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Search results 201 to 300 out of 1081 for Htt

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Type Details Score
Publication
First Author: Kovalenko M
Year: 2012
Journal: PLoS One
Title: Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
Volume: 7
Issue: 9
Pages: e44273
Publication
First Author: McFarland KN
Year: 2014
Journal: Hum Mol Genet
Title: MeCP2: a novel Huntingtin interactor.
Volume: 23
Issue: 4
Pages: 1036-44
Publication  
First Author: Agostoni E
Year: 2016
Journal: Front Cell Neurosci
Title: Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice.
Volume: 10
Pages: 110
Publication
First Author: Tang B
Year: 2012
Journal: Hum Mol Genet
Title: Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.
Volume: 21
Issue: 14
Pages: 3097-111
Publication
First Author: Chiang MC
Year: 2007
Journal: Hum Mol Genet
Title: Dysregulation of C/EBPalpha by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.
Volume: 16
Issue: 5
Pages: 483-98
Publication
First Author: Ju TC
Year: 2014
Journal: Biochim Biophys Acta
Title: AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease.
Volume: 1842
Issue: 9
Pages: 1668-80
Publication
First Author: Tallaksen-Greene SJ
Year: 2005
Journal: Neuroscience
Title: Neuronal intranuclear inclusions and neuropil aggregates in HdhCAG(150) knockin mice.
Volume: 131
Issue: 4
Pages: 843-52
Publication
First Author: Parsons MP
Year: 2014
Journal: J Biol Chem
Title: Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin.
Volume: 289
Issue: 6
Pages: 3518-28
Publication
First Author: Soldati C
Year: 2013
Journal: J Neurochem
Title: Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease.
Volume: 124
Issue: 3
Pages: 418-30
Publication  
First Author: Yao J
Year: 2014
Journal: Mol Cell Neurosci
Title: Huntingtin is associated with cytomatrix proteins at the presynaptic terminal.
Volume: 63
Pages: 96-100
Publication  
First Author: Swarnkar S
Year: 2015
Journal: Neurobiol Dis
Title: Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
Volume: 82
Pages: 66-77
Publication
First Author: Lee H
Year: 2020
Journal: Neuron
Title: Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Volume: 107
Issue: 5
Pages: 891-908.e8
Publication
First Author: Goold R
Year: 2021
Journal: Cell Rep
Title: FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Volume: 36
Issue: 9
Pages: 109649
Publication
First Author: Morfini GA
Year: 2009
Journal: Nat Neurosci
Title: Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.
Volume: 12
Issue: 7
Pages: 864-71
Publication
First Author: Choudhury KR
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity.
Volume: 456
Issue: 1
Pages: 66-73
Publication
First Author: Gerson JE
Year: 2020
Journal: Hum Mol Genet
Title: Ubiquilin-2 differentially regulates polyglutamine disease proteins.
Volume: 29
Issue: 15
Pages: 2596-2610
Publication
First Author: Jiang M
Year: 2020
Journal: Hum Mol Genet
Title: Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
Volume: 29
Issue: 8
Pages: 1340-1352
Publication
First Author: Dietrich P
Year: 2009
Journal: Hum Mol Genet
Title: Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages.
Volume: 18
Issue: 1
Pages: 142-50
Publication
First Author: Caviston JP
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Volume: 104
Issue: 24
Pages: 10045-50
Publication
First Author: Cho KJ
Year: 2009
Journal: Neuroscience
Title: Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
Volume: 163
Issue: 4
Pages: 1128-34
Publication
First Author: Crook ZR
Year: 2011
Journal: Neuron
Title: Huntington's disease: can mice lead the way to treatment?
Volume: 69
Issue: 3
Pages: 423-35
Publication  
First Author: Pan Y
Year: 2016
Journal: Sci Rep
Title: Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity.
Volume: 6
Pages: 31022
Publication
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
Publication
First Author: Hachigian LJ
Year: 2017
Journal: Cell Rep
Title: Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2.
Volume: 21
Issue: 10
Pages: 2688-2695
Publication
First Author: Pancani T
Year: 2023
Journal: Nat Commun
Title: Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice.
Volume: 14
Issue: 1
Pages: 1398
Publication
First Author: Miller JP
Year: 2012
Journal: PLoS Genet
Title: A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.
Volume: 8
Issue: 11
Pages: e1003042
Publication
First Author: Keryer G
Year: 2011
Journal: J Clin Invest
Title: Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.
Volume: 121
Issue: 11
Pages: 4372-82
Publication
First Author: Di Pardo A
Year: 2020
Journal: Hum Mol Genet
Title: Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import.
Volume: 29
Issue: 3
Pages: 418-431
Publication
First Author: Gafni J
Year: 2004
Journal: J Biol Chem
Title: Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus.
Volume: 279
Issue: 19
Pages: 20211-20
Publication
First Author: Louis Sam Titus ASC
Year: 2017
Journal: J Neurosci
Title: Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.
Volume: 37
Issue: 27
Pages: 6575-6587
Publication
First Author: de Souza JM
Year: 2020
Journal: Mol Brain
Title: mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease.
Volume: 13
Issue: 1
Pages: 118
Publication
First Author: Yu X
Year: 2020
Journal: Neuron
Title: Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable.
Volume: 108
Issue: 6
Pages: 1146-1162.e10
Publication
First Author: Loupe JM
Year: 2020
Journal: Hum Mol Genet
Title: Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Volume: 29
Issue: 18
Pages: 3044-3053
Publication
First Author: Sanders SS
Year: 2015
Journal: Dev Biol
Title: Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development.
Volume: 397
Issue: 2
Pages: 257-66
Publication
First Author: Plotkin JL
Year: 2014
Journal: Neuron
Title: Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease.
Volume: 83
Issue: 1
Pages: 178-88
Publication
First Author: Näf D
Year: 2001
Journal: Hum Mol Genet
Title: Mouse models for the Wolf-Hirschhorn deletion syndrome.
Volume: 10
Issue: 2
Pages: 91-8
Publication
First Author: Rué L
Year: 2016
Journal: J Clin Invest
Title: Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Volume: 126
Issue: 11
Pages: 4319-4330
Publication
First Author: Kaltenbach LS
Year: 2007
Journal: PLoS Genet
Title: Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Volume: 3
Issue: 5
Pages: e82
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lin B
Year: 1994
Journal: Hum Mol Genet
Title: Sequence of the murine Huntington disease gene: evidence for conservation, alternate splicing and polymorphism in a triplet (CCG) repeat [corrected].
Volume: 3
Issue: 1
Pages: 85-92
Publication
First Author: Barnes GT
Year: 1994
Journal: Somat Cell Mol Genet
Title: Mouse Huntington's disease gene homolog (Hdh).
Volume: 20
Issue: 2
Pages: 87-97
Publication
First Author: Trottier Y
Year: 1995
Journal: Nat Genet
Title: Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form.
Volume: 10
Issue: 1
Pages: 104-10
Publication
First Author: Lin B
Year: 1995
Journal: Genomics
Title: Structural analysis of the 5' region of mouse and human Huntington disease genes reveals conservation of putative promoter region and di- and trinucleotide polymorphisms.
Volume: 25
Issue: 3
Pages: 707-15
Publication
First Author: Bradford J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms.
Volume: 106
Issue: 52
Pages: 22480-5
Publication
First Author: Zala D
Year: 2013
Journal: Cell
Title: Vesicular glycolysis provides on-board energy for fast axonal transport.
Volume: 152
Issue: 3
Pages: 479-91
Publication
First Author: Díaz-Hernández M
Year: 2005
Journal: J Neurosci
Title: Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease.
Volume: 25
Issue: 42
Pages: 9773-81
Publication
First Author: Martinez-Vicente M
Year: 2010
Journal: Nat Neurosci
Title: Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Volume: 13
Issue: 5
Pages: 567-76
Publication
First Author: Yamamoto A
Year: 2000
Journal: Cell
Title: Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.
Volume: 101
Issue: 1
Pages: 57-66
Publication
First Author: Heng MY
Year: 2009
Journal: J Neurosci
Title: In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease.
Volume: 29
Issue: 10
Pages: 3200-5
Publication
First Author: Merienne N
Year: 2017
Journal: Cell Rep
Title: The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes.
Volume: 20
Issue: 12
Pages: 2980-2991
Publication
First Author: Guidetti P
Year: 2001
Journal: Exp Neurol
Title: Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production.
Volume: 169
Issue: 2
Pages: 340-50
Publication
First Author: Ishiguro H
Year: 2001
Journal: J Neurosci Res
Title: Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
Volume: 65
Issue: 4
Pages: 289-97
Publication  
First Author: Quirion JG
Year: 2019
Journal: Front Cell Neurosci
Title: The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease.
Volume: 13
Pages: 326
Publication
First Author: Graham RK
Year: 2006
Journal: Neurobiol Dis
Title: Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models.
Volume: 21
Issue: 2
Pages: 444-55
Publication  
First Author: Glangetas C
Year: 2020
Journal: eNeuro
Title: Deficit in Motor Skill Consolidation-Dependent Synaptic Plasticity at Motor Cortex to Dorsolateral Striatum Synapses in a Mouse Model of Huntington's Disease.
Volume: 7
Issue: 2
Publication  
First Author: MacDonald ME
Year: 1996
Journal: Cold Spring Harb Symp Quant Biol
Title: Targeted inactivation of the mouse Huntington's disease gene homolog Hdh.
Volume: 61
Pages: 627-38
Publication
First Author: Reiner A
Year: 2001
Journal: J Neurosci
Title: Neurons lacking huntingtin differentially colonize brain and survive in chimeric mice.
Volume: 21
Issue: 19
Pages: 7608-19
Publication
First Author: Ben M'Barek K
Year: 2013
Journal: J Neurosci
Title: Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis.
Volume: 33
Issue: 20
Pages: 8608-20
Publication
First Author: Snider BJ
Year: 2003
Journal: Neuroscience
Title: Neocortical neurons cultured from mice with expanded CAG repeats in the huntingtin gene: unaltered vulnerability to excitotoxins and other insults.
Volume: 120
Issue: 3
Pages: 617-25
Publication
First Author: Langfelder P
Year: 2016
Journal: Nat Neurosci
Title: Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Volume: 19
Issue: 4
Pages: 623-33
Publication
First Author: Brustovetsky N
Year: 2005
Journal: J Neurochem
Title: Age-dependent changes in the calcium sensitivity of striatal mitochondria in mouse models of Huntington's Disease.
Volume: 93
Issue: 6
Pages: 1361-70
Publication
First Author: Langfelder P
Year: 2018
Journal: PLoS One
Title: MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.
Volume: 13
Issue: 1
Pages: e0190550
Publication
First Author: Deng YP
Year: 2016
Journal: J Comp Neurol
Title: Cholinergic interneurons in the Q140 knockin mouse model of Huntington's disease: Reductions in dendritic branching and thalamostriatal input.
Volume: 524
Issue: 17
Pages: 3518-3529
Publication
First Author: Kegel KB
Year: 2009
Journal: J Neurochem
Title: Polyglutamine expansion in huntingtin alters its interaction with phospholipids.
Volume: 110
Issue: 5
Pages: 1585-97
Publication
First Author: Hickey MA
Year: 2012
Journal: Mol Cell Neurosci
Title: Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease.
Volume: 49
Issue: 2
Pages: 149-57
Publication
First Author: Steinberg N
Year: 2023
Journal: J Neuroinflammation
Title: Naïve Huntington's disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1.
Volume: 20
Issue: 1
Pages: 276
Publication  
First Author: Ravalia AS
Year: 2021
Journal: Neurobiol Dis
Title: Super-resolution imaging reveals extrastriatal synaptic dysfunction in presymptomatic Huntington disease mice.
Volume: 152
Pages: 105293
Publication
First Author: Hickey MA
Year: 2008
Journal: Neuroscience
Title: Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice.
Volume: 157
Issue: 1
Pages: 280-95
Publication  
First Author: Abd-Elrahman KS
Year: 2017
Journal: Sci Signal
Title: mGluR5 antagonism increases autophagy and prevents disease progression in the zQ175 mouse model of Huntington's disease.
Volume: 10
Issue: 510
Publication  
First Author: Schindler F
Year: 2021
Journal: Front Neurosci
Title: Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington's Disease Knock-in Mice.
Volume: 15
Pages: 682172
Publication
First Author: Li SH
Year: 2023
Journal: Mol Brain
Title: Comparison of Huntington's disease phenotype progression in male and female heterozygous FDNQ175 mice.
Volume: 16
Issue: 1
Pages: 67
Publication
First Author: Zhang C
Year: 2020
Journal: Cereb Cortex Commun
Title: Abnormal Brain Development in Huntington' Disease Is Recapitulated in the zQ175 Knock-In Mouse Model.
Volume: 1
Issue: 1
Pages: tgaa044
Publication
First Author: Heikkinen T
Year: 2020
Journal: PLoS One
Title: Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington's disease.
Volume: 15
Issue: 12
Pages: e0243052
Publication  
First Author: Corey-Bloom J
Year: 2017
Journal: Brain Res
Title: Beneficial effects of glatiramer acetate in Huntington's disease mouse models: Evidence for BDNF-elevating and immunomodulatory mechanisms.
Volume: 1673
Pages: 102-110
Publication
First Author: Goodliffe JW
Year: 2018
Journal: PLoS One
Title: Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington's Disease.
Volume: 13
Issue: 8
Pages: e0200626
Publication
First Author: Yang S
Year: 2018
Journal: Cell Rep
Title: Shortening the Half-Life of Cas9 Maintains Its Gene Editing Ability and Reduces Neuronal Toxicity.
Volume: 25
Issue: 10
Pages: 2653-2659.e3
Publication
First Author: Deng Y
Year: 2021
Journal: J Comp Neurol
Title: Progression of basal ganglia pathology in heterozygous Q175 knock-in Huntington's disease mice.
Volume: 529
Issue: 7
Pages: 1327-1371
Publication
First Author: Hong Y
Year: 2017
Journal: J Neurosci
Title: Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes.
Volume: 37
Issue: 39
Pages: 9550-9563
Publication  
First Author: Piiponniemi TO
Year: 2018
Journal: Front Behav Neurosci
Title: Impaired Performance of the Q175 Mouse Model of Huntington's Disease in the Touch Screen Paired Associates Learning Task.
Volume: 12
Pages: 226
Publication
First Author: Friedman A
Year: 2020
Journal: Cell
Title: Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model.
Volume: 183
Issue: 4
Pages: 918-934.e49
Publication
First Author: Marangoni M
Year: 2014
Journal: Neurobiol Aging
Title: Age-related axonal swellings precede other neuropathological hallmarks in a knock-in mouse model of Huntington's disease.
Volume: 35
Issue: 10
Pages: 2382-93
Publication
First Author: Rising AC
Year: 2011
Journal: Exp Neurol
Title: Longitudinal behavioral, cross-sectional transcriptional and histopathological characterization of a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Volume: 228
Issue: 2
Pages: 173-82