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Search results 101 to 123 out of 123 for Tep1

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Type Details Score
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
15701761 | -
First Author: Poderycki MJ
Year: 2005
Journal: Nucleic Acids Res
Title: The p80 homology region of TEP1 is sufficient for its association with the telomerase and vault RNAs, and the vault particle.
Volume: 33
Issue: 3
Pages: 893-902
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Protein Coding Gene
MGI:109583 | Pten
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR008850 | TEP1_N
Type: Repeat
Description: Telomerase protein component 1 (TP1/TLP1) or TEP1 is a protein component of two ribonucleoprotein (RNP) complexes: vaults and telomerase. Vaults are large RNP particles with a barrel-like structure (). The telomerase RNP replenishes incomplete chromosome termini due to DNA replication. Mammalian TEP1 is an RNA-binding protein and is required for the association of vault RNA with the vault particle [, ]. The N-terminal part of TEP1 contains 4 copies of the TEP1 N-terminal repeat in tandem. The repeat is composed of 30 amino acids and occurs in combination with the TROVE () and NACHT () domains and with WD-40 repeats (see ) in the C-terminal part.
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Protein Domain
IPR037214 | TROVE_dom_sf
Type: Homologous_superfamily
Description: The TROVE (Telomerase, Ro and Vault) domain is a module of ~300-500 residues that is found in TEP1 and Ro60 the protein components of three ribonucleoprotein particles. It is also found in bacterial ribonucleoproteins suggesting an ancient origin of these ribonucleoproteins. It can be found associated with other domains, such as the VWFA domain, the TEP1 N-terminal domain, the NACHT-NTPase domain, and WD-40 repeats. This domain may be involved in binding the RNA components of the three RNPs, which are telomerase RNA, Y RNA and vault RNA [].The TROVE domain contains a few absolutely conserved residues. As none of these conserved residues are the polar type of amino acids found in active sites, it seems unlikely that this region has an enzymatic function [].Structurally, the TROVE domain consist of two superhelical sections arranged like a horse-shoe.
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Protein Domain
IPR008858 | TROVE_dom
Type: Domain
Description: The TROVE (Telomerase, Ro and Vault) domain is a module of ~300-500 residues that is found in TEP1 and Ro60 the protein components of three ribonucleoprotein particles. It is also found in bacterial ribonucleoproteins suggesting an ancient origin of these ribonucleoproteins. It can be found associated with other domains, such as the VWFA domain, the TEP1 N-terminal domain, the NACHT-NTPase domain, and WD-40 repeats. This domain may be involved in binding the RNA components of the three RNPs, which are telomerase RNA, Y RNA and vault RNA [].The TROVE domain contains a few absolutely conserved residues. As none of these conserved residues are the polar type of amino acids found in active sites, it seems unlikely that this region has an enzymatic function [].
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Publication
14563212 | -
 
First Author: Bateman A
Year: 2003
Journal: BMC Bioinformatics
Title: The TROVE module: a common element in Telomerase, Ro and Vault ribonucleoproteins.
Volume: 4
Pages: 49
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Protein Domain
IPR045804 | DUF5920
Type: Domain
Description: This entry represents a domain of unknown function found in the Telomerase protein component 1 (TEP1) from in animals. It contains an homology region to the Telomerase associated protein from Tetrahymena p80 [].TEP1 is a component of the telomerase ribonucleoprotein complex and is thought to be responsible for catalysing the addition of new telomeres to chromosomes. TEP1 is also a component of the vault particle, a cytoplasmic ribonucleoprotein complex, in which it is required for vault RNA stability and its association with the vault particle []. This domain is localised between the TROVE () and DUF4062 () domains.
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Protein
O08848
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
A0A2I3BR80
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: true
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Protein
Q8R562
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
Q80W12
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
Q3TJ75
Organism: Mus musculus/domesticus
Length: 538  
Fragment?: false
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Protein
P97499
Organism: Mus musculus/domesticus
Length: 2629  
Fragment?: false
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Protein
Q5XKB2
Organism: Mus musculus/domesticus
Length: 2629  
Fragment?: false
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