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Search results 1 to 100 out of 2138 for Nkx2-1

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Publication
First Author: Zhao Y
Year: 2014
Journal: Dev Biol
Title: Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.
Volume: 385
Issue: 1
Pages: 94-106
Publication
First Author: Yee CL
Year: 2009
Journal: J Comp Neurol
Title: Arcuate nucleus expression of NKX2.1 and DLX and lineages expressing these transcription factors in neuropeptide Y(+), proopiomelanocortin(+), and tyrosine hydroxylase(+) neurons in neonatal and adult mice.
Volume: 517
Issue: 1
Pages: 37-50
Publication
First Author: Xing Y
Year: 2008
Journal: Dev Biol
Title: Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten.
Volume: 320
Issue: 2
Pages: 340-50
Publication
First Author: Haji N
Year: 2020
Journal: Mol Autism
Title: Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Volume: 11
Issue: 1
Pages: 29
Publication  
First Author: Minocha S
Year: 2017
Journal: Sci Rep
Title: Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development.
Volume: 7
Pages: 43093
Publication
First Author: Li C
Year: 2013
Journal: Dev Biol
Title: Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.
Volume: 378
Issue: 1
Pages: 13-24
Publication
First Author: Herriges MJ
Year: 2017
Journal: Genes Dev
Title: The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.
Volume: 31
Issue: 9
Pages: 889-903
Publication
First Author: Du T
Year: 2008
Journal: Development
Title: NKX2.1 specifies cortical interneuron fate by activating Lhx6.
Volume: 135
Issue: 8
Pages: 1559-67
Publication
First Author: Minoo P
Year: 2007
Journal: Mol Cell Biol
Title: Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.
Volume: 27
Issue: 6
Pages: 2155-65
Publication
First Author: Little DR
Year: 2021
Journal: Nat Commun
Title: Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.
Volume: 12
Issue: 1
Pages: 2509
Publication
First Author: Kim E
Year: 2019
Journal: Dev Cell
Title: Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation.
Volume: 51
Issue: 6
Pages: 675-683.e4
Publication
First Author: Snyder EL
Year: 2013
Journal: Mol Cell
Title: Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Volume: 50
Issue: 2
Pages: 185-99
Publication
First Author: Caswell DR
Year: 2018
Journal: Mol Cancer Res
Title: Tumor Suppressor Activity of Selenbp1, a Direct Nkx2-1 Target, in Lung Adenocarcinoma.
Volume: 16
Issue: 11
Pages: 1737-1749
Publication
First Author: Mollaoglu G
Year: 2018
Journal: Immunity
Title: The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment.
Volume: 49
Issue: 4
Pages: 764-779.e9
Publication
First Author: Flandin P
Year: 2010
Journal: J Neurosci
Title: The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.
Volume: 30
Issue: 8
Pages: 2812-23
Publication
First Author: Orquera DP
Year: 2019
Journal: J Neurosci
Title: The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus.
Volume: 39
Issue: 21
Pages: 4023-4035
Publication
First Author: Magno L
Year: 2017
Journal: Cell Rep
Title: NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory.
Volume: 20
Issue: 7
Pages: 1572-1584
Publication
First Author: Li E
Year: 2021
Journal: Dev Dyn
Title: Blastocyst complementation reveals that NKX2-1 establishes the proximal-peripheral boundary of the airway epithelium.
Volume: 250
Issue: 7
Pages: 1001-1020
Publication
First Author: Nery S
Year: 2003
Journal: Cereb Cortex
Title: Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon.
Volume: 13
Issue: 9
Pages: 895-903
Publication
First Author: Hoshi S
Year: 2009
Journal: Carcinogenesis
Title: Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.
Volume: 30
Issue: 9
Pages: 1614-9
Publication
First Author: Sandberg M
Year: 2016
Journal: Neuron
Title: Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.
Volume: 91
Issue: 6
Pages: 1260-1275
Publication
First Author: Yin Z
Year: 2006
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression.
Volume: 291
Issue: 2
Pages: L191-9
Publication
First Author: Tomita T
Year: 2008
Journal: J Biol Chem
Title: CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.
Volume: 283
Issue: 37
Pages: 25617-27
Publication
First Author: Butt SJ
Year: 2008
Journal: Neuron
Title: The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.
Volume: 59
Issue: 5
Pages: 722-32
Publication
First Author: Corbin JG
Year: 2003
Journal: Development
Title: Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning.
Volume: 130
Issue: 20
Pages: 4895-906
Publication
First Author: Nóbrega-Pereira S
Year: 2008
Journal: Neuron
Title: Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.
Volume: 59
Issue: 5
Pages: 733-45
Publication
First Author: Sussel L
Year: 1999
Journal: Development
Title: Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.
Volume: 126
Issue: 15
Pages: 3359-70
Publication
First Author: Maeda Y
Year: 2012
Journal: J Clin Invest
Title: Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
Volume: 122
Issue: 12
Pages: 4388-400
Publication
First Author: Ferri A
Year: 2013
Journal: Development
Title: Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh.
Volume: 140
Issue: 6
Pages: 1250-61
Publication
First Author: Krude H
Year: 2002
Journal: J Clin Invest
Title: Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency.
Volume: 109
Issue: 4
Pages: 475-80
Publication  
First Author: Magno L
Year: 2009
Journal: Brain Res
Title: Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: potential for understanding NKX2.1 haploinsufficiency in humans?
Volume: 1304
Pages: 164-86
Gene
Type: gene
Organism: human
Publication
First Author: Jia S
Year: 2020
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: Nkx2.1 downregulation is involved in brain abnormality induced by excess retinoic acid.
Volume: 52
Issue: 6
Pages: 683-690
Publication
First Author: Toth A
Year: 2023
Journal: Nat Commun
Title: Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration.
Volume: 14
Issue: 1
Pages: 8452
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Xu Q
Year: 2008
Journal: J Comp Neurol
Title: Fate mapping Nkx2.1-lineage cells in the mouse telencephalon.
Volume: 506
Issue: 1
Pages: 16-29
Publication
First Author: Heinrich G
Year: 2014
Journal: Diabetes
Title: Preserved energy balance in mice lacking FoxO1 in neurons of Nkx2.1 lineage reveals functional heterogeneity of FoxO1 signaling within the hypothalamus.
Volume: 63
Issue: 5
Pages: 1572-82
Publication
First Author: McSweeney C
Year: 2020
Journal: Transl Psychiatry
Title: Full function of exon junction complex factor, Rbm8a, is critical for interneuron development.
Volume: 10
Issue: 1
Pages: 379
Publication
First Author: Ma T
Year: 2021
Journal: Neuron
Title: Decoding neuronal composition and ontogeny of individual hypothalamic nuclei.
Volume: 109
Issue: 7
Pages: 1150-1167.e6
Publication
First Author: Schoultz E
Year: 2023
Journal: iScience
Title: Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor.
Volume: 26
Issue: 7
Pages: 107071
Publication
First Author: Siddiqi F
Year: 2021
Journal: Cereb Cortex
Title: Islet1 Precursors Contribute to Mature Interneuron Subtypes in Mouse Neocortex.
Volume: 31
Issue: 11
Pages: 5206-5224
Publication  
First Author: Carney RS
Year: 2010
Journal: Neural Dev
Title: Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala.
Volume: 5
Pages: 14
Gene
Type: gene
Organism: human
GXD Expression  
Probe: MGI:7461076
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7548437
Age: embryonic day 14.0
Image: 2A Nkx2.1
Specimen Label: 2A Nkx2.1
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:2676171
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6755212
Age: embryonic day 11.5
Image: 4D Aurkb Ct Nkx2.1
Specimen Label: 4D Aurkb Ct Nkx2.1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:2676171
Assay Type: Immunohistochemistry
Annotation Date: 2021-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6755212
Age: embryonic day 11.5
Image: 4D Aurkb Shh-Cre Nkx2.1
Note: Expression in remnant ot trachea, indicating separation of trachea from esophagus and lung specification had occurred.
Specimen Label: 4D Aurkb Shh-Cre Nkx2.1
Detected: true
Specimen Num: 2
Gene
Type: gene
Organism: Not Specified
Publication
First Author: Favuzzi E
Year: 2019
Journal: Science
Title: Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits.
Volume: 363
Issue: 6425
Pages: 413-417
Publication
First Author: Amendola E
Year: 2010
Journal: Endocrinology
Title: A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid.
Volume: 151
Issue: 4
Pages: 1948-58
Publication
First Author: Biben C
Year: 2002
Journal: Int J Dev Biol
Title: NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis.
Volume: 46
Issue: 4
Pages: 415-22
Publication
First Author: Varma S
Year: 2012
Journal: J Biol Chem
Title: The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.
Volume: 287
Issue: 44
Pages: 37282-95
Publication
First Author: Afink GB
Year: 2010
Journal: Thyroid
Title: Initial characterization of C16orf89, a novel thyroid-specific gene.
Volume: 20
Issue: 7
Pages: 811-21
Publication
First Author: Elbert A
Year: 2019
Journal: J Neurosci
Title: CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.
Volume: 39
Issue: 1
Pages: 177-192
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Magno L
Year: 2011
Journal: Eur J Neurosci
Title: The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1.
Volume: 34
Issue: 11
Pages: 1767-82
Publication
First Author: McKinsey GL
Year: 2013
Journal: Neuron
Title: Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons.
Volume: 77
Issue: 1
Pages: 83-98
Publication
First Author: Kaur N
Year: 2020
Journal: Neuron
Title: Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold.
Volume: 107
Issue: 6
Pages: 1197-1211.e9
Publication
First Author: Morello F
Year: 2015
Journal: J Neurosci
Title: Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development.
Volume: 35
Issue: 42
Pages: 14205-19
Publication
First Author: Aujla PK
Year: 2013
Journal: Development
Title: Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons.
Volume: 140
Issue: 17
Pages: 3511-21
Publication    
First Author: Turrero García M
Year: 2021
Journal: Elife
Title: Transcriptional profiling of sequentially generated septal neuron fates.
Volume: 10
Publication
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
Publication
First Author: Liu Z
Year: 2019
Journal: Cereb Cortex
Title: Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development.
Volume: 29
Issue: 6
Pages: 2653-2667
Publication
First Author: Huisman C
Year: 2021
Journal: Nat Commun
Title: The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus.
Volume: 12
Issue: 1
Pages: 256
Publication    
First Author: Mancia Leon WR
Year: 2020
Journal: Elife
Title: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.
Volume: 9
Publication
First Author: Xing Y
Year: 2010
Journal: Development
Title: Signaling via Alk5 controls the ontogeny of lung Clara cells.
Volume: 137
Issue: 5
Pages: 825-33
Publication
First Author: Gelman DM
Year: 2009
Journal: J Neurosci
Title: The embryonic preoptic area is a novel source of cortical GABAergic interneurons.
Volume: 29
Issue: 29
Pages: 9380-9
Publication  
First Author: Murthy S
Year: 2014
Journal: Nat Commun
Title: Serotonin receptor 3A controls interneuron migration into the neocortex.
Volume: 5
Pages: 5524
Publication
First Author: Chen L
Year: 2010
Journal: J Neurosci
Title: The mouse homeobox gene Gbx2 is required for the development of cholinergic interneurons in the striatum.
Volume: 30
Issue: 44
Pages: 14824-34
Publication  
First Author: Yin W
Year: 2022
Journal: Development
Title: An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.
Volume: 149
Issue: 3
Publication
First Author: Tinterri A
Year: 2018
Journal: J Comp Neurol
Title: Tangential migration of corridor guidepost neurons contributes to anxiety circuits.
Volume: 526
Issue: 3
Pages: 397-411
Publication
First Author: Kim YJ
Year: 2018
Journal: Neuron
Title: Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory.
Volume: 100
Issue: 5
Pages: 1180-1193.e6
Publication
First Author: Pai EL
Year: 2019
Journal: Cell Rep
Title: Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function.
Volume: 26
Issue: 5
Pages: 1157-1173.e5
Publication  
First Author: Knowles SJ
Year: 2023
Journal: Development
Title: Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs.
Volume: 150
Issue: 10
Publication      
First Author: Mayerl S
Year: 2021
Journal: Cereb Cortex
Title: Thyroid Hormone Transporter Deficiency in Mice Impacts Multiple Stages of GABAergic Interneuron Development.
Publication
First Author: Chung C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis.
Volume: 110
Issue: 19
Pages: 7732-7
Publication
First Author: Lim L
Year: 2018
Journal: Nat Neurosci
Title: Optimization of interneuron function by direct coupling of cell migration and axonal targeting.
Volume: 21
Issue: 7
Pages: 920-931
Publication
First Author: Hoch RV
Year: 2015
Journal: Cell Rep
Title: OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum.
Volume: 12
Issue: 3
Pages: 482-94
Publication
First Author: Ma T
Year: 2012
Journal: Cereb Cortex
Title: A subpopulation of dorsal lateral/caudal ganglionic eminence-derived neocortical interneurons expresses the transcription factor Sp8.
Volume: 22
Issue: 9
Pages: 2120-30
Publication
First Author: Cho HH
Year: 2014
Journal: PLoS Genet
Title: Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes.
Volume: 10
Issue: 4
Pages: e1004280
Publication
First Author: Mortensen AH
Year: 2015
Journal: Hum Mol Genet
Title: Deletion of OTX2 in neural ectoderm delays anterior pituitary development.
Volume: 24
Issue: 4
Pages: 939-53
Publication
First Author: Newman EA
Year: 2018
Journal: Dev Biol
Title: Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.
Volume: 442
Issue: 2
Pages: 236-248
Publication
First Author: Lin C
Year: 2015
Journal: Dev Biol
Title: A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth.
Volume: 403
Issue: 1
Pages: 101-13
Publication
First Author: Correa SM
Year: 2015
Journal: Cell Rep
Title: An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females.
Volume: 10
Issue: 1
Pages: 62-74
Publication
First Author: Fujiyama T
Year: 2018
Journal: Cell Rep
Title: Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain.
Volume: 24
Issue: 1
Pages: 79-94
Publication
First Author: Cheffer A
Year: 2023
Journal: Cereb Cortex
Title: DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons.
Volume: 33
Issue: 19
Pages: 10272-10285
Publication
First Author: Hu JS
Year: 2017
Journal: Development
Title: Coup-TF1 and Coup-TF2 control subtype and laminar identity of MGE-derived neocortical interneurons.
Volume: 144
Issue: 15
Pages: 2837-2851
Publication  
First Author: Tao G
Year: 2019
Journal: Front Mol Neurosci
Title: Transcription Factors Sp8 and Sp9 Regulate Medial Ganglionic Eminence-Derived Cortical Interneuron Migration.
Volume: 12
Pages: 75
Publication
First Author: Tiozzo C
Year: 2009
Journal: Am J Respir Crit Care Med
Title: Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.
Volume: 180
Issue: 8
Pages: 701-12
Publication
First Author: Delgado RN
Year: 2020
Journal: Science
Title: Maintenance of neural stem cell positional identity by mixed-lineage leukemia 1.
Volume: 368
Issue: 6486
Pages: 48-53
Publication
First Author: Tiozzo C
Year: 2012
Journal: Endocr Relat Cancer
Title: Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner.
Volume: 19
Issue: 2
Pages: 111-122
Publication
First Author: Boucherat O
Year: 2015
Journal: Development
Title: Epithelial inactivation of Yy1 abrogates lung branching morphogenesis.
Volume: 142
Issue: 17
Pages: 2981-95
Publication  
First Author: Wei B
Year: 2012
Journal: Neuroscience
Title: The onion skin-like organization of the septum arises from multiple embryonic origins to form multiple adult neuronal fates.
Volume: 222
Pages: 110-23
Publication  
First Author: Liang S
Year: 2018
Journal: Development
Title: A branching morphogenesis program governs embryonic growth of the thyroid gland.
Volume: 145
Issue: 2
Publication
First Author: Cai Y
Year: 2013
Journal: J Comp Neurol
Title: Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons.
Volume: 521
Issue: 2
Pages: 479-97
Publication
First Author: McKenzie MG
Year: 2019
Journal: Neuron
Title: Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons.
Volume: 103
Issue: 5
Pages: 853-864.e4
Publication  
First Author: Rhodes CT
Year: 2024
Journal: Front Cell Neurosci
Title: Loss of Ezh2 in the medial ganglionic eminence alters interneuron fate, cell morphology and gene expression profiles.
Volume: 18
Pages: 1334244
Publication
First Author: Lee B
Year: 2016
Journal: Development
Title: The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons.
Volume: 143
Issue: 20
Pages: 3763-3773
Publication
First Author: Tuncdemir SN
Year: 2015
Journal: Cereb Cortex
Title: miRNAs are Essential for the Survival and Maturation of Cortical Interneurons.
Volume: 25
Issue: 7
Pages: 1842-57
Publication
First Author: Marfull-Oromí P
Year: 2021
Journal: J Neurochem
Title: Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation.
Volume: 158
Issue: 2
Pages: 197-216
Publication
First Author: Nunnelly LF
Year: 2022
Journal: Nat Commun
Title: St18 specifies globus pallidus projection neuron identity in MGE lineage.
Volume: 13
Issue: 1
Pages: 7735