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Search results 1301 to 1400 out of 1444 for Pax1

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Type Details Score
Publication
36685938 | J:332918
 
First Author: Cai S
Year: 2022
Journal: Front Genet
Title: Transcriptomic analysis of the upper lip and primary palate development in mice.
Volume: 13
Pages: 1039850
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Publication
32913205 | J:296151
First Author: Liu J
Year: 2020
Journal: Sci Rep
Title: Transcriptional analysis of cleft palate in TGFβ3 mutant mice.
Volume: 10
Issue: 1
Pages: 14940
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Publication
25859222 | J:237754
 
First Author: Maga AM
Year: 2015
Journal: Front Physiol
Title: Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.
Volume: 6
Pages: 92
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Publication
1673105 | J:11120
First Author: Siracusa LD
Year: 1991
Journal: Genetics
Title: Identification and applications of repetitive probes for gene mapping in the mouse.
Volume: 127
Issue: 1
Pages: 169-79
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Publication
19164599 | J:147173
First Author: Sultana DA
Year: 2009
Journal: Blood
Title: Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development.
Volume: 113
Issue: 13
Pages: 2976-87
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Publication
35512705 | J:325251
First Author: Chen A
Year: 2022
Journal: Cell
Title: Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays.
Volume: 185
Issue: 10
Pages: 1777-1792.e21
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Publication
34671097 | J:312414
First Author: Yogosawa S
Year: 2021
Journal: Commun Biol
Title: Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient.
Volume: 4
Issue: 1
Pages: 1204
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
26238476 | J:226028
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
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Publication
24146773 | J:209112
First Author: Shimizu H
Year: 2013
Journal: PLoS One
Title: The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.
Volume: 8
Issue: 10
Pages: e75754
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:15839
       
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
27193062 | J:262503
 
First Author: Adhikari K
Year: 2016
Journal: Nat Commun
Title: A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation.
Volume: 7
Pages: 11616
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GXD Expression
GXD Expression
Probe: MGI:1339568
Assay Type: Immunohistochemistry
Annotation Date: 1999-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3114419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1339566
Age: embryonic day 11.5
Image: 1.P,R
Note: Pax1 and Fkh14 (Mfh1) are coexpressed in sclerotome cells in the ventrolateral region.
Specimen Label: 1.P,R
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:15970
Assay Type: RNA in situ
Annotation Date: 1999-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1721420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:1349752
Age: embryonic day 12.5
Image: 6. F
Note: Expression is detected in the vertebral bodies which are are smaller in Pax1 mutants.
Specimen Label: 6. F
Detected: true
Specimen Num: 9
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Allele
Tg(Rr513-mCherry)#Ndav | MGI:7711940
Name: transgene insertion, Nadav Ahituv
Allele Type: Transgenic
Attribute String: Reporter
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HT Experiment
GSE86112 | RNA-seq study of directed sclerotome, Lon non-coding RNA PEAT, and the embryonic Dll1 lineage form E9.0-9.5
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Pax1<un> | MGI:1856222
 
Name: paired box 1; undulated
Allele Type: Spontaneous
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Allele
Rr513<em1Ndav> | MGI:7711743
Name: regulatory region 513; endonuclease-mediated mutation 1, Nadav Ahituv
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Rr366694<em1Ndav> | MGI:7711741
Name: regulatory region 366694; endonuclease-mediated mutation 1, Nadav Ahituv
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Allele
Del(2Rr366694-Rr513)1Ndav | MGI:7711747
Name: deletion, Chr 2, Nadav Ahituv 1
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
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Strain
MGI:2161048 | STOCK Pax1<un>
Attribute String: mutant stock
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Strain
MGI:3845812 | B6.Cg-Pax1<un>
Attribute String: targeted mutation, congenic
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Allele
Pax1<Un-s> | MGI:1856225
 
Name: paired box 1; undulated short tail
Allele Type: Spontaneous
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Allele
Pax1<un-i> | MGI:3603176
 
Name: paired box 1; undulated intermediate
Allele Type: Spontaneous
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Allele
Pax1<m1Btlr> | MGI:5688488
 
