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Search results 3601 to 3700 out of 4769 for Hc

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Type Details Score
Publication  
First Author: Choi I
Year: 2015
Journal: Nat Commun
Title: LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase.
Volume: 6
Pages: 8255
Publication
First Author: Sundberg TB
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.
Volume: 111
Issue: 34
Pages: 12468-73
Publication
First Author: Chaney AM
Year: 2023
Journal: Sci Transl Med
Title: PET imaging of TREM1 identifies CNS-infiltrating myeloid cells in a mouse model of multiple sclerosis.
Volume: 15
Issue: 702
Pages: eabm6267
Publication
First Author: Kwek SS
Year: 2018
Journal: Nat Commun
Title: A systematic approach to the development of a safe live attenuated Zika vaccine.
Volume: 9
Issue: 1
Pages: 1031
Publication
First Author: McElrath C
Year: 2021
Journal: Nat Commun
Title: Critical role of interferons in gastrointestinal injury repair.
Volume: 12
Issue: 1
Pages: 2624
Publication  
First Author: Ouyang X
Year: 2011
Journal: Nat Commun
Title: Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation.
Volume: 2
Pages: 314
Publication
First Author: Bittner S
Year: 2013
Journal: Nat Med
Title: Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.
Volume: 19
Issue: 9
Pages: 1161-5
Publication
First Author: Carrer A
Year: 2019
Journal: Cancer Discov
Title: Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis.
Volume: 9
Issue: 3
Pages: 416-435
Publication
First Author: Chen PS
Year: 2011
Journal: J Clin Invest
Title: miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans.
Volume: 121
Issue: 9
Pages: 3442-55
Publication
First Author: Shih YC
Year: 2018
Journal: Circ Res
Title: Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation.
Volume: 122
Issue: 8
Pages: 1052-1068
Publication
First Author: Yang X
Year: 2017
Journal: J Clin Invest
Title: Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.
Volume: 127
Issue: 4
Pages: 1505-1516
Publication
First Author: Alamshah A
Year: 2016
Journal: Diabetes Obes Metab
Title: L-arginine promotes gut hormone release and reduces food intake in rodents.
Volume: 18
Issue: 5
Pages: 508-18
Publication
First Author: Budinger GR
Year: 2011
Journal: PLoS One
Title: Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms.
Volume: 6
Issue: 4
Pages: e18525
Publication  
First Author: Toepfer CN
Year: 2019
Journal: Sci Transl Med
Title: Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.
Volume: 11
Issue: 476
Publication
First Author: McGavigan AK
Year: 2015
Journal: Int J Obes (Lond)
Title: L-cysteine suppresses ghrelin and reduces appetite in rodents and humans.
Volume: 39
Issue: 3
Pages: 447-55
Publication
First Author: Caruso P
Year: 2012
Journal: Circ Res
Title: A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples.
Volume: 111
Issue: 3
Pages: 290-300
Publication
First Author: Kim SU
Year: 2011
Journal: Neurobiol Aging
Title: Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage.
Volume: 32
Issue: 6
Pages: 1054-68
Publication
First Author: Park JG
Year: 2011
Journal: Circ Res
Title: Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice.
Volume: 109
Issue: 7
Pages: 739-49
Publication
First Author: Li Y
Year: 2007
Journal: J Immunol
Title: Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins.
Volume: 179
Issue: 12
Pages: 8322-31
Publication
First Author: Tsai WC
Year: 2012
Journal: J Clin Invest
Title: MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis.
Volume: 122
Issue: 8
Pages: 2884-97
Publication  
First Author: Kim DH
Year: 2019
Journal: Sci Transl Med
Title: Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis.
Volume: 11
Issue: 501
Publication
First Author: Boettger T
Year: 2003
Journal: EMBO J
Title: Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold.
Volume: 22
Issue: 20
Pages: 5422-34
Publication
First Author: Chang CS
Year: 2022
Journal: iScience
Title: Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice.
Volume: 25
Issue: 2
Pages: 103738
Publication
First Author: Sato T
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function.
Volume: 115
Issue: 27
Pages: E6291-E6300
Publication  
First Author: Scherger AK
Year: 2019
Journal: JCI Insight
Title: Activated gp130 signaling selectively targets B cell differentiation to induce mature lymphoma and plasmacytoma.
Volume: 4
Issue: 15
Publication
First Author: Yoshida Y
Year: 2014
Journal: Immunity
Title: The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation.
