Type |
Details |
Score |
Strain |
Attribute String: |
strain family |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5648913 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-08-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3519628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5649071 |
Age: |
postnatal week 6 |
Image: |
Hc WT |
|
Specimen Label: |
Hc WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5648913 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-08-19 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3519628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5649071 |
Age: |
postnatal week 6 |
Image: |
Hc KO |
|
Specimen Label: |
Hc KO |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen HC |
Year: |
2007 |
Journal: |
J Virol |
Title: |
Both virus and tumor necrosis factor alpha are critical for endothelium damage in a mouse model of dengue virus-induced hemorrhage. |
Volume: |
81 |
Issue: |
11 |
Pages: |
5518-26 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:945758 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-11-15 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:7548631 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
ED6a Hc |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gervais F |
Year: |
1984 |
Journal: |
J Immunol |
Title: |
Genetic control of resistance to Listeria monocytogenes: regulation of leukocyte inflammatory responses by the Hc locus. |
Volume: |
132 |
Issue: |
4 |
Pages: |
2078-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Natsuume-Sakai S |
Year: |
1985 |
Journal: |
J Immunol |
Title: |
Structural polymorphism of murine complement factor H controlled by a locus located between the Hc and the beta 2M locus on the second chromosome of the mouse. |
Volume: |
134 |
Issue: |
4 |
Pages: |
2600-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dietz HC |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
JR strain 10939 |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Brooke HC |
Year: |
1926 |
Journal: |
J Hered |
Title: |
Hairless mice. |
Volume: |
17 |
Issue: |
5 |
Pages: |
173-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morris HC |
Year: |
1981 |
|
Title: |
The laboratory mouse: a historical perspective |
Volume: |
1 |
|
Pages: |
1-16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3783411 |
Assay Type: |
Western blot |
Annotation Date: |
2008-04-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3783414 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Hc |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4821747 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-09-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4821750 |
Age: |
postnatal adult |
|
|
Specimen Label: |
HC |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5511025 |
Assay Type: |
Western blot |
Annotation Date: |
2013-10-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5511134 |
Age: |
postnatal adult |
Image: |
2 |
|
Specimen Label: |
HC |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5511025 |
Assay Type: |
Western blot |
Annotation Date: |
2013-10-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5511136 |
Age: |
postnatal adult |
Image: |
2 |
|
Specimen Label: |
HC |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5646598 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-08-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5648941 |
Age: |
postnatal |
Image: |
1 |
|
Specimen Label: |
Hc |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5646599 |
Assay Type: |
RT-PCR |
Annotation Date: |
2015-08-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5648944 |
Age: |
postnatal |
Image: |
1 |
|
Specimen Label: |
Hc |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7329761 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-08-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7329765 |
Age: |
postnatal day 30 |
Image: |
3 |
|
Specimen Label: |
Hc |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dung HC |
Year: |
1977 |
Journal: |
Transplantation |
Title: |
Deficiency in the thymus-dependent immunity in "lethargic" mutant mice. |
Volume: |
23 |
Issue: |
1 |
Pages: |
39-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones HC |
Year: |
1984 |
Journal: |
Z Kinderchir |
Title: |
The development of congenital hydrocephalus in the mouse. |
Volume: |
39 Suppl 2 |
|
Pages: |
87-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Towle HC |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Metabolic regulation of gene transcription in mammals. |
Volume: |
270 |
Issue: |
40 |
Pages: |
23235-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morse HC |
Year: |
1985 |
Journal: |
Mouse News Lett |
Title: |
Ly nomenclature registry. Rationalization of existing nomenclature |
Volume: |
72 |
|
Pages: |
21-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dung HC |
Year: |
1975 |
Journal: |
Anat Rec |
Title: |
Growth retardation, high mortality, and low reproductivity of neurological mutant mice. |
Volume: |
181 |
|
Pages: |
347-348 (Abstr.) |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Neill HC |
Year: |
1991 |
Journal: |
Arch Virol |
Title: |
Resistance to ectromelia virus infection in mice. Analysis of H-2-linked gene effects. |
Volume: |
118 |
Issue: |
3-4 |
Pages: |
253-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dung HC |
Year: |
1975 |
Journal: |
J Reprod Fertil |
Title: |
Evidence of prolactin cell deficiency in connection with low reproductive efficiency of female 'torpid' mice. |
Volume: |
45 |
Issue: |
1 |
Pages: |
91-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Slavkin HC |
Year: |
1993 |
Journal: |
Am J Med Genet |
Title: |
Rieger syndrome revisited: experimental approaches using pharmacologic and antisense strategies to abrogate EGF and TGF-alpha functions resulting in dysmorphogenesis during embryonic mouse craniofacial morphogenesis. |
Volume: |
47 |
Issue: |
5 |
Pages: |
689-97; discussion 687-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
380
![FASTA](model/images/fasta.gif;jsessionid=F20BD1E17882150885BDA8E531A7B515) |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
463
![FASTA](model/images/fasta.gif;jsessionid=F20BD1E17882150885BDA8E531A7B515) |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Dung HC |
Year: |
1981 |
|
Title: |
2. Lethargic mice |
Volume: |
2 |
|
Pages: |
17-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verma MK |
Year: |
2017 |
Journal: |
J Immunol Methods |
Title: |
A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo. |
Volume: |
446 |
|
Pages: |
47-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Howell GR |
Year: |
2013 |
Journal: |
J Neuroinflammation |
Title: |
Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice. |
Volume: |
10 |
|
Pages: |
76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joziasse DH |
Year: |
1991 |
Journal: |
Somat Cell Mol Genet |
Title: |
Gene for murine alpha 1----3-galactosyltransferase is located in the centromeric region of chromosome 2. |
Volume: |
17 |
Issue: |
2 |
Pages: |
201-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morse HC 3rd |
Year: |
1987 |
Journal: |
Immunogenetics |
Title: |
Genetic nomenclature for loci controlling mouse lymphocyte antigens. |
Volume: |
25 |
Issue: |
2 |
Pages: |
71-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hillebrandt S |
Year: |
2005 |
Journal: |
Nat Genet |
Title: |
Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans. |
Volume: |
37 |
Issue: |
8 |
Pages: |
835-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jackson HM |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
DBA/2J genetic background exacerbates spontaneous lethal seizures but lessens amyloid deposition in a mouse model of Alzheimer's disease. |
Volume: |
10 |
Issue: |
5 |
Pages: |
e0125897 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morse HC 3rd |
Year: |
1992 |
Journal: |
J Immunol |
Title: |
Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells. |
Volume: |
149 |
Issue: |
10 |
Pages: |
3129-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morse HC III |
Year: |
1995 |
Journal: |
Personal Communication to M. Davisson |
Title: |
Personal Communication - Spleen cells from CZECH II mice stain with mAb to Thy-1.1 |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Trendelenburg M |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
The role of complement in cryoglobulin-induced immune complex glomerulonephritis. |
Volume: |
175 |
Issue: |
10 |
Pages: |
6909-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schultz G |
Year: |
2010 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Enhanced abdominal aortic aneurysm formation in thrombin-activatable procarboxypeptidase B-deficient mice. |
Volume: |
30 |
Issue: |
7 |
Pages: |
1363-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson AL |
Year: |
2006 |
Journal: |
Infect Immun |
Title: |
Pathogenesis of B-cell superantigen-induced immune complex-mediated inflammation. |
Volume: |
74 |
Issue: |
2 |
Pages: |
1196-203 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stokol T |
Year: |
2004 |
Journal: |
J Exp Med |
Title: |
C1q governs deposition of circulating immune complexes and leukocyte Fcgamma receptors mediate subsequent neutrophil recruitment. |
Volume: |
200 |
Issue: |
7 |
Pages: |
835-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Subramaniam S |
Year: |
2017 |
Journal: |
Blood |
Title: |
Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development. |
Volume: |
129 |
Issue: |
16 |
Pages: |
2291-2302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Serra-Hassoun M |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
Human hematopoietic reconstitution and HLA-restricted responses in nonpermissive alymphoid mice. |
Volume: |
193 |
Issue: |
3 |
Pages: |
1504-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garcia S |
Year: |
1999 |
Journal: |
Immunity |
Title: |
Following the development of a CD4 T cell response in vivo: from activation to memory formation. |
Volume: |
11 |
Issue: |
2 |
Pages: |
163-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flynn S |
Year: |
2003 |
Journal: |
Blood |
Title: |
Tumor and CD4 T-cell interactions: tumor escape as result of reciprocal inactivation. |
Volume: |
101 |
Issue: |
11 |
Pages: |
4472-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wright RJ |
Year: |
1998 |
Journal: |
Immunology |
Title: |
The Ii41 isoform of invariant chain mediates both positive and negative selection events in T-cell receptor transgenic mice. |
Volume: |
95 |
Issue: |
3 |
Pages: |
309-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Szalai AJ |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Complement-dependent acute-phase expression of C-reactive protein and serum amyloid P-component. |
Volume: |
165 |
Issue: |
2 |
Pages: |
1030-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walbaum S |
Year: |
2021 |
Journal: |
J Biol Chem |
Title: |
Complement receptor 3 mediates both sinking phagocytosis and phagocytic cup formation via distinct mechanisms. |
Volume: |
296 |
|
Pages: |
100256 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karsten CM |
Year: |
2018 |
Journal: |
Front Immunol |
Title: |
Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2. |
Volume: |
9 |
|
Pages: |
488 |
|
•
•
•
•
•
|
Publication |
First Author: |
Binstadt BA |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The same systemic autoimmune disease provokes arthritis and endocarditis via distinct mechanisms. |
Volume: |
106 |
Issue: |
39 |
Pages: |
16758-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bersellini Farinotti A |
Year: |
2019 |
Journal: |
J Exp Med |
Title: |
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons. |
Volume: |
216 |
Issue: |
8 |
Pages: |
1904-1924 |
|
•
•
•
•
•
|
Publication |
First Author: |
Refici ML |
Year: |
2001 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Fcgamma-receptor signaling augments the LPS-stimulated increase in serum tumor necrosis factor-alpha levels. |
Volume: |
280 |
Issue: |
4 |
Pages: |
R1037-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sood R |
Year: |
2008 |
Journal: |
Blood |
Title: |
Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin. |
Volume: |
112 |
Issue: |
3 |
Pages: |
585-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun D |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Fungal dissemination is limited by liver macrophage filtration of the blood. |
Volume: |
10 |
Issue: |
1 |
Pages: |
4566 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baudino L |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens. |
Volume: |
111 |
Issue: |
4 |
Pages: |
1503-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolfe DN |
Year: |
2005 |
Journal: |
Infect Immun |
Title: |
Clearance of Bordetella parapertussis from the lower respiratory tract requires humoral and cellular immunity. |
Volume: |
73 |
Issue: |
10 |
Pages: |
6508-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pilione MR |
Year: |
2006 |
Journal: |
Cell Microbiol |
Title: |
CD11b is required for the resolution of inflammation induced by Bordetella bronchiseptica respiratory infection. |
Volume: |
8 |
Issue: |
5 |
Pages: |
758-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barthlott T |
Year: |
2001 |
Journal: |
Eur J Immunol |
Title: |
Lineage fate alteration of thymocytes developing in an MHC environment containing MHC/peptide ligands with antagonist properties. |
Volume: |
31 |
Issue: |
12 |
Pages: |
3595-601 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zal T |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function. |
Volume: |
93 |
Issue: |
17 |
Pages: |
9102-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mukai R |
Year: |
2018 |
Journal: |
Front Aging Neurosci |
Title: |
The Complement System Is Critical in Maintaining Retinal Integrity during Aging. |
Volume: |
10 |
|
Pages: |
15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu C |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling. |
Volume: |
201 |
Issue: |
12 |
Pages: |
3717-3730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ferreira C |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
Differential survival of naive CD4 and CD8 T cells. |
Volume: |
165 |
Issue: |
7 |
Pages: |
3689-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zal T |
Year: |
1994 |
Journal: |
J Exp Med |
Title: |
Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. |
Volume: |
180 |
Issue: |
6 |
Pages: |
2089-99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee HM |
Year: |
2010 |
Journal: |
Leukemia |
Title: |
Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes. |
Volume: |
24 |
Issue: |
3 |
Pages: |
573-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barthlott T |
Year: |
1998 |
Journal: |
J Immunol |
Title: |
Normal thymic selection of TCR transgenic CD4 T cells, but impaired survival in the periphery despite the presence of selecting MHC molecules. |
Volume: |
161 |
Issue: |
8 |
Pages: |
3992-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Müller-Calleja N |
Year: |
2018 |
Journal: |
Blood Adv |
Title: |
Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies. |
Volume: |
2 |
Issue: |
9 |
Pages: |
979-986 |
|
•
•
•
•
•
|
Publication |
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