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Search results 101 to 183 out of 183 for Ubr2

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0.028s
Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885812
Specimen Label: UC Davis_1885812
Detected: true
Specimen Num: 40
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885813
Specimen Label: UC Davis_1885813
Detected: true
Specimen Num: 41
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885814
Specimen Label: UC Davis_1885814
Detected: true
Specimen Num: 42
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885815
Specimen Label: UC Davis_1885815
Detected: true
Specimen Num: 43
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691582
Age: postnatal adult
Image: UC Davis_1885817
Note: vesicular gland
Specimen Label: UC Davis_1885817
Detected: true
Specimen Num: 44
Publication  
First Author: Mulugeta Achame E
Year: 2010
Journal: BMC Genomics
Title: The ubiquitin-conjugating enzyme HR6B is required for maintenance of X chromosome silencing in mouse spermatocytes and spermatids.
Volume: 11
Pages: 367
Publication
First Author: Ma Y
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Loss of RAD6B induces degeneration of the cochlea in mice.
Volume: 531
Issue: 3
Pages: 402-408
Publication
First Author: Kwon YT
Year: 2001
Journal: Mol Cell Biol
Title: Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway.
Volume: 21
Issue: 23
Pages: 8007-21
Publication
First Author: Kwon YT
Year: 2000
Journal: Mol Cell Biol
Title: Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway.
Volume: 20
Issue: 11
Pages: 4135-48
Publication
First Author: Kwon YT
Year: 2002
Journal: Science
Title: An essential role of N-terminal arginylation in cardiovascular development.
Volume: 297
Issue: 5578
Pages: 96-9
Publication
First Author: Tasaki T
Year: 2009
Journal: J Biol Chem
Title: The substrate recognition domains of the N-end rule pathway.
Volume: 284
Issue: 3
Pages: 1884-95
Publication
First Author: Piatkov KI
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments.
Volume: 109
Issue: 27
Pages: E1839-47
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Protein
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1558  
Fragment?: false
UniProt Feature
Begin: 2
Description: E3 ubiquitin-protein ligase UBR2
Type: chain
End: 1755
GO Term
Publication
First Author: Kwak KS
Year: 2004
Journal: Cancer Res
Title: Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia.
Volume: 64
Issue: 22
Pages: 8193-8
Publication
First Author: Yin J
Year: 2004
Journal: Hum Mol Genet
Title: RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.
Volume: 13
Issue: 20
Pages: 2421-30
Publication
First Author: Chui AJ
Year: 2019
Journal: Science
Title: N-terminal degradation activates the NLRP1B inflammasome.
Volume: 364
Issue: 6435
Pages: 82-85
Publication
First Author: Tasaki T
Year: 2007
Journal: J Biol Chem
Title: Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems.
Volume: 282
Issue: 25
Pages: 18510-20
HT Experiment
Series Id: GSE18824
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
GO Term
Publication
First Author: Zanet J
Year: 2015
Journal: Science
Title: Pri sORF peptides induce selective proteasome-mediated protein processing.
Volume: 349
Issue: 6254
Pages: 1356-8
Protein Domain
Type: Family
Description: This entry represents a group of E3 ubiquitin-protein ligases, including UBR1, UBR2 and UBR3. They are part of the N-end rule pathway []. They recognize and bind to proteins bearing specific N-terminal residues, leading to their ubiquitination and subsequent degradation [, ].The UBR1 protein was shown to bind specifically to proteins bearing N-terminalresidues that are destabilising according to the N-end rule, but not tootherwise identical proteins bearing stabilising N-terminal residues []. UBR1 contains an N-terminal conserved region (the UBR-type zinc finger) which is also found in various proteins implicated in N-degron recognition [].
Publication
First Author: Sin TK
Year: 2019
Journal: Cancer Res
Title: p300 Mediates Muscle Wasting in Lewis Lung Carcinoma.
Volume: 79
Issue: 7
Pages: 1331-1342
Publication
First Author: Kim ST
Year: 2018
Journal: PLoS One
Title: The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins.
Volume: 13
Issue: 8
Pages: e0202260
Protein
Organism: Mus musculus/domesticus
Length: 379  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 517  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
Publication
First Author: Xie Y
Year: 1999
Journal: EMBO J
Title: The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain.
Volume: 18
Issue: 23
Pages: 6832-44
Publication
First Author: Wang H
Year: 2018
Journal: Cell Death Dis
Title: Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice.
Volume: 9
Issue: 2
Pages: 76
Publication
First Author: Li T
Year: 2016
Journal: PLoS Genet
Title: Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.
Volume: 12
Issue: 5
Pages: e1006054
Protein
Organism: Mus musculus/domesticus
Length: 950  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 242  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1889  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1892  
Fragment?: false
Publication
First Author: Tasaki T
Year: 2005
Journal: Mol Cell Biol
Title: A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.
Volume: 25
Issue: 16
Pages: 7120-36
Protein
Organism: Mus musculus/domesticus
Length: 849  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 850  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1757  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1755  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1757  
Fragment?: false
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89