This entry represents leucine-rich repeat-containing protein 16A (LRRC16A). In humans it is also known as CARMIL1, which belongs to the CARMIL (capping protein, Arp2/3 and Myosin-I linker) family. CARMIL family members are potential regulators of actin capping proteins, which control the polymerisation of actin filaments by capping their barbed ends [, ]. CARMIL1 is essential for cell migration and may control lamellipodial actin assembly via effects on Trio and Rac1 [, ].