Name: paired box 1; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: B6.Cg-Pax1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr366694/Rr366694
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr513/Rr513
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(2Rr366694-Rr513)1Ndav/Del(2Rr366694-Rr513)1Ndav
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: involves: C3HeB/FeJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:3845979 | B6.CC57BR-Pax1<Un-s>
Attribute String: congenic, spontaneous mutation
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Strain
MGI:5688563 | C57BL/6J-Pax1<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: B6.CC57BR-Pax1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: involves: CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: involves: CC57BR/MvY
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: involves: C57BL/6 * CC57BR/MvY
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: C57BL/6J-Pax1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: involves: C57BL/6 * CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+>
Background: B6.CC57BR-Pax1
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:2165152 | B10.UW(R509)-H3b<b> Pax1<un> a<t>/Dcr
Attribute String: congenic, mutant strain
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Strain
MGI:4843362 | B10.Cg-Tgm3<we> H3<b> Pax1<un>/ChwMmucd
Attribute String: congenic, minor histocompatibility congenic, mutant strain, spontaneous mutation
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Genotype
Genotype
Symbol: Pax1/Pax1 Ph/Ph<+>
Background: involves: C3HeB/FeJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1<+> Etn2/Etn2<+>
Background: involves: C57BL/6 * C57BL/6ByJ * CC57BR/MvY
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: involves: C57BL/6 * CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax1/Pax1
Background: involves: C3HeB/FeJ * C57BL/6 * CC57BR/MvY
Zygosity: ht
Has Mutant Allele: true
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Strain
MGI:2161864 | B6C3Fe a/a-Tgm3<we> Pax1<un> a<t>/J
Attribute String: mutant stock, spontaneous mutation
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Strain
MGI:2161151 | STOCK Tgm3<we> Pax1<un> a<t>
Attribute String: mutant stock, spontaneous mutation
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Genotype
Genotype
Symbol: Pax1/Pax1<+> Tcf3/Tcf3
Background: involves: 129P2/OlaHsd * C3H * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: kkt/kkt<+> Pax1/Pax1<+>
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:2161254 | STOCK + + A<w>/Tgm3<we> Pax1<un> a<t>
Attribute String: mutant stock, spontaneous mutation
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Strain
MGI:2161533 | B10.UW-H3<b> Tgm3<we> Pax1<un> a<t>/SnJ
Attribute String: mutant strain, minor histocompatibility congenic
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Strain
MGI:5650229 | (B10.LP-H13<b> x B10.Cg-Bloc1s6<pa> Tgm3<we> Pax1<un> a<t>)F1
Attribute String: F1 hybrid, mutant stock
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Strain
MGI:2161234 | B10.Cg-Bloc1s6<pa> Tgm3<we> Pax1<un> a<t>
Attribute String: congenic, mutant strain
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Publication
37704733 | J:347266
First Author: Sun J
Year: 2023
Journal: Nature
Title: A vertebral skeletal stem cell lineage driving metastasis.
Volume: 621
Issue: 7979
Pages: 602-609
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Publication
7557441 | J:28816
First Author: Chalepakis G
Year: 1995
Journal: Gene
Title: Identification of DNA recognition sequences for the Pax3 paired domain.
Volume: 162
Issue: 2
Pages: 267-70
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Strain
MGI:3577940 | STOCK In(2)5Rk + + + a<t>/+ Bloc1s6<pa> Tgm3<we> Pax1<un> a<t>/H
Attribute String: chromosome aberration, mutant stock, radiation induced mutation, inversion, spontaneous mutation
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Protein Domain
IPR001523 | Paired_dom
Type: Domain
Description: The paired domain is an approximately 126 amino acid DNA-binding domain, which is found in eukaryotic transcription regulatory proteins involved in embryogenesis. The domain was originally described as the 'paired box' in the Drosophila protein paired (prd) [, ]. The paired domain is generally located in the N-terminal part. An octapeptide []and/or a homeodomain can occur C-terminal to the paired domain, as well as a Pro-Ser-Thr-rich C terminus.Paired domain proteins can function as transcription repressors or activators. The paired domain contains three subdomains, which show functional differences in DNA-binding. The crystal structures of prd and Pax proteins show that the DNA-bound paired domain is bipartite, consisting of an N-terminal subdomain (PAI or NTD) and a C-terminal subdomain (RED or CTD), connected by a linker. PAI and RED each form a three-helical fold, with the most C-terminal helices comprising a helix-turn-helix (HTH) motif that binds the DNA major groove. In addition, the PAI subdomain encompasses an N-terminal β-turn andβ-hairpin, also named 'wing', participating in DNA-binding. The linker canbind into the