|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 401 to 430 out of 430 for Sycp1

<< First    < Previous  |  Next >    Last >>
0.02s
Type Details Score
Allele
Name: transgene insertion 1, Arikuni Uchimura
Allele Type: Transgenic
Attribute String: Recombinase
Strain
Attribute String: mutant strain, coisogenic, transgenic
Strain
Attribute String: mutant strain, coisogenic, transgenic
Allele
Name: synaptonemal complex protein 1; endonuclease-mediated mutation 1, Synbal
Allele Type: Endonuclease-mediated
Attribute String: Endonuclease, Reporter
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Protein Domain
Type: Family
Description: The synaptonemal complex (SC) is a tripartite structure that physically links homologous chromosomes during prophase I. The SC has a zipper-like structure composed of two lateral elements (LEs) and a central element (CE). Transverse filaments, composed of SYCP1 molecules, bridge the gap between one LE and the CE.Syce2/CESC1 localises to the CE and interacts with the transverse filament protein SYCP1. Its localization to the CE is dependent on recruitment by SYCP1 []. Syce2/ CESC1 is required for synaptonemal complex assembly and also for double strand break repair and homologous recombination [].
Allele
Name: myocardial infarction associated transcript (non-protein coding); targeted mutation 1, Shinichi Nakagawa
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication  
First Author: Ip JY
Year: 2016
Journal: Sci Rep
Title: Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine.
Volume: 6
Pages: 27204
Publication
First Author: Yang L
Year: 2021
Journal: Theranostics
Title: Ablation of lncRNA Miat attenuates pathological hypertrophy and heart failure.
Volume: 11
Issue: 16
Pages: 7995-8007
Genotype
Symbol: Miat/Miat
Background: B6.Cg-Miat
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Uchimura A
Year: 2009
Journal: PLoS One
Title: DNA polymerase delta is required for early mammalian embryogenesis.
Volume: 4
Issue: 1
Pages: e4184
Publication  
First Author: Park M
Year: 2016
Journal: Sci Rep
Title: SOHLH2 is essential for synaptonemal complex formation during spermatogenesis in early postnatal mouse testes.
Volume: 6
Pages: 20980
Publication
First Author: Biswas U
Year: 2016
Journal: PLoS Genet
Title: Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis.
Volume: 12
Issue: 10
Pages: e1006389
Publication
First Author: Galán-Martínez J
Year: 2022
Journal: Sci Rep
Title: TCFL5 deficiency impairs the pachytene to diplotene transition during spermatogenesis in the mouse.
Volume: 12
Issue: 1
Pages: 10956
Publication
First Author: Hernández-Hernández A
Year: 2016
Journal: J Cell Sci
Title: The central element of the synaptonemal complex in mice is organized as a bilayered junction structure.
Volume: 129
Issue: 11
Pages: 2239-49
Publication
First Author: Fraune J
Year: 2013
Journal: Genetics
Title: Phylogenies of central element proteins reveal the dynamic evolutionary history of the mammalian synaptonemal complex: ancient and recent components.
Volume: 195
Issue: 3
Pages: 781-93
Publication
First Author: Li Y
Year: 2019
Journal: Mol Reprod Dev
Title: Sohlh1 is required for synaptonemal complex formation by transcriptionally regulating meiotic genes during spermatogenesis in mice.
Volume: 86
Issue: 3
Pages: 252-264
Publication
First Author: Peng KL
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance.
Volume: 119
Issue: 37
Pages: e2203738119
Publication
First Author: Onishi K
Year: 2017
Journal: J Neurosci
Title: Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development.
Volume: 37
Issue: 35
Pages: 8444-8458
Publication
First Author: Toyoda S
Year: 2014
Journal: Neuron
Title: Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.
Volume: 82
Issue: 1
Pages: 94-108
Publication
First Author: Guiraldelli MF
Year: 2018
Journal: PLoS Genet
Title: SHOC1 is a ERCC4-(HhH)2-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis.
Volume: 14
Issue: 5
Pages: e1007381
Publication
First Author: Koornneef L
Year: 2022
Journal: PLoS Genet
Title: Multi-color dSTORM microscopy in Hormad1-/- spermatocytes reveals alterations in meiotic recombination intermediates and synaptonemal complex structure.
Volume: 18
Issue: 7
Pages: e1010046
Publication
First Author: Tarusawa E
Year: 2016
Journal: BMC Biol
Title: Establishment of high reciprocal connectivity between clonal cortical neurons is regulated by the Dnmt3b DNA methyltransferase and clustered protocadherins.
Volume: 14
Issue: 1
Pages: 103
Publication
First Author: Katori S
Year: 2017
Journal: Sci Rep
Title: Protocadherin-αC2 is required for diffuse projections of serotonergic axons.
Volume: 7
Issue: 1
Pages: 15908
Publication
First Author: Noguchi Y
Year: 2009
Journal: J Biol Chem
Title: Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Pcdha cluster.
Volume: 284
Issue: 46
Pages: 32002-14
Publication  
First Author: Hasegawa S
Year: 2016
Journal: Front Mol Neurosci
Title: Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting.
Volume: 9
Pages: 155
Publication      
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center