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Search results 101 to 200 out of 214 for Best1

0.045s
Type Details Score
DO Term
DO Term
DO Term
Allele  
Name: bestrophin 1; targeted mutation 1.1, Alan Marmorstein
Allele Type: Targeted
Publication
First Author: Storm T
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Selective Ablation of Megalin in the Retinal Pigment Epithelium Results in Megaophthalmos, Macromelanosome Formation and Severe Retina Degeneration.
Volume: 60
Issue: 1
Pages: 322-330
Genotype
Symbol: Best1/Best1
Background: involves: 129X1/SvJ * BALB/c
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Best1/Best1<+>
Background: involves: 129X1/SvJ * BALB/c
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Iacovelli J
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Generation of Cre transgenic mice with postnatal RPE-specific ocular expression.
Volume: 52
Issue: 3
Pages: 1378-83
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Douglas Vollrath
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Strain
Attribute String: mutant stock, targeted mutation
Allele
Name: transgene insertion 1, Yun-Zheng Le
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Transactivator
Allele
Name: transgene insertion 1, Joshua L Dunaief
Allele Type: Transgenic
Attribute String: Recombinase
Publication  
First Author: Chen C
Year: 2018
Journal: Front Genet
Title: Regulation of Nrf2 by X Box-Binding Protein 1 in Retinal Pigment Epithelium.
Volume: 9
Pages: 658
Publication
First Author: Zhong Y
Year: 2012
Journal: PLoS One
Title: X-box binding protein 1 is essential for the anti-oxidant defense and cell survival in the retinal pigment epithelium.
Volume: 7
Issue: 6
Pages: e38616
Publication
First Author: Yang J
Year: 2019
Journal: Diabetologia
Title: Loss of X-box binding protein 1 in Müller cells augments retinal inflammation in a mouse model of diabetes.
Volume: 62
Issue: 3
Pages: 531-543
Publication
First Author: Chen C
Year: 2014
Journal: Antioxid Redox Signal
Title: Role of unfolded protein response dysregulation in oxidative injury of retinal pigment epithelial cells.
Volume: 20
Issue: 14
Pages: 2091-106
Publication
First Author: Ma JH
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions.
Volume: 57
Issue: 13
Pages: 5244-5252
Strain
Attribute String: transgenic, mutant stock
Publication
First Author: Schultz R
Year: 2018
Journal: Sci Rep
Title: Frataxin overexpression in Müller cells protects retinal ganglion cells in a mouse model of ischemia/reperfusion injury in vivo.
Volume: 8
Issue: 1
Pages: 4846
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: He L
Year: 2014
Journal: Am J Pathol
Title: Age- and gene-dosage-dependent cre-induced abnormalities in the retinal pigment epithelium.
Volume: 184
Issue: 6
Pages: 1660-7
Genotype
Symbol: Tg(BEST1-cre)1Jdun/?
Background: C57BL/6-Tg(BEST1-cre)1Jdun
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(BEST1-cre)1Jdun/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Qu Z
Year: 2008
Journal: Am J Physiol Cell Physiol
Title: Bestrophin Cl- channels are highly permeable to HCO3-.
Volume: 294
Issue: 6
Pages: C1371-7
Publication  
First Author: Choi VW
Year: 2015
Journal: Mol Ther Methods Clin Dev
Title: AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice.
Volume: 2
Pages: 15022
Publication  
First Author: Valapala M
Year: 2015
Journal: Sci Rep
Title: βA3/A1-crystallin is a critical mediator of STAT3 signaling in optic nerve astrocytes.
Volume: 5
Pages: 8755
Publication
First Author: Shang P
Year: 2017
Journal: Aging Cell
Title: The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.
Volume: 16
Issue: 2
Pages: 349-359
Publication  
First Author: Ghosh S
Year: 2019
Journal: Commun Biol
Title: Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.
Volume: 2
Pages: 348
Publication
First Author: Ghosh S
Year: 2017
Journal: J Pathol
Title: Activating the AKT2-nuclear factor-κB-lipocalin-2 axis elicits an inflammatory response in age-related macular degeneration.
Volume: 241
Issue: 5
Pages: 583-588
Publication
First Author: Valapala M
Year: 2014
Journal: Autophagy
Title: Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
Volume: 10
Issue: 3
Pages: 480-96
Publication
First Author: Ghosh S
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration.
Volume: 59
Issue: 4
Pages: AMD104-AMD113
Publication
First Author: Valapala M
Year: 2014
Journal: Aging Cell
Title: Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 cKO mice is associated with a chronic inflammatory response.
Volume: 13
Issue: 6
Pages: 1091-4
Publication
First Author: Sethna S
Year: 2016
Journal: J Biol Chem
Title: Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision.
Volume: 291
Issue: 12
Pages: 6494-506
Publication
First Author: Oliveira SDS
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-β-driven pulmonary vascular remodeling.
Volume: 312
Issue: 5
Pages: L760-L771
Publication
First Author: Zhou KK
Year: 2014
Journal: PLoS One
Title: Interruption of Wnt signaling in Müller cells ameliorates ischemia-induced retinal neovascularization.
Volume: 9
Issue: 10
Pages: e108454
Publication    
First Author: Storti F
Year: 2019
Journal: Elife
Title: Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration.
Volume: 8
Publication
First Author: Biswal MR
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD.
Volume: 58
Issue: 2
Pages: 1237-1245
Publication
First Author: Biswal MR
Year: 2018
Journal: PLoS One
Title: Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress.
Volume: 13
Issue: 9
Pages: e0203816
Publication  
First Author: Biswal MR
Year: 2015
Journal: Exp Eye Res
Title: Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress.
Volume: 140
Pages: 94-105
Publication  
First Author: Brown EE
Year: 2019
Journal: Redox Biol
Title: Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors.
Volume: 24
Pages: 101201
Publication  
First Author: Biswal MR
Year: 2016
Journal: Adv Exp Med Biol
Title: Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration.
Volume: 854
Pages: 31-7
Publication
First Author: Fu S
Year: 2015
Journal: Diabetes
Title: Müller Glia Are a Major Cellular Source of Survival Signals for Retinal Neurons in Diabetes.
Volume: 64
Issue: 10
Pages: 3554-63
Publication
First Author: Yao J
Year: 2015
Journal: Autophagy
Title: Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium.
Volume: 11
Issue: 6
Pages: 939-53
Publication
First Author: Lin M
Year: 2011
Journal: Diabetologia
Title: Ischaemia-induced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Müller cells.
Volume: 54
Issue: 6
Pages: 1554-66
Publication
First Author: Bai Y
Year: 2009
Journal: J Pathol
Title: Müller cell-derived VEGF is a significant contributor to retinal neovascularization.
Volume: 219
Issue: 4
Pages: 446-54
Publication
First Author: Wang J
Year: 2010
Journal: Diabetes
Title: Müller cell-derived VEGF is essential for diabetes-induced retinal inflammation and vascular leakage.
Volume: 59
Issue: 9
Pages: 2297-305
Publication
First Author: Zhao C
Year: 2011
Journal: J Clin Invest
Title: mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.
Volume: 121
Issue: 1
Pages: 369-83
Publication
First Author: Bullock J
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R).
Volume: 62
Issue: 2
Pages: 30
Publication
First Author: Huang J
Year: 2019
Journal: Theranostics
Title: Abnormal mTORC1 signaling leads to retinal pigment epithelium degeneration.
Volume: 9
Issue: 4
Pages: 1170-1180
Publication
First Author: Cai J
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: DARPP32, a target of hyperactive mTORC1 in the retinal pigment epithelium.
Volume: 119
Issue: 33
Pages: e2207489119
Publication
First Author: Masuda T
Year: 2014
Journal: J Biol Chem
Title: Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium.
Volume: 289
Issue: 18
Pages: 12908-21
Publication
First Author: Go YM
Year: 2020
Journal: FASEB J
Title: MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium.
Volume: 34
Issue: 9
Pages: 12502-12520
Publication
First Author: Swarup A
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Modulating GLUT1 expression in retinal pigment epithelium decreases glucose levels in the retina: impact on photoreceptors and Müller glial cells.
Volume: 316
Issue: 1
Pages: C121-C133
Genotype
Symbol: Sod2/Sod2 Tg(BEST1-rtTA,tetO-cre)1Yzl/?
Background: B6.Cg-Sod2 Tg(BEST1-rtTA,tetO-cre)1Yzl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Heph/Heph Tg(BEST1-cre)1Jdun/?
Background: involves: C57BL/6 * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cryba1/Cryba1 Tg(BEST1-cre)1Jdun/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sod2/Sod2 Tg(BEST1-rtTA,tetO-cre)1Yzl/?
Background: B6J.Cg-Sod2 Tg(BEST1-rtTA,tetO-cre)1Yzl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Rb1cc1/Rb1cc1 Tg(BEST1-cre)1Jdun/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dhdds/Dhdds<+> Tg(BEST1-rtTA,tetO-cre)1Yzl/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dhdds/Dhdds Tg(BEST1-rtTA,tetO-cre)1Yzl/?
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tfam/Tfam Tg(BEST1-cre)1Jdun/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Clic4/Clic4 Tg(BEST1-cre)1Jdun/?
Background: involves: C57BL/6 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tsc1/Tsc1 Tg(BEST1-cre)1Jdun/?
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Lalo U
Year: 2014
Journal: PLoS Biol
Title: Exocytosis of ATP from astrocytes modulates phasic and tonic inhibition in the neocortex.
Volume: 12
Issue: 1
Pages: e1001747
Publication  
First Author: Eblimit A
Year: 2018
Journal: Exp Eye Res
Title: Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice.
Volume: 166
Pages: 120-130
Publication  
First Author: Samra YA
Year: 2021
Journal: Int J Mol Sci
Title: Implication of N-Methyl-d-Aspartate Receptor in Homocysteine-Induced Age-Related Macular Degeneration.
Volume: 22
Issue: 17
Publication  
First Author: Samra YA
Year: 2023
Journal: Int J Mol Sci
Title: Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration.
Volume: 24
Issue: 2
Publication
First Author: Sahu B
Year: 2015
Journal: J Biol Chem
Title: Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.
Volume: 290
Issue: 45
Pages: 27239-47
Publication
First Author: Mao H
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration.
Volume: 55
Issue: 7
Pages: 4613-27
Publication
First Author: Berkowitz BA
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: MRI of Retinal Free Radical Production With Laminar Resolution In Vivo.
Volume: 57
Issue: 2
Pages: 577-85
Publication  
First Author: Zhang Y
Year: 2017
Journal: Mol Vis
Title: Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7.
Volume: 23
Pages: 228-241
Publication  
First Author: DeRamus ML
Year: 2020
Journal: Cells
Title: Selective Ablation of Dehydrodolichyl Diphosphate Synthase in Murine Retinal Pigment Epithelium (RPE) Causes RPE Atrophy and Retinal Degeneration.
Volume: 9
Issue: 3
Publication
First Author: Kurihara T
Year: 2012
Journal: J Clin Invest
Title: Targeted deletion of Vegfa in adult mice induces vision loss.
Volume: 122
Issue: 11
Pages: 4213-7
Publication    
First Author: Kurihara T
Year: 2016
Journal: Elife
Title: Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration.
Volume: 5
Publication
First Author: Han JYS
Year: 2020
Journal: FASEB J
Title: Role of monocarboxylate transporters in regulating metabolic homeostasis in the outer retina: Insight gained from cell-specific Bsg deletion.
Volume: 34
Issue: 4
Pages: 5401-5419
Publication
First Author: Le YZ
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Inducible expression of cre recombinase in the retinal pigmented epithelium.
Volume: 49
Issue: 3
Pages: 1248-53
Publication  
First Author: Fu S
Year: 2014
Journal: Mol Vis
Title: Efficient induction of productive Cre-mediated recombination in retinal pigment epithelium.
Volume: 20
Pages: 480-7
Publication
First Author: Ueki Y
Year: 2009
Journal: Vision Res
Title: Expression of Cre recombinase in retinal Müller cells.
Volume: 49
Issue: 6
Pages: 615-21
Publication  
First Author: Ando S
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Rubicon regulates A2E-induced autophagy impairment in the retinal pigment epithelium implicated in the pathology of age-related macular degeneration.
Volume: 551
Pages: 148-154
Publication
First Author: Perusek L
Year: 2015
Journal: J Biol Chem
Title: Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
Volume: 290
Issue: 48
Pages: 29035-44
Publication  
First Author: DeVera C
Year: 2022
Journal: Int J Mol Sci
Title: The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity.
Volume: 23
Issue: 10
Publication
First Author: Jiang Y
Year: 2022
Journal: Invest Ophthalmol Vis Sci
Title: Dependence of Retinal Pigment Epithelium Integrity on the NRF2-Heme Oxygenase-1 Axis.
Volume: 63
Issue: 9
Pages: 30
Publication
First Author: Patil H
Year: 2014
Journal: J Biol Chem
Title: Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.
Volume: 289
Issue: 43
Pages: 29767-89
Publication  
First Author: Tarchick MJ
Year: 2019
Journal: Exp Eye Res
Title: Endogenous insulin signaling in the RPE contributes to the maintenance of rod photoreceptor function in diabetes.
Volume: 180
Pages: 63-74
Publication
First Author: Holoman NC
Year: 2021
Journal: J Neurosci
Title: Reduction of Glut1 in the Neural Retina But Not the RPE Alleviates Polyol Accumulation and Normalizes Early Characteristics of Diabetic Retinopathy.
Volume: 41
Issue: 14
Pages: 3275-3299
Genotype
Symbol: Cp/Cp Heph/Heph Tg(BEST1-cre)1Jdun/? Tg(Rho-cre)#Yzl/?
Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cp/Cp Heph/Heph Tg(BEST1-cre)1Jdun/?
Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Spata7/Spata7 Tg(BEST1-cre)1Jdun/?
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(BEST1-rtTA,tetO-cre)1Yzl/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(BEST1-cre)1Jdun/?
Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(BEST1-rtTA,tetO-cre)1Yzl/?
Background: involves: 129S6/SvEvTac * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chang B
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: A new mouse model of a late onset retinal degeneration (rd21)
Volume: 56
Issue: 7
Pages: 2881
Publication
First Author: Wolkow N
Year: 2012
Journal: Am J Pathol
Title: Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.
Volume: 180
Issue: 4
Pages: 1614-24
Publication
First Author: Nasonkin IO
Year: 2013
Journal: Development
Title: Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis.
Volume: 140
Issue: 6
Pages: 1330-41
Publication
First Author: Sundermeier TR
Year: 2017
Journal: J Biol Chem
Title: MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice.
Volume: 292
Issue: 8
Pages: 3366-3378
Publication  
First Author: Klee K
Year: 2019
Journal: Exp Eye Res
Title: Systemic knockout of Tspo in mice does not affect retinal morphology, function and susceptibility to degeneration.
Volume: 188
Pages: 107816
Publication  
First Author: Choi EH
Year: 2021
Journal: JCI Insight
Title: An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease.
Volume: 6
Issue: 9
Publication  
First Author: Pyakurel A
Year: 2017
Journal: Mol Cell Biol
Title: Loss of Extracellular Signal-Regulated Kinase 1/2 in the Retinal Pigment Epithelium Leads to RPE65 Decrease and Retinal Degeneration.
Volume: 37
Issue: 24