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Search results 1401 to 1500 out of 1652 for Prnp

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Type Details Score
Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*129V)139Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP)32Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*129M)1Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*D177N*M128V)A21Rchi/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*D177N*M128V)A21Rchi/Tg(Prnp*D177N*M128V)A21Rchi
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/?
Background: C57BL/6-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-ITM2B*)7Jckr/?
Background: C57BL/6-Tg(Prnp-ITM2B*)7Jckr
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-PSEN2*N141I)30Jgr/? Tg(Thy1-APPSwe)71Jgr/?
Background: B6.Cg-Tg(Prnp-PSEN2*N141I)30Jgr Tg(Thy1-APPSwe)71Jgr
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*P101L)2247Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*P101L)2866Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp*P101L)2862Sbp/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)4053Sbp/?
Background: involves: 129S7/SvEvBrd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-MAPT)7Vle/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: involves: 129P2/OlaHsd * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(PRNP)35Jcol/Tg(PRNP)35Jcol
Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(PRNP)45Jcol/Tg(PRNP)45Jcol
Background: involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-UBQLN2)WT-hiHlp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-UBQLN2)WT-lowHlp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-UBQLN2*P506T)#Hlp/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:7571102 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp*D177N*M128V)66Rchi/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Strain
MGI:7571105 | STOCK Prnp<tm1Cwe> Tg(Prnp*D177N*M128V)A21Rchi/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Publication
22383525 | J:241474
First Author: Basak JM
Year: 2012
Journal: J Biol Chem
Title: Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes.
Volume: 287
Issue: 17
Pages: 13959-71
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Allele
Tg(PRNP)1534Gcte | MGI:6193854
Name: transgene insertion 1534, Glenn C Telling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
31329627 | J:277743
First Author: Bender H
Year: 2019
Journal: PLoS One
Title: PrPC knockdown by liposome-siRNA-peptide complexes (LSPCs) prolongs survival and normal behavior of prion-infected mice immunotolerant to treatment.
Volume: 14
Issue: 7
Pages: e0219995
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Publication
16767691 | J:112007
First Author: Sasaki K
Year: 2006
Journal: J Pathol
Title: Clusterin expression in follicular dendritic cells associated with prion protein accumulation.
Volume: 209
Issue: 4
Pages: 484-91
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Publication
23484043 | J:200195
First Author: Wyckoff AC
Year: 2013
Journal: PLoS One
Title: Estimating prion adsorption capacity of soil by BioAssay of Subtracted Infectivity from Complex Solutions (BASICS).
Volume: 8
Issue: 3
Pages: e58630
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Publication
17020952 | J:116053
First Author: Sigurdson CJ
Year: 2006
Journal: J Virol
Title: Strain fidelity of chronic wasting disease upon murine adaptation.
Volume: 80
Issue: 24
Pages: 12303-11
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Publication
20551516 | J:163788
First Author: Sigurdson CJ
Year: 2010
Journal: J Clin Invest
Title: A molecular switch controls interspecies prion disease transmission in mice.
Volume: 120
Issue: 7
Pages: 2590-9
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Publication
36301895 | J:339386
First Author: Race B
Year: 2022
Journal: PLoS One
Title: Microglia have limited influence on early prion pathogenesis, clearance, or replication.
Volume: 17
Issue: 10
Pages: e0276850
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Publication
32454127 | J:292711
 
First Author: Callender JA
Year: 2020
Journal: Neurobiol Dis
Title: Prion protein post-translational modifications modulate heparan sulfate binding and limit aggregate size in prion disease.
Volume: 142
Pages: 104955
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Publication
19478942 | J:148835
First Author: Karapetyan YE
Year: 2009
Journal: PLoS One
Title: Prion strain discrimination based on rapid in vivo amplification and analysis by the cell panel assay.
Volume: 4
Issue: 5
Pages: e5730
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Publication
23871665 | J:201911
First Author: Kong Q
Year: 2013
Journal: Cell Rep
Title: Thermodynamic stabilization of the folded domain of prion protein inhibits prion infection in vivo.
Volume: 4
Issue: 2
Pages: 248-54
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Publication
22811520 | J:187893
First Author: Saá P
Year: 2012
Journal: J Virol
Title: Strain-specific role of RNAs in prion replication.
Volume: 86
Issue: 19
Pages: 10494-504
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Publication
31513666 | J:279503
First Author: Hornemann S
Year: 2019
Journal: PLoS One
Title: Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads.
Volume: 14
Issue: 9
Pages: e0216013
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Allele
Tg(Prnp/PRNP*ARR)FM16Pcg | MGI:5779528
Name: transgene insertion FM16, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:7571103 | B6.Cg-Prnp<tm1Cwe> Tg(Prnp*)A3Dah/Cnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Allele
Tg(Prnp/PRNP*ARR)FF8Pcg | MGI:5779525
Name: transgene insertion FF8, Peter Griffiths
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:5908858 | B6.Cg-Tg(tetO/Prnp-MAPT*K280)530Tli/J
Attribute String: transgenic, mutant strain, congenic
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Publication
25484285 | J:219296
 
