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Search results 101 to 197 out of 197 for Gmps

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1775122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3274122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3287422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
     
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266022
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Specimen Label: MH207; Specimen C910
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1624622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Note: Expression was strong in the digestive system.
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1721422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1646922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1736222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1683322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1700022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530794
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1876522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Note: Expression was detected in the immune system.
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1833322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3287022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3557722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Specimen Label: MH207; Specimen C910
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Note: Expression was weak in the skull (base and vault).
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
Probe: MGI:4354287
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421785
Age: embryonic day 14.5
Image: MH207; Specimen C910
Note: Expression was strong in whisker follicle.
Specimen Label: MH207; Specimen C910
Detected: true
Specimen Num: 1
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
GSE65753 | Analysis of wildtype and Xbp1-deficient hematopoietic progenitor cell transcriptomes
Series Id: E-GEOD-65753
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
28514689 | J:259038
First Author: Kawamura S
Year: 2017
Journal: Immunity
Title: Identification of a Human Clonogenic Progenitor with Strict Monocyte Differentiation Potential: A Counterpart of Mouse cMoPs.
Volume: 46
Issue: 5
Pages: 835-848.e4
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Publication
37146584 | J:335875
First Author: Hao X
Year: 2023
Journal: Cell Stem Cell
Title: Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal.
Volume: 30
Issue: 5
Pages: 648-664.e8
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Publication
28355185 | J:252515
First Author: Hérault A
Year: 2017
Journal: Nature
Title: Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Volume: 544
Issue: 7648
Pages: 53-58
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Publication
26051941 | J:336341
First Author: Pina C
Year: 2015
Journal: Cell Rep
Title: Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis.
Volume: 11
Issue: 10
Pages: 1503-10
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Publication
33214666 | J:301479
First Author: AhYoung AP
Year: 2020
Journal: Commun Biol
Title: Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage.
Volume: 3
Issue: 1
Pages: 687
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Publication
32579887 | J:346842
First Author: Kwok I
Year: 2020
Journal: Immunity
Title: Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor.
Volume: 53
Issue: 2
Pages: 303-318.e5
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Publication
31852898 | J:282726
First Author: Chen X
Year: 2019
Journal: Nat Commun
Title: MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.
Volume: 10
Issue: 1
Pages: 5767
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Publication
17079688 | J:114679
First Author: Iwasaki H
Year: 2006
Journal: Genes Dev
Title: The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Volume: 20
Issue: 21
Pages: 3010-21
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Publication
18455126 | J:134770
First Author: Chen W
Year: 2008
Journal: Cancer Cell
Title: Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells.
Volume: 13
Issue: 5
Pages: 432-40
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Publication
23200826 | J:191060
First Author: Griseri T
Year: 2012
Journal: Immunity
Title: Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation.
Volume: 37
Issue: 6
Pages: 1116-29
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Publication
19900465 | -
First Author: Maruoka S
Year: 2010
Journal: J Mol Biol
Title: Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3.
Volume: 395
Issue: 2
Pages: 417-29
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Publication
10688693 | -
First Author: Grimaldi C
Year: 2000
Journal: Curr Microbiol
Title: Genetic organization and polymorphism of the guaA gene encoding the GMP synthetase in Lactobacillus rhamnosus.
Volume: 40
Issue: 4
Pages: 245-9
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Protein Domain
IPR025777 | GMPS_ATP_PPase_dom
Type: Domain
Description: Guanosine 5'-monophosphate synthetase (GMPS) is a widespread enzyme seen inall domains of life. GMPS is required for the final step of the de novosynthesis of guanine nucleotides, converting xanthosine 5'-monophosphate (XMP)into guanosine 5'-monophosphate (GMP), a precursor of DNA and RNA. GMPSconsists of two catalytic units, glutamine amidotransferase (GATase) and ATP pyrophosphatase (ATP-PPase). GATase hydrolyzes glutamineto yield glutamate and ammonia, while ATP-PPase utilises ammonia to convertadenyl xanthosine 5'-monophosphate (adenyl-XMP) into GMP. The two catalyticunits are either encoded by a single gene (two-domain type) in eucaryotes,bacteria, and some archaea, or encoded by two separate genes (two-subunittype) in other archaea. In two-domain-type GMPS, the GATase domain is locatedin the N-terminal half, and the ATP-PPase domain is located in the C-terminalhalf; in two-subunit-type GMPS, these two units exist as separatepolypeptides. ATP-PPase consists of two domains (N-domain and C-domain). TheN-domain contains an ATP-binding platform called P-loop,whereas the C-domain contains the XMP-binding site and also contributes tohomodimerisation [, , ].The GMP synthetase ATP-PPase ATP-binding domain is a twisted, five-strandedparallel β-sheet sandwiched between helical layers. Itcontains a glycine rich ATP-binding motif called the "P-loop motif"locatedafter the first β-strand [, ].
