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Search results 201 to 279 out of 279 for Pkhd1

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0.029s
Type Details Score
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, African clawed
Interaction Experiment
Description: Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.
DO Term
Allele
Name: transgene insertion 1, Peter Igarashi
Allele Type: Transgenic
Attribute String: Recombinase
Protein
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: true
Protein Domain
Type: Domain
Description: This entry represents a domain found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix [].
Publication  
First Author: Kuo IY
Year: 2019
Journal: Sci Signal
Title: Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.
Volume: 12
Issue: 580
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: He QY
Year: 2006
Journal: Bioinformatics
Title: G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss.
Volume: 22
Issue: 18
Pages: 2189-91
Publication
First Author: Raman A
Year: 2017
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.
Volume: 28
Issue: 9
Pages: 2708-2719
Genotype
Symbol: Mirc1/Mirc1 Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mir214/Mir214 Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Wang Q
Year: 2018
Journal: Kidney Int
Title: Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease.
Volume: 93
Issue: 2
Pages: 403-415
Publication
First Author: Cao Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models.
Volume: 106
Issue: 51
Pages: 21819-24
Publication
First Author: Trott JF
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.
Volume: 315
Issue: 6
Pages: F1855-F1868
Publication  
First Author: Grosch M
Year: 2021
Journal: J Cell Sci
Title: A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Volume: 134
Issue: 16
Publication
First Author: Zhou X
Year: 2015
Journal: Hum Mol Genet
Title: Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Volume: 24
Issue: 14
Pages: 3982-93
Genotype
Symbol: Pkd1/Pkd1 Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkd1)248Som/? Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mir21a/Mir21a Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Aboudehen K
Year: 2017
Journal: J Am Soc Nephrol
Title: Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.
Volume: 28
Issue: 10
Pages: 2887-2900
Publication
First Author: Ye H
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: The regulatory 1α subunit of protein kinase A modulates renal cystogenesis.
Volume: 313
Issue: 3
Pages: F677-F686
Publication
First Author: Aboudehen K
Year: 2018
Journal: J Biol Chem
Title: Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.
Volume: 293
Issue: 24
Pages: 9388-9398
Genotype
Symbol: Hoxb3os/Hoxb3os Pkd1/Pkd1 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Besse W
Year: 2017
Journal: J Clin Invest
Title: Isolated polycystic liver disease genes define effectors of polycystin-1 function.
Volume: 127
Issue: 5
Pages: 1772-1785
Publication
First Author: Hogan MC
Year: 2003
Journal: Hum Mol Genet
Title: PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression.
Volume: 12
Issue: 6
Pages: 685-98
Publication
First Author: Gresh L
Year: 2004
Journal: EMBO J
Title: A transcriptional network in polycystic kidney disease.
Volume: 23
Issue: 7
Pages: 1657-68
Publication
First Author: Belyea BC
Year: 2023
Journal: Clin Sci (Lond)
Title: Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype.
Volume: 137
Issue: 1
Pages: 35-45
Publication
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
Publication
First Author: Flowers EM
Year: 2018
Journal: Nat Commun
Title: Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.
Volume: 9
Issue: 1
Pages: 814
Publication  
First Author: Lakhia R
Year: 2020
Journal: JCI Insight
Title: Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
Volume: 5
Issue: 7
Publication      
First Author: Ishikawa Y
Year: 2019
Journal: J Am Soc Nephrol
Title: Spliced XBP1 Rescues Renal Interstitial Inflammation Due to Loss of Sec63 in Collecting Ducts.
Publication
First Author: Chen L
Year: 2015
Journal: J Clin Invest
Title: Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease.
Volume: 125
Issue: 6
Pages: 2399-412
Publication
First Author: Cai Y
Year: 2014
Journal: J Clin Invest
Title: Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Volume: 124
Issue: 12
Pages: 5129-44
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kif3a/Kif3a<+> Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 1383  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1361  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1361  
Fragment?: false
Publication  
First Author: Hajarnis S
Year: 2017
Journal: Nat Commun
Title: microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Volume: 8
Pages: 14395
Publication
First Author: Hajarnis S
Year: 2018
Journal: J Am Soc Nephrol
Title: Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.
Volume: 29
Issue: 2
Pages: 518-531
Publication
First Author: Zhang C
Year: 2021
Journal: J Am Soc Nephrol
Title: Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease.
Volume: 32
Issue: 1
Pages: 41-51
Publication
First Author: Weisser I
Year: 2024
Journal: J Am Soc Nephrol
Title: Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease.
Volume: 35
Issue: 1
Pages: 41-55
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kif3a/Kif3a Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Lakhia R
Year: 2016
Journal: J Am Soc Nephrol
Title: MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Volume: 27
Issue: 8
Pages: 2319-30
Publication
First Author: Patel V
Year: 2008
Journal: Hum Mol Genet
Title: Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.
Volume: 17
Issue: 11
Pages: 1578-90
Publication
First Author: Shibazaki S
Year: 2008
Journal: Hum Mol Genet
Title: Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.
Volume: 17
Issue: 11
Pages: 1505-16
Publication    
First Author: Li Y
Year: 2023
Journal: Elife
Title: Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
Volume: 12
Publication
First Author: Ma M
Year: 2013
Journal: Nat Genet
Title: Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease.
Volume: 45
Issue: 9
Pages: 1004-12
Protein
Organism: Mus musculus/domesticus
Length: 4249  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 4247  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 4249  
Fragment?: false