First Author: Hanson JE
Year: 2015
Journal: Neurobiol Dis
Title: Altered GluN2B NMDA receptor function and synaptic plasticity during early pathology in the PS2APP mouse model of Alzheimer's disease.
Volume: 74
Pages: 254-62
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Publication
22805202 | J:218149
First Author: Kipanyula MJ
Year: 2012
Journal: Aging Cell
Title: Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.
Volume: 11
Issue: 5
Pages: 885-93
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Publication
19066434 | J:154969
First Author: Ozmen L
Year: 2009
Journal: Neurodegener Dis
Title: Expression of transgenic APP mRNA is the key determinant for beta-amyloid deposition in PS2APP transgenic mice.
Volume: 6
Issue: 1-2
Pages: 29-36
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Publication
15618403 | J:95891
First Author: Chiesa R
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.
Volume: 102
Issue: 1
Pages: 238-43
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Allele
Tg(Prnp/PRNP*ARR)FM18Pcg | MGI:5779521
Name: trangene insertion FM18, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(PRNP)1536Gcte | MGI:6193853
Name: transgene insertion 1536, Glenn C Telling
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*P101L)174Sbp | MGI:5487544
Name: transgene insertion 174, Stanley B Prusiner
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Pcp2-Prnp)E330Zbz | MGI:5014494
Name: transgene insertion E330, Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*6OR)K6M6Pcg | MGI:5775412
Name: transgene insertion K6M6, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)C15Cwe | MGI:2446644
Name: transgene insertion C15, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*)CDah | MGI:5563233
Name: transgene insertion C, David A Harris
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-PRNP*6OR)K6M16Pcg | MGI:5775417
Name: transgene insertion K6M16, Peter Griffiths
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp)E11Cwe | MGI:2446646
Name: transgene insertion E11, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3801181 | B6.Cg-Tg(Prnp-Abca1)EHol/J
Attribute String: transgenic, congenic
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Strain
MGI:2652558 | B6;129S7-Prnp<tm1Cwe> Tg(Prnp)d11Cwe/CweCnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Allele
Tg(Prnp)C4Cwe | MGI:2446641
Name: transgene insertion C4, Charles Weissmann
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnd/Prnp/Prnd
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnd/Prnp/Prnd
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)c35Cwe/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)37Jcol/?
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp)46Jcol/?
Background: involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*129V)144Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp-PRNP*)1Tkit/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-Abca1)EHol/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*D177N*M128V)A21Rchi/Tg(Prnp*D177N*M128V)A21Rchi
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*D177N*M128V)A21Rchi/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp)a20Cwe/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*P101L)2866Sbp/?
Background: involves: 129S7/SvEvBrd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prnp/Prnp Tg(Prnp*P101L)2866Sbp/Tg(Prnp*P101L)2866Sbp
Background: involves: 129S7/SvEvBrd * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Prnp-MAPT*P301L)#Ruvi/Tg(Prnp-MAPT*P301L)#Ruvi
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
8179598 | J:18018
First Author: Kuramoto T
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Tremor and zitter, causative mutant genes for epilepsy with spongiform encephalopathy in spontaneously epileptic rat (SER), are tightly linked to synaptobrevin-2 and prion protein genes, respectively.
Volume: 200
Issue: 2
Pages: 1161-8
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Publication
12039056 | J:75994
First Author: Essalmani R
Year: 2002
Journal: Gene
Title: Sequence determination and expression of the ovine doppel-encoding gene in transgenic mice.
Volume: 285
Issue: 1-2
Pages: 287-90
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Publication
12427847 | J:80186
First Author: Choi DS
Year: 2002
Journal: J Neurosci
Title: Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice.
Volume: 22
Issue: 22
Pages: 9905-11
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Publication
35431893 | J:323890
 
First Author: Blume T
Year: 2022
Journal: Front Aging Neurosci
Title: Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
Volume: 14
Pages: 854031
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Publication
- | J:303205
     
