|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 321 for Crp

0.043s
Type Details Score
Publication
First Author: Ko MS
Year: 1994
Journal: Mamm Genome
Title: Genetic mapping of 40 cDNA clones on the mouse genome by PCR.
Volume: 5
Issue: 6
Pages: 349-55
Publication
First Author: Hearne CM
Year: 1991
Journal: Mamm Genome
Title: Additional microsatellite markers for mouse genome mapping.
Volume: 1
Issue: 4
Pages: 273-82
Publication
First Author: Warden CH
Year: 1993
Journal: Genomics
Title: Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.
Volume: 18
Issue: 2
Pages: 295-307
Publication
First Author: Welch CL
Year: 1996
Journal: J Lipid Res
Title: Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.
Volume: 37
Issue: 7
Pages: 1406-21
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
MP Term
Publication
First Author: Fan Z
Year: 2019
Journal: Biochim Biophys Acta Gene Regul Mech
Title: An interaction between MKL1, BRG1, and C/EBPβ mediates palmitate induced CRP transcription in hepatocytes.
Volume: 1862
Issue: 9
Pages: 194412
Publication
First Author: Pearce AC
Year: 2002
Journal: Blood
Title: Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.
Volume: 100
Issue: 10
Pages: 3561-9
Publication
First Author: Cameron AD
Year: 2008
Journal: J Mol Biol
Title: CRP binding and transcription activation at CRP-S sites.
Volume: 383
Issue: 2
Pages: 313-23
Protein
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
Interaction Experiment
Description: A nutrient-sensitive interaction between Sirt1 and HNF-1 regulates Crp expression.
MP Term
Publication
First Author: Cameron AD
Year: 2006
Journal: Nucleic Acids Res
Title: Non-canonical CRP sites control competence regulons in Escherichia coli and many other gamma-proteobacteria.
Volume: 34
Issue: 20
Pages: 6001-14
MP Term
Publication
First Author: Szalai AJ
Year: 2014
Journal: Trans R Soc Trop Med Hyg
Title: Deletion of C-reactive protein ameliorates experimental cerebral malaria?
Volume: 108
Issue: 9
Pages: 591-3
Publication
First Author: Szalai AJ
Year: 1996
Journal: Infect Immun
Title: Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae.
Volume: 64
Issue: 11
Pages: 4850-3
Publication
First Author: Bai G
Year: 2011
Journal: Mol Microbiol
Title: Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.
Volume: 82
Issue: 1
Pages: 180-98
Allele
Name: C-reactive protein, pentraxin-related; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Szalai AJ
Year: 2002
Journal: J Immunol
Title: Experimental allergic encephalomyelitis is inhibited in transgenic mice expressing human C-reactive protein.
Volume: 168
Issue: 11
Pages: 5792-7
Publication
First Author: Pegues MA
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: C-reactive protein exacerbates renal ischemia-reperfusion injury.
Volume: 304
Issue: 11
Pages: F1358-65
Publication
First Author: Wang D
Year: 2005
Journal: Arterioscler Thromb Vasc Biol
Title: Estrogen treatment abrogates neointima formation in human C-reactive protein transgenic mice.
Volume: 25
Issue: 10
Pages: 2094-9
Publication
First Author: Grad E
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity after vascular injury.
Volume: 293
Issue: 1
Pages: H489-95
Publication
First Author: Zhang L
Year: 2015
Journal: J Immunol
Title: C-reactive protein directly suppresses Th1 cell differentiation and alleviates experimental autoimmune encephalomyelitis.
Volume: 194
Issue: 11
Pages: 5243-52
Publication
First Author: Morrison MC
Year: 2017
Journal: Sci Rep
Title: Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?
Volume: 7
Issue: 1
Pages: 2915
Publication
First Author: Kozijn AE
Year: 2019
Journal: Osteoarthritis Cartilage
Title: Human C-reactive protein aggravates osteoarthritis development in mice on a high-fat diet.
Volume: 27
Issue: 1
Pages: 118-128
Publication
First Author: Szalai AJ
Year: 1995
Journal: J Immunol
Title: Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice.
Volume: 155
Issue: 5
Pages: 2557-63
Publication
First Author: Ji Y
Year: 2014
Journal: J Thromb Haemost
Title: C-reactive protein induces expression of tissue factor and plasminogen activator inhibitor-1 and promotes fibrin accumulation in vein grafts.
Volume: 12
Issue: 10
Pages: 1667-77
Publication
First Author: Szalai AJ
Year: 2003
Journal: Arthritis Rheum
Title: Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene.
Volume: 48
Issue: 6
Pages: 1602-11
Publication
First Author: Buchet A
Year: 1999
Journal: Mol Microbiol
Title: Positive co-regulation of the Escherichia coli carnitine pathway cai and fix operons by CRP and the CaiF activator.
Volume: 34
Issue: 3
Pages: 562-75
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Allele
Name: trasngene insertion, Ulrich Ruther
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Kleemann R
Year: 2004
Journal: Blood
Title: Evidence for anti-inflammatory activity of statins and PPARalpha activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro.
