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Search results 101 to 200 out of 241 for Slc22a5

0.036s
Type Details Score
GXD Expression  
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2828128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1794828
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1867628
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:474839
Assay Type: RNA in situ
Annotation Date: 2011-02-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4888623
Age: embryonic day 14.5
Image: Table S1
Specimen Label: Table S1
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1867928
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:1927928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Specimen Num: 1
GXD Expression    
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2813628
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1897628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5299070
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2823628
Stage: TS28
Assay Id: MGI:5543054
Age: postnatal day 84
Image: GUDMAP:14503
Specimen Label: GUDMAP:14503
Detected: false
Specimen Num: 1
Publication
First Author: Tamai I
Year: 2000
Journal: J Biol Chem
Title: Molecular and functional characterization of organic cation/carnitine transporter family in mice.
Volume: 275
Issue: 51
Pages: 40064-72
Publication
First Author: Lamhonwah AM
Year: 2003
Journal: Biochem Biophys Res Commun
Title: A third human carnitine/organic cation transporter (OCTN3) as a candidate for the 5q31 Crohn's disease locus (IBD5).
Volume: 301
Issue: 1
Pages: 98-101
Publication
First Author: Kato Y
Year: 2005
Journal: Mol Pharmacol
Title: PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.
Volume: 67
Issue: 3
Pages: 734-43
Publication
First Author: Ushikai M
Year: 2011
Journal: Mol Genet Metab
Title: Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart.
Volume: 102
Issue: 3
Pages: 349-55
Publication
First Author: Masuda M
Year: 1997
Journal: FEBS Lett
Title: A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice.
Volume: 408
Issue: 2
Pages: 221-4
Publication
First Author: Peng J
Year: 2002
Journal: Mol Biol Rep
Title: Identification of human CDV-1R and mouse Cdv-1R, two novel proteins with putative signal peptides, especially highly expressed in testis and increased with the male sex maturation.
Volume: 29
Issue: 4
Pages: 353-62
Publication
First Author: Tomomura M
Year: 1992
Journal: Biochim Biophys Acta
Title: Abnormal expression of urea cycle enzyme genes in juvenile visceral steatosis (jvs) mice.
Volume: 1138
Issue: 2
Pages: 167-71
Publication
First Author: Hotta K
Year: 1996
Journal: Biochim Biophys Acta
Title: Altered expression of carnitine palmitoyltransferase II in liver, muscle, and heart of mouse strain with juvenile visceral steatosis.
Volume: 1289
Issue: 1
Pages: 131-5
Publication
First Author: Ramsay RR
Year: 2001
Journal: Biochim Biophys Acta
Title: Molecular enzymology of carnitine transfer and transport.
Volume: 1546
Issue: 1
Pages: 21-43
Publication  
First Author: Lamhonwah AM
Year: 2020
Journal: Clin Chim Acta
Title: Expression of the organic cation/carnitine transporter family (Octn1,-2 and-3) in mdx muscle and heart: Implications for early carnitine therapy in Duchenne muscular dystrophy to improve cellular carnitine homeostasis.
Volume: 505
Pages: 92-97
Publication
First Author: Ozaki K
Year: 2011
Journal: Lab Invest
Title: Carnitine is necessary to maintain the phenotype and function of brown adipose tissue.
Volume: 91
Issue: 5
Pages: 704-10
Publication  
First Author: Hayakawa JI
Year: 1990
Journal: Mouse Genome
Title: Inheritance of juvenile visceral steatosis (jvs) found in C3H-H-2o mice.
Volume: 86
Pages: 261
Publication
First Author: Yoshimine K
Year: 1997
Journal: J Mol Cell Cardiol
Title: Altered expression of atrial natriuretic peptide and contractile protein genes in hypertrophied ventricle of JVS mice with systemic carnitine deficiency.
Volume: 29
Issue: 2
Pages: 571-8
Publication
First Author: Wen G
Year: 2010
Journal: Biochem Pharmacol
Title: Mouse OCTN2 is directly regulated by peroxisome proliferator-activated receptor alpha (PPARalpha) via a PPRE located in the first intron.
Volume: 79
Issue: 5
Pages: 768-76
Publication
First Author: Uenaka R
Year: 1996
Journal: J Biochem
Title: Increased expression of carnitine palmitoyltransferase I gene is repressed by administering L-carnitine in the hearts of carnitine-deficient juvenile visceral steatosis mice.
Volume: 119
Issue: 3
Pages: 533-40
Publication
First Author: van Vlies N
Year: 2007
Journal: Biochim Biophys Acta
Title: PPAR alpha-activation results in enhanced carnitine biosynthesis and OCTN2-mediated hepatic carnitine accumulation.
Volume: 1767
Issue: 9
Pages: 1134-42
Publication
First Author: Toledo F
Year: 2006
Journal: Nucleic Acids Res
Title: RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses.
Volume: 34
Issue: 13
Pages: e92
Publication
First Author: Tomomura M
Year: 1994
Journal: Biochim Biophys Acta
Title: Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency.
