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Search results 101 to 144 out of 144 for Relt

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Type Details Score
Gene
704673 | RELL2
Type: gene
Organism: macaque, rhesus
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Publication
16389068 | -
First Author: Cusick JK
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Identification of RELT homologues that associate with RELT and are phosphorylated by OSR1.
Volume: 340
Issue: 2
Pages: 535-43
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Protein Domain
IPR022248 | TNF_rcpt_RELT
Type: Family
Description: The members of tumor necrosis factor receptor (TNFR) superfamily have been designated as the "guardians of the immune system"due to their roles in immune cell proliferation, differentiation, activation, and death (apoptosis). RELT (receptor expressed in lymphoid tissues) is a member of the TNFR superfamily. The messenger RNA of RELT is especially abundant in hematologic tissues such as spleen, lymph node, and peripheral blood leukocytes as well as in leukemias and lymphomas. RELT is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1 []. RELT like proteins 1 and 2 (RELL1 and RELL2) are two RELT homologues that bind to RELT. The expression of RELL1 at the mRNA level is ubiquitous, whereas expression of RELL2 mRNA is more restricted to particular tissues [].
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Protein
Q8BRJ3
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Protein
Q8K2J7
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: false
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Protein
E9Q3X7
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein
E9Q872
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: false
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Protein
E9Q2K0
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: true
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Protein
Q8CFT0
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Publication
31575895 | J:284660
First Author: Ikeda A
Year: 2019
Journal: Sci Rep
Title: ADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel Development.
Volume: 9
Issue: 1
Pages: 14086
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Allele
Relt<em1Smoc> | MGI:7292012
Name: RELT tumor necrosis factor receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Relt<em1Jpsi> | MGI:6369620
Name: RELT tumor necrosis factor receptor; endonuclease-mediated mutation 1, James P Simmer
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
28688764 | -
First Author: Moua P
Year: 2017
Journal: Biochem Biophys Res Commun
Title: RELT family members activate p38 and induce apoptosis by a mechanism distinct from TNFR1.
Volume: 491
Issue: 1
Pages: 25-32
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Genotype
Genotype
Symbol: Relt/Relt
Background: C57BL/6-Relt
Zygosity: hm
Has Mutant Allele: true
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Allele
Relt<+> | MGI:3049930
   
Name: RELT tumor necrosis factor receptor; wild type
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Publication
22052202 | -
First Author: Cusick JK
Year: 2012
Journal: Mol Cell Biochem
Title: Identification of PLSCR1 as a protein that interacts with RELT family members.
Volume: 362
Issue: 1-2
Pages: 55-63
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Publication
11313261 | J:69353
First Author: Sica GL
Year: 2001
Journal: Blood
Title: RELT, a new member of the tumor necrosis factor receptor superfamily, is selectively expressed in hematopoietic tissues and activates transcription factor NF-kappaB.
Volume: 97
Issue: 9
Pages: 2702-7
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Allele
Relt<tm1Hlee> | MGI:6400520
Name: RELT tumor necrosis factor receptor; targeted mutation 1, Ho Lee
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Relt<tm1(KOMP)Vlcg> | MGI:5085766
Name: RELT tumor necrosis factor receptor; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Relt<Gt(OST422887)Lex> | MGI:4312105
 
Name: RELT tumor necrosis factor receptor; gene trap OST422887, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Relt<em1(IMPC)H> | MGI:6432323
Name: RELT tumor necrosis factor receptor; endonuclease-mediated mutation 1, Harwell
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
Q8BX43
Organism: Mus musculus/domesticus
Length: 436  
Fragment?: false
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Allele
Relt<em1Gpt> | MGI:7305341
Name: RELT tumor necrosis factor receptor; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Relt<tm4a(EUCOMM)Hmgu> | MGI:5511165
Name: RELT tumor necrosis factor receptor; targeted mutation 4a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Relt<tm2e(EUCOMM)Hmgu> | MGI:4436492
Name: RELT tumor necrosis factor receptor; targeted mutation 2e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Relt<tm1e(EUCOMM)Hmgu> | MGI:4435608
Name: RELT tumor necrosis factor receptor; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Relt<tm4e(EUCOMM)Hmgu> | MGI:5511163
Name: RELT tumor necrosis factor receptor; targeted mutation 4e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:6757086 | C57BL/6NTac-Relt<em1(IMPC)H>/H
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Relt/Relt
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6865948 | C57BL/6J-Relt<em1Jpsi>/Mmnc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
16530727 | J:265615
First Author: Polek TC
Year: 2006
Journal: Biochem Biophys Res Commun
Title: The TNF receptor, RELT, binds SPAK and uses it to mediate p38 and JNK activation.
Volume: 343
Issue: 1
Pages: 125-34
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Protein Domain
IPR042315 | RELL1
Type: Family
Description: RELT-like protein 1 (RELL1) belongs to the RELT family. Its overexpression induces activation of MAPK14/p38 cascade [].RELT (receptor expressed in lymphoid tissues) is a member of the TNFR superfamily. The messenger RNA of RELT is especially abundant in hematologic tissues such as spleen, lymph node, and peripheral blood leukocytes as well as in leukemias and lymphomas. RELT is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1 []. RELT like proteins 1 and 2 (RELL1 and RELL2) are two RELT homologues that bind to RELT. The expression of RELL1 at the mRNA level is ubiquitous, whereas expression of RELL2 mRNA is more restricted to particular tissues [].
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DO Term
DOID:0111722 | amelogenesis imperfecta type 3C
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Protein
E9Q812
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: true
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Protein
E9PX33
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
H3BJY5
Organism: Mus musculus/domesticus
Length: 208  
Fragment?: false
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Protein Domain
IPR042313 | RELL2
Type: Family
Description: RELT-like protein 2 (RELL2) belongs to the RELT family. Overexpression of RELL2 induces activation of MAPK14/p38 cascade [].RELT (receptor expressed in lymphoid tissues) is a member of the TNFR superfamily. The messenger RNA of RELT is especially abundant in hematologic tissues such as spleen, lymph node, and peripheral blood leukocytes as well as in leukemias and lymphomas. RELT is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1 []. RELT like proteins 1 and 2 (RELL1 and RELL2) are two RELT homologues that bind to RELT. The expression of RELL1 at the mRNA level is ubiquitous, whereas expression of RELL2 mRNA is more restricted to particular tissues [].
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Protein Domain
IPR034048 | TNFRSF19L_N
Type: Domain
Description: Tumor necrosis factor receptor superfamily member 19-like (TNFRSF19L), also known as receptor expressed in lymphoid tissues (RELT), is especially abundant in hematologic tissues and can stimulate the proliferation of T-cells []. It serves as a substrate for the closely related kinases, odd-skipped related transcription factor 1 (OSR1) and STE20/SPS1-related proline/alanine-rich kinase (SPAK) [, ]; RELT binds SPAK and uses it to mediate p38 and JNK activation, rather than rely on the canonical TRAF pathways for its function. RELT is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. It interacts with phospholipid scramblase 1 (PLSCR1), an interferon-inducible protein that mediates antiviral activity against DNA and RNA viruses; PLSCR1 is a regulator of hepatitis B virus X (HBV X) protein. RELT and PLSCR1 co-localize in intracellular regions of human embryonic kidney-293 cells, with RELT over-expression appearing to alter the localization of PLSCR1 [].This entry represents the N-terminal domain of TNFRSF19L. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].
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Protein
D6RIM1
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: false
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Protein
D3Z306
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
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Protein
D3YWL9
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
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Publication
9538693 | -
First Author: Naismith JH
Year: 1998
Journal: Trends Biochem Sci
Title: Modularity in the TNF-receptor family.
Volume: 23
Issue: 2
Pages: 74-9
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Publication
11796220 | -
First Author: Bodmer JL
Year: 2002
Journal: Trends Biochem Sci
Title: The molecular architecture of the TNF superfamily.
Volume: 27
Issue: 1
Pages: 19-26
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Publication
8387891 | -
First Author: Banner DW
Year: 1993
Journal: Cell
Title: Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume: 73
Issue: 3
Pages: 431-45
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