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Search results 101 to 200 out of 388 for Arf1

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Hits by Pathway

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Hits by Category

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542505
Specimen Label: BCM_1542505
Detected: true
Specimen Num: 20
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542509
Specimen Label: BCM_1542509
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542511
Specimen Label: BCM_1542511
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542512
Specimen Label: BCM_1542512
Detected: true
Specimen Num: 27
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542506
Specimen Label: BCM_1542506
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542501
Specimen Label: BCM_1542501
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3271628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542498
Specimen Label: BCM_1542498
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3590528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542498
Specimen Label: BCM_1542498
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_2399545
Specimen Label: BCM_2399545
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542501
Specimen Label: BCM_1542501
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3592628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542508
Specimen Label: BCM_1542508
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3273028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542498
Specimen Label: BCM_1542498
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_2399550
Specimen Label: BCM_2399550
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_1542514
Specimen Label: BCM_1542514
Detected: true
Specimen Num: 29
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5159
Specimen Label: GUDMAP:5159
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_2399548
Specimen Label: BCM_2399548
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_2399546
Specimen Label: BCM_2399546
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_2399547
Specimen Label: BCM_2399547
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000621
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541181
Age: embryonic day 15.5
Image: GUDMAP:5158
Specimen Label: GUDMAP:5158
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693246
Age: postnatal adult
Image: BCM_2399548
Specimen Label: BCM_2399548
Detected: true
Specimen Num: 8
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Publication
24951541 | J:214976
First Author: Bellouze S
Year: 2014
Journal: Hum Mol Genet
Title: Golgi fragmentation in pmn mice is due to a defective ARF1/TBCE cross-talk that coordinates COPI vesicle formation and tubulin polymerization.
Volume: 23
Issue: 22
Pages: 5961-75
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Publication
21447739 | J:171205
First Author: Zeng Y
Year: 2011
Journal: Cancer Res
Title: p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb.
Volume: 71
Issue: 7
Pages: 2781-92
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Publication
25990896 | J:224786
First Author: Carrasco-Garcia E
Year: 2015
Journal: Aging Cell
Title: Increased gene dosage of Ink4/Arf and p53 delays age-associated central nervous system functional decline.
Volume: 14
Issue: 4
Pages: 710-4
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Publication
8947846 | J:42235
First Author: Hosaka M
Year: 1996
Journal: J Biochem
Title: Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6).
Volume: 120
Issue: 4
Pages: 813-9
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Publication
24792215 | J:216094
First Author: Schultz ML
Year: 2014
Journal: PLoS One
Title: CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
Volume: 9
Issue: 5
Pages: e96647
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Publication
23012656 | J:259473
First Author: Yamauchi J
Year: 2012
Journal: Sci Signal
Title: Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development.
Volume: 5
Issue: 243
Pages: ra69
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Publication
8195219 | J:18483
First Author: Schürmann A
Year: 1994
Journal: J Biol Chem
Title: Cloning of two novel ADP-ribosylation factor-like proteins and characterization of their differential expression in 3T3-L1 cells.
Volume: 269
Issue: 22
Pages: 15683-8
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Publication
21187408 | J:169416
First Author: Boone DN
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism.
Volume: 108
Issue: 2
Pages: 632-7
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Publication
11092755 | J:106641
First Author: Hilditch-Maguire P
Year: 2000
Journal: Hum Mol Genet
Title: Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.
Volume: 9
Issue: 19
Pages: 2789-97
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Publication
12466855 | J:80501
First Author: Gitton Y
Year: 2002
Journal: Nature
Title: A gene expression map of human chromosome 21 orthologues in the mouse.
Volume: 420
Issue: 6915
Pages: 586-90
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
10788613 | -
First Author: Dontsova M
Year: 2000
Journal: FEBS Lett
Title: Translation termination factor aRF1 from the archaeon Methanococcus jannaschii is active with eukaryotic ribosomes.
Volume: 472
Issue: 2-3
Pages: 213-6
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Protein Domain
IPR020918 | Peptide_chain-rel_aRF1
Type: Family
Description: Terminating protein synthesis on the ribosome requires the presence of a class I polypeptide chain release factor (RF) to induce peptidyl-tRNA hydrolysis. Bacteria possess two class I RFs; RF1 which recognises UAG and UAA, and RF2 which recognises UGA and UAA. Mitochondrial RFs are related structurally and functionally to those of bacteria. Eukaryotes posses only a single class 1 factor, eRF1, which recognises all three termination codons. Similarly, in all archaeal species where the complete sequence of the genome is available, only a single class I factor, aRF1, has been identified so far. The aRF1 family is highly homologous to the eRF1 family, indicating a common origin and ancestor molecule. The bacterial and mitochondrial class I RFs show no significant sequence similarity with their eukaryotic and archaeal counterparts and are considered to form a separate family. For more information see [, , ].This entry represents the archaeal release factor aRF1, which seems to have functional resemblance to eukaryotic RF1 [].
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Publication
21653832 | J:178045
First Author: Nishida K
Year: 2011
Journal: J Immunol
Title: Gab2, via PI-3K, regulates ARF1 in FcεRI-mediated granule translocation and mast cell degranulation.
Volume: 187
Issue: 2
Pages: 932-41
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Publication
20228810 | J:160637
First Author: Anitei M
Year: 2010
Journal: Nat Cell Biol
Title: Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.
Volume: 12
Issue: 4
Pages: 330-40
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Publication
22573888 | J:197767
First Author: Hasegawa J
Year: 2012
Journal: Mol Biol Cell
Title: ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5.
Volume: 23
Issue: 13
Pages: 2481-9
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Publication
12771146 | J:230354
First Author: Kruljac-Letunic A
Year: 2003
Journal: J Biol Chem
Title: The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1.
Volume: 278
Issue: 32
Pages: 29560-70
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Publication
9179839 | -
First Author: Buckingham RH
Year: 1997
Journal: Mol Microbiol
Title: Polypeptide chain release factors.
Volume: 24
Issue: 3
Pages: 449-56
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Publication
10471834 | -
First Author: Karamyshev AL
Year: 1999
Journal: FEBS Lett
Title: Polypeptide release factor eRF1 from Tetrahymena thermophila: cDNA cloning, purification and complex formation with yeast eRF3.
Volume: 457
Issue: 3
Pages: 483-8
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Publication
15979507 | -
First Author: Donaldson JG
Year: 2005
Journal: Biochim Biophys Acta
Title: Multiple activities for Arf1 at the Golgi complex.
Volume: 1744
Issue: 3
Pages: 364-73
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Interaction Experiment
Zhang J (2013)
Description: Filamin A regulates neuronal migration through brefeldin A-inhibited guanine exchange factor 2-dependent Arf1 activation.
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Publication
26765562 | -
   
