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Search results 601 to 700 out of 761 for Ghr

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Type Details Score
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26619308 | J:304715
First Author: Varedi M
Year: 2017
Journal: Clin Respir J
Title: Differential modulation of claudin 4 expression and myosin light chain phosphorylation by thyroid function in lung injury.
Volume: 11
Issue: 6
Pages: 797-804
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Protein
P16882
Organism: Mus musculus/domesticus
Length: 650  
Fragment?: false
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Protein Coding Gene
MGI:1930008 | Ghrl
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Ghr<tm1Jjk> | MGI:2388126
Name: growth hormone receptor; targeted mutation 1, John J Kopchick
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Ghr<tm1Arge> | MGI:2681515
Name: growth hormone receptor; targeted mutation 1, Argiris Efstratiadis
Allele Type: Targeted
Attribute String: Null/knockout
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HT Experiment
E-GEOD-988 | Transcription profiling of mouse livers from growth hormone receptor (GHR) deficient mice and mice expressing different forms of truncated GHR to study the GHR signaling domains and their associated transcripts
Series Id: GSE988
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Ghr/Ghr
Background: involves: 129S/SvEv * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ghr/Ghr
Background: involves: 129P2/OlaHsd * BALB/c
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:9521 | Laron syndrome
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Allele
Ghr<em1Smoc> | MGI:7289868
Name: growth hormone receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
17321774 | J:136762
First Author: González L
Year: 2007
Journal: Growth Horm IGF Res
Title: Differential regulation of membrane associated-growth hormone binding protein (MA-GHBP) and growth hormone receptor (GHR) expression by growth hormone (GH) in mouse liver.
Volume: 17
Issue: 2
Pages: 104-12
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Publication
7486254 | J:29435
First Author: Moody DE
Year: 1995
Journal: Anim Genet
Title: Assignment of the growth hormone receptor gene to bovine chromosome 20 using linkage analysis and somatic cell mapping.
Volume: 26
Issue: 5
Pages: 341-3
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Publication
11286784 | -
First Author: Okada S
Year: 2001
Journal: Trends Mol Med
Title: Biological effects of growth hormone and its antagonist.
Volume: 7
Issue: 3
Pages: 126-32
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Publication
14519102 | -
First Author: Schantl JA
Year: 2004
Journal: Biochem J
Title: The growth hormone receptor interacts with its sheddase, the tumour necrosis factor-alpha-converting enzyme (TACE).
Volume: 377
Issue: Pt 2
Pages: 379-84
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Protein Domain
IPR025871 | GHBP
Type: Domain
Description: Growth hormone receptor binding protein is produced either by proteolysis of the growth hormone receptor (GHR) at the cell surface thereby releasing its extracellular domain, the GHBP (growth hormone-binding protein), or, in rodents, by alternative processing of the GHR transcript. The sheddase proteolytic enzyme responsible for the cleavage is TACE (tumour necrosis factor-alpha-converting enzyme) [, ].Growth hormone (GH) binding to GH receptor is the initial step that leads to the physiological functions of the hormone []. The biological effects of GHBP are determined by the serum levels of GH, which can vary. Low levels of GH can result in a dwarf phenotype and have been positively correlated with an increased life expectancy. High levels of GH can lead to gigantism or a clinical syndrome termed acromegaly and have been implicated in diabetic eye and kidney damage [].
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Allele
Tg(Pgk1-flpo)10Sykr | MGI:4415609
Name: transgene insertion 10, Shoshana Yakar
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:4455294 | B6.Cg-Tg(Pgk1-flpo)10Sykr/J
Attribute String: transgenic, mutant strain, congenic
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Strain
MGI:4418120 | C57BL/6-Tg(Pgk1-flpo)10Sykr
Attribute String: transgenic, mutant strain, coisogenic
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Publication
19956655 | J:154848
First Author: Wu Y
Year: 2009
Journal: PLoS One
Title: High-efficient FLPo deleter mice in C57BL/6J background.
Volume: 4
Issue: 11
Pages: e8054
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Genotype
Genotype
Symbol: Tg(Pgk1-flpo)10Sykr/?
Background: involves: C3H * C57BL/6 * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Publication
28348378 | J:244431
 
First Author: Bluett RJ
Year: 2017
Journal: Nat Commun
Title: Endocannabinoid signalling modulates susceptibility to traumatic stress exposure.
Volume: 8
Pages: 14782
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Publication
25717362 | J:217933
 
First Author: McCoy E
Year: 2014
Journal: F1000Res
Title: Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord.
Volume: 3
Pages: 163
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Publication
29698489 | J:261975
First Author: De Pace R
Year: 2018
Journal: PLoS Genet
Title: Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome.
Volume: 14
Issue: 4
Pages: e1007363
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Publication
31217192 | J:282560
First Author: Sin JH
Year: 2019
Journal: J Exp Med
Title: The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses.
Volume: 216
Issue: 9
Pages: 2024-2037
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Publication
11437472 | J:127758
First Author: González L
Year: 2001
Journal: Growth Horm IGF Res
Title: Growth hormone (GH) and estradiol regulation of membrane-associated GH binding protein and GH receptors in GH releasing hormone transgenic mice.
Volume: 11
Issue: 1
Pages: 34-40
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Publication
17921143 | J:128990
First Author: Pilecka I
Year: 2007
Journal: J Biol Chem
Title: Protein-tyrosine phosphatase H1 controls growth hormone receptor signaling and systemic growth.
Volume: 282
Issue: 48
Pages: 35405-15
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Publication
10502458 | J:156077
First Author: Hellgren G
Year: 1999
Journal: Growth Horm IGF Res
Title: The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver.
Volume: 9
Issue: 3
Pages: 212-8
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Publication
24739975 | J:207677
First Author: Lee H
Year: 2014
Journal: Nature
Title: Scalable control of mounting and attack by Esr1+ neurons in the ventromedial hypothalamus.
Volume: 509
Issue: 7502
Pages: 627-32
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Publication
28348104 | J:250144
First Author: Miller MR
Year: 2017
Journal: J Cell Sci
Title: Non-canonical activity of the podosomal formin FMNL1γ supports immune cell migration.
Volume: 130
Issue: 10
Pages: 1730-1739
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Publication
26235626 | J:232894
First Author: Hrycaj SM
Year: 2015
Journal: Cell Rep
Title: Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development.
Volume: 12
Issue: 6
Pages: 903-12
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Publication
27545674 | J:240522
First Author: Muona M
Year: 2016
Journal: Am J Hum Genet
Title: Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy.
Volume: 99
Issue: 3
Pages: 683-694
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Publication
28481361 | J:314183
 
First Author: van Wijk SJL
Year: 2017
Journal: Nat Microbiol
Title: Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation.
Volume: 2
Pages: 17066
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Publication
25122120 | J:223786
First Author: Menon MB
Year: 2014
Journal: PLoS Genet
Title: Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis.
Volume: 10
Issue: 8
Pages: e1004558
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Publication
26376866 | J:226849
First Author: Ruiz M
Year: 2015
Journal: Hum Mol Genet
Title: Abnormalities of motor function, transcription and cerebellar structure in mouse models of THAP1 dystonia.
Volume: 24
Issue: 25
Pages: 7159-70
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Publication
30352124 | J:284754
First Author: Qi H
Year: 2019
Journal: J Bone Miner Res
Title: Inactivation of Nell-1 in Chondrocytes Significantly Impedes Appendicular Skeletogenesis.
Volume: 34
Issue: 3
Pages: 533-546
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Publication
33217339 | J:324731
First Author: Fricker LD
Year: 2021
Journal: Cell Chem Biol
Title: Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary.
Volume: 28
Issue: 1
Pages: 105-112.e4
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Publication
27402760 | J:234905
First Author: Whiting JL
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption.
Volume: 113
Issue: 30
Pages: E4328-37
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Publication
24164893 | J:206750
First Author: Whiteman EL
Year: 2014
Journal: Mol Cell Biol
Title: Crumbs3 is essential for proper epithelial development and viability.
Volume: 34
Issue: 1
Pages: 43-56
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Publication
33177085 | J:331852
 
