|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1201 to 1300 out of 1371 for Ptk2

<< First    < Previous  |  Next >    Last >>
0.039s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:5302112
Age: embryonic day 12.5
Image: 3
Specimen Label: XY -/-
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301873
Assay Type: RT-PCR
Annotation Date: 2012-01-20
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5302112
Age: embryonic day 12.5
Image: 3
Specimen Label: XX +/+
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5302197
Assay Type: Western blot
Annotation Date: 2012-01-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5302412
Age: postnatal
Specimen Label: Not shown
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5313379
Assay Type: Western blot
Annotation Date: 2012-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5313441
Age: embryonic day 8.5
Specimen Label: FAK+/+p53+/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5313379
Assay Type: Western blot
Annotation Date: 2012-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5313441
Age: embryonic day 8.5
Specimen Label: FAK+/-p53+/+
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5313379
Assay Type: Western blot
Annotation Date: 2012-03-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:5313441
Age: embryonic day 8.5
Specimen Label: FAK-/-p53+/+
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6383968
Assay Type: Western blot
Annotation Date: 2020-01-09
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:6383972
Age: postnatal adult
Image: 1
Specimen Label: MII oocytes
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6383971
Assay Type: RT-PCR
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:6383973
Age: embryonic day 0.5
Image: 1
Specimen Label: 1-cell
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6383971
Assay Type: RT-PCR
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:6383973
Age: embryonic day 1.0
Image: 1
Specimen Label: 2-cell
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6383971
Assay Type: RT-PCR
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:6383973
Age: embryonic day 2.0
Image: 1
Specimen Label: 4-cell
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7429224
Assay Type: Western blot
Annotation Date: 2023-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:7430760
Age: embryonic day 14.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7429224
Assay Type: Western blot
Annotation Date: 2023-01-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:7430760
Age: embryonic day 14.5
Specimen Label: delta/delta
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383975
Age: embryonic day 2.0
Image: 3C2/C
Note: Expression in nucleus and cytoplasm. Expression uniformly distributed throughout cytoplasm.
Specimen Label: 3C2/C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383976
Age: embryonic day 2.0
Image: 4B2/B
Note: Expression increasingly weakened until the morula stage. Expression throughout cytoplasm. Punctate distribution of expression, presented as many points or peaches.
Specimen Label: 4B2/B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Regionally restricted
Stage: TS01
Assay Id: MGI:6383975
Age: embryonic day 0.5
Image: 3A2/A
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3A2/A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383975
Age: embryonic day 2.5
Image: 3D2/D
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3D2/D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383976
Age: embryonic day 2.5
Image: 4C2/C
Note: Expression increasingly weakened until the morula stage. Expression throughout cytoplasm. Punctate distribution of expression, presented as many points or peaches.
Specimen Label: 4C2/C
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:2909820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5302047
Age: embryonic day 12.5
Image: 1D XY 12.5
Note: Expression was restricted to the testis cords.
Specimen Label: 1D XY 12.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:2909821
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 1D XY 13.5
Note: Expression was restricted to the testis cords.
Specimen Label: 1D XY 13.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Strong
Sex: Male
Emaps: EMAPS:2909821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302231
Age: embryonic day 13.5
Image: 4B
Specimen Label: 4B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5302231
Age: postnatal
Specimen Label: not shown
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Male
Emaps: EMAPS:1685717
Stage: TS17
Assay Id: MGI:5302047
Age: embryonic day 10.5
Image: 1D XY 10.5
Specimen Label: 1D XY 10.5
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1685717
Stage: TS17
Assay Id: MGI:5302047
Age: embryonic day 10.5
Image: 1D XX 10.5
Specimen Label: 1D XX 10.5
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383975
Age: embryonic day 3.5
Image: 3G2/G
Note: No expression in cell nuclei. Expression distributed throughout cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3G2/G
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360355
Pattern: Regionally restricted
Stage: TS05
Assay Id: MGI:6383975
Age: embryonic day 4.0
Image: 3H2/H
Note: No expression in cell nuclei. Expression distributed throughout cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots. Expression in gaps of trophoblast cells.
Specimen Label: 3H2/H
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383976
Age: embryonic day 3.5
Image: 4E2/E
Note: Expression in perinuclear region and joint of cells. No expression in nuclei.
Specimen Label: 4E2/E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Regionally restricted
Stage: TS03
Assay Id: MGI:6383975
Age: embryonic day 3.0
Image: 3E2/E
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3E2/E
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383975
Age: embryonic day 3.0
Image: 3F2/F
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.
Specimen Label: 3F2/F
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Regionally restricted
Stage: TS04
Assay Id: MGI:6383976
Age: embryonic day 3.0
Image: 4D2/D
Note: Expression increasingly weakened until the morula stage. Expression in the perinuclear region.
Specimen Label: 4D2/D
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Present
Sex: Male
Emaps: EMAPS:1797221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5302231
Age: embryonic day 13.5
Image: 4B
Note: High expression levels within in somatic cells of the testis cords.
