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Search results 101 to 160 out of 160 for Ttc4

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0.022s
Type Details Score
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_10
Specimen Label: euxassay_002091_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_11
Specimen Label: euxassay_002091_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_12
Specimen Label: euxassay_002091_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_13
Specimen Label: euxassay_002091_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_14
Specimen Label: euxassay_002091_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_15
Specimen Label: euxassay_002091_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_16
Specimen Label: euxassay_002091_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_17
Specimen Label: euxassay_002091_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_18
Specimen Label: euxassay_002091_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_19
Specimen Label: euxassay_002091_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_20
Specimen Label: euxassay_002091_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_21
Specimen Label: euxassay_002091_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_22
Specimen Label: euxassay_002091_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_23
Specimen Label: euxassay_002091_23
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:1686191
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4828991
Age: embryonic day 14.5
Image: euxassay_002091_24
Specimen Label: euxassay_002091_24
Detected: true
Specimen Num: 24
Publication
First Author: Dmitriev RI
Year: 2014
Journal: J Cell Biochem
Title: Two distinct nuclear localization signals in mammalian MSL1 regulate its function.
Volume: 115
Issue: 11
Pages: 1967-73
Publication
First Author: Jurecic R
Year: 1998
Journal: Anal Biochem
Title: Identification and cloning of differentially expressed genes by long-distance differential display.
Volume: 259
Issue: 2
Pages: 235-44
Publication
First Author: Lee YJ
Year: 2000
Journal: FEBS Lett
Title: Mit1/Lb9 and Copg2, new members of mouse imprinted genes closely linked to Peg1/Mest(1).
Volume: 472
Issue: 2-3
Pages: 230-4
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Crevel G
Year: 2008
Journal: PLoS One
Title: The human TPR protein TTC4 is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells.
Volume: 3
Issue: 3
Pages: e0001737
Publication
First Author: Schopf FH
Year: 2019
Journal: Mol Cell
Title: The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2.
Volume: 74
Issue: 1
Pages: 73-87.e8
Publication
First Author: Crevel G
Year: 2001
Journal: J Cell Sci
Title: The Drosophila Dpit47 protein is a nuclear Hsp90 co-chaperone that interacts with DNA polymerase alpha.
Volume: 114
Issue: Pt 11
Pages: 2015-25
Protein Domain
Type: Domain
Description: Co-chaperones are helper interacting proteins that modulate the chaperone cycle, being involved in substrate specificity and stimulation of chaperone activity of HSP90/70 and include other heat shock proteins, TPR containing proteins, cyclophilins and others. The TPR containing proteins possess an N-terminal TPR domain, which are more closely related to each other than to TPR domains from other proteins with different functionality [, ], which is involved in HSP90/70 direct interaction. The first N-terminal residues prior to the TRP domain and the C-terminal domain are involved and important for domain interplay and stabilisation of its interactions []. The Hsp90 chaperone machinery in eukaryotes comprises a number of distinct accessory factors, among them TTC4 from human and its homologues Cns1 from yeast and Dpit47 from Drosophila, structurally and functionally conserved from yeast to human. Cns1 is one of the few essential co-chaperones in yeast, important for maintaining translation elongation, specifically chaperoning the elongation factor eEF2. Cns1 interacts with Hgh1 and forms a quaternary complex together with eEF2 and Hsp90 mediating the proper folding and solubility of eEF2. Recently, the C-terminal structure has been solved and is called the "wheel"domain according to its 2D projection. It shows an overall fold consisting of a twisted five-stranded beta sheet surrounded by several alpha helices [].This entry represents the wheel domain found at the C terminus of yeast Cns1, human TTC4 and Drosophila Dpit47 proteins.
Protein
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7