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Search results 1 to 28 out of 28 for Mdm2

Category restricted to InteractionExperiment (x)

0.476s

Categories

Category: InteractionExperiment
« show all
Type Details Score
Interaction Experiment
Lee MH (2006)
Description: SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination.
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Interaction Experiment
Li X (2009)
Description: Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5.
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Interaction Experiment
Wang X (2011)
Description: MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
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Interaction Experiment
Clegg HV (2012)
Description: Mdm2 RING Mutation Enhances p53 Transcriptional Activity and p53-p300 Interaction.
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Interaction Experiment
Coutts AS (2007)
Description: Mdm2 targets the p53 transcription cofactor JMY for degradation.
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Interaction Experiment
Juven-Gershon T (1998)
Description: The Mdm2 oncoprotein interacts with the cell fate regulator Numb.
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Interaction Experiment
Yamauchi T (2014)
Description: MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24.
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Interaction Experiment
Hallenborg P (2016)
Description: MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3.
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Interaction Experiment
Tsai NP (2016)
Description: FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination.
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Interaction Experiment
Pant V (2011)
Description: Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.
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Interaction Experiment
Masuhara M (2003)
Description: Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.
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Interaction Experiment
Song MS (2008)
Description: The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex.
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Interaction Experiment
Tompkins VS (2007)
Description: A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability.
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Interaction Experiment
Alt JR (2005)
Description: Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
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Interaction Experiment
Lee D (2012)
Description: Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1.
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Interaction Experiment
Vlatkovic N (2000)
Description: MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase epsilon.
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Interaction Experiment
Dias SS (2009)
Description: Polo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnover.
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Interaction Experiment
Gu J (2002)
Description: Mutual dependence of MDM2 and MDMX in their functional inactivation of p53.
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Interaction Experiment
Reed SM (2014)
Description: Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53.
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Interaction Experiment
Fu D (2015)
Description: Mdm2 promotes myogenesis through the ubiquitination and degradation of CCAAT/enhancer-binding protein .
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Interaction Experiment
Wienken M (2016)
Description: MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53.
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Interaction Experiment
Malek R (2011)
Description: The p53 inhibitor MDM2 facilitates Sonic Hedgehog-mediated tumorigenesis and influences cerebellar foliation.
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Interaction Experiment
Michelsen K (2012)
Description: Ordering of the N-terminus of human MDM2 by small molecule inhibitors.
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Interaction Experiment
Itahana K (2007)
Description: Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation.
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Interaction Experiment
Giono LE (2007)
Description: Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest.
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Interaction Experiment
Picksley SM (1994)
Description: Immunochemical analysis of the interaction of p53 with MDM2;--fine mapping of the MDM2 binding site on p53 using synthetic peptides.
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Interaction Experiment
Knights CD (2003)
Description: Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification.
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Interaction Experiment
Girnita L (2005)
Description: {beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase.
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