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Search results 1 to 2 out of 2 for Cnot10

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
Type Details Score
Protein Domain
Type: Family
Description: CNOT10 is part of the CCR4-NOT complex, a major cellular mRNA deadenylase linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. CNOT10 is essential for the integrity of the CCR4-NOT complex and for degradation of many mRNAs [].
Protein Domain
Type: Family
Description: The CCR4-NOT complex plays a key role in mRNA decay in all eukaryotes, thereby contributing importantly to gene expression regulation []. Human C2ORF29 proteins, also known as CNOT11, is a component of the CCR4-NOT complex. CNOT11 interacts with the first amino acids of CNOT1 and with CNOT10 and is required for the association of CNOT10 with the CCR4-NOT complex [].