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Search results 101 to 200 out of 279 for Nr1i3

0.062s
Type Details Score
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691627
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777821
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754921
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754927
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697427
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2021-03-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3152723
Stage: TS23
Assay Id: MGI:6513475
Age: embryonic day 15.5
Specimen Label: Table S1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665921
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665927
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716821
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619321
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Note: The tissue was inner ear and ear structures.
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619327
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Note: The tissue was inner ear and ear structures.
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753621
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753627
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778727
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754421
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Widespread
Stage: TS23
Assay Id: MGI:5288653
Age: embryonic day 15.5
Image: 1 & Table S1 - E15.5
Note: Expression is universal.
Specimen Label: 1 & Table S1 - E15.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666821
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4844759
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:4848617
Age: embryonic day 10.5
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647021
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647027
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3508700
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1
Specimen Num: 1
GXD Expression  
Probe: MGI:3505983
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3508701
Age: embryonic day 10.5
Image: 2
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 2
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647018
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3508700
Age: embryonic day 10.5
Image: 2
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 2
Specimen Num: 2
GXD Expression  
Probe: MGI:3505983
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647016
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:3508701
Age: embryonic day 10.5
Image: 1
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3185821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Note: Expression was low or absent.
Specimen Label: 1
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3185827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Note: Expression was low or absent.
Specimen Label: 2
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1876827
Pattern: Widespread
Stage: TS27
Assay Id: MGI:5288653
Age: postnatal day 1
Image: 1 & Table S1 - P0
Note: Expression is universal.
Specimen Label: 1 & Table S1 - P0
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2011-10-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1876828
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5288653
Age: postnatal day 30
Image: 1 & Table S1 - P30
Note: Expression is universal.
Specimen Label: 1 & Table S1 - P30
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754021
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3507479
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3507479
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:3505982
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539062
Age: embryonic day 15.5
Image: GUDMAP:5244
Specimen Label: GUDMAP:5244
Detected: true
Specimen Num: 1
Publication      
First Author: Negishi M
Year: 2004
Journal: Personal Communication
Title: CAR Knockout construct
Publication
First Author: Choi HS
Year: 1996
Journal: J Steroid Biochem Mol Biol
Title: A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily.
Volume: 56
Issue: 1-6 Spec No
Pages: 23-30
Publication
First Author: Hosseinpour F
Year: 2007
Journal: FEBS Lett
Title: Overexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver.
Volume: 581
Issue: 25
Pages: 4937-42
Publication
First Author: Kamino H
Year: 2011
Journal: Int J Oncol
Title: Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors.
Volume: 38
Issue: 6
Pages: 1511-20
Publication
First Author: Hori T
Year: 2018
Journal: Mol Cancer Res
Title: Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver.
Volume: 16
Issue: 8
Pages: 1309-1318
Publication
First Author: Kamino H
Year: 2011
Journal: Cancer Genet
Title: Role of a novel CAR-induced gene, TUBA8, in hepatocellular carcinoma cell lines.
Volume: 204
Issue: 7
Pages: 382-91
Publication
First Author: Seol W
Year: 1996
Journal: Science
Title: An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors.
Volume: 272
Issue: 5266
Pages: 1336-9
Publication
First Author: Scheer N
Year: 2008
Journal: J Clin Invest
Title: A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response.
Volume: 118
Issue: 9
Pages: 3228-39
Publication
First Author: Ross J
Year: 2010
Journal: Toxicol Sci
Title: Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
Volume: 116
Issue: 2
Pages: 452-66
Publication
First Author: Wahlang B
Year: 2016
Journal: Toxicol Sci
Title: Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis.
Volume: 149
Issue: 2
Pages: 396-410
Publication
First Author: Luisier R
Year: 2014
Journal: Toxicol Sci
Title: Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
Volume: 139
Issue: 2
Pages: 501-11
Publication
First Author: Stedman CA
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
Volume: 102
Issue: 6
Pages: 2063-8
Publication
First Author: Breuker C
Year: 2010
Journal: Endocrinology
Title: Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
Volume: 151
Issue: 4
Pages: 1653-61
Publication  
First Author: Zhao LY
Year: 2017
Journal: Biochem Pharmacol
Title: Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression.
Volume: 142
Pages: 194-203
Publication
First Author: Zhai Y
Year: 2007
Journal: Mol Endocrinol
Title: Activation of pregnane X receptor disrupts glucocorticoid and mineralocorticoid homeostasis.
Volume: 21
Issue: 1
Pages: 138-47
Publication
First Author: Saito K
Year: 2013
Journal: Toxicol Sci
Title: Nuclear receptor CAR specifically activates the two-pore K+ channel Kcnk1 gene in male mouse livers, which attenuates phenobarbital-induced hepatic hyperplasia.
Volume: 132
Issue: 1
Pages: 151-61
Publication
First Author: Yamazaki Y
Year: 2011
Journal: Lab Invest
Title: Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver.
Volume: 91
Issue: 11
Pages: 1624-33
Publication
First Author: Saini SP
Year: 2004
Journal: Mol Pharmacol
Title: A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.
Volume: 65
Issue: 2
Pages: 292-300
Publication
First Author: Uppal H
Year: 2005
Journal: Hepatology
Title: Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.
Volume: 41
Issue: 1
Pages: 168-76
Publication
First Author: Niu B
Year: 2018
Journal: Nucleic Acids Res
Title: In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets.
Volume: 46
Issue: 16
Pages: 8385-8403
Publication
First Author: Maglich JM
Year: 2009
Journal: J Lipid Res
Title: The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.
Volume: 50
Issue: 3
Pages: 439-45
Publication
First Author: Chen S
Year: 2012
Journal: Hepatology
Title: Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice.
Volume: 56
Issue: 2
Pages: 658-67
Publication
First Author: Crosby M
Year: 2019
Journal: Drug Metab Dispos
Title: Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice.
Volume: 47
Issue: 3
Pages: 279-282
Publication  
First Author: Skoda J
Year: 2022
Journal: Biochem Pharmacol
Title: Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice.
Volume: 197
Pages: 114905
Publication
First Author: Hasegawa M
Year: 2011
Journal: Mol Pharmacol
Title: Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line.
Volume: 80
Issue: 3
Pages: 518-28
Publication
First Author: Braeuning A
Year: 2014
Journal: Toxicol Sci
Title: Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR.
Volume: 140
Issue: 2
Pages: 259-70
Publication
First Author: MacLeod AK
Year: 2015
Journal: Cancer Res
Title: Activation status of the pregnane X receptor influences vemurafenib availability in humanized mouse models.
Volume: 75
Issue: 21
Pages: 4573-81
Publication  
First Author: Martinot E
Year: 2017
Journal: Sci Rep
Title: Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.
Volume: 7
Pages: 42182
Publication
First Author: Wright E
Year: 2011
Journal: Structure
Title: Helix 11 dynamics is critical for constitutive androstane receptor activity.
Volume: 19
Issue: 1
Pages: 37-44
Publication
First Author: Handschin C
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR).
Volume: 97
Issue: 20
Pages: 10769-74
Publication
First Author: Mäkinen J
Year: 2003
Journal: Biochem J
Title: Dual action of oestrogens on the mouse constitutive androstane receptor.
Volume: 376
Issue: Pt 2
Pages: 465-72
Publication
First Author: Zhang J
Year: 2004
Journal: J Biol Chem
Title: The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
Volume: 279
Issue: 47
Pages: 49517-22
Publication
First Author: Xia J
Year: 2005
Journal: J Biol Chem
Title: Structural determinants of constitutive androstane receptor required for its glucocorticoid receptor interacting protein-1-mediated nuclear accumulation.
Volume: 280
Issue: 8
Pages: 7285-93
Publication
First Author: Lempiäinen H
Year: 2005
Journal: Mol Endocrinol
Title: Antagonist- and inverse agonist-driven interactions of the vitamin D receptor and the constitutive androstane receptor with corepressor protein.
Volume: 19
Issue: 9
Pages: 2258-72
Publication
First Author: Cui JY
Year: 2016
Journal: Biochim Biophys Acta
Title: RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
Volume: 1859
Issue: 9
Pages: 1198-217
Publication
First Author: Yi M
Year: 2020
Journal: Sci Rep
Title: Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver.
Volume: 10
Issue: 1
Pages: 5001
Publication  
First Author: Dong B
Year: 2015
Journal: Nat Commun
Title: Activating CAR and β-catenin induces uncontrolled liver growth and tumorigenesis.
Volume: 6
Pages: 5944
Publication
First Author: Yamamoto Y
Year: 2010
Journal: PLoS One
Title: Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B.
Volume: 5
Issue: 4
Pages: e10121
Publication
First Author: Finn RD
Year: 2009
Journal: Biochem J
Title: Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway.
Volume: 417
Issue: 1
Pages: 43-54
Publication
First Author: Kodama S
Year: 2004
Journal: Mol Cell Biol
Title: Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes.
Volume: 24
Issue: 18
Pages: 7931-40
Publication
First Author: Kuwata K
Year: 2017
Journal: Toxicol Pathol
Title: β-catenin Mutations Are Not Involved in Early-stage Hepatocarcinogenesis Induced by Protoporphyrinogen Oxidase Inhibitors in Mice.
Volume: 45
Issue: 4
Pages: 493-505
Publication
First Author: Scheer N
Year: 2015
Journal: Drug Metab Dispos
Title: Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model.
Volume: 43
Issue: 11
Pages: 1679-90
Publication
First Author: Ohno M
Year: 2014
Journal: PLoS One
Title: The roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse livers.
Volume: 9
Issue: 12
Pages: e115663
Publication
First Author: Assem M
Year: 2004
Journal: J Biol Chem
Title: Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice.
Volume: 279
Issue: 21
Pages: 22250-7
Publication
First Author: Dong B
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.
Volume: 106
Issue: 44
Pages: 18831-6
Publication
First Author: Park YJ
Year: 2012
Journal: Toxicol Appl Pharmacol
Title: Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
Volume: 263
Issue: 2
Pages: 131-7
Publication
First Author: Shizu R
Year: 2013
Journal: PLoS One
Title: Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
Volume: 8
Issue: 4
Pages: e61802
Publication
First Author: Guo GL
Year: 2003
Journal: J Biol Chem
Title: Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.
Volume: 278
Issue: 46
Pages: 45062-71