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Publication
21427174 | J:172072
First Author: Khalfin-Rabinovich Y
Year: 2011
Journal: Int Immunol
Title: PML is a key component for the differentiation of myeloid progenitor cells to macrophages.
Volume: 23
Issue: 4
Pages: 287-96
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Publication
24677539 | J:212417
First Author: Satpathy AT
Year: 2014
Journal: Blood
Title: Runx1 and Cbfβ regulate the development of Flt3+ dendritic cell progenitors and restrict myeloproliferative disorder.
Volume: 123
Issue: 19
Pages: 2968-77
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Publication
20393130 | J:161537
First Author: Böiers C
Year: 2010
Journal: Blood
Title: Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.
Volume: 115
Issue: 24
Pages: 5061-8
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Publication
21828131 | J:179035
First Author: Wara AK
Year: 2011
Journal: Blood
Title: TGF-β1 signaling and Krüppel-like factor 10 regulate bone marrow-derived proangiogenic cell differentiation, function, and neovascularization.
Volume: 118
Issue: 24
Pages: 6450-60
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Publication
28550122 | J:247685
First Author: Dougher CWL
Year: 2017
Journal: J Leukoc Biol
Title: The blood-borne sialyltransferase ST6Gal-1 is a negative systemic regulator of granulopoiesis.
Volume: 102
Issue: 2
Pages: 507-516
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Publication
22353998 | J:185005
First Author: Alemdehy MF
Year: 2012
Journal: Blood
Title: Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice.
Volume: 119
Issue: 20
Pages: 4723-30
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Publication
19234178 | J:146252
First Author: Ohmori K
Year: 2009
Journal: J Immunol
Title: IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen.
Volume: 182
Issue: 5
Pages: 2835-41
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Publication
19779039 | J:155489
First Author: Kimura A
Year: 2009
Journal: Blood
Title: The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
Volume: 114
Issue: 21
Pages: 4721-8
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Publication
21527932 | J:174571
First Author: Yuan J
Year: 2011
Journal: Leukemia
Title: Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells.
Volume: 25
Issue: 8
Pages: 1335-43
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Publication
15657291 | J:95651
First Author: Nutt SL
Year: 2005
Journal: J Exp Med
Title: Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors.
Volume: 201
Issue: 2
Pages: 221-31
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Publication
23831605 | J:214023
First Author: Schuster MB
Year: 2013
Journal: Exp Hematol
Title: Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors.
Volume: 41
Issue: 10
Pages: 882-893.e16
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Publication
23922855 | J:203273
First Author: Zhang Y
Year: 2013
Journal: PLoS One
Title: Suppression of cytochrome p450 reductase enhances long-term hematopoietic stem cell repopulation efficiency in mice.
Volume: 8
Issue: 7
Pages: e69913
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Publication
22303456 | J:184213
First Author: Saulnier N
Year: 2012
Journal: PLoS One
Title: ERK1 regulates the hematopoietic stem cell niches.
Volume: 7
Issue: 1
Pages: e30788
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Protein
Q3THK7
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
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Protein
B2RRH9
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
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Publication
8548458 | -
First Author: Tesmer JJ
Year: 1996
Journal: Nat Struct Biol
Title: The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families.
Volume: 3
Issue: 1
Pages: 74-86
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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