First Author: Kiss B
Year: 2020
Journal: Sci Adv
Title: Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle.
Volume: 6
Issue: 46
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Publication
29891904 | J:278009
First Author: López Tobón A
Year: 2018
Journal: Sci Rep
Title: The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10.
Volume: 8
Issue: 1
Pages: 8811
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Publication
28104585 | J:241953
First Author: Miller C
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: RCAD/BiP pathway is necessary for the proper synthesis of digestive enzymes and secretory function of the exocrine pancreas.
Volume: 312
Issue: 3
Pages: G314-G326
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Publication
27646003 | J:237347
First Author: Hoover AR
Year: 2016
Journal: J Biol Chem
Title: MicroRNA-205 Maintains T Cell Development following Stress by Regulating Forkhead Box N1 and Selected Chemokines.
Volume: 291
Issue: 44
Pages: 23237-23247
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Publication
18480380 | J:138596
First Author: Miquet JG
Year: 2008
Journal: J Endocrinol
Title: Transgenic mice overexpressing GH exhibit hepatic upregulation of GH-signaling mediators involved in cell proliferation.
Volume: 198
Issue: 2
Pages: 317-30
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Publication
18048479 | J:132302
First Author: Pfluger PT
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure.
Volume: 294
Issue: 3
Pages: G610-8
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Publication
29155981 | J:256397
First Author: Mahbod P
Year: 2018
Journal: Endocrinology
Title: Desacyl Ghrelin Decreases Anxiety-like Behavior in Male Mice.
Volume: 159
Issue: 1
Pages: 388-399
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Publication
14726438 | J:105653
First Author: Iida K
Year: 2004
Journal: Endocrinology
Title: Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist.
Volume: 145
Issue: 4
Pages: 1564-70
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Publication
15644570 | J:103494
First Author: Itoh E
Year: 2004
Journal: Endocr J
Title: Diurnal variation in growth hormone receptor messenger ribonucleic acid in liver and skeletal muscle of lit/+ and lit/lit mice.
Volume: 51
Issue: 6
Pages: 529-35
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Publication
32229232 | J:293151
 
First Author: Wasinski F
Year: 2020
Journal: Neuroscience
Title: Growth Hormone Receptor Deletion Reduces the Density of Axonal Projections from Hypothalamic Arcuate Nucleus Neurons.
Volume: 434
Pages: 136-147
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Publication
21054685 | J:189724
First Author: Clifford S
Year: 2011
Journal: Addict Biol
Title: Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice.
Volume: 16
Issue: 3
Pages: 386-92
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Publication
34042217 | J:330298
First Author: Nakagawa Y
Year: 2021
Journal: FASEB J
Title: Starvation-induced transcription factor CREBH negatively governs body growth by controlling GH signaling.
Volume: 35
Issue: 6
Pages: e21663
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Publication
28946616 | J:310152
 
First Author: Soendergaard C
Year: 2017
Journal: Int J Mol Sci
Title: Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis.
Volume: 18
Issue: 10
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Publication
15887111 | J:124938
First Author: DiFedele LM
Year: 2005
Journal: Gastroenterology
Title: Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis.
Volume: 128
Issue: 5
Pages: 1278-91
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Publication
24895283 | J:215330
First Author: Zhao Y
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1β.
Volume: 307
Issue: 2
Pages: E186-98
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Publication
17698843 | J:126795
First Author: DiGirolamo DJ
Year: 2007
Journal: J Biol Chem
Title: Mode of growth hormone action in osteoblasts.
Volume: 282
Issue: 43
Pages: 31666-74
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Publication
31099824 | J:277565
First Author: List EO
Year: 2019
Journal: Endocrinology
Title: GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.
Volume: 160
Issue: 7
Pages: 1743-1756
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Publication
23169610 | J:312520
First Author: Lee C
Year: 2013
Journal: Drug Metab Dispos
Title: The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene.
Volume: 41
Issue: 2
Pages: 457-65
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Publication
24302626 | J:208707
First Author: Gan Y
Year: 2014
Journal: Endocrinology
Title: Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells.
Volume: 155
Issue: 3
Pages: 1000-9
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Publication
27679560 | J:249704
First Author: Liu Z
Year: 2016
Journal: Diabetes
Title: Growth Hormone Control of Hepatic Lipid Metabolism.
Volume: 65
Issue: 12
Pages: 3598-3609
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Publication
32994489 | J:296256
First Author: Petrescu AD
Year: 2020
Journal: Sci Rep
Title: Ghrelin reverses ductular reaction and hepatic fibrosis in a rodent model of cholestasis.
Volume: 10
Issue: 1
Pages: 16024
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Publication
10713692 | J:61205
First Author: Wennbo H
Year: 2000
Journal: Oncogene
Title: The role of prolactin and growth hormone in breast cancer.
Volume: 19
Issue: 8
Pages: 1072-6
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Publication
7534308 | J:23771
First Author: Wang X
Year: 1995
Journal: J Biol Chem
Title: A 40-amino acid segment of the growth hormone receptor cytoplasmic domain is essential for GH-induced tyrosine-phosphorylated cytosolic proteins.
Volume: 270
Issue: 11
Pages: 6261-6
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Publication
9228076 | J:41958
First Author: Martini JF
Year: 1997
Journal: J Biol Chem
Title: Monkey growth hormone (GH) receptor gene expression. Evidence for two mechanisms for the generation of the GH binding protein.
Volume: 272
Issue: 30
Pages: 18951-8
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Publication
9389738 | J:45260
First Author: Wennbo H
Year: 1997
Journal: J Clin Invest
Title: Activation of the prolactin receptor but not the growth hormone receptor is important for induction of mammary tumors in transgenic mice.
Volume: 100
Issue: 11
Pages: 2744-51
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Publication
9632636 | J:48313
First Author: Moutoussamy S
Year: 1998
Journal: J Biol Chem
Title: Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins.
Volume: 273
Issue: 26
Pages: 15906-12
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Publication
11796490 | J:74981
First Author: González L
Year: 2002
Journal: Endocrinology
Title: Cytokine-inducible SH2 protein up-regulation is associated with desensitization of GH signaling in GHRH-transgenic mice.
Volume: 143
Issue: 2
Pages: 386-94
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Publication
31479305 | J:283666
First Author: Teixeira PDS
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Central growth hormone action regulates metabolism during pregnancy.
Volume: 317
Issue: 5
Pages: E925-E940
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Publication
33755309 | J:304759
First Author: Icyuz M
Year: 2021
Journal: Aging Cell
Title: Physiological and metabolic characteristics of novel double-mutant female mice with targeted disruption of both growth hormone-releasing hormone and growth hormone receptor.
Volume: 20
Issue: 4
Pages: e13339
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Publication
8195244 | J:310266
First Author: Chen WY
Year: 1994
Journal: J Biol Chem
Title: In vitro and in vivo studies of antagonistic effects of human growth hormone analogs.
Volume: 269
Issue: 22
Pages: 15892-7
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Publication
33291663 | J:310262
 
First Author: Qian Y
Year: 2020
Journal: Cancers (Basel)
Title: Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo.
Volume: 12
Issue: 12
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Publication
26657864 | J:230033
First Author: Lagarrigue S
Year: 2016
Journal: J Clin Invest
Title: CDK4 is an essential insulin effector in adipocytes.
Volume: 126
Issue: 1
Pages: 335-48
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Publication
25267913 | J:225860
First Author: Martinez-Espinosa PL
Year: 2014
Journal: J Gen Physiol
Title: Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity.
Volume: 144
Issue: 4
Pages: 275-95
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Publication
26371508 | J:226997
   
First Author: Bebee TW
Year: 2015
Journal: Elife
Title: The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.
Volume: 4
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Publication
29053787 | J:249965
First Author: Devoy A
Year: 2017
Journal: Brain
Title: Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.
Volume: 140
Issue: 11
Pages: 2797-2805
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Publication
30401915 | J:266804
First Author: Tahara N
Year: 2018
Journal: Sci Rep
Title: Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice.
Volume: 8
Issue: 1
Pages: 16410
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Publication
26639755 | J:250501
 
First Author: Horikawa S
Year: 2015
Journal: Sci Rep
Title: PDGFRα plays a crucial role in connective tissue remodeling.
Volume: 5
Pages: 17948
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Publication
25016316 | J:244465
First Author: Crowley JJ
Year: 2015
Journal: Biol Psychiatry
Title: Disruption of the microRNA 137 primary transcript results in early embryonic lethality in mice.
Volume: 77
Issue: 2
Pages: e5-7
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Publication
30625319 | J:283769
First Author: Ebstein SY
Year: 2019
Journal: Cell Rep
Title: Mutant TDP-43 Causes Early-Stage Dose-Dependent Motor Neuron Degeneration in a TARDBP Knockin Mouse Model of ALS.
Volume: 26
Issue: 2
Pages: 364-373.e4
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Publication
28219987 | J:240544
First Author: de Kloet AD
Year: 2017
Journal: J Neurosci
Title: A Unique "Angiotensin-Sensitive" Neuronal Population Coordinates Neuroendocrine, Cardiovascular, and Behavioral Responses to Stress.
Volume: 37
Issue: 13
Pages: 3478-3490
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Publication
36098436 | J:330012
First Author: Bretes E
Year: 2022
Journal: FASEB J
Title: Cystathionine β-synthase gene inactivation dysregulates major urinary protein biogenesis and impairs sexual signaling in mice.
Volume: 36
Issue: 10
Pages: e22547
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Publication
27825319 | J:319224
First Author: Chien CH
Year: 2016
Journal: BMC Cancer
Title: Growth hormone is increased in the lungs and enhances experimental lung metastasis of melanoma in DJ-1 KO mice.
Volume: 16
Issue: 1
Pages: 871
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Publication
7782332 | J:143703
First Author: Argetsinger LS
Year: 1995
Journal: J Biol Chem
Title: Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1.
Volume: 270
Issue: 24
Pages: 14685-92
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Publication
17761766 | J:145813
First Author: Loesch K
Year: 2007
Journal: Endocrinology
Title: Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells.
Volume: 148
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