|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 175 out of 175 for Hells

<< First    < Previous  |  Next >    Last >>
0.023s

Categories

Hits by Strain

Hits by Category

Type Details Score
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_692149
Specimen Label: HMGU_692149
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3584856
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3586173
Age: embryonic day 16.0
Image: E16
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E16
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_692147
Specimen Label: HMGU_692147
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_1366550
Specimen Label: HMGU_1366550
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_692151
Specimen Label: HMGU_692151
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_1366553
Specimen Label: HMGU_1366553
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_692155
Specimen Label: HMGU_692155
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_1366548
Specimen Label: HMGU_1366548
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691057
Age: postnatal adult
Image: HMGU_1366552
Specimen Label: HMGU_1366552
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:3584856
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3586173
Age: embryonic day 14.0
Image: E14
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
12471446 | J:81663
First Author: Yan L
Year: 2002
Journal: Mol Genet Genomics
Title: Cereal genes similar to Snf2 define a new subfamily that includes human and mouse genes.
Volume: 268
Issue: 4
Pages: 488-99
•
•
•
•
•
Publication
21427231 | J:171223
First Author: Tao Y
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences.
Volume: 108
Issue: 14
Pages: 5626-31
•
•
•
•
•
Publication
20161795 | J:223631
First Author: Tao Y
Year: 2010
Journal: PLoS One
Title: Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation.
Volume: 5
Issue: 2
Pages: e9163
•
•
•
•
•
Publication
8647447 | J:32111
First Author: Jarvis CD
Year: 1996
Journal: Gene
Title: A novel putative helicase produced in early murine lymphocytes.
Volume: 169
Issue: 2
Pages: 203-7
•
•
•
•
•
Publication
22946062 | J:200281
First Author: Burrage J
Year: 2012
Journal: J Cell Sci
Title: The SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells.
Volume: 125
Issue: Pt 22
Pages: 5524-34
•
•
•
•
•
Publication
33159050 | J:299841
First Author: Ni K
Year: 2020
Journal: Nat Commun
Title: LSH mediates gene repression through macroH2A deposition.
Volume: 11
Issue: 1
Pages: 5647
•
•
•
•
•
Publication
16395332 | J:200300
First Author: Zhu H
Year: 2006
Journal: EMBO J
Title: Lsh is involved in de novo methylation of DNA.
Volume: 25
Issue: 2
Pages: 335-45
•
•
•
•
•
Publication
15647320 | J:96925
First Author: Fan T
Year: 2005
Journal: Development
Title: Lsh controls silencing of the imprinted Cdkn1c gene.
Volume: 132
Issue: 4
Pages: 635-44
•
•
•
•
•
Publication
38335290 | J:345314
First Author: Vukic M
Year: 2024
Journal: Sci Adv
Title: CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses.
Volume: 10
Issue: 6
Pages: eadk3384
•
•
•
•
•
Publication
15448183 | J:93871
First Author: Huang J
Year: 2004
Journal: Nucleic Acids Res
Title: Lsh, an epigenetic guardian of repetitive elements.
Volume: 32
Issue: 17
Pages: 5019-28
•
•
•
•
•
Publication
28442710 | J:275323
First Author: Han Y
Year: 2017
Journal: Sci Rep
Title: Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells.
Volume: 7
Issue: 1
Pages: 1136
•
•
•
•
•
Publication
20439742 | J:160567
First Author: Velasco G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues.
Volume: 107
Issue: 20
Pages: 9281-6
•
•
•
•
•
Publication
15105378 | J:107145
First Author: Sun LQ
Year: 2004
Journal: Genes Dev
Title: Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG.
Volume: 18
Issue: 9
Pages: 1035-46
•
•
•
•
•
Publication
17726103 | J:248225
First Author: Xi S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Lsh controls Hox gene silencing during development.
Volume: 104
Issue: 36
Pages: 14366-71
•
•
•
•
•
Publication
22516201 | J:183999
First Author: Ouseph MM
Year: 2012
Journal: Dev Cell
Title: Atypical E2F repressors and activators coordinate placental development.
Volume: 22
Issue: 4
Pages: 849-62
•
•
•
•
•
Publication
11555636 | J:71817
First Author: Sutherland HG
Year: 2001
Journal: Hum Mol Genet
Title: Large-scale identification of mammalian proteins localized to nuclear sub-compartments.
Volume: 10
Issue: 18
Pages: 1995-2011
•
•
•
•
•
Publication
31493975 | J:282593
First Author: Norrie JL
Year: 2019
Journal: Neuron
Title: Nucleome Dynamics during Retinal Development.
Volume: 104
Issue: 3
Pages: 512-528.e11
•
•
•
•
•
Publication
20439489 | J:163558
First Author: Tarantino C
Year: 2010
Journal: FASEB J
Title: miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells.
Volume: 24
Issue: 9
Pages: 3255-63
•
•
•
•
•
Publication
- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
•
•
•
•
•
Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
•
•
•
•
•
Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
•
•
•
•
•
Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
•
•
•
•
•
Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
•
•
•
•
•
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
HT Experiment
GSE144427 | Transcriptome analysis of Chx10-Cre Rb1/p107 and Chx10-Cre Rb1/p107/Hells P21 retinae
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
DO Term
DOID:0090011 | immunodeficiency-centromeric instability-facial anomalies syndrome 4
•
•
•
•
•
Publication
25351940 | -
First Author: Choi YJ
Year: 2015
Journal: Pathol Oncol Res
Title: Mutation of HELLS, a chromatin remodeling gene, gastric and colorectal cancers.
Volume: 21
Issue: 3
Pages: 851-2
•
•
•
•
•
Publication
12403775 | -
First Author: Brzeski J
Year: 2003
Journal: J Biol Chem
Title: Deficient in DNA methylation 1 (DDM1) defines a novel family of chromatin-remodeling factors.
Volume: 278
Issue: 2
Pages: 823-8
•
•
•
•
•
Publication
11948614 | -
First Author: Bourc'his D
Year: 2002
Journal: Bioessays
Title: Helicase homologues maintain cytosine methylation in plants and mammals.
Volume: 24
Issue: 4
Pages: 297-9
•
•
•
•
•
Protein Domain
IPR044753 | HELLS_N
Type: Domain
Description: HELLS (helicase, lymphoid specific, also known as Lsh or SMARCA6) is a major epigenetic regulator crucial for normal heterochromatin structure and function []. HELLS is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding []. This domain contains the ATP-binding region. Proteins containing this domain also includes Irc5 from budding yeasts and DDM1 from Arabidopsis. DDM1 acts as a chromatin-remodeling factor required for the maintenance of genomic methylation [, ].
•
•
•
•
•
Publication
27466202 | J:238568
First Author: Wu H
Year: 2016
Journal: Hum Mol Genet
Title: Converging disease genes in ICF syndrome: ZBTB24 controls expression of CDCA7 in mammals.
Volume: 25
Issue: 18
Pages: 4041-4051
•
•
•
•
•
Publication
21779027 | -
First Author: Linder P
Year: 2011
Journal: Nat Rev Mol Cell Biol
Title: From unwinding to clamping - the DEAD box RNA helicase family.
Volume: 12
Issue: 8
Pages: 505-16
•
•
•
•
•
Protein
Q60848
Organism: Mus musculus/domesticus
Length: 821  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom