. Significantly fewer synapse number (coexpressed Syp and Chrnb2/b4). |
Specimen Label: |
2a AGD-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6416298 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-05-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1844126 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6416327 |
Age: |
embryonic day 18.5 |
|
Note: |
Expressed as postsynaptic aggregates. Significantly fewer synapse number (coexpressed Syp and Chrnb2/b4). |
Specimen Label: |
2a AGD-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tauchi T |
Year: |
1996 |
Journal: |
Blood |
Title: |
Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation, and promotes mitogenesis. |
Volume: |
87 |
Issue: |
11 |
Pages: |
4495-501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka S |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules. |
Volume: |
271 |
Issue: |
24 |
Pages: |
14610-6 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng GS |
Year: |
1993 |
Journal: |
Science |
Title: |
SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. |
Volume: |
259 |
Issue: |
5101 |
Pages: |
1607-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tamemoto H |
Year: |
1994 |
Journal: |
Nature |
Title: |
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. |
Volume: |
372 |
Issue: |
6502 |
Pages: |
182-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shiratori T |
Year: |
1997 |
Journal: |
Immunity |
Title: |
Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. |
Volume: |
6 |
Issue: |
5 |
Pages: |
583-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oriente F |
Year: |
2011 |
Journal: |
Diabetes |
Title: |
Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase. |
Volume: |
60 |
Issue: |
1 |
Pages: |
138-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tripathi MK |
Year: |
2024 |
Journal: |
Sci Rep |
Title: |
Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain. |
Volume: |
14 |
Issue: |
1 |
Pages: |
10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng CY |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Detection and organ-specific ablation of neuroendocrine cells by synaptophysin locus-based BAC cassette in transgenic mice. |
Volume: |
8 |
Issue: |
4 |
Pages: |
e60905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arrandale JM |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Insulin signaling in mice expressing reduced levels of Syp. |
Volume: |
271 |
Issue: |
35 |
Pages: |
21353-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Somvanshi RK |
Year: |
2018 |
Journal: |
Biochim Biophys Acta |
Title: |
Characterization of somatostatin receptors and associated signaling pathways in pancreas of R6/2 transgenic mice. |
Volume: |
1864 |
Issue: |
2 |
Pages: |
359-373 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feng GS |
Year: |
1994 |
Journal: |
Oncogene |
Title: |
Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp. |
Volume: |
9 |
Issue: |
6 |
Pages: |
1545-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao J |
Year: |
2018 |
Journal: |
Brain Res Bull |
Title: |
Deletion of asparagine endopeptidase reduces anxiety- and depressive-like behaviors and improves abilities of spatial cognition in mice. |
Volume: |
142 |
|
Pages: |
147-155 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vanaveski T |
Year: |
2017 |
Journal: |
Front Neurosci |
Title: |
Promoter-Specific Expression and Genomic Structure of IgLON Family Genes in Mouse. |
Volume: |
11 |
|
Pages: |
38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lehr S |
Year: |
1999 |
Journal: |
Biochemistry |
Title: |
Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro. |
Volume: |
38 |
Issue: |
1 |
Pages: |
151-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han L |
Year: |
2018 |
Journal: |
J Neuroinflammation |
Title: |
ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior. |
Volume: |
15 |
Issue: |
1 |
Pages: |
246 |
|
•
•
•
•
•
|