First Author: Richardson BC
Year: 2016
Journal: Elife
Title: The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase.
Volume: 5
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Protein Coding Gene
MGI:2183559 | Arfgap1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34830155 | -
 
First Author: Kolakowski D
Year: 2021
Journal: Int J Mol Sci
Title: The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.
Volume: 22
Issue: 22
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Protein
Q9EPJ9
Organism: Mus musculus/domesticus
Length: 414  
Fragment?: false
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Protein
Q9EPJ9-2
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Publication
19669794 | -
First Author: Bui QT
Year: 2009
Journal: Mol Genet Genomics
Title: Large Arf1 guanine nucleotide exchange factors: evolution, domain structure, and roles in membrane trafficking and human disease.
Volume: 282
Issue: 4
Pages: 329-50
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Publication
8861955 | -
First Author: Rosa JL
Year: 1996
Journal: EMBO J
Title: p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteins.
Volume: 15
Issue: 16
Pages: 4262-73
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Publication
16115449 | -
First Author: Dubois T
Year: 2005
Journal: Med Sci (Paris)
Title: [ARHGAP10, a novel RhoGAP at the cross-road between ARF1 and Cdc42 pathways, regulates Arp2/3 complex and actin dynamics on Golgi membranes].
Volume: 21
Issue: 8-9
Pages: 692-4
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Publication
9233772 | -
First Author: Rosa JL
Year: 1997
Journal: Oncogene
Title: A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70.
Volume: 15
Issue: 1
Pages: 1-6
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Protein
Q9QWY8
Organism: Mus musculus/domesticus
Length: 1147  
Fragment?: false
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Protein
Q9QWY8-3
Organism: Mus musculus/domesticus
Length: 1135  
Fragment?: false
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Protein
Q9QWY8-2
Organism: Mus musculus/domesticus
Length: 1090  
Fragment?: false
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Protein
Q9QWY8-4
Organism: Mus musculus/domesticus
Length: 1132  
Fragment?: false
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Publication
16571680 | J:112531
First Author: Natsume W
Year: 2006
Journal: Mol Biol Cell
Title: SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network.
Volume: 17
Issue: 6
Pages: 2592-603
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Protein Domain
IPR031669 | Fn3_2
Type: Domain
Description: This fibronectin type III domain is found in fungal chitin biosynthesis protein CHS5 where, together with the neighbouring BRCT domain (), it binds to the Arf1 GTPase [].
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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