First Author: Magusali N
Year: 2021
Journal: bioRxiv
Title: Genetic variability associated with OAS1 expression in myeloid cells increases the risk of Alzheimer's disease and severe COVID-19 outcomes.
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Publication
34522221 | J:324397
First Author: Biechele G
Year: 2021
Journal: Theranostics
Title: Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
Volume: 11
Issue: 18
Pages: 8964-8976
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Allele
Tg(Prnp-ITM2B/APP695*42)A12Emcg | MGI:3710689
Name: transgene insertion A12, Eileen McGowan
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:4843187 | B6.Cg-Tg(Prnp-tTA)F959Sbp Tg(TetO-Nfkbia*S32A*S36A)1Wcg/Mmmh
Attribute String: transgenic, mutant strain, congenic
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Publication
16980629 | J:112973
First Author: O'Mahony A
Year: 2006
Journal: Mol Cell Biol
Title: NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity.
Volume: 26
Issue: 19
Pages: 7283-98
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Allele
Tg(Eno2-Prnp)#Aag | MGI:5013941
Name: transgene insertion, Adriano Aguzzi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4941865 | B6;129S7-Prnp<tm1Cwe> Tg(Prnp)a20Cwe/CweOrl
Attribute String: targeted mutation, transgenic
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Strain
MGI:2652546 | B6;129S7-Prnp<tm1Cwe> Tg(Prnp)a20Cwe/CweCnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Publication
17964667 | J:128939
First Author: Heikenwalder M
Year: 2007
Journal: J Neuroimmunol
Title: Germinal center B cells are dispensable in prion transport and neuroinvasion.
Volume: 192
Issue: 1-2
Pages: 113-23
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Strain
MGI:4452513 | B6.Cg-Tg(Prnp-ITM2B*)6Jckr Tg(Thy1-APP)3Somm
Attribute String: transgenic, mutant strain, congenic
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Allele
Tg(Pcp2-Prnp)F332Zbz | MGI:5014403
Name: transgene insertion F332, Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
14523101 | J:88193
First Author: Richards JG
Year: 2003
Journal: J Neurosci
Title: PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.
Volume: 23
Issue: 26
Pages: 8989-9003
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Publication
20615468 | J:165986
First Author: Poirier R
Year: 2010
Journal: Neurobiol Dis
Title: Enhanced dentate gyrus synaptic plasticity but reduced neurogenesis in a mouse model of amyloidosis.
Volume: 40
Issue: 2
Pages: 386-93
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Publication
22927427 | J:190030
First Author: Castellano JM
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.
Volume: 109
Issue: 38
Pages: 15502-7
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Strain
MGI:2652544 | B6;129S7-Prnp<tm1Cwe> Tg(Prnp)a19Cwe/CweCnrm
Attribute String: mutant stock, targeted mutation, transgenic
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Allele
Tg(Prnp)23Olds | MGI:6766457
Name: transgene insertion 23, Michael Oldstone
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp*D177N*M128V)G1Rchi | MGI:5614760
Name: transgene insertion G1, Roberto Chiesa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5779526 | FVB/N-Tg(Prnp/PRNP*ARR)FF8Pcg/H
Attribute String: transgenic, mutant strain, coisogenic
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Publication
17475803 | J:121331
First Author: Millecamps S
Year: 2007
Journal: J Neurosci
Title: Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments.
Volume: 27
Issue: 18
Pages: 4947-56
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Strain
MGI:5779522 | STOCK Tg(Prnp/PRNP*ARR)FM18Pcg/H
Attribute String: transgenic, mutant stock
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Allele
Tg(Prnp*M128*D177N)FFI-10Rchi | MGI:5803982
Name: transgene insertion FFI-10, Roberto Chiesa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
23418567 | J:197198
First Author: Garringer HJ
Year: 2013
Journal: PLoS One
Title: Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Volume: 8
Issue: 2
Pages: e56426
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Allele
Tg(Prnp*M128*D177N)FFI-26Rchi | MGI:7564285
Name: transgene insertion FFI-26, Roberto Chiesa
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
1980379 | J:127373
First Author: Hsiao KK
Year: 1990
Journal: Science
Title: Spontaneous neurodegeneration in transgenic mice with mutant prion protein.
Volume: 250
Issue: 4987
Pages: 1587-90
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Strain
MGI:5775415 | STOCK Tg(Prnp-PRNP*6OR)K6M6Pcg/H
Attribute String: transgenic, mutant strain, coisogenic
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Allele
Tg(Prnp-PRNP)340Jmto | MGI:5803821
Name: transgene insertion 340, Juan Maria Torres
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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