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Search results 301 to 341 out of 341 for Bmp1

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Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
UniProt Feature
Begin: 277
Description: Cleavage; by BMP1
Type: site
End: 278
UniProt Feature
Begin: 22
Description: Removed by BMP1
Type: propeptide
End: 162
UniProt Feature
Begin: 3513
Description: Cleavage; by BMP1
Type: site
End: 3514
Publication
First Author: Rosell-GarcĂ­a T
Year: 2019
Journal: J Biol Chem
Title: Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.
Volume: 294
Issue: 29
Pages: 11087-11100
Publication
First Author: Valencia M
Year: 2014
Journal: Am J Med Genet A
Title: Report of a newly indentified patient with mutations in BMP1 and underlying pathogenetic aspects.
Volume: 164A
Issue: 5
Pages: 1143-50
Allele
Name: bone morphogenetic protein 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
DO Term
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: bone morphogenetic protein 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Allele
Name: transgene insertion IL335, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Li SW
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1.
Volume: 93
Issue: 10
Pages: 5127-30
Publication
First Author: Prockop DJ
Year: 1998
Journal: Matrix Biol
Title: Procollagen N-proteinase and procollagen C-proteinase. Two unusual metalloproteinases that are essential for procollagen processing probably have important roles in development and cell signaling.
Volume: 16
Issue: 7
Pages: 399-408
Publication
First Author: Medeck RJ
Year: 2003
Journal: Biochem J
Title: BMP-1-mediated proteolytic processing of alternatively spliced isoforms of collagen type XI.
Volume: 376
Issue: Pt 2
Pages: 361-8
Publication  
First Author: Anastasi C
Year: 2020
Journal: Sci Signal
Title: BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1.
Volume: 13
Issue: 639
Publication
First Author: Wang J
Year: 2021
Journal: J Periodontol
Title: Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.
Volume: 92
Issue: 7
Pages: 1018-1029
Protein Domain
Type: Family
Description: Bone morphogenetic protein 1 (BMP1) is a member of the astacin family (MEROPS family M12A) of metalloproteinases which plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins []. During ECM formation, this protein is involved in the cleavage of the C-terminal propeptides of procollagen I, II and III and the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers [, , ]. BMP1 participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair[, ]. BMP1 is essential for human type I collagen fibrillogenesis []and induces cartilage and bone formation [, ]. Additional BMP1 substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation [].
Publication
First Author: Ge G
Year: 2006
Journal: Birth Defects Res C Embryo Today
Title: Developmental roles of the BMP1/TLD metalloproteinases.
Volume: 78
Issue: 1
Pages: 47-68
Publication
First Author: Sarras MP Jr
Year: 1996
Journal: Bioessays
Title: BMP-1 and the astacin family of metalloproteinases: a potential link between the extracellular matrix, growth factors and pattern formation.
Volume: 18
Issue: 6
Pages: 439-42
Publication
First Author: Mullins MC
Year: 1998
Journal: Trends Genet
Title: Holy Tolloido: Tolloid cleaves SOG/Chordin to free DPP/BMPs.
Volume: 14
Issue: 4
Pages: 127-9
Protein Domain
Type: Domain
Description: This entry includes the zinc-dependent metalloprotease domain of BMP1 and tolloid-like proteins. Procollagen C-peptidase (BMP1, Bone morphogenetic protein 1; MEROPS identifier M12.005) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, and proteins involved in the mineralization of the extracellular matrix. The Drosophila protein tolloid (MEROPS identifier M12.010) and its Xenopus homologue xolloid (MEROPS identifier M12.015) cleave and inactivate Sog and chordin, respectively, which are inhibitors of Dpp (the Drosophila decapentaplegic gene product) and its homologue BMP4, involved in dorso-ventral patterning[, , ].
Publication
First Author: Ng D
Year: 2009
Journal: PLoS Biol
Title: Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.
Volume: 7
Issue: 2
Pages: e41
Publication
First Author: Zhu Q
Year: 2012
Journal: Connect Tissue Res
Title: Partial blocking of mouse DSPP processing by substitution of Gly(451)-Asp(452) bond suggests the presence of secondary cleavage site(s).
Volume: 53
Issue: 4
Pages: 307-12
Publication
First Author: Borazjani A
Year: 2019
Journal: Biol Reprod
Title: Role of lysyl oxidase like 1 in regulation of postpartum connective tissue metabolism in the mouse vagina†.
Volume: 101
Issue: 5
Pages: 916-927
Publication
First Author: He W
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.
Volume: 107
Issue: 49
Pages: 21110-5
Publication
First Author: Harlow CR
Year: 2017
Journal: PLoS One
Title: Targeting lysyl oxidase reduces peritoneal fibrosis.
Volume: 12
Issue: 8
Pages: e0183013
Protein
Organism: Mus musculus/domesticus
Length: 775  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 991  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1012  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data