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Search results 101 to 141 out of 141 for Btla

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Type

Details

Score

Publication

- | J:57747

First Author:	MGI Genome Annotation Group and UniGene Staff
Year:	2015
Journal:	Database Download
Title:	MGI-UniGene Interconnection Effort

•

Publication

- | J:75000

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2002

Title:	Mouse Genome Informatics Computational Sequence to Gene Associations

•

Publication

- | J:161428

First Author:	Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year:	2010

Title:	Annotation inferences using phylogenetic trees

•

Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

•

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

Publication

32437509 | J:291319

First Author:	Xu X
Year:	2020
Journal:	J Cell Biol
Title:	PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
Volume:	219
Issue:	6

•

Publication

31189114 | J:291040

First Author:	Celis-Gutierrez J
Year:	2019
Journal:	Cell Rep
Title:	Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Volume:	27
Issue:	11
Pages:	3315-3330.e7

•

Allele

Btla<em1Smoc> | MGI:7288538

Name:	B and T lymphocyte associated; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

•

Strain

MGI:6354566 | C57BL/6J-Btla<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Allele

Btla<em2(BTLA)Smoc> | MGI:7288539

Name:	B and T lymphocyte associated; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Humanized sequence, Inserted expressed sequence

•

Strain

MGI:6354565 | C57BL/6J-Btla<em2(BTLA)Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Publication

21543122 | J:174276

First Author:	Lindvall T
Year:	2011
Journal:	J Neuroimmunol
Title:	An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes.
Volume:	235
Issue:	1-2
Pages:	40-7

•

Publication

31332204 | J:279316

First Author:	Kim TJ
Year:	2019
Journal:	Nat Commun
Title:	CD160 serves as a negative regulator of NKT cells in acute hepatic injury.
Volume:	10
Issue:	1
Pages:	3258

•

Publication

27693350 | J:253608

First Author:	Boice M
Year:	2016
Journal:	Cell
Title:	Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells.
Volume:	167
Issue:	2
Pages:	405-418.e13

•

Publication

34709351 | J:342719

First Author:	Liu W
Year:	2021
Journal:	J Exp Med
Title:	HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
Volume:	218
Issue:	12

•

Publication

26811456 | J:230446

First Author:	Ho PP
Year:	2016
Journal:	Proc Natl Acad Sci U S A
Title:	Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis.
Volume:	113
Issue:	6
Pages:	1600-5

•

Publication

9462508 | -

First Author:	Mauri DN
Year:	1998
Journal:	Immunity
Title:	LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator.
Volume:	8
Issue:	1
Pages:	21-30

•

Publication

19426226 | -

First Author:	Cai G
Year:	2009
Journal:	Immunol Rev
Title:	The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T-cell activation.
Volume:	229
Issue:	1
Pages:	244-58

•

Publication

24851095 | -

First Author:	Shui JW
Year:	2014
Journal:	Immune Netw
Title:	HVEM is a TNF Receptor with Multiple Regulatory Roles in the Mucosal Immune System.
Volume:	14
Issue:	2
Pages:	67-72

•

Publication

22445654 | -

First Author:	Pasero C
Year:	2012
Journal:	Curr Opin Pharmacol
Title:	The HVEM network: new directions in targeting novel costimulatory/co-inhibitory molecules for cancer therapy.
Volume:	12
Issue:	4
Pages:	478-85

•

Publication

23439006 | -

First Author:	Pasero C
Year:	2013
Journal:	Immunol Lett
Title:	Interfering with coinhibitory molecules: BTLA/HVEM as new targets to enhance anti-tumor immunity.
Volume:	151
Issue:	1-2
Pages:	71-5

•

Publication

16131544 | -

First Author:	Cheung TC
Year:	2005
Journal:	Proc Natl Acad Sci U S A
Title:	Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway.
Volume:	102
Issue:	37
Pages:	13218-23

•

Protein Domain

IPR034031 | TNFRSF14/UL144_N

Type:

Domain

Description:

Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as herpes virus entry mediator or HVEM, ATAR, CD270, HVEA, LIGHTR or TR2, regulates T-cell immune responses by activating inflammatory, as well as inhibitory signaling pathways. HVEM acts as a receptor for the canonical TNF-related ligand LIGHT (lymphotoxin-like), which exhibits inducible expression, and competes with herpes simplex virus glycoprotein D for HVEM [, ]. It also acts as a ligand for the immunoglobulin superfamily proteins BTLA (B and T lymphocyte attenuator) and CD160, a feature distinguishing HVEM from other immune regulatory molecules, thus, creating a functionally diverse set of intrinsic and bidirectional signaling pathways [].HVEM is highly expressed in the gut epithelium. Genome-wide association studies have shown that HVEM is an inflammatory bowel disease (IBD) risk gene, suggesting that HVEM could have a regulatory role influencing the regulation of epithelial barrier, host defense, and the microbiota []. Mouse models have revealed that HVEM is involved in colitis pathogenesis, mucosal host defense, and epithelial immunity, thus acting as a mucosal gatekeeper with multiple regulatory functions in the mucosa. HVEM plays a critical role in both tumor progression and resistance to antitumor immune responses, possibly through direct and indirect mechanisms. It is known to be expressed in several human malignancies, including esophageal squamous cell carcinoma, follicular lymphoma and melanoma. HVEM network may therefore be an attractive target for drug intervention [, ].TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].This entry represents the N-terminal domain of TNFRSF14, and is also found in the orphan TNFR, UL144, present in human Cytomegalovirus. UL144 binds BTLA, but not LIGHT, and inhibits T cell proliferation, selectively mimicking the inhibitory cosignaling function of HVEM [].

•

Publication

8898196 | -

First Author:	Montgomery RI
Year:	1996
Journal:	Cell
Title:	Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family.
Volume:	87
Issue:	3
Pages:	427-36

•

Protein

Q80WM9

Organism:	Mus musculus/domesticus
Length:	275
Fragment?:	false

•

Protein

Q71F55

Organism:	Mus musculus/domesticus
Length:	276
Fragment?:	false

•

Protein

Q3SXX1

Organism:	Mus musculus/domesticus
Length:	275
Fragment?:	false

•

Protein

A0A1W2P7D5

Organism:	Mus musculus/domesticus
Length:	276
Fragment?:	false

•

Protein

A0A1W2P889

Organism:	Mus musculus/domesticus
Length:	108
Fragment?:	true

•

Publication

9538693 | -

First Author:	Naismith JH
Year:	1998
Journal:	Trends Biochem Sci
Title:	Modularity in the TNF-receptor family.
Volume:	23
Issue:	2
Pages:	74-9

•

Publication

11796220 | -

First Author:	Bodmer JL
Year:	2002
Journal:	Trends Biochem Sci
Title:	The molecular architecture of the TNF superfamily.
Volume:	27
Issue:	1
Pages:	19-26

•

Publication

8387891 | -

First Author:	Banner DW
Year:	1993
Journal:	Cell
Title:	Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume:	73
Issue:	3
Pages:	431-45

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

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