Volume: 103
Issue: 11
Pages: 4188-94
Publication
First Author: You YK
Year: 2021
Journal: Int J Biol Sci
Title: Deletion of Smad3 protects against C-reactive protein-induced renal fibrosis and inflammation in obstructive nephropathy.
Volume: 17
Issue: 14
Pages: 3911-3922
Publication
First Author: Szalai AJ
Year: 1998
Journal: J Immunol
Title: Testosterone and IL-6 requirements for human C-reactive protein gene expression in transgenic mice.
Volume: 160
Issue: 11
Pages: 5294-9
Publication
First Author: Hirschfield GM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice.
Volume: 102
Issue: 23
Pages: 8309-14
Publication
First Author: Paul A
Year: 2004
Journal: Circulation
Title: C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.
Volume: 109
Issue: 5
Pages: 647-55
Publication
First Author: Torzewski M
Year: 2008
Journal: Thromb Haemost
Title: No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice.
Volume: 99
Issue: 1
Pages: 196-201
Publication
First Author: Grad E
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Role of thromboxane receptor in C-reactive protein-induced thrombosis.
Volume: 32
Issue: 10
Pages: 2468-74
Publication
First Author: Hage FG
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: C-reactive protein-mediated vascular injury requires complement.
Volume: 30
Issue: 6
Pages: 1189-95
Publication
First Author: Trion A
Year: 2005
Journal: Arterioscler Thromb Vasc Biol
Title: No effect of C-reactive protein on early atherosclerosis development in apolipoprotein E*3-leiden/human C-reactive protein transgenic mice.
Volume: 25
Issue: 8
Pages: 1635-40
Publication
First Author: Klein L
Year: 1998
Journal: J Exp Med
Title: CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium.
Volume: 188
Issue: 1
Pages: 5-16
Publication
First Author: Sinha S
Year: 2012
Journal: PLoS One
Title: Natural DNA uptake by Escherichia coli.
Volume: 7
Issue: 4
Pages: e35620
Protein Domain
Type: Domain
Description: This entry represents the N-terminal domain of TfoX from Haemophilus influenzae. TfoX Positively regulates genes required for DNA transformation (late competence-specific genes) in association with CRP []. This domain can also be found in Sxy from Escherichia coli. Sxy induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation [, ].
Publication
First Author: Szalai AJ
Year: 2000
Journal: J Immunol
Title: Complement-dependent acute-phase expression of C-reactive protein and serum amyloid P-component.
Volume: 165
Issue: 2
Pages: 1030-5
Publication  
First Author: Weinhold B
Year: 1997
Journal: Biochem J
Title: Interleukin-6-dependent and -independent regulation of the human C-reactive protein gene.
Volume: 327 ( Pt 2)
Pages: 425-9
Publication  
First Author: Weinhold B
Year: 1997
Journal: Biochem J
Title: Interleukin-6 is necessary, but not sufficient, for induction of the humanC-reactive protein gene in vivo.
Volume: 325 ( Pt 3)
Pages: 617-21
Publication
First Author: Klein TC
Year: 1995
Journal: Eur J Immunol
Title: Tolerance and immunity to the inducible self antigen C-reactive protein in transgenic mice.
Volume: 25
Issue: 12
Pages: 3489-95
Publication
First Author: Devos A
Year: 1995
Journal: Cytogenet Cell Genet
Title: The genes coding for rat cystatin-related prostate protein (Cstrp) map to chromosome 3q41.
Volume: 68
Issue: 3-4
Pages: 239-42
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Allele
Name: transgene insertion 2, Laurent Baud
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Laurent Baud
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Henderson JR
Year: 2002
Journal: J Histochem Cytochem
Title: Expression of the gene encoding the LIM protein CRP2: a developmental profile.
Volume: 50
Issue: 1
Pages: 107-11
Publication
First Author: Kim Y
Year: 2014
Journal: FEBS Lett
Title: C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expression.
Volume: 588
Issue: 4
Pages: 625-31
Publication
First Author: Morrison M
Year: 2014
Journal: Atherosclerosis
Title: Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo.
Volume: 233
Issue: 1
Pages: 149-56
Strain
Attribute String: transgenic, mutant strain, coisogenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Bottazzi B
Year: 2016
Journal: J Hepatol
Title: The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling.
Volume: 64
Issue: 6
Pages: 1416-27
Protein Domain
Type: Domain
Description: The Crp-type HTH domain is a DNA-binding, winged helix-turn-helix (wHTH) domain of about 70-75 amino acids present in transcription regulators of the crp-fnr family, involved in the control of virulence factors, enzymes of aromatic ring degradation, nitrogen fixation, photosynthesis, and varioustypes of respiration. The Crp-Fnr family is named after the first members identified in Escherichia coli: the well characterised cyclic AMP receptor protein CRP or CAP (catabolite activator protein) and the fumarate and nitrate reductase regulator Fnr. Crp-type HTH domain proteins occur in most bacteria and in chloroplasts of red algae. The DNA-binding HTH domain is located in the C-terminal part; the N-terminal part of the proteins of the Crp-Fnr family contains a nucleotide-binding domain and a dimerization/linker helix occurs in between. The Crp-Fnr regulators predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals, such as cAMP, anoxia, redox state, oxidative and nitrosative stress, carbon monoxide, nitric oxide or temperature [, ].
Protein Domain
Type: Family
Description: Pentraxin-related protein PTX3 is a long pentraxin that provides defence against infectious agents and plays several functions in tissue repair and regulation of cancer-related inflammation [].Pentraxins are a family of evolutionarily conserved molecules with regulatory role in inflammation. They share the "pentraxin signature"(His-x-Cys-x-Ser/Thr-Trp-x-Ser, where x is any amino acid) and can be divided into a short and a long arm based on their structural organization. Short pentraxins, feature a peculiar quaternary structure with five or ten identical protomer subunits arranged into symmetric pentamers, such as CRP and SAP, are secreted proteins produced by hepatocytes in response to IL-6. Long pentraxins, on the other end, display an unrelated amino-terminal region coupled to a C-terminal pentraxin domain. PTX3 is the prototype of the long pentraxin subfamily produced by myeloid and stromal cells, but not by hepatocytes, in response to primary pro-inflammatory cytokines or microbial moieties [].
Publication
First Author: Liang C
Year: 2019
Journal: Nat Commun
Title: HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis.
Volume: 10
Issue: 1
Pages: 4579
Publication
First Author: Gardner J
Year: 2012
Journal: Biochem Biophys Res Commun
Title: G-protein-coupled receptor GPR21 knockout mice display improved glucose tolerance and increased insulin response.
Volume: 418
Issue: 1
Pages: 1-5
Publication  
First Author: Yang J
Year: 2017
Journal: Sci Signal
Title: C-reactive protein promotes bone destruction in human myeloma through the CD32-p38 MAPK-Twist axis.
Volume: 10
Issue: 509
Publication
First Author: Fiorillo MT
Year: 1992
Journal: Eur J Immunol
Title: Expression of the murine interleukin 6 receptor in hepatoma cells: the intracytoplasmic domain is not required for interleukin 6 signal transduction.
Volume: 22
Issue: 3
Pages: 799-804
Publication
First Author: Wang X
Year: 1992
Journal: J Biol Chem
Title: Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc.
Volume: 267
Issue: 13
Pages: 9176-84
Publication
First Author: Bretz JD
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: C/EBP-related protein 2 confers lipopolysaccharide-inducible expression of interleukin 6 and monocyte chemoattractant protein 1 to a lymphoblastic cell line.
Volume: 91
Issue: 15
Pages: 7306-10
Publication
First Author: Walsh MT
Year: 1996
Journal: Immunogenetics
Title: Fine mapping of the human pentraxin gene region on chromosome 1q23.
Volume: 44
Issue: 1
Pages: 62-9
Publication
First Author: Weiskirchen R
Year: 1995
Journal: J Biol Chem
Title: The cysteine-rich protein family of highly related LIM domain proteins.
Volume: 270
Issue: 48
Pages: 28946-54
Publication  
First Author: Pepys MB
Year: 1983
Journal: Adv Immunol
Title: Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein.
Volume: 34
Pages: 141-212
Publication
First Author: Reid MS
Year: 1994
Journal: J Biol Chem
Title: Apexin, an acrosomal pentaxin.
Volume: 269
Issue: 51
Pages: 32615-20
Publication  
First Author: Doni A
Year: 2019
Journal: Front Immunol
Title: The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer.
Volume: 10
Pages: 712
Publication
First Author: Irvine AS
Year: 1993
Journal: Nucleic Acids Res
Title: Lactobacillus casei contains a member of the CRP-FNR family.
Volume: 21
Issue: 3
Pages: 753
Publication
First Author: Omeis IA
Year: 1996
Journal: Genomics
Title: Mouse and human neuronal pentraxin 1 (NPTX1): conservation, genomic structure, and chromosomal localization.
Volume: 36
Issue: 3
Pages: 543-5
Publication
First Author: Li XA
Year: 1998
Journal: Biochem Biophys Res Commun
Title: Serum amyloid P component associates with high density lipoprotein as well as very low density lipoprotein but not with low density lipoprotein.
Volume: 244
Issue: 1
Pages: 249-52
Publication
First Author: Romero IR
Year: 1998
Journal: Clin Immunol Immunopathol
Title: Inflammatory potential of C-reactive protein complexes compared to immune complexes.
Volume: 87
Issue: 2
Pages: 155-62
Publication
First Author: Emsley J
Year: 1994
Journal: Nature
Title: Structure of pentameric human serum amyloid P component.
Volume: 367
Issue: 6461
Pages: 338-45