Specimen Label: 4B
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Absent
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:5302231
Age: embryonic day 12.5
Specimen Label: not shown
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383968
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6383975
Age: embryonic day 1.0
Image: 3B2/B
Note: Expression in nucleus and cytoplasm. Expression in cytoplasm not evenly distributed, but aggregated as many tiny spots.Expression also detected in cell junctions.
Specimen Label: 3B2/B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6383970
Assay Type: Immunohistochemistry
Annotation Date: 2020-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Regionally restricted
Stage: TS02
Assay Id: MGI:6383976
Age: embryonic day 1.0
Image: 4A2/A
Note: Expression particularly in joints of the two cells and this nuclei, but not in nucleoli.
Specimen Label: 4A2/A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5302047
Age: embryonic day 11.5
Image: 1D XY 11.5
Note: Expressed in the genital ridges.
Specimen Label: 1D XY 11.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5302047
Age: embryonic day 11.5
Image: 1D XX 11.5
Specimen Label: 1D XX 11.5
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5302047
Age: embryonic day 12.5
Image: 1D XX 12.5
Specimen Label: 1D XX 12.5
Detected: false
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5301887
Assay Type: RNA in situ
Annotation Date: 2012-01-19
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5302047
Age: embryonic day 13.5
Image: 1D XX 13.5
Specimen Label: 1D XX 13.5
Detected: false
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5302197
Assay Type: Immunohistochemistry
Annotation Date: 2012-01-20
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5302231
Age: embryonic day 13.5
Image: 4D
Specimen Label: 4D
Detected: false
Specimen Num: 2
•
•
•
•
•
Protein Coding Gene
MGI:109321 | Lama4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
P97927
Organism: Mus musculus/domesticus
Length: 1816  
Fragment?: false
•
•
•
•
•
Allele
Gt(ROSA)26Sor<tm5(PTK2*Y397E*K454R)Khd> | MGI:5704298
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Kairbaan M Hodivala-Dilke
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
•
•
•
•
•
Allele
Gt(ROSA)26Sor<tm4(PTK2*K454R)Khd> | MGI:5704296
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Kairbaan M Hodivala-Dilke
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
•
•
•
•
•
Strain
MGI:3689882 | CBA.Cg-Ptk2<tm1Imeg>
Attribute String: congenic, mutant strain, targeted mutation
•
•
•
•
•
Strain
MGI:3821926 | B6.129P2-Ptk2<tm1.1Jtpa>
Attribute String: congenic, targeted mutation
•
•
•
•
•
Strain
MGI:3783258 | B6.Cg-Ptk2<tm1Mmsh> Tg(Nes-cre)1Sasa
Attribute String: congenic, targeted mutation, transgenic
•
•
•
•
•
Strain
MGI:4839934 | B6;129X1-Ptk2<tm1Lfr>/Mmucd
Attribute String: targeted mutation, mutant stock
•
•
•
•
•
Strain
MGI:7469305 | C57BL/6JGpt-Ptk2<em2Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Strain
MGI:7469307 | C57BL/6JGpt-Ptk2b<em4Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Strain
MGI:7570658 | C57BL/6N-Ptk2b<em1(IMPC)Wtsi>/WtsiIeg
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Strain
MGI:6335226 | C57BL/6N-Ptk2b<em1(IMPC)Wtsi>/Wtsi
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Strain
MGI:7592912 | C57BL/6J-Ptk2b<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Strain
MGI:6771089 | C57BL/6J-Ptk2b<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Strain
MGI:7469306 | C57BL/6JGpt-Ptk2b<em3Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2b/Ptk2b
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: CBA.Cg-Ptk2
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2 Tg(Tek-cre)1Rwng/?
Background: involves: 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2 Tg(Nes-cre)1Sasa/?
Background: B6.Cg-Ptk2 Tg(Nes-cre)1Sasa
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2b/Ptk2b
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: B6.129P2-Ptk2
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2 Tg(Tek-cre)12Flv/?
Background: involves: 129P2/OlaHsd * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: involves: 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: involves: 129S/SvEv * C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2 Tg(MMTV-PyVT)634Mul/?
Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2b/Ptk2b
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2b/Ptk2b
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2
Background: involves: 129X1/SvJ * CD-1
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2b/Ptk2b
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Publication
34529077 | J:326577
First Author: Zheng J
Year: 2022
Journal: J Mol Cell Biol
Title: Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Volume: 13
Issue: 11
Pages: 808-821
•
•
•
•
•
Publication
25349423 | J:216771
First Author: Kinoshita Y
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role for NUP62 depletion and PYK2 redistribution in dendritic retraction resulting from chronic stress.
Volume: 111
Issue: 45
Pages: 16130-5
•
•
•
•
•
Publication
29911975 | J:264145
   
First Author: Fan L
Year: 2018
Journal: Elife
Title: Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
Volume: 7
•
•
•
•
•
Protein Coding Gene
MGI:96602 | Itga3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI:96600 | Itga2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein
Q62469
Organism: Mus musculus/domesticus
Length: 1178  
Fragment?: false
•
•
•
•
•
Protein
Q62470
Organism: Mus musculus/domesticus
Length: 1053  
Fragment?: false
•
•
•
•
•
Strain
MGI:6344787 | C57BL/6N-A<tm1Brd> Ptk2<tm1a(KOMP)Wtsi>/MbpMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2 Tg(KRT14-cre/ERT2)1Ipc/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2<+>
Background: involves: 129S/SvEv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Ptk2/Ptk2<+>
Background: involves: 129/Sv * C57BL/6
Zygosity: ht
Has Mutant Allele: true
•
•
•
•
•
Publication
12771146 | J:230354
First Author: Kruljac-Letunic A
Year: 2003
Journal: J Biol Chem
Title: The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1.
Volume: 278
Issue: 32
Pages: 29560-70
•
•
•
•
•
Publication
7499242 | J:29773
First Author: Avraham S
Year: 1995
Journal: J Biol Chem
Title: Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain.
Volume: 270
Issue: 46
Pages: 27742-51
•
•
•
•
•
Publication
11238453 | J:67886
First Author: Ren XR
Year: 2001
Journal: J Cell Biol
Title: Regulation of CDC42 GTPase by proline-rich tyrosine kinase 2 interacting with PSGAP, a novel pleckstrin homology and Src homology 3 domain containing rhoGAP protein.
Volume: 152
Issue: 5
Pages: 971-84
•
•
•
•
•
Publication
14739300 | J:89495
First Author: Miyazaki T
Year: 2004
Journal: J Biol Chem
Title: Src kinase activity is essential for osteoclast function.
Volume: 279
Issue: 17
Pages: 17660-6
•
•
•
•
•
Publication
26642240 | J:231935
First Author: Jabara HH
Year: 2016
Journal: Nat Genet
Title: A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Volume: 48
Issue: 1
Pages: 74-8
•
•
•
•
•
Publication
20727793 | J:163910
First Author: Davidson D
Year: 2010
Journal: Immunity
Title: The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2.
Volume: 33
Issue: 2
Pages: 167-80
•
•
•
•
•
Publication
22544749 | J:186506
First Author: Xu J
Year: 2012
Journal: J Biol Chem
Title: Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.
Volume: 287
Issue: 25
Pages: 20942-56
•
•
•
•
•
Publication
28385807 | J:243304
First Author: Soni D
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca2+ entry regulates disassembly of adherens junctions.
Volume: 312
Issue: 6
Pages: L1003-L1017
•
•
•
•
•
Publication
23589331 | J:204493
First Author: Rhee I
Year: 2013
Journal: Mol Cell Biol
Title: Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/PTPN12.
Volume: 33
Issue: 12
Pages: 2458-69
•
•
•
•
•
Publication
11274221 | J:79952
First Author: Andreev J
Year: 2001
Journal: J Biol Chem
Title: Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade.
Volume: 276
Issue: 23
Pages: 20130-5
•
•
•
•
•
Publication
9988732 | J:53091
First Author: Lakkakorpi PT
Year: 1999
Journal: J Biol Chem
Title: Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone.
Volume: 274
Issue: 8
Pages: 4900-7
•
•
•
•
•
Publication
15761030 | J:99228
First Author: Sekimoto H
Year: 2005
Journal: Mol Endocrinol
Title: (alpha)v(beta)3 integrins and Pyk2 mediate insulin-like growth factor I activation of Src and mitogen-activated protein kinase in 3T3-L1 cells.
Volume: 19
Issue: 7
Pages: 1859-67
•
•
•
•
•
Publication
16546139 | J:107563
First Author: Guignandon A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Cyclic strain promotes shuttling of PYK2/Hic-5 complex from focal contacts in osteoblast-like cells.
Volume: 343
Issue: 2
Pages: 407-14
•
•
•
•
•
Publication
17684059 | J:128374
First Author: Faure C
Year: 2007
Journal: J Cell Sci
Title: Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons.
Volume: 120
Issue: Pt 17
Pages: 3034-44
•
•
•
•
•
Publication
19380485 | J:149899
First Author: Bruzzaniti A
Year: 2009
Journal: Mol Cell Biol
Title: Dynamin reduces Pyk2 Y402 phosphorylation and SRC binding in osteoclasts.
Volume: 29
Issue: 13
Pages: 3644-56
•
•
•
•
•
Publication
18483407 | J:151384
First Author: Fisslthaler B
Year: 2008
Journal: Circ Res
Title: Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin.
Volume: 102
Issue: 12
Pages: 1520-8
•
•
•
•
•
Publication
19841181 | J:157191
First Author: Pierau M
Year: 2009
Journal: J Immunol
Title: Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation.
Volume: 183
Issue: 10
Pages: 6124-34
•
•
•
•
•
Publication
23711511 | J:202540
First Author: Martel-Gallegos G
Year: 2013
Journal: Biochim Biophys Acta
Title: Oxidative stress induced by P2X7 receptor stimulation in murine macrophages is mediated by c-Src/Pyk2 and ERK1/2.
Volume: 1830
Issue: 10
Pages: 4650-9
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom