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Search results 1 to 100 out of 426 for Grm5

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
2915 | GRM5
Type: gene
Organism: human
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Gene
451472 | GRM5
Type: gene
Organism: chimpanzee
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Gene
485146 | GRM5
Type: gene
Organism: dog, domestic
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Gene
100336861 | GRM5
Type: gene
Organism: cattle
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Gene
373933 | GRM5
Type: gene
Organism: chicken
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Gene
705445 | GRM5
Type: gene
Organism: macaque, rhesus
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Gene
100485273 | grm5
Type: gene
Organism: frog, western clawed
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Gene
24418 | Grm5
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1351342 | Grm5
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
440040 | GRM5P1
Type: gene
Organism: human
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Gene
100873989 | GRM5-AS1
Type: gene
Organism: human
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Publication
34029630 | J:311119
 
First Author: Xu J
Year: 2021
Journal: Behav Brain Res
Title: Genetic disruption of Grm5 causes complex alterations in motor activity, anxiety and social behaviors.
Volume: 411
Pages: 113378
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Publication
16040064 | J:179570
 
First Author: MarĂ­n YE
Year: 2005
Journal: Neuropharmacology
Title: Grm5 expression is not required for the oncogenic role of Grm1 in melanocytes.
Volume: 49 Suppl 1
Pages: 70-9
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190465
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Grm5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190465
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Grm5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190465
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Grm5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190465
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Grm5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190465
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Grm5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190465
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Grm5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6174451
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190465
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Grm5
Detected: true
Specimen Num: 7
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Protein
B7ZMP7
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
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Protein
Q4VA56
Organism: Mus musculus/domesticus
Length: 1065  
Fragment?: true
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Publication
28982591 | J:260245
First Author: Bossi S
Year: 2018
Journal: Neurobiol Dis
Title: Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia.
Volume: 109
Issue: Pt A
Pages: 44-53
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Strain
MGI:5450931 | B6;129P2-Grm8<tm1Dgen>/H
Attribute String: targeted mutation, mutant stock
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Strain
MGI:5450926 | B6;129P2-Grm5<tm1Dgen>/H
Attribute String: mutant stock, targeted mutation
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Publication
35746896 | J:335422
First Author: Å pirkovĂ¡ A
Year: 2022
Journal: Biol Reprod
Title: Glutamate can act as a signaling molecule in mouse preimplantation embryos†.
Volume: 107
Issue: 4
Pages: 916-927
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Protein Coding Gene
MGP_CAROLIEiJ_G0029969 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032491 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1351342 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031518 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032399 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031236 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013189 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031079 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
30259400 | J:342309
First Author: GarcĂ­a-Montes JR
Year: 2019
Journal: Mol Neurobiol
Title: Genetic Knockdown of mGluR5 in Striatal D1R-Containing Neurons Attenuates L-DOPA-Induced Dyskinesia in Aphakia Mice.
Volume: 56
Issue: 6
Pages: 4037-4050
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Publication
22902169 | J:271823
First Author: Parkitna JR
Year: 2013
Journal: Biol Psychiatry
Title: Novelty-seeking behaviors and the escalation of alcohol drinking after abstinence in mice are controlled by metabotropic glutamate receptor 5 on neurons expressing dopamine d1 receptors.
Volume: 73
Issue: 3
Pages: 263-70
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Publication
24672017 | J:271824
First Author: Fieblinger T
Year: 2014
Journal: J Neurosci
Title: Mechanisms of dopamine D1 receptor-mediated ERK1/2 activation in the parkinsonian striatum and their modulation by metabotropic glutamate receptor type 5.
Volume: 34
Issue: 13
Pages: 4728-40
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Publication
24885390 | J:310946
 
First Author: Overk CR
Year: 2014
Journal: Mol Neurodegener
Title: Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies.
Volume: 9
Pages: 18
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Publication
31420117 | J:282634
First Author: Holz A
Year: 2019
Journal: Neuron
Title: Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation.
Volume: 104
Issue: 2
Pages: 338-352.e7
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Publication
35984881 | J:343467
First Author: Liang W
Year: 2022
Journal: Sci Adv
Title: Loss of schizophrenia-related miR-501-3p in mice impairs sociability and memory by enhancing mGluR5-mediated glutamatergic transmission.
Volume: 8
Issue: 33
Pages: eabn7357
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Publication
34070808 | J:308417
 
First Author: MartĂ­n-Belmonte A
Year: 2021
Journal: Int J Mol Sci
Title: The Density of Group I mGlu5 Receptors Is Reduced along the Neuronal Surface of Hippocampal Cells in a Mouse Model of Alzheimer's Disease.
Volume: 22
Issue: 11
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Publication
24886239 | J:316460
 
First Author: Hamilton A
Year: 2014
Journal: Mol Brain
Title: Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease.
Volume: 7
Pages: 40
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Publication
34360592 | J:341667
 
First Author: Zangrandi L
Year: 2021
Journal: Int J Mol Sci
Title: Loss of mGluR5 in D1 Receptor-Expressing Neurons Improves Stress Coping.
Volume: 22
Issue: 15
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Publication
23291536 | J:214204
 
First Author: Parmentier-Batteur S
Year: 2014
Journal: Neuropharmacology
Title: Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic target.
Volume: 82
Pages: 161-73
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Publication
19321764 | J:147275
First Author: Xu J
Year: 2009
Journal: J Neurosci
Title: mGluR5 has a critical role in inhibitory learning.
Volume: 29
Issue: 12
Pages: 3676-84
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Publication
30930274 | J:285631
 
First Author: Carvalho TG
Year: 2019
Journal: Neurochem Int
Title: Metabotropic glutamate receptor 5 ablation accelerates age-related neurodegeneration and neuroinflammation.
Volume: 126
Pages: 218-228
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Publication
11431513 | J:103903
First Author: Huber KM
Year: 2001
Journal: J Neurophysiol
Title: Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.
Volume: 86
Issue: 1
Pages: 321-5
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Publication
35643779 | J:325700
First Author: de Souza JM
Year: 2022
Journal: Sci Rep
Title: mGluR5 ablation leads to age-related synaptic plasticity impairments and does not improve Huntington's disease phenotype.
Volume: 12
Issue: 1
Pages: 8982
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Publication
34199502 | J:320577
 
First Author: Gonzalez-Lozano MA
Year: 2021
Journal: Cells
Title: Reduced mGluR5 Activity Modulates Mitochondrial Function.
Volume: 10
Issue: 6
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Publication
23861896 | J:204284
First Author: Chesworth R
Year: 2013
Journal: PLoS One
Title: The metabotropic glutamate 5 receptor modulates extinction and reinstatement of methamphetamine-seeking in mice.
Volume: 8
Issue: 7
Pages: e68371
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Publication
25639954 | J:220016
First Author: Uematsu K
Year: 2015
Journal: J Neurochem
Title: Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function.
Volume: 132
Issue: 6
Pages: 677-86
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Publication
25666312 | J:329072
First Author: Burrows EL
Year: 2015
Journal: Neuropsychopharmacology
Title: Environmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5.
Volume: 40
Issue: 8
Pages: 1947-56
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Publication
23228523 | J:197069
 
First Author: Inta D
Year: 2013
Journal: Behav Brain Res
Title: Significant increase in anxiety during aging in mGlu5 receptor knockout mice.
Volume: 241
Pages: 27-31
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Publication
38053635 | J:343642
First Author: Ng AN
Year: 2023
Journal: iScience
Title: Amyloid-β(1-42) oligomers enhance mGlu(5)R-dependent synaptic weakening via NMDAR activation and complement C5aR1 signaling.
Volume: 26
Issue: 12
Pages: 108412
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Publication
35379852 | J:325581
First Author: Santos RPM
Year: 2022
Journal: Sci Rep
Title: Metabotropic glutamate receptor 5 knockout rescues obesity phenotype in a mouse model of Huntington's disease.
Volume: 12
Issue: 1
Pages: 5621
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Publication
37566031 | J:339587
 
First Author: Torazza C
Year: 2023
Journal: Cells
Title: Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes.
Volume: 12
Issue: 15
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Publication
33962661 | J:306997
First Author: Imbriglio T
Year: 2021
Journal: Mol Brain
Title: Developmental up-regulation of NMDA receptors in the prefrontal cortex and hippocampus of mGlu5 receptor knock-out mice.
Volume: 14
Issue: 1
Pages: 77
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Publication
24576814 | J:329081
 
First Author: Bird MK
Year: 2014
Journal: Drug Alcohol Depend
Title: The mGlu5 receptor regulates extinction of cocaine-driven behaviours.
Volume: 137
Pages: 83-9
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Publication
28980941 | J:248313
   
First Author: Holst SC
Year: 2017
Journal: Elife
Title: Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation.
Volume: 6
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Publication
16424079 | J:135799
First Author: Storto M
Year: 2006
Journal: Mol Pharmacol
Title: Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors.
Volume: 69
Issue: 4
Pages: 1234-41
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Publication
30971312 | J:290274
First Author: Lim J
Year: 2019
Journal: Mol Brain
Title: Assessment of mGluR5 KO mice under conditions of low stress using a rodent touchscreen apparatus reveals impaired behavioural flexibility driven by perseverative responses.
Volume: 12
Issue: 1
Pages: 37
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Publication
10454358 | J:51151
First Author: Jia Z
Year: 1998
Journal: Learn Mem
Title: Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5.
Volume: 5
Issue: 4-5
Pages: 331-43
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Publication
22819970 | J:188790
First Author: Chen CC
Year: 2012
Journal: Neurosci Lett
Title: mGluR5 knockout mice display increased dendritic spine densities.
Volume: 524
Issue: 1
Pages: 65-8
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Publication
19519626 | J:150200
First Author: She WC
Year: 2009
Journal: Eur J Neurosci
Title: Roles of mGluR5 in synaptic function and plasticity of the mouse thalamocortical pathway.
Volume: 29
Issue: 7
Pages: 1379-96
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Publication
18625255 | J:179420
First Author: Musante V
Year: 2008
Journal: Neuropharmacology
Title: Presynaptic mGlu1 and mGlu5 autoreceptors facilitate glutamate exocytosis from mouse cortical nerve endings.
Volume: 55
Issue: 4
Pages: 474-82
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Publication
28855570 | J:256640
First Author: Yang T
Year: 2017
Journal: Sci Rep
Title: Metabotropic glutamate receptor 5 deficiency inhibits neutrophil infiltration after traumatic brain injury in mice.
Volume: 7
Issue: 1
Pages: 9998
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Publication
30873001 | J:284451
 
First Author: Ramos-Prats A
Year: 2019
Journal: Front Mol Neurosci
Title: An Appraisal of the Influence of the Metabotropic Glutamate 5 (mGlu5) Receptor on Sociability and Anxiety.
Volume: 12
Pages: 30
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Publication
20657349 | J:180856
First Author: Downing C
Year: 2010
Journal: Pharmacogenet Genomics
Title: The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol.
Volume: 20
Issue: 9
Pages: 553-64
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Publication
33195226 | J:308434
 
First Author: Gubert C
Year: 2020
Journal: Front Cell Dev Biol
Title: Microbiome Profiling Reveals Gut Dysbiosis in the Metabotropic Glutamate Receptor 5 Knockout Mouse Model of Schizophrenia.
Volume: 8
Pages: 582320
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Publication
15947794 | J:116384
First Author: Di Giorgi-Gerevini V
Year: 2005
Journal: Cell Death Differ
Title: Endogenous activation of metabotropic glutamate receptors supports the proliferation and survival of neural progenitor cells.
Volume: 12
Issue: 8
Pages: 1124-33
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Publication
23165119 | J:206552
 
First Author: Xiao XL
Year: 2013
Journal: Brain Res
Title: Metabotropic glutamate receptor 5 (mGluR5) regulates proliferation and differentiation of neuronal progenitors in the developmental hippocampus.
Volume: 1493
Pages: 1-12
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Publication
26005851 | J:224479
First Author: Shin S
Year: 2015
Journal: Nat Neurosci
Title: mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress.
Volume: 18
Issue: 7
Pages: 1017-24
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Publication
30401923 | J:268239
First Author: Zeleznikow-Johnston AM
Year: 2018
Journal: Sci Rep
Title: Touchscreen testing reveals clinically relevant cognitive abnormalities in a mouse model of schizophrenia lacking metabotropic glutamate receptor 5.
Volume: 8
Issue: 1
Pages: 16412
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Publication
28645622 | J:254297
 
First Author: Bonifacino T
Year: 2017
Journal: Neuropharmacology
Title: In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1G93A mouse model of amyotrophic lateral sclerosis.
Volume: 123
Pages: 433-445
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Publication
12473093 | J:108073
First Author: Brodkin J
Year: 2002
Journal: Eur J Neurosci
Title: Reduced stress-induced hyperthermia in mGluR5 knockout mice.
Volume: 16
Issue: 11
Pages: 2241-4
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Publication
26417096 | J:227065
First Author: Sidorov MS
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Metabotropic glutamate receptor signaling is required for NMDA receptor-dependent ocular dominance plasticity and LTD in visual cortex.
Volume: 112
Issue: 41
Pages: 12852-7
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Publication
19169252 | J:146136
First Author: Sidiropoulou K
Year: 2009
Journal: Nat Neurosci
Title: Dopamine modulates an mGluR5-mediated depolarization underlying prefrontal persistent activity.
Volume: 12
Issue: 2
Pages: 190-9
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Publication
21152045 | J:167278
First Author: Olsen CM
Year: 2010
Journal: PLoS One
Title: Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5).
Volume: 5
Issue: 11
Pages: e15085
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Publication
12660307 | J:124739
First Author: Kinney GG
Year: 2003
Journal: J Pharmacol Exp Ther
Title: Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents.
Volume: 306
Issue: 1
Pages: 116-23
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Publication
33540617 | J:307550
 
First Author: Fultz EK
Year: 2021
Journal: Int J Mol Sci
Title: ERK-Directed Phosphorylation of mGlu5 Gates Methamphetamine Reward and Reinforcement in Mouse.
Volume: 22
Issue: 3
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Publication
11528416 | J:97288
First Author: Chiamulera C
Year: 2001
Journal: Nat Neurosci
Title: Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice.
Volume: 4
Issue: 9
Pages: 873-4
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Publication
14699440 | J:101782
First Author: Brody SA
Year: 2004
Journal: Mol Psychiatry
Title: Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors.
Volume: 9
Issue: 1
Pages: 35-41
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Publication
25957750 | J:321657
First Author: Tan SZ
Year: 2015
Journal: Neurochem Res
Title: Spatial Learning Requires mGlu5 Signalling in the Dorsal Hippocampus.
Volume: 40
Issue: 6
Pages: 1303-10
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Publication
25505329 | J:218839
First Author: Xu J
Year: 2014
Journal: J Neurosci
Title: Hippocampal metaplasticity is required for the formation of temporal associative memories.
Volume: 34
Issue: 50
Pages: 16762-73
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Publication
33731684 | J:313867
First Author: Kasten CR
Year: 2021
Journal: Transl Psychiatry
Title: BNST specific mGlu5 receptor knockdown regulates sex-dependent expression of negative affect produced by adolescent ethanol exposure and adult stress.
Volume: 11
Issue: 1
Pages: 178
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Publication
38117654 | J:344307
First Author: Lao-Peregrin C
Year: 2024
Journal: Cell Rep
Title: Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk.
Volume: 43
Issue: 1
Pages: 113595
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Publication
29136107 | J:287853
First Author: Stansley BJ
Year: 2018
Journal: Cereb Cortex
Title: Contextual Fear Extinction Induces Hippocampal Metaplasticity Mediated by Metabotropic Glutamate Receptor 5.
Volume: 28
Issue: 12
Pages: 4291-4304
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Publication
18784306 | J:141261
First Author: Grueter BA
Year: 2008
Journal: J Neurosci
Title: In vivo metabotropic glutamate receptor 5 (mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression.
Volume: 28
Issue: 37
Pages: 9261-70
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Publication
19052194 | J:143059
First Author: Wijetunge LS
Year: 2008
Journal: J Neurosci
Title: mGluR5 regulates glutamate-dependent development of the mouse somatosensory cortex.
Volume: 28
Issue: 49
Pages: 13028-37
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