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Search results 1 to 100 out of 159 for Sesn2

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0.067s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Xu WN
Year: 2023
Journal: Int J Biol Sci
Title: Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration.
Volume: 19
Issue: 2
Pages: 571-592
Publication
First Author: Heidler J
Year: 2013
Journal: Dis Model Mech
Title: Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.
Volume: 6
Issue: 6
Pages: 1378-87
Publication  
First Author: Oh SY
Year: 2021
Journal: Front Cell Dev Biol
Title: Sestrin2 Regulates Osteoclastogenesis via the p62-TRAF6 Interaction.
Volume: 9
Pages: 646803
Publication
First Author: Kallenborn-Gerhardt W
Year: 2013
Journal: Antioxid Redox Signal
Title: Antioxidant activity of sestrin 2 controls neuropathic pain after peripheral nerve injury.
Volume: 19
Issue: 17
Pages: 2013-23
Publication
First Author: Hwang HJ
Year: 2017
Journal: Biochim Biophys Acta
Title: Knockdown of sestrin2 increases pro-inflammatory reactions and ER stress in the endothelium via an AMPK dependent mechanism.
Volume: 1863
Issue: 6
Pages: 1436-1444
Publication  
First Author: Zhang C
Year: 2017
Journal: Neuroscience
Title: Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea.
Volume: 361
Pages: 179-191
Publication
First Author: Li JY
Year: 2021
Journal: Cell Death Dis
Title: Sestrin2 protects dendrite cells against ferroptosis induced by sepsis.
Volume: 12
Issue: 9
Pages: 834
Publication  
First Author: Quan N
Year: 2018
Journal: J Mol Cell Cardiol
Title: Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1α pathway.
Volume: 115
Pages: 170-178
Publication  
First Author: Ro SH
Year: 2016
Journal: Elife
Title: Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.
Volume: 5
Pages: e12204
Publication
First Author: Wempe F
Year: 2010
Journal: Dis Model Mech
Title: Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD.
Volume: 3
Issue: 3-4
Pages: 246-53
Publication
First Author: Lee JH
Year: 2012
Journal: Cell Metab
Title: Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.
Volume: 16
Issue: 3
Pages: 311-21
Publication
First Author: Papadia S
Year: 2008
Journal: Nat Neurosci
Title: Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Volume: 11
Issue: 4
Pages: 476-87
Publication
First Author: Quan N
Year: 2017
Journal: FASEB J
Title: Sestrin2 prevents age-related intolerance to ischemia and reperfusion injury by modulating substrate metabolism.
Volume: 31
Issue: 9
Pages: 4153-4167
Publication
First Author: Li H
Year: 2017
Journal: Exp Cell Res
Title: Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes.
Volume: 354
Issue: 1
Pages: 18-24
Publication  
First Author: Tomasovic A
Year: 2017
Journal: Matrix Biol
Title: Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.
Volume: 59
Pages: 109-120
Publication
First Author: Bae SH
Year: 2013
Journal: Cell Metab
Title: Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage.
Volume: 17
Issue: 1
Pages: 73-84
Publication
First Author: Ding B
Year: 2019
Journal: Oncotarget
Title: p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis.
Volume: 10
Issue: 65
Pages: 6997-7009
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Han D
Year: 2022
Journal: Exp Mol Med
Title: Sestrin2 protects against cholestatic liver injury by inhibiting endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis.
Volume: 54
Issue: 3
Pages: 239-251
Publication
First Author: Park MJ
Year: 2022
Journal: Endocrinol Metab (Seoul)
Title: Sestrin2 Regulates Beneficial β3-Adrenergic Receptor-Mediated Effects Observed in Inguinal White Adipose Tissue and Soleus Muscle.
Volume: 37
Issue: 3
Pages: 552-557
Publication
First Author: Sun X
Year: 2020
Journal: Diabetes
Title: Empagliflozin Ameliorates Obesity-Related Cardiac Dysfunction by Regulating Sestrin2-Mediated AMPK-mTOR Signaling and Redox Homeostasis in High-Fat Diet-Induced Obese Mice.
Volume: 69
Issue: 6
Pages: 1292-1305
Publication  
First Author: Machado IF
Year: 2021
Journal: Int J Mol Sci
Title: miR-378a-3p Participates in Metformin's Mechanism of Action on C2C12 Cells under Hyperglycemia.
Volume: 22
Issue: 2
Publication
First Author: Song S
Year: 2022
Journal: Cell Death Dis
Title: Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Volume: 13
Issue: 7
Pages: 663
GXD Expression      
Probe: MGI:5295236
Assay Type: RT-PCR
Annotation Date: 2011-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5295622
Age: embryonic day 10.5
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569289
Assay Type: RT-PCR
Annotation Date: 2023-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7569298
Age: embryonic day 10.5
Specimen Label: Mdm2+/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7569289
Assay Type: RT-PCR
Annotation Date: 2023-12-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7569298
Age: embryonic day 10.5
Specimen Label: Mdm2-/-
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944965
Age: embryonic day 11.5
Image: g00405 E11.5
Specimen Label: g00405 E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Note: Expression was region specific and scattered.
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697419
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944965
Age: embryonic day 11.5
Image: g00405 E11.5
Specimen Label: g00405 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Note: Expression was region specific and scattered.
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Note: Expression was region specific and scattered.
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Note: Expression was region specific and scattered.
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4944965
Age: embryonic day 11.5
Image: g00405 E11.5
Specimen Label: g00405 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Note: Expression was region specific and scattered.
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4944965
Age: embryonic day 15.5
Image: g00405 E15.5
Specimen Label: g00405 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4886247
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4944965
Age: postnatal day 7
Image: g00405 P7
Note: Expression was region specific and scattered.
Specimen Label: g00405 P7
Detected: true
Specimen Num: 3
Publication
First Author: Lee JH
Year: 2013
Journal: Cell Metab
Title: Sestrins orchestrate cellular metabolism to attenuate aging.
Volume: 18
Issue: 6
Pages: 792-801
Publication
First Author: Li R
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Cardioprotective roles of sestrin 1 and sestrin 2 against doxorubicin cardiotoxicity.
Volume: 317
Issue: 1
Pages: H39-H48
Publication
First Author: Lee JH
Year: 2010
Journal: Science
Title: Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.
Volume: 327
Issue: 5970
Pages: 1223-8
Publication
First Author: Cangelosi AL
Year: 2022
Journal: Science
Title: Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine.
Volume: 377
Issue: 6601
Pages: 47-56
Publication  
First Author: Park HW
Year: 2014
Journal: Nat Commun
Title: Hepatoprotective role of Sestrin2 against chronic ER stress.
Volume: 5
Pages: 4233
Publication  
First Author: Kim JS
Year: 2015
Journal: Sci Rep
Title: Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.
Volume: 5
Pages: 9502
Publication
First Author: Lee JS
Year: 2020
Journal: Exp Mol Med
Title: Sestrin2 inhibits YAP activation and negatively regulates corneal epithelial cell proliferation.
Volume: 52
Issue: 6
Pages: 951-962
Publication
First Author: Essler S
Year: 2009
Journal: FEBS Lett
Title: Role of sestrin2 in peroxide signaling in macrophages.
Volume: 583
Issue: 21
Pages: 3531-5
Publication
First Author: Peng M
Year: 2014
Journal: Cell
Title: Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.
Volume: 159
Issue: 1
Pages: 122-133
Publication
First Author: Tao R
Year: 2015
Journal: Diabetes
Title: Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.
Volume: 64
Issue: 4
Pages: 1211-23
Publication
First Author: Kim M
Year: 2020
Journal: Nat Commun
Title: Sestrins are evolutionarily conserved mediators of exercise benefits.
Volume: 11
Issue: 1
Pages: 190
Publication
First Author: Ro SH
Year: 2014
Journal: FEBS J
Title: Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1.
Volume: 281
Issue: 17
Pages: 3816-27
Publication
First Author: Deng W
Year: 2016
Journal: J Clin Invest
Title: p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing.
Volume: 126
Issue: 8
Pages: 2941-54
Publication
First Author: Morrison A
Year: 2015
Journal: FASEB J
Title: Sestrin2 promotes LKB1-mediated AMPK activation in the ischemic heart.
Volume: 29
Issue: 2
Pages: 408-17
Publication
First Author: Forsberg K
Year: 2013
Journal: J Neurosci
Title: The tumor suppressor p53 fine-tunes reactive oxygen species levels and neurogenesis via PI3 kinase signaling.
Volume: 33
Issue: 36
Pages: 14318-30
Publication
First Author: Budanov AV
Year: 2008
Journal: Cell
Title: p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.
Volume: 134
Issue: 3
Pages: 451-60
Publication
First Author: Kowalsky AH
Year: 2020
Journal: J Biol Chem
Title: The GATOR2-mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation.
Volume: 295
Issue: 7
Pages: 1769-1780
Publication
First Author: Zhu S
Year: 2022
Journal: Circulation
Title: Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.
Volume: 146
Issue: 13
Pages: 1028-1031
Publication
First Author: Petri A
Year: 2006
Journal: J Mol Endocrinol
Title: The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice.
Volume: 37
Issue: 2
Pages: 301-16
Publication
First Author: Meechan DW
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome.
Volume: 106
Issue: 38
Pages: 16434-45
Publication  
First Author: Mirra S
Year: 2021
Journal: Neurobiol Dis
Title: CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.
Volume: 156
Pages: 105405