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Search results 3401 to 3500 out of 4700 for Notch1

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Type Details Score
Publication
20499347 | J:233131
First Author: Tao J
Year: 2010
Journal: J Bone Miner Res
Title: Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent.
Volume: 25
Issue: 10
Pages: 2175-83
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Publication
27125305 | J:236122
First Author: Gekas C
Year: 2016
Journal: Leukemia
Title: β-Catenin is required for T-cell leukemia initiation and MYC transcription downstream of Notch1.
Volume: 30
Issue: 10
Pages: 2002-2010
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Publication
25295490 | J:225340
 
First Author: Chanrion M
Year: 2014
Journal: Nat Commun
Title: Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut.
Volume: 5
Pages: 5005
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Publication
37454290 | J:339293
First Author: Jannaway M
Year: 2023
Journal: Cell Rep
Title: VEGFR3 is required for button junction formation in lymphatic vessels.
Volume: 42
Issue: 7
Pages: 112777
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Publication
28094257 | J:244565
 
First Author: Yue F
Year: 2017
Journal: Nat Commun
Title: Pten is necessary for the quiescence and maintenance of adult muscle stem cells.
Volume: 8
Pages: 14328
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Publication
32961023 | J:326593
First Author: Bi HR
Year: 2021
Journal: CNS Neurosci Ther
Title: Neuron-specific deletion of presenilin enhancer2 causes progressive astrogliosis and age-related neurodegeneration in the cortex independent of the Notch signaling.
Volume: 27
Issue: 2
Pages: 174-185
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Publication
15277242 | J:91518
First Author: Kiaris H
Year: 2004
Journal: Am J Pathol
Title: Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium.
Volume: 165
Issue: 2
Pages: 695-705
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HT Experiment
E-GEOD-58712 | Cyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Series Id: GSE58712
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Allele
Notch1<tm6.1Rko> | MGI:5523515
Name: notch 1; targeted mutation 6.1, Raphael Kopan
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Strain
MGI:5634566 | STOCK Notch1<tm4(cre)Rko>/J
Attribute String: mutant stock, targeted mutation
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Allele
Notch2<tm3.1Rko> | MGI:5523517
Name: notch 2; targeted mutation 3.1, Raphael Kopan
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Notch2<tm1Bmc> | MGI:3621957
Name: notch 2; targeted mutation 1, Brent McCright
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Allele
Tg(RNU6-gRNA:Notch1,KRT14-cas9)2Kesa | MGI:6394107
Name: transgene insertion 2, Kei Sakamoto
Allele Type: Transgenic
Attribute String: Endonuclease, Null/knockout
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Allele
Tg(ACTB-NOTCH1)1Shn | MGI:3044583
Name: transgene insertion 1, Jie Shen
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6144570 | ICR.Cg-Tg(CAG-cat,-Notch1)1Ysa/YsaRbrc
Attribute String: mutant strain, congenic, transgenic
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Allele
Tg(KRT14-Notch*/ESR1)CA4Fmw | MGI:5824128
Name: transgene insertion CA4, Fiona M Watt
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
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Strain
MGI:5432151 | B6.Cg-Gt(ROSA)26Sor<tm1(NOTCH1/GFP)Xhsu> Tg(Lck-cre)548Jxm
Attribute String: transgenic, mutant strain, congenic
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Allele
Gt(ROSA)26Sor<tm1(Notch1)Dam> | MGI:2684314
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Douglas A Melton
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Strain
MGI:3767657 | STOCK Gt(ROSA)26Sor<tm1(Notch1)Dam>/J
Attribute String: mutant stock, targeted mutation
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Publication
23954701 | J:328408
First Author: Zanotti S
Year: 2013
Journal: Osteoarthritis Cartilage
Title: Interleukin 6 mediates selected effects of Notch in chondrocytes.
Volume: 21
Issue: 11
Pages: 1766-73
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Allele
Tg(RNU6-gRNA:Notch1,KRT14-cas9)1Kesa | MGI:6394115
Name: transgene insertion 1, Kei Sakamoto
Allele Type: Transgenic
Attribute String: Endonuclease, Null/knockout
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Allele
Tg(Actb-NOTCH1)2Shn | MGI:3044584
Name: transgene insertion 2, Jie Shen
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Notch1)1Anc/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch2/Notch2
Background: involves: 129S1/Sv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Lck-cre)548Jxm/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Lck-cre)548Jxm
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eef1a1/Eef1a1<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: C57BL/6 * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
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Publication
35451473 | J:325723
 
First Author: Duvall K
Year: 2022
Journal: Development
Title: Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis.
Volume: 149
Issue: 10
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Publication
24485662 | J:315873
First Author: Weisberg SP
Year: 2014
Journal: Cell Rep
Title: ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.
Volume: 6
Issue: 3
Pages: 528-40
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Publication
31526760 | J:279349
First Author: Jackstadt R
Year: 2019
Journal: Cancer Cell
Title: Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Volume: 36
Issue: 3
Pages: 319-336.e7
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Publication
18758477 | J:140988
First Author: Bellavia D
Year: 2008
Journal: Oncogene
Title: Notch3: from subtle structural differences to functional diversity.
Volume: 27
Issue: 38
Pages: 5092-8
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Publication
18588871 | J:138714
First Author: Rowan S
Year: 2008
Journal: Dev Biol
Title: Notch signaling regulates growth and differentiation in the mammalian lens.
Volume: 321
Issue: 1
Pages: 111-22
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Publication
19536265 | J:197167
First Author: Buonamici S
Year: 2009
Journal: Nature
Title: CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Volume: 459
Issue: 7249
Pages: 1000-4
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Publication
23752615 | J:204823
First Author: Zhang P
Year: 2013
Journal: J Immunol
Title: Notch-regulated periphery B cell differentiation involves suppression of E protein function.
Volume: 191
Issue: 2
Pages: 726-36
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Publication
24817584 | J:213585
First Author: Liu J
Year: 2014
Journal: Genesis
Title: Constitutive notch signaling in adult transgenic mice inhibits bFGF-induced angiogenesis and blocks ovarian follicle development.
Volume: 52
Issue: 9
Pages: 809-16
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Publication
36503993 | J:338389
First Author: Belyea BC
Year: 2023
Journal: Clin Sci (Lond)
Title: Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype.
Volume: 137
Issue: 1
Pages: 35-45
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Publication
29664186 | J:268206
First Author: Dai Q
Year: 2018
Journal: Stem Cells
Title: Notch Signaling Regulates Lgr5+ Olfactory Epithelium Progenitor/Stem Cell Turnover and Mediates Recovery of Lesioned Olfactory Epithelium in Mouse Model.
Volume: 36
Issue: 8
Pages: 1259-1272
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Publication
25264928 | J:223490
First Author: Savoy-Burke G
Year: 2014
Journal: PLoS One
Title: Activated notch causes deafness by promoting a supporting cell phenotype in developing auditory hair cells.
Volume: 9
Issue: 9
Pages: e108160
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Publication
31797926 | J:285635
First Author: Shu Y
Year: 2019
Journal: Nat Commun
Title: Renewed proliferation in adult mouse cochlea and regeneration of hair cells.
Volume: 10
Issue: 1
Pages: 5530
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Protein Coding Gene
MGI:1202301 | Itch
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8C863
Organism: Mus musculus/domesticus
Length: 864  
Fragment?: false
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Publication
16103066 | J:100770
First Author: Beverly LJ
Year: 2005
Journal: Cancer Res
Title: Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression.
Volume: 65
Issue: 16
Pages: 7159-68
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Publication
24423059 | J:210099
 
First Author: Paes de Faria J
Year: 2014
Journal: BMC Neurosci
Title: New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development.
Volume: 15
Pages: 12
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Strain
MGI:3687998 | C57BL/6J-Tg(ACTB-NOTCH1)1Shn/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
22493066 | J:185821
First Author: Wen Y
Year: 2012
Journal: Mol Cell Biol
Title: Constitutive Notch activation upregulates Pax7 and promotes the self-renewal of skeletal muscle satellite cells.
Volume: 32
Issue: 12
Pages: 2300-11
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Allele
Tg(CAG-Bgeo,-NOTCH1,-EGFP)1Lbe | MGI:3703057
Name: transgene insertion 1, Corinne G Lobe
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Publication
23727022 | J:199099
First Author: Zender S
Year: 2013
Journal: Cancer Cell
Title: A critical role for notch signaling in the formation of cholangiocellular carcinomas.
Volume: 23
Issue: 6
Pages: 784-95
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Genotype
Genotype
Symbol: Mesp1/Mesp1<+> Tg(CAG-cat,-Notch1)1Ysa/?
Background: involves: C3H * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mesp2/Mesp2 Psen1/Psen1
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eef1a1/Eef1a1<+> Tg(Mx1-cre)1Cgn/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch2/Notch2
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1<+>
Background: involves: C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
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HT Experiment
E-GEOD-67889 | Sequential Notch activation regulates ventricular chamber development
Series Id: GSE67889
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-54976 | Gene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor
Series Id: GSE54976
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
22354878 | J:181633
First Author: Liu Z
Year: 2012
Journal: Dev Dyn
Title: In vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.
Volume: 241
Issue: 4
Pages: 684-96
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Publication
33512383 | J:307793
First Author: Tardivon D
Year: 2021
Journal: Blood
Title: Notch signaling promotes disease initiation and progression in murine chronic lymphocytic leukemia.
Volume: 137
Issue: 22
Pages: 3079-3092
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Publication
18818392 | J:143346
First Author: Kim YW
Year: 2008
Journal: Blood
Title: Defective Notch activation in microenvironment leads to myeloproliferative disease.
Volume: 112
Issue: 12
Pages: 4628-38
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Publication
32213630 | J:288582
 
First Author: Peired AJ
Year: 2020
Journal: Sci Transl Med
Title: Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells.
Volume: 12
Issue: 536
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Publication
20733081 | J:164383
First Author: Pan W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear.
Volume: 107
Issue: 36
Pages: 15798-803
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Publication
25301628 | J:217437
First Author: Magnusson JP
Year: 2014
Journal: Science
Title: A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse.
Volume: 346
Issue: 6206
Pages: 237-41
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Publication
26876172 | J:235693
First Author: Tesone AJ
Year: 2016
Journal: Cell Rep
Title: Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells.
Volume: 14
Issue: 7
Pages: 1774-1786
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Publication
33774049 | J:304930
   
First Author: Canalis E
Year: 2021
Journal: J Biol Chem
Title: Activation of Notch3 in osteoblasts/osteocytes causes compartment-specific changes in bone remodeling.
Pages: 100583
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Publication
32908186 | J:306657
First Author: López-López S
Year: 2020
Journal: Sci Rep
Title: NOTCH3 signaling is essential for NF-κB activation in TLR-activated macrophages.
Volume: 10
Issue: 1
Pages: 14839
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Publication
25164209 | J:317772
First Author: Rusanescu G
Year: 2014
Journal: J Cell Mol Med
Title: Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord.
Volume: 18
Issue: 10
Pages: 2103-16
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Publication
18250475 | J:131973
First Author: Jurynczyk M
Year: 2008
Journal: J Immunol
Title: Notch3 inhibition in myelin-reactive T cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis.
Volume: 180
Issue: 4
Pages: 2634-40
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HT Experiment
E-GEOD-40527 | Expression Analysis of Whole Thymus and Thymic Tumors on the Sdl Mouse Model
Series Id: GSE40527
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE190330 | single cell RNA sequencing of adult (P60) vomeronasal organ
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
28321121 | J:249414
First Author: Kramer AC
Year: 2017
Journal: Leukemia
Title: Dnmt3a regulates T-cell development and suppresses T-ALL transformation.
Volume: 31
Issue: 11
Pages: 2479-2490
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Publication
33665264 | J:307609
 
First Author: Sharma M
Year: 2021
Journal: Data Brief
Title: Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.
Volume: 35
Pages: 106873
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Publication
25658374 | J:244950
First Author: Verhein KC
Year: 2015
Journal: Environ Health Perspect
Title: Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.
Volume: 123
Issue: 8
Pages: 799-805
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Protein
Q7TPU6
Organism: Mus musculus/domesticus
Length: 739  
Fragment?: false
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Publication
16530044 | -
First Author: Nam Y
Year: 2006
Journal: Cell
Title: Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Volume: 124
Issue: 5
Pages: 973-83
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Publication
18758478 | -
First Author: Kovall RA
Year: 2008
Journal: Oncogene
Title: More complicated than it looks: assembly of Notch pathway transcription complexes.
Volume: 27
Issue: 38
Pages: 5099-109
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Publication
18758483 | J:141198
First Author: McElhinny AS
Year: 2008
Journal: Oncogene
Title: Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways.
Volume: 27
Issue: 38
Pages: 5138-47
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Publication
16510869 | J:106711
First Author: Shen H
Year: 2006
Journal: Genes Dev
Title: The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis.
Volume: 20
Issue: 6
Pages: 675-88
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Publication
17317671 | -
First Author: Zhao Y
Year: 2007
Journal: J Biol Chem
Title: The notch regulator MAML1 interacts with p53 and functions as a coactivator.
Volume: 282
Issue: 16
Pages: 11969-81
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Publication
17875709 | -
First Author: Alves-Guerra MC
Year: 2007
Journal: Cancer Res
Title: Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival.
Volume: 67
Issue: 18
Pages: 8690-8
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Publication
16880534 | -
First Author: Chiang MY
Year: 2006
Journal: Mol Cell Biol
Title: Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1.
Volume: 26
Issue: 16
Pages: 6261-71
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Publication
19150886 | -
First Author: Liu H
Year: 2009
Journal: Circ Res
Title: NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1.
Volume: 104
Issue: 4
Pages: 466-75
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Publication
15961999 | -
First Author: Wu L
Year: 2005
Journal: EMBO J
Title: Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation.
Volume: 24
Issue: 13
Pages: 2391-402
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Publication
15546612 | -
First Author: Fryer CJ
Year: 2004
Journal: Mol Cell
Title: Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.
Volume: 16
Issue: 4
Pages: 509-20
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Publication
26318021 | J:226412
First Author: Biehl MJ
Year: 2015
Journal: Dev Biol
Title: Rbpj-κ mediated Notch signaling plays a critical role in development of hypothalamic Kisspeptin neurons.
Volume: 406
Issue: 2
Pages: 235-46
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Publication
33609440 | J:309291
First Author: Machado L
Year: 2021
Journal: Cell Stem Cell
Title: Tissue damage induces a conserved stress response that initiates quiescent muscle stem cell activation.
Volume: 28
Issue: 6
Pages: 1125-1135.e7
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Publication
27993983 | J:238419
First Author: Wang C
Year: 2017
Journal: Development
Title: Ascl2 inhibits myogenesis by antagonizing the transcriptional activity of myogenic regulatory factors.
Volume: 144
Issue: 2
Pages: 235-247
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Strain
MGI:3703350 | STOCK Tg(CAG-Bgeo,-NOTCH1,-EGFP)1Lbe/J
Attribute String: transgenic, mutant stock
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Publication
- | J:119129
     
First Author: Liu J
Year: 2007
Journal: MGI Direct Data Submission
Title: Constitutive notch signaling in adult transgenic mice inhibits bFGF-induced angiogenesis and blocks ovarian follicle development
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Publication
21781958 | J:176609
First Author: Goldberg LB
Year: 2011
Journal: Dev Biol
Title: Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis.
Volume: 358
Issue: 1
Pages: 23-32
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Genotype
Genotype
Symbol: Hey1/Hey1 Mesp1/Mesp1<+> Tg(CAG-cat,-Notch1)1Ysa/?
Background: involves: 129S7/SvEvBrd * C3H * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Shh/Shh<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre/Esr1*)35.10Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Neurog3-cre/Esr1*)1Dam/?
Background: involves: 129S4/SvJae * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mx1-cre)1Cgn/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hes1/Hes1<+>
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Wt1-cre)#Jbeb/?
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Six2/Six2<+>
Background: involves: 129S4/SvJaeSor * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Neurog3-cre/ERT2)1Able/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col1a1-cre)1Kry/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Six3-cre)69Frty/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Publication
3119223 | -
First Author: Kelley MR
Year: 1987
Journal: Cell
Title: Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus.
Volume: 51
Issue: 4
Pages: 539-48
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