Volume: 40
Issue: 2
Pages: 187-98
Publication
First Author: Holtschke T
Year: 1996
Journal: Cell
Title: Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene.
Volume: 87
Issue: 2
Pages: 307-17
Publication  
First Author: Sohn HA
Year: 2022
Journal: Cells
Title: Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers.
Volume: 11
Issue: 9
Publication
First Author: Spinner DS
Year: 2008
Journal: J Virol
Title: Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
Volume: 82
Issue: 21
Pages: 10701-8
Publication
First Author: Cannell IG
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication.
Volume: 107
Issue: 12
Pages: 5375-80
Publication
First Author: van Vugt MA
Year: 2010
Journal: PLoS Biol
Title: A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.
Volume: 8
Issue: 1
Pages: e1000287
Publication
First Author: Bartolome F
Year: 2013
Journal: Neuron
Title: Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels.
Volume: 78
Issue: 1
Pages: 57-64
Publication
First Author: Ahmad W
Year: 1998
Journal: Science
Title: Alopecia universalis associated with a mutation in the human hairless gene.
Volume: 279
Issue: 5351
Pages: 720-4
Publication
First Author: Dawson DW
Year: 2007
Journal: Oncogene
Title: Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.
Volume: 26
Issue: 29
Pages: 4243-52
Publication
First Author: Sheu JJ
Year: 2009
Journal: Cancer Res
Title: Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma.
Volume: 69
Issue: 6
Pages: 2568-76
Publication
First Author: Ryoo S
Year: 2008
Journal: Circ Res
Title: Endothelial arginase II: a novel target for the treatment of atherosclerosis.
Volume: 102
Issue: 8
Pages: 923-32
Publication
First Author: Li Z
Year: 2009
Journal: Blood
Title: Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma.
Volume: 114
Issue: 19
Pages: 4158-68
Publication
First Author: Filimonenko M
Year: 2010
Journal: Mol Cell
Title: The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.
Volume: 38
Issue: 2
Pages: 265-79
Publication
First Author: Höhne M
Year: 2011
Journal: Mol Cell Biol
Title: The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins.
Volume: 31
Issue: 16
Pages: 3241-51
Publication
First Author: Podowski M
Year: 2012
Journal: J Clin Invest
Title: Angiotensin receptor blockade attenuates cigarette smoke-induced lung injury and rescues lung architecture in mice.
Volume: 122
Issue: 1
Pages: 229-40
Publication
First Author: Ruan YC
Year: 2012
Journal: Nat Med
Title: Activation of the epithelial Na+ channel triggers prostaglandin Eâ‚‚ release and production required for embryo implantation.
Volume: 18
Issue: 7
Pages: 1112-7
Publication
First Author: Bae KB
Year: 2011
Journal: Transgenic Res
Title: Overexpression of Jazf1 induces cardiac malformation through the upregulation of pro-apoptotic genes in mice.
Volume: 20
Issue: 5
Pages: 1019-31
Publication
First Author: Esposito T
Year: 2013
Journal: Hum Mol Genet
Title: Unique X-linked familial FSGS with co-segregating heart block disorder is associated with a mutation in the NXF5 gene.
Volume: 22
Issue: 18
Pages: 3654-66
Publication
First Author: McCoy F
Year: 2013
Journal: Mol Cell
Title: Metabolic activation of CaMKII by coenzyme A.
Volume: 52
Issue: 3
Pages: 325-39
Publication
First Author: Kubagawa H
Year: 2015
Journal: J Immunol
Title: Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR.
Volume: 194
Issue: 9
Pages: 4055-7
Publication
First Author: Lang PA
Year: 2013
Journal: Cell Death Differ
Title: Reactive oxygen species delay control of lymphocytic choriomeningitis virus.
Volume: 20
Issue: 4
Pages: 649-58
Publication
First Author: Yang CH
Year: 2015
Journal: Biochim Biophys Acta
Title: EGFR over-expression in non-small cell lung cancers harboring EGFR mutations is associated with marked down-regulation of CD82.
Volume: 1852
Issue: 7
Pages: 1540-9
Publication
First Author: Zhou J
Year: 2016
Journal: Oncogene
Title: Loss of DAB2IP in RCC cells enhances their growth and resistance to mTOR-targeted therapies.
Volume: 35
Issue: 35
Pages: 4663-74
Publication
First Author: He F
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis.
Volume: 114
Issue: 40
Pages: 10542-10547
Publication
First Author: Morita S
Year: 2017
Journal: Cell Metab
Title: Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes.
Volume: 25
Issue: 4
Pages: 883-897.e8
Publication
First Author: Huang PY
Year: 2017
Journal: Nat Genet
Title: Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma.
Volume: 49
Issue: 11
Pages: 1624-1632
Publication
First Author: Yang D
Year: 2018
Journal: Cancer Discov
Title: Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin.
Volume: 8
Issue: 10
Pages: 1316-1331
Publication
First Author: Lee HW
Year: 2019
Journal: PLoS One
Title: Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus.
Volume: 14
Issue: 8
Pages: e0221798
Publication
First Author: Heier C
Year: 2015
Journal: J Biol Chem
Title: G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
Volume: 290
Issue: 43
Pages: 26141-50
Publication
First Author: Piálek J
Year: 2008
Journal: J Hered
Title: Development of unique house mouse resources suitable for evolutionary studies of speciation.
Volume: 99
Issue: 1
Pages: 34-44
Publication
First Author: Reis MB
Year: 2020
Journal: Nat Commun
Title: Interleukin-1 receptor-induced PGE2 production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation.
Volume: 11
Issue: 1
Pages: 5433
Publication      
First Author: Teixeira VP
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling.
Publication
First Author: Kovalenko A
Year: 2021
Journal: Cancer Res
Title: Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Volume: 81
Issue: 8
Pages: 2086-2100
Publication
First Author: Ganguly S
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet.
Volume: 12
Issue: 3
Pages: 891-920
Publication
First Author: Norrmén C
Year: 2014
Journal: Cell Rep
Title: mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.
Volume: 9
Issue: 2
Pages: 646-60
Publication
First Author: Wu L
Year: 2021
Journal: Kidney Int
Title: Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy.
Volume: 100
Issue: 1
Pages: 107-121
Publication
First Author: Paschall AV
Year: 2015
Journal: J Immunol
Title: IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.
Volume: 194
Issue: 5
Pages: 2369-79
Publication
First Author: Xi Y
Year: 2021
Journal: Sci Adv
Title: The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1.
Volume: 7
Issue: 36
Pages: eabg9241
Publication  
First Author: Wang J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
Volume: 118
Issue: 39
Publication
First Author: Moon MY
Year: 2013
Journal: Cell Signal
Title: Involvement of small GTPase RhoA in the regulation of superoxide production in BV2 cells in response to fibrillar Aβ peptides.
Volume: 25
Issue: 9
Pages: 1861-9
Publication
First Author: Lim JS
Year: 2015
Journal: Nat Med
Title: Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy.
Volume: 21
Issue: 4
Pages: 395-400
Publication
First Author: Hoffman MT
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice.
Volume: 11
Issue: 2
Pages: 349-369
Publication
First Author: Yan M
Year: 2016
Journal: J Immunol
Title: Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.
Volume: 196
Issue: 5
Pages: 1999-2003
Publication
First Author: Cannons JL
Year: 2021
Journal: Cell Rep
Title: PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8(+) T cells at the expense of central memory.
Volume: 37
Issue: 2
Pages: 109804
Publication  
First Author: Yang J
Year: 2023
Journal: Cancer Lett
Title: Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10.
Volume: 555
Pages: 216025
Publication
First Author: Scales MK
Year: 2022
Journal: PLoS Genet
Title: Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer.
Volume: 18
Issue: 7
Pages: e1010315
Publication  
First Author: Sieow JL
Year: 2023
Journal: Int J Mol Sci
Title: Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma.
Volume: 24
Issue: 1
Publication
First Author: Zhu M
Year: 2023
Journal: Cancer Cell
Title: Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden.
Volume: 41
Issue: 10
Pages: 1731-1748.e8
Publication
First Author: Rathjen T
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Cell Insulin Signaling Regulates CXCR4 (C-X-C Motif Chemokine Receptor 4) and Limits Leukocyte Adhesion to Endothelium.
Volume: 42
Issue: 7
Pages: e217-e227
Publication
First Author: Sardar D
Year: 2023
Journal: Science
Title: Induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation.
Volume: 380
Issue: 6650
Pages: eade0027
Publication
First Author: Wang IH
Year: 2022
Journal: Nat Neurosci
Title: Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing.
Volume: 25
Issue: 4
Pages: 484-492
Publication  
First Author: Kannan-Sundhari A
Year: 2020
Journal: Front Cell Dev Biol
Title: Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival.
Volume: 8
Pages: 576654
Publication
First Author: Rahman A
Year: 2005
Journal: FEBS Lett
Title: High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice.
Volume: 579
Issue: 28
Pages: 6411-6
Publication
First Author: Oikawa T
Year: 1985
Journal: J Immunogenet
Title: Genetic differences between two substrains of NZB mice.
Volume: 12
Issue: 1
Pages: 71-3
Publication  
First Author: Taylor BA
Year: 1985
Journal: Mouse News Lett
Title: Mapping additional 7S RNA sequences.
Volume: 72
Pages: 110
HT Experiment
Series Id: GSE35888
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: congenic, mutant strain, transgenic, major histocompatibility congenic
Publication
First Author: Akerström B
Year: 1990
Journal: Trends Biochem Sci
Title: An intriguing member of the lipocalin protein family: alpha 1-microglobulin.
Volume: 15
Issue: 6
Pages: 240-3
Protein Domain
Type: Family
Description: The lipocalin family can be subdivided into kernal and outlier sets. The kernal lipocalins form the largest self consistent group, comprising the subfamily of alpha-1-microglobulins. The outlier lipocalins form several smaller distinct subgroups: the OBPs, the von Ebner's gland proteins, alpha-1-acid glycoproteins, tick histamine binding proteins and the nitrophorins.Alpha-1-microglobulin (A1M), also known as protein HC (for Heterogeneous Charge), is a low molecular weight protein component of plasma first discovered in pathological human urine. It is a member of the lipocalin superfamily. Although much is now known of its structure and properties, the function and physiological role of A1M remains unclear, although evidence suggests that it functions in the regulation of the immune system. A1M is known to exist in both a free form and complexed to other macromolecules: immunoglobulin A (IgA) in humans and alpha-1-inhibitor-3 in the rat. Free A1M is a monomeric protein composed of one 188 residue polypeptide and contains three cysteines, two of which (residues 75 and 173) form a conserved intra-molecular disulphide link []. A1M is glycosylated by three separate carbohydrate chains: two complex carbohydrates are N-linked to asparagines at residues 17 and 96, and the other simple carbohydrate is O-linked to threonine at position 5. 22% of the total molecular mass of the protein is derived from carbohydrate. Free A1M is extremely heterogeneous in charge, and is found tightly associated with a chromophore. This chromophoric group is covalently bound to the free cysteine residue at position 34. It also binds retinol as a major ligand, but this is probably distinct from the its covalent chromophore. The glycosylation is different between species. The principal sites of A1M synthesis are the liver and kidney. Half of all human plasma A1M (about 0.03mg/ml) forms a 1:1 complex with about 5% of plasma immunoglobulin A. The resulting macromolecular complex has a molecular weight of 200000, anda plasma concentration of 0.3mg/ml. It can exhibit both antibody activity and affect many of the biological actions of free A1M []. A1M has many affects on the immune system. It inhibits stimulation of cultured lymphocytes by protein antigens; it can induce cell division of lymphocytes, a mitogenic effect that can either be enhanced or inhibited by the action of other plasma components; it inhibits neutrophil granulocyte migration in vitro; and it inhibits chemotaxis.
Publication
First Author: Town T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The stumpy gene is required for mammalian ciliogenesis.
Volume: 105
Issue: 8
Pages: 2853-8
Publication
First Author: Imuta Y
Year: 2009
Journal: Dev Dyn
Title: Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).
Volume: 238
Issue: 1
Pages: 210-22
Publication
First Author: Walters BJ
Year: 2017
Journal: Cell Rep
Title: In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.
Volume: 19
Issue: 2
Pages: 307-320
Publication
First Author: Luo Z
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development.
Volume: 119
Issue: 32
Pages: e2119850119
Publication
First Author: Petitpré C
Year: 2022
Journal: Nat Commun
Title: Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification.
Volume: 13
Issue: 1
Pages: 3878
Publication
First Author: Yamashita T
Year: 2018
Journal: PLoS Genet
Title: High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor.
Volume: 14
Issue: 7
Pages: e1007552
Publication    
First Author: Morcom L
Year: 2021
Journal: Elife
Title: DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation.
Volume: 10
Publication
First Author: Xia M
Year: 2023
Journal: Stem Cell Reports
Title: Generation of innervated cochlear organoid recapitulates early development of auditory unit.
Volume: 18
Issue: 1
Pages: 319-336
Publication  
First Author: Hayashi Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Norrie disease protein is essential for cochlear hair cell maturation.
Volume: 118
Issue: 39