Volume: 1226
Issue: 3
Pages: 307-14
Publication
First Author: Tomomura M
Year: 1992
Journal: FEBS Lett
Title: Proto-oncogene c-jun and c-fos messenger RNAs increase in the liver of carnitine-deficient juvenile visceral steatosis (jvs) mice.
Volume: 311
Issue: 1
Pages: 63-6
Publication
First Author: Tomomura M
Year: 1996
Journal: FEBS Lett
Title: Long-chain fatty acids suppress the induction of urea cycle enzyme genes by glucocorticoid action.
Volume: 399
Issue: 3
Pages: 310-2
Publication
First Author: Shekhawat PS
Year: 2004
Journal: Pediatr Res
Title: Carnitine content and expression of mitochondrial beta-oxidation enzymes in placentas of wild-type (OCTN2(+/+)) and OCTN2 Null (OCTN2(-/-)) Mice.
Volume: 56
Issue: 3
Pages: 323-8
Publication
First Author: D'Argenio G
Year: 2010
Journal: J Biol Chem
Title: Colon OCTN2 gene expression is up-regulated by peroxisome proliferator-activated receptor gamma in humans and mice and contributes to local and systemic carnitine homeostasis.
Volume: 285
Issue: 35
Pages: 27078-87
Publication
First Author: Monte JC
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.
Volume: 323
Issue: 2
Pages: 429-36
Publication
First Author: Cui JY
Year: 2012
Journal: Toxicol Sci
Title: RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.
Volume: 127
Issue: 2
Pages: 592-608
Publication
First Author: Wenderfer SE
Year: 2000
Journal: Genomics
Title: Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.
Volume: 63
Issue: 3
Pages: 354-73
Publication
First Author: Cossette SM
Year: 2014
Journal: Biol Open
Title: Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.
Volume: 4
Issue: 1
Pages: 48-61
Publication  
First Author: Ghnaimawi S
Year: 2022
Journal: Front Physiol
Title: The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring's Muscle Development and Energy Homeostasis.
Volume: 13
Pages: 881624
Publication  
First Author: Zhang Y
Year: 2015
Journal: Nat Commun
Title: Maternal bile acid transporter deficiency promotes neonatal demise.
Volume: 6
Pages: 8186
Publication
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication
First Author: Tamai I
Year: 2013
Journal: Biopharm Drug Dispos
Title: Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21).
Volume: 34
Issue: 1
Pages: 29-44
Allele
Name: transgene insertion, Edward M Rubin
Allele Type: Transgenic
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion, Edward M Rubin
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele
Name: transgene insertion 1, Edward M Rubin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele  
Name: deletion, Chr 11, Edward M Rubin 1
Allele Type: Targeted
Strain
Attribute String: mutant stock, targeted mutation, deletion
Strain
Attribute String: mutant strain, targeted mutation, coisogenic, deletion
Genotype
Symbol: Del(11Irf1-D11Mit23)1Rub/Del(11Irf1-D11Mit23)1Rub
Background: 129/Sv-Del(11Irf1-D11Mit23)1Rub
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Del(11Irf1-D11Mit23)1Rub/+
Background: 129/Sv-Del(11Irf1-D11Mit23)1Rub
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Loots GG
Year: 2000
Journal: Science
Title: Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons.
Volume: 288
Issue: 5463
Pages: 136-40
Strain
Attribute String: mutant stock, transgenic, targeted mutation, deletion
Genotype
Symbol: Del(11Irf1-D11Mit23)1Rub/Del(11Irf1-D11Mit23)1Rub Tg(A94G6)1Rub/?
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Halliwell B
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis.
Volume: 470
Issue: 2
Pages: 245-250
Publication  
First Author: Gründemann D
Year: 2012
Journal: Prev Med
Title: The ergothioneine transporter controls and indicates ergothioneine activity--a review.
Volume: 54 Suppl
Pages: S71-4
Publication
First Author: Pochini L
Year: 2013
Journal: J Biomol Screen
Title: OCTN cation transporters in health and disease: role as drug targets and assay development.
Volume: 18
Issue: 8
Pages: 851-67
Protein Domain
Type: Family
Description: This entry represents Solute carrier family 22 members 4/5 (SLC22A4/5) and similar proteins from chordates. This protein family belong to the organic cation transporter family and to the major facilitator superfamily (MFS) of membrane transport proteins. MSF proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement [, , ].SLC22A4/5 are sodium-ion dependent transporters. SLC22A4 is a low affinity carnitine transporter, highly specific for the uptake of ergothioneine (ET), a thiolated derivative of histidine with antioxidant properties. ET is a natural compound produced only by certain fungi and bacteria and must be absorbed from the diet by humans and other vetebrates [, ]. SLC22A5 is a high affinity carnitine transporter involved in the active cellular uptake of carnitine [, ].
Publication
First Author: Longo N
Year: 2016
Journal: Biochim Biophys Acta
Title: Carnitine transport and fatty acid oxidation.
Volume: 1863
Issue: 10
Pages: 2422-35
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory