Shortage in chiasmata 1 orthologue, the plant SHOC1 orthologue in animals, has been shown to act at mid-stage steps of the crossover (CO) formation process. It also interacts with TEX11, another protein important for the formation of COs. SHOC1 has associated ATPase activity, but lacks endonuclease activity, so it has been speculated that SHOC1 may protect against dissociation by anti-crossover activities instead of having a role in cleaving recombination intermediates to produce COs [].
This entry represents a group of plant proteins, including shortage in chiasmata 1 (SHOC1) from Arabidopsis. SHOC1 is essential for the formation of class I meiotic crossovers [, ].
This entry represents the Protein SPO16 homologue (SPO16, also known as Synaptonemal complex reinforcing element SCRE), including the mammalian orthologue of budding yeast Spo16. It plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC), resulting in the SC stabilization which ensures the progression of meiotic prophase I in male and female germ cells [. It promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1 []. It is also required for the localization of TEX11 and MSH4 to recombination intermediates [].