DNA minor groove. Different Pax proteins and their alternativelyspliced isoforms use different (sub)domains for DNA-binding to mediate thespecificity of sequence recognition [, ].Some proteins known to contain a paired domain:Drosophila paired (prd), a segmentation pair-rule class protein.Drosophila gooseberry proximal (gsb-p) and gooseberry distal (gsb-d),segmentation polarity class proteins.Drosophila Pox-meso and Pox-neuro proteins.The Pax proteins:Mammalian protein Pax1, which may play a role in the formation of segmented structures in the embryo. In mouse, mutations in Pax1 produce the undulated phenotype, characterised by vertebral malformations along the entire rostro-caudal axis.Mammalian protein Pax2, a probable transcription factor that may have arole in kidney cell differentiation.Mammalian protein Pax3. Pax3 is expressed during early neurogenesis. In humans, defects in Pax3 are the cause of Waardenburg's syndrome (WS), anautosomal dominant combination of deafness and pigmentary disturbance.Mammalian protein Pax4 pays an important role in the differentiation and development of pancreatic islet beta cells. It binds to a common element in the glucagon, insulin and somatostatin promoters. In humans, it has been related to the rare, familial, clinically and genetically heterogeneous form of diabetes MODY (maturity-onset diabetes of the young).Mammalian protein Pax5, also known as B-cell specific transcription factor(BSAP). Pax5 is involved in the regulation of the CD19 gene. It plays animportant role in B-cell differentiation as well as neural development andspermatogenesis.Mammalian protein Pax6 (oculorhombin). Pax6 is a transcription factor withimportant functions in eye and nasal development. In Man, defects in Pax6are the cause of aniridia type II (AN2), an autosomal dominant disordercharacterised by complete or partial absence of the iris.Mammalian protein Pax7 is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration.Mammalian protein Pax8, required in thyroid development.Mammalian protein Pax9, required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. In man, defects in Pax9 cause oligodontia.Zebrafish protein Paired box protein Pax-2a, involved in the development of the midbrain/hindbrain boundary organizer and specification of neuronal cell fates.Xenopus laevis protein Paired box protein Pax-3-A, which promotes both hatching gland and neural crest cell fates, two of the cell populations that arise from the neural plate border.
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Publication
10811620 | -
First Author: Eberhard D
Year: 2000
Journal: EMBO J
Title: Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family.
Volume: 19
Issue: 10
Pages: 2292-303
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Protein
Q9EQ02
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: true
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Protein
Q8VDB6
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: false
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Protein
A2A409
Organism: Mus musculus/domesticus
Length: 139  
Fragment?: true
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Protein
G3UY80
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: true
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Protein
Q8VHH9
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: false
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Protein
Q8VBY9
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
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Protein
G3UYK4
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: true
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Protein
Q8VDB4
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
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Protein
Q8VBZ1
Organism: Mus musculus/domesticus
Length: 64  
Fragment?: false
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Publication
2877747 | -
First Author: Bopp D
Year: 1986
Journal: Cell
Title: Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila.
Volume: 47
Issue: 6
Pages: 1033-40
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Publication
3123319 | -
First Author: Baumgartner S
Year: 1987
Journal: Genes Dev
Title: Structure of two genes at the gooseberry locus related to the paired gene and their spatial expression during Drosophila embryogenesis.
Volume: 1
Issue: 10
Pages: 1247-67
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Publication
11103953 | -
First Author: Underhill DA
Year: 2000
Journal: Biochem Cell Biol
Title: Genetic and biochemical diversity in the Pax gene family.
Volume: 78
Issue: 5
Pages: 629-38
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Publication
15148315 | -
First Author: Apuzzo S
Year: 2004
Journal: J Biol Chem
Title: Cross-talk between the paired domain and the homeodomain of Pax3: DNA binding by each domain causes a structural change in the other domain, supporting interdependence for DNA Binding.
Volume: 279
Issue: 32
Pages: 33601-12
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Protein
Q02650
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: false
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