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Search results 901 to 1000 out of 1002 for Lhx3

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Type Details Score
Publication
First Author: Zou M
Year: 2015
Journal: Dev Dyn
Title: Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.
Volume: 244
Issue: 1
Pages: 86-97
Publication
First Author: Jung H
Year: 2010
Journal: Neuron
Title: Global control of motor neuron topography mediated by the repressive actions of a single hox gene.
Volume: 67
Issue: 5
Pages: 781-96
Publication    
First Author: Sawai A
Year: 2022
Journal: Elife
Title: PRC1 sustains the integrity of neural fate in the absence of PRC2 function.
Volume: 11
Publication
First Author: Bando H
Year: 2023
Journal: Hum Mol Genet
Title: Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man.
Volume: 32
Issue: 3
Pages: 367-385
Publication
First Author: Lanctot AA
Year: 2013
Journal: Dev Cell
Title: Spatially dependent dynamic MAPK modulation by the Nde1-Lis1-Brap complex patterns mammalian CNS.
Volume: 25
Issue: 3
Pages: 241-55
Publication
First Author: Trowe MO
Year: 2013
Journal: Development
Title: Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis.
Volume: 140
Issue: 11
Pages: 2299-309
Publication
First Author: Hunter CS
Year: 2013
Journal: Diabetes
Title: Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.
Volume: 62
Issue: 3
Pages: 875-86
Publication
First Author: Choi JH
Year: 2018
Journal: Nat Commun
Title: mTORC1 accelerates retinal development via the immunoproteasome.
Volume: 9
Issue: 1
Pages: 2502
Publication
First Author: Rousso DL
Year: 2016
Journal: Cell Rep
Title: Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.
Volume: 15
Issue: 9
Pages: 1930-44
Publication
First Author: Hanley O
Year: 2016
Journal: Neuron
Title: Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns.
Volume: 91
Issue: 5
Pages: 1005-1020
Publication    
First Author: Catela C
Year: 2022
Journal: Elife
Title: Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.
Volume: 11
Publication
First Author: Carreno G
Year: 2017
Journal: Development
Title: Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors.
Volume: 144
Issue: 18
Pages: 3289-3302
Publication
First Author: Gu Z
Year: 2015
Journal: PLoS One
Title: Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.
Volume: 10
Issue: 3
Pages: e0121550
Publication
First Author: Chung YC
Year: 2011
Journal: Gene Expr Patterns
Title: Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.
Volume: 11
Issue: 1-2
Pages: 84-92
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
Publication
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Thaler JP
Year: 2002
Journal: Cell
Title: LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactions.
Volume: 110
Issue: 2
Pages: 237-49
Publication
First Author: Granger A
Year: 2006
Journal: Mol Endocrinol
Title: The LIM-homeodomain proteins Isl-1 and Lhx3 act with steroidogenic factor 1 to enhance gonadotrope-specific activity of the gonadotropin-releasing hormone receptor gene promoter.
Volume: 20
Issue: 9
Pages: 2093-108
GXD Expression  
Probe: MGI:5014495
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3579421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7488699
Age: embryonic day 13.5
Note: Coexpressed with Lhx3 in a subset of cells (medial half) in the medial motor column.
Specimen Label: 5B/C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1551025
Assay Type: RNA in situ
Annotation Date: 2012-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5431896
Age: embryonic day 11.5
Image: 3D
Note: Expression was detected in the rostral tip of Rathke's pouch. At E11.5 expression partially overlaps with Lhx3 and Isl1.
Specimen Label: 3D
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5014495
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3579421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7488699
Age: embryonic day 13.5
Note: Coexpressed with Lhx3 in a subset of cells (medial half) in the medial motor column, similar as in the heterozygous.
Specimen Label: 5E/F
Detected: true
Specimen Num: 2
Allele
Name: transgene insertion, Simon J Rhodes
Allele Type: Transgenic
Attribute String: Recombinase
Genotype
Symbol: Isl2/Isl2<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
MP Term
Genotype
Symbol: Isl2/Isl2<+> Tg(Mnx1-GFP)1Slp/?
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
CL Term
Publication
First Author: Sharma K
Year: 2000
Journal: Nature
Title: Genetic and epigenetic mechanisms contribute to motor neuron pathfinding.
Volume: 406
Issue: 6795
Pages: 515-9
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(LHX3-cre)#Sjr/?
Background: involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Gadd MS
Year: 2013
Journal: J Biol Chem
Title: A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
Volume: 288
Issue: 30
Pages: 21924-35
Protein Domain
Type: Domain
Description: LIM-homeodomain (LIM-HD) proteins are transcription factors that are critical in the development of many cell types and tissues. The activity of LIM-HD proteins is dependent on the essential cofactor LIM domain-binding protein 1 (Ldb1). This entry represents a 30-residue LIM interaction domain (LID) that binds to the LIM domains of all LIM-HD and closely related LIM-only (LMO) proteins. Isl1 (Insulin gene enhancer protein 1) and Isl2 each contain a LID-like sequence in their C-terminal regions, the Lhx3-binding domain (LBD), which binds the LIM domains Lhx3 and Lhx4 [].
Allele
Name: visual system homeobox 2; targeted mutation 2.1, Kamal Sharma
Allele Type: Targeted
Attribute String: Inserted expressed sequence
Allele  
Name: neurogenin 2; targeted mutation 1.1, Michael E Greenberg
Allele Type: Targeted
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(LHX3-cre)#Sjr/?
Background: involves: 129X1/SvJ * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Allele
Name: oligodendrocyte transcription factor 2; targeted mutation 1, David H Rowitch
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: sonic hedgehog; targeted mutation 1, Pao-Tien Chuang
Allele Type: Targeted
Genotype
Symbol: Neurog2/Neurog2
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(LHX3-cre)#Sjr/?
Background: involves: 129S4/SvJaeSor * C3H
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Yamashita T
Year: 1997
Journal: Genomics
Title: Lhx4, a LIM homeobox gene.
Volume: 44
Issue: 1
Pages: 144-6
Allele
Name: achaete-scute family bHLH transcription factor 1; targeted mutation 1, Francois Guillemot
Allele Type: Targeted
Attribute String: Inserted expressed sequence, Null/knockout
Allele
Name: ring finger protein 220; endonuclease-mediated mutation 1, Cheol-Hee Kim
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: NK6 homeobox 1; targeted mutation 1, John L Rubenstein
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Shh/Shh
Background: involves: 129P2/OlaHsd * FVB/N * various
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Olig2/Olig2
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ascl1/Ascl1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Olig1/Olig1 Olig2/Olig2
Background: involves: 129 * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Vsx2/Vsx2<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Nkx6-1/Nkx6-1
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Dong X
Year: 2020
Journal: Cell Rep
Title: LIM-Homeodomain Transcription Factor LHX4 Is Required for the Differentiation of Retinal Rod Bipolar Cells and OFF-Cone Bipolar Subtypes.
Volume: 32
Issue: 11
Pages: 108144
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: zinc finger, C4H2 domain containing; endonuclease-mediated mutation 1.1, Yu-qiang Ding
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: hedgehog acyltransferase; targeted mutation 1, Pao-Tien Chuang
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: hedgehog acyltransferase; targeted mutation 2, Pao-Tien Chuang
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Gli2/Gli2 Gli3/Gli3
Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * Swiss Webster
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Rnf220/Rnf220
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Zc4h2/Zc4h2
Background: involves: C57BL/6 * FVB
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Boëda B
Year: 2011
Journal: J Biol Chem
Title: Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
Volume: 286
Issue: 13
Pages: 11543-54
Publication
First Author: Gage PJ
Year: 1997
Journal: Hum Mol Genet
Title: Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation.
Volume: 6
Issue: 3
Pages: 457-64
Publication
First Author: Elshatory Y
Year: 2007
Journal: J Neurosci
Title: Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cells.
Volume: 27
Issue: 46
Pages: 12707-20
Publication
First Author: Meier BC
Year: 1999
Journal: Mol Cell Endocrinol
Title: Characterization of the porcine Lhx3/LIM-3/P-Lim LIM homeodomain transcription factor.
Volume: 147
Issue: 1-2
Pages: 65-74
Publication
First Author: Kawamata N
Year: 2002
Journal: Oncogene
Title: A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4.
Volume: 21
Issue: 32
Pages: 4983-91
Publication
First Author: Schang AL
Year: 2013
Journal: Neuroendocrinology
Title: Identification and analysis of two novel sites of rat GnRH receptor gene promoter activity: the pineal gland and retina.
Volume: 97
Issue: 2
Pages: 115-31
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 371  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Genotype
Symbol: Hhat/Hhat
Background: involves: 129P2/OlaHsd * FVB/N * various
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Hhat/Hhat
Background: involves: 129P2/OlaHsd * FVB/N * various
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1 Jup/Jup Olig2/Olig2<+>
Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 373  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: achaete-scute family bHLH transcription factor 1; targeted mutation 1, David J Anderson
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Ascl1/Ascl1
Background: involves: 129
Zygosity: hm
Has Mutant Allele: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory