|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 400 out of 465 for Pik3cd

<< First    < Previous  |  Next >    Last >>
0.049s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_10
Specimen Label: euxassay_012716_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_11
Specimen Label: euxassay_012716_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_12
Specimen Label: euxassay_012716_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_13
Specimen Label: euxassay_012716_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_14
Specimen Label: euxassay_012716_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_15
Specimen Label: euxassay_012716_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_16
Specimen Label: euxassay_012716_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_17
Specimen Label: euxassay_012716_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_18
Specimen Label: euxassay_012716_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_19
Specimen Label: euxassay_012716_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827207
Age: embryonic day 14.5
Image: euxassay_012716_20
Specimen Label: euxassay_012716_20
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5001923
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542477
Age: embryonic day 15.5
Image: GUDMAP:10980
Specimen Label: GUDMAP:10980
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422279
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: ES2288; Specimen S889
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4425091
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422279
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: ES2288; Specimen S889
Detected: false
Specimen Num: 1
•
•
•
•
•
Publication
12774123 | J:83823
First Author: Takahashi K
Year: 2003
Journal: Nature
Title: Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.
Volume: 423
Issue: 6939
Pages: 541-5
•
•
•
•
•
Publication
25875604 | J:307462
First Author: Onyilagha C
Year: 2015
Journal: PLoS Negl Trop Dis
Title: The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice.
Volume: 9
Issue: 4
Pages: e0003716
•
•
•
•
•
Publication
14751923 | J:90540
First Author: Puri KD
Year: 2004
Journal: Blood
Title: Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.
Volume: 103
Issue: 9
Pages: 3448-56
•
•
•
•
•
Publication
35742807 | J:326265
 
First Author: Manda-Handzlik A
Year: 2022
Journal: Int J Mol Sci
Title: Lack of Functional P110δ Affects Expression of Activation Marker CD80 but Does Not Influence Functions of Neutrophils.
Volume: 23
Issue: 12
•
•
•
•
•
Publication
27843137 | J:241805
First Author: Carter MJ
Year: 2017
Journal: Leukemia
Title: PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.
Volume: 31
Issue: 6
Pages: 1423-1433
•
•
•
•
•
Publication
12235209 | J:79133
First Author: Clayton E
Year: 2002
Journal: J Exp Med
Title: A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation.
Volume: 196
Issue: 6
Pages: 753-63
•
•
•
•
•
Publication
16116162 | J:113237
First Author: Webb LM
Year: 2005
Journal: J Immunol
Title: Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.
Volume: 175
Issue: 5
Pages: 2783-7
•
•
•
•
•
Publication
18259608 | J:135309
First Author: Jarmin SJ
Year: 2008
Journal: J Clin Invest
Title: T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice.
Volume: 118
Issue: 3
Pages: 1154-64
•
•
•
•
•
Publication
19297623 | J:147569
First Author: Saudemont A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease.
Volume: 106
Issue: 14
Pages: 5795-800
•
•
•
•
•
Publication
24919154 | J:213482
First Author: Ali K
Year: 2014
Journal: Nature
Title: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.
Volume: 510
Issue: 7505
Pages: 407-411
•
•
•
•
•
Publication
17082571 | J:140501
First Author: Patton DT
Year: 2006
Journal: J Immunol
Title: Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells.
Volume: 177
Issue: 10
Pages: 6598-602
•
•
•
•
•
Publication
18250464 | J:131982
First Author: Ali K
Year: 2008
Journal: J Immunol
Title: Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo.
Volume: 180
Issue: 4
Pages: 2538-44
•
•
•
•
•
Publication
15739165 | J:97803
First Author: Thomas MJ
Year: 2005
Journal: Eur J Immunol
Title: Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases.
Volume: 35
Issue: 4
Pages: 1283-91
•
•
•
•
•
Publication
22586681 | J:193070
First Author: Fruman DA
Year: 2011
Journal: Cancer Discov
Title: PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic.
Volume: 1
Issue: 7
Pages: 562-72
•
•
•
•
•
Publication
17626838 | J:143141
First Author: Ji H
Year: 2007
Journal: Blood
Title: Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation.
Volume: 110
Issue: 8
Pages: 2940-7
•
•
•
•
•
Publication
16011964 | J:114310
First Author: Senis YA
Year: 2005
Journal: Platelets
Title: Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets.
Volume: 16
Issue: 3-4
Pages: 191-202
•
•
•
•
•
Publication
19596993 | J:151583
First Author: Liu D
Year: 2009
Journal: J Immunol
Title: The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.
Volume: 183
Issue: 3
Pages: 1921-33
•
•
•
•
•
Publication
31216371 | J:280464
First Author: Hao L
Year: 2019
Journal: J Leukoc Biol
Title: Critical role for PI3Kγ-dependent neutrophil reactive oxygen species in WKYMVm-induced microvascular hyperpermeability.
Volume: 106
Issue: 5
Pages: 1117-1127
•
•
•
•
•
Publication
24009720 | J:206413
First Author: Zotes TM
Year: 2013
Journal: PLoS One
Title: PI3K p110δ is expressed by gp38(-)CD31(+) and gp38(+)CD31(+) spleen stromal cells and regulates their CCL19, CCL21, and LTβR mRNA levels.
Volume: 8
Issue: 8
Pages: e72960
•
•
•
•
•
Publication
18684865 | J:142153
First Author: Zebedin E
Year: 2008
Journal: Blood
Title: Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance.
Volume: 112
Issue: 12
Pages: 4655-64
•
•
•
•
•
Publication
12446777 | J:80614
First Author: Jou ST
Year: 2002
Journal: Mol Cell Biol
Title: Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.
Volume: 22
Issue: 24
Pages: 8580-91
•
•
•
•
•
Publication
20200404 | J:162269
First Author: Beer-Hammer S
Year: 2010
Journal: J Leukoc Biol
Title: The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.
Volume: 87
Issue: 6
Pages: 1083-95
•
•
•
•
•
Publication
17723215 | J:124330
First Author: Tassi I
Year: 2007
Journal: Immunity
Title: p110gamma and p110delta phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells.
Volume: 27
Issue: 2
Pages: 214-27
•
•
•
•
•
Publication
27442134 | J:282980
First Author: Mothes B
Year: 2016
Journal: PLoS One
Title: p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.
Volume: 11
Issue: 7
Pages: e0159310
•
•
•
•
•
Publication
17277100 | J:144002
First Author: Llorian M
Year: 2007
Journal: J Immunol
Title: The PI3K p110delta is required for down-regulation of RAG expression in immature B cells.
Volume: 178
Issue: 4
Pages: 1981-5
•
•
•
•
•
Publication
18412166 | J:134324
First Author: Randis TM
Year: 2008
Journal: Eur J Immunol
Title: Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils.
Volume: 38
Issue: 5
Pages: 1215-24
•
•
•
•
•
Publication
16114097 | J:113491
First Author: Glassford J
Year: 2005
Journal: Eur J Immunol
Title: Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.
Volume: 35
Issue: 9
Pages: 2748-61
•
•
•
•
•
Publication
16304053 | J:125791
First Author: Swat W
Year: 2006
Journal: Blood
Title: Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival.
Volume: 107
Issue: 6
Pages: 2415-22
•
•
•
•
•
Publication
17644738 | J:149123
First Author: Kim N
Year: 2007
Journal: Blood
Title: The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion.
Volume: 110
Issue: 9
Pages: 3202-8
•
•
•
•
•
Publication
21390257 | J:171724
First Author: Patton DT
Year: 2011
Journal: PLoS One
Title: The PI3K p110δ regulates expression of CD38 on regulatory T cells.
Volume: 6
Issue: 3
Pages: e17359
•
•
•
•
•
Publication
27859053 | J:246248
First Author: Jayachandran N
Year: 2017
Journal: Eur J Immunol
Title: B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.
Volume: 47
Issue: 2
Pages: 280-290
•
•
•
•
•
Publication
21487106 | J:185999
First Author: Kulkarni S
Year: 2011
Journal: Sci Signal
Title: PI3Kβ plays a critical role in neutrophil activation by immune complexes.
Volume: 4
Issue: 168
Pages: ra23
•
•
•
•
•
Publication
19451552 | J:150750
First Author: Gollmer K
Year: 2009
Journal: Blood
Title: CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.
Volume: 114
Issue: 3
Pages: 580-8
•
•
•
•
•
Publication
24043760 | J:204070
First Author: Soler A
Year: 2013
Journal: J Exp Med
Title: Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
Volume: 210
Issue: 10
Pages: 1937-45
•
•
•
•
•
Publication
31120863 | J:336308
 
First Author: Hemmati S
Year: 2019
Journal: JCI Insight
Title: PI3 kinase alpha and delta promote hematopoietic stem cell activation.
Volume: 5
Issue: 13
•
•
•
•
•
Publication
15769890 | J:107472
First Author: Puri KD
Year: 2005
Journal: Blood
Title: The role of endothelial PI3Kgamma activity in neutrophil trafficking.
Volume: 106
Issue: 1
Pages: 150-7
•
•
•
•
•
Publication
17632516 | J:123408
First Author: Wang HB
Year: 2007
Journal: Nat Immunol
Title: P-selectin primes leukocyte integrin activation during inflammation.
Volume: 8
Issue: 8
Pages: 882-92
•
•
•
•
•
Publication
26740009 | J:339385
First Author: Garçon F
Year: 2016
Journal: Immunol Cell Biol
Title: PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.
Volume: 94
Issue: 5
Pages: 486-95
•
•
•
•
•
Publication
27531651 | J:259189
First Author: Houslay DM
Year: 2016
Journal: Sci Signal
Title: Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.
Volume: 9
Issue: 441
Pages: ra82
•
•
•
•
•
Publication
23024273 | J:190607
First Author: Roller A
Year: 2012
Journal: J Immunol
Title: Blockade of phosphatidylinositol 3-kinase PI3Kδ or PI3Kγ reduces IL-17 and ameliorates imiquimod-induced psoriasis-like dermatitis.
Volume: 189
Issue: 9
Pages: 4612-20
•
•
•
•
•
Publication
22422878 | J:184069
First Author: Zhang TT
Year: 2012
Journal: J Immunol
Title: p110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression.
Volume: 188
Issue: 8
Pages: 3700-8
•
•
•
•
•
Publication
18786920 | J:143388
First Author: Konrad S
Year: 2008
Journal: J Biol Chem
Title: Phosphoinositide 3-kinases gamma and delta, linkers of coordinate C5a receptor-Fcgamma receptor activation and immune complex-induced inflammation.
Volume: 283
Issue: 48
Pages: 33296-303
•
•
•
•
•
Publication
15834429 | J:98315
First Author: Jackson SP
Year: 2005
Journal: Nat Med
Title: PI 3-kinase p110beta: a new target for antithrombotic therapy.
Volume: 11
Issue: 5
Pages: 507-14
•
•
•
•
•
Publication
9235916 | J:42042
First Author: Chantry D
Year: 1997
Journal: J Biol Chem
Title: p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.
Volume: 272
Issue: 31
Pages: 19236-41
•
•
•
•
•
Publication
15496927 | J:93235
First Author: Ali K
Year: 2004
Journal: Nature
Title: Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.
Volume: 431
Issue: 7011
Pages: 1007-11
•
•
•
•
•
Publication
32414808 | J:291916
First Author: Stark AK
Year: 2020
Journal: J Immunol
Title: Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation.
Volume: 205
Issue: 1
Pages: 78-89
•
•
•
•
•
Publication
20534549 | J:161378
First Author: Foukas LC
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Activity of any class IA PI3K isoform can sustain cell proliferation and survival.
Volume: 107
Issue: 25
Pages: 11381-6
•
•
•
•
•
Publication
24553178 | J:210890
First Author: Goodwin CB
Year: 2014
Journal: Blood
Title: PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML.
Volume: 123
Issue: 18
Pages: 2838-42
•
•
•
•
•
Publication
27270400 | J:244991
First Author: Akula MK
Year: 2016
Journal: Nat Immunol
Title: Control of the innate immune response by the mevalonate pathway.
Volume: 17
Issue: 8
Pages: 922-9
•
•
•
•
•
Publication
30093657 | J:265645
First Author: Stark AK
Year: 2018
Journal: Nat Commun
Title: PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner.
Volume: 9
Issue: 1
Pages: 3174
•
•
•
•
•
Publication
22586351 | J:193072
First Author: Chiao PJ
Year: 2011
Journal: Cancer Discov
Title: Kras, Pten, NF-κB, and inflammation: dangerous liaisons.
Volume: 1
Issue: 2
Pages: 103-5
•
•
•
•
•
Publication
33159421 | J:301545
   
First Author: Iacono A
Year: 2020
Journal: EMBO Rep
Title: Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
Pages: e49756
•
•
•
•
•
Publication
23023391 | J:188561
First Author: Aksoy E
Year: 2012
Journal: Nat Immunol
Title: The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.
Volume: 13
Issue: 11
Pages: 1045-1054
•
•
•
•
•
Publication
17170126 | J:145339
First Author: Kishimoto H
Year: 2007
Journal: Blood
Title: The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells.
Volume: 109
Issue: 8
Pages: 3316-24
•
•
•
•
•
Publication
18006698 | J:130753
First Author: Garçon F
Year: 2008
Journal: Blood
Title: CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.
Volume: 111
Issue: 3
Pages: 1464-71
•
•
•
•
•
Publication
20826752 | J:164283
First Author: Rolf J
Year: 2010
Journal: J Immunol
Title: Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.
Volume: 185
Issue: 7
Pages: 4042-52
•
•
•
•
•
Publication
28190771 | J:251900
First Author: Mauro C
Year: 2017
Journal: Cell Metab
Title: Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.
Volume: 25
Issue: 3
Pages: 593-609
•
•
•
•
•
Publication
25921527 | J:228366
First Author: Gross C
Year: 2015
Journal: Cell Rep
Title: Selective role of the catalytic PI3K subunit p110β in impaired higher order cognition in fragile X syndrome.
Volume: 11
Issue: 5
Pages: 681-8
•
•
•
•
•
Publication
28199309 | J:244529
First Author: Compagno M
Year: 2017
Journal: Nature
Title: Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Volume: 542
Issue: 7642
Pages: 489-493
•
•
•
•
•
Publication
29759484 | J:276193
 
First Author: Zhou T
Year: 2018
Journal: EBioMedicine
Title: Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ.
Volume: 31
Pages: 217-225
•
•
•
•
•
Publication
18391955 | J:134510
First Author: Sinclair LV
Year: 2008
Journal: Nat Immunol
Title: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking.
Volume: 9
Issue: 5
Pages: 513-21
•
•
•
•
•
Publication
23183047 | J:194209
First Author: Finlay DK
Year: 2012
Journal: J Exp Med
Title: PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.
Volume: 209
Issue: 13
Pages: 2441-53
•
•
•
•
•
Publication
29038423 | J:254898
First Author: Uehara M
Year: 2017
Journal: Nat Commun
Title: Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ.
Volume: 8
Issue: 1
Pages: 951
•
•
•
•
•
Publication
19016531 | J:141373
First Author: Henley T
Year: 2008
Journal: Eur J Immunol
Title: B-cell responses to B-cell activation factor of the TNF family (BAFF) are impaired in the absence of PI3K delta.
Volume: 38
Issue: 12
Pages: 3543-8
•
•
•
•
•
Publication
18178811 | J:130950
First Author: Janas ML
Year: 2008
Journal: J Immunol
Title: The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells.
Volume: 180
Issue: 2
Pages: 739-46
•
•
•
•
•
Publication
25503990 | J:240906
First Author: Zheng L
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Inactivation of PI3Kδ induces vascular injury and promotes aneurysm development by upregulating the AP-1/MMP-12 pathway in macrophages.
Volume: 35
Issue: 2
Pages: 368-77
•
•
•
•
•
Publication
21390242 | J:171725
First Author: Liu S
Year: 2011
Journal: PLoS One
Title: The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.
Volume: 6
Issue: 3
Pages: e17161
•
•
•
•
•
Publication
31546615 | J:293658
 
First Author: Oka A
Year: 2019
Journal: Cells
Title: Phosphoinositide 3-Kinase P110δ-Signaling Is Critical for Microbiota-Activated IL-10 Production by B Cells that Regulate Intestinal Inflammation.
Volume: 8
Issue: 10
•
•
•
•
•
Publication
24470500 | J:209825
First Author: Attridge K
Year: 2014
Journal: J Immunol
Title: IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells.
Volume: 192
Issue: 5
Pages: 2195-201
•
•
•
•
•
Publication
19362372 | J:149323
First Author: Dil N
Year: 2009
Journal: Mol Immunol
Title: Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation.
Volume: 46
Issue: 10
Pages: 1970-8
•
•
•
•
•
Publication
23029326 | J:191970
First Author: Juss JK
Year: 2012
Journal: PLoS One
Title: Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survival.
Volume: 7
Issue: 9
Pages: e45933
•
•
•
•
•
Publication
19033389 | J:146084
First Author: Papakonstanti EA
Year: 2008
Journal: J Cell Sci
Title: Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.
Volume: 121
Issue: Pt 24
Pages: 4124-33
•
•
•
•
•
Publication
23499492 | J:195115
First Author: Mattila PK
Year: 2013
Journal: Immunity
Title: The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.
Volume: 38
Issue: 3
Pages: 461-74
•
•
•
•
•
Publication
17673465 | J:125348
First Author: Schoenwaelder SM
Year: 2007
Journal: J Biol Chem
Title: Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets.
Volume: 282
Issue: 39
Pages: 28648-58
•
•
•
•
•
Publication
16625210 | J:109024
First Author: Foukas LC
Year: 2006
Journal: Nature
Title: Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.
Volume: 441
Issue: 7091
Pages: 366-70
•
•
•
•
•
Publication
19940148 | J:159946
First Author: Schoenwaelder SM
Year: 2010
Journal: J Biol Chem
Title: Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces.
Volume: 285
Issue: 4
Pages: 2886-96
•
•
•
•
•
Publication
20699475 | J:185404
First Author: Ramadani F
Year: 2010
Journal: Sci Signal
Title: The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
Volume: 3
Issue: 134
Pages: ra60
•
•
•
•
•
Publication
30930171 | J:275680
First Author: Goossens P
Year: 2019
Journal: Cell Metab
Title: Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.
Volume: 29
Issue: 6
Pages: 1376-1389.e4
•
•
•
•
•
Publication
26442967 | J:227645
 
First Author: Yuzugullu H
Year: 2015
Journal: Nat Commun
Title: A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis.
Volume: 6
Pages: 8501
•
•
•
•
•
Publication
18191593 | J:131150
First Author: Arana E
Year: 2008
Journal: Immunity
Title: Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.
Volume: 28
Issue: 1
Pages: 88-99
•
•
•
•
•
Publication
17618288 | J:123409
First Author: Huntington ND
Year: 2007
Journal: Nat Immunol
Title: Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.
Volume: 8
Issue: 8
Pages: 856-63
•
•
•
•
•
Publication
24357053 | J:229142
First Author: Gayral S
Year: 2014
Journal: Cardiovasc Res
Title: Elastin-derived peptides potentiate atherosclerosis through the immune Neu1-PI3Kγ pathway.
Volume: 102
Issue: 1
Pages: 118-27
•
•
•
•
•
Publication
18755982 | J:143800
First Author: Anderson KE
Year: 2008
Journal: Blood
Title: CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.
Volume: 112
Issue: 13
Pages: 5202-11
•
•
•
•
•
Publication
21295499 | J:168979
First Author: Macintyre AN
Year: 2011
Journal: Immunity
Title: Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism.
Volume: 34
Issue: 2
Pages: 224-36
•
•
•
•
•
Publication
21930962 | J:179460
First Author: Janas ML
Year: 2011
Journal: J Immunol
Title: Interaction of Ras with p110γ is required for thymic β-selection in the mouse.
Volume: 187
Issue: 9
Pages: 4667-75
•
•
•
•
•
Publication
20038597 | J:156822
First Author: Janas ML
Year: 2010
Journal: J Exp Med
Title: Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.
Volume: 207
Issue: 1
Pages: 247-61
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom