Type |
Details |
Score |
Genotype |
Symbol: |
Tg(KRT5-IKBKB)2Armz/? |
Background: |
involves: C57BL/6 * DBA/2 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ighg1/Ighg1<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Twist2/Twist2<+> |
Background: |
involves: 129X1/SvJ * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Xing Y |
Year: |
2016 |
Journal: |
Nat Immunol |
Title: |
Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling. |
Volume: |
17 |
Issue: |
5 |
Pages: |
565-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lei Z |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
NF-κB Activation Accounts for the Cytoprotective Effects of PERK Activation on Oligodendrocytes during EAE. |
Volume: |
40 |
Issue: |
33 |
Pages: |
6444-6456 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tichy ED |
Year: |
2021 |
Journal: |
STAR Protoc |
Title: |
Telomere length assessments of muscle stem cells in rodent and human skeletal muscle sections. |
Volume: |
2 |
Issue: |
4 |
Pages: |
100830 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mussbacher M |
Year: |
2024 |
Journal: |
Cells |
Title: |
Effects of Chronic Inflammatory Activation of Murine and Human Arterial Endothelial Cells at Normal Lipoprotein and Cholesterol Levels In Vivo and In Vitro. |
Volume: |
13 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kometani K |
Year: |
2011 |
Journal: |
J Exp Med |
Title: |
CIN85 drives B cell responses by linking BCR signals to the canonical NF-kappaB pathway. |
Volume: |
208 |
Issue: |
7 |
Pages: |
1447-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finkin S |
Year: |
2015 |
Journal: |
Nat Immunol |
Title: |
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma. |
Volume: |
16 |
Issue: |
12 |
Pages: |
1235-44 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ikbkb/Ikbkb Tnfrsf1a/Tnfrsf1a |
Background: |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Chuk/Chuk Ikbkb/Ikbkb |
Background: |
involves: 129S4/SvJae * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Chuk/Chuk Ikbkb/Ikbkb Tnfrsf1a/Tnfrsf1a |
Background: |
involves: 129/Sv * 129S4/SvJae * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cd19/Cd19<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tnfrsf13c/Tnfrsf13c |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Sh3kbp1/Sh3kbp1 Cd79a/Cd79a<+> Gt(ROSA)26Sor/? |
Background: |
involves: BALB/c * C57BL/6 * NZB |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ighg1/Ighg1<+> Prdm1/Prdm1 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Tagln-cre)1Her/? |
Background: |
involves: C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Pascual M |
Year: |
2019 |
Journal: |
Blood |
Title: |
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas. |
Volume: |
133 |
Issue: |
22 |
Pages: |
2401-2412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koerner L |
Year: |
2023 |
Journal: |
Cell Death Differ |
Title: |
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer. |
Volume: |
30 |
Issue: |
4 |
Pages: |
938-951 |
|
•
•
•
•
•
|
Publication |
First Author: |
Page A |
Year: |
2011 |
Journal: |
Mol Cancer Res |
Title: |
IKKβ overexpression leads to pathologic lesions in stratified epithelia and exocrine glands and to tumoral transformation of oral epithelia. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1329-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shan B |
Year: |
2020 |
Journal: |
Nat Metab |
Title: |
Perivascular mesenchymal cells control adipose-tissue macrophage accrual in obesity. |
Volume: |
2 |
Issue: |
11 |
Pages: |
1332-1349 |
|
•
•
•
•
•
|
Publication |
First Author: |
Page A |
Year: |
2020 |
Journal: |
Int J Oral Sci |
Title: |
IKKβ overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice. |
Volume: |
12 |
Issue: |
1 |
Pages: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fuller DM |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
The importance of the Erk pathway in the development of linker for activation of T cells-mediated autoimmunity. |
Volume: |
189 |
Issue: |
8 |
Pages: |
4005-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang Y |
Year: |
2021 |
Journal: |
J Cereb Blood Flow Metab |
Title: |
Cerebral angiogenesis ameliorates pathological disorders in Nemo-deficient mice with small-vessel disease. |
Volume: |
41 |
Issue: |
2 |
Pages: |
219-235 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tichy ED |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Persistent NF-κB activation in muscle stem cells induces proliferation-independent telomere shortening. |
Volume: |
35 |
Issue: |
6 |
Pages: |
109098 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sasaki Y |
Year: |
2006 |
Journal: |
Immunity |
Title: |
Canonical NF-kappaB activity, dispensable for B cell development, replaces BAFF-receptor signals and promotes B cell proliferation upon activation. |
Volume: |
24 |
Issue: |
6 |
Pages: |
729-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen Y |
Year: |
2021 |
Journal: |
PLoS Genet |
Title: |
NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1. |
Volume: |
17 |
Issue: |
11 |
Pages: |
e1009933 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schlett JS |
Year: |
2023 |
Journal: |
Mol Neurodegener |
Title: |
NF-κB is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss. |
Volume: |
18 |
Issue: |
1 |
Pages: |
24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winkler W |
Year: |
2023 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mouse models of human multiple myeloma subgroups. |
Volume: |
120 |
Issue: |
10 |
Pages: |
e2219439120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin HY |
Year: |
2016 |
Journal: |
Leukemia |
Title: |
Concurrent PI3K and NF-κB activation drives B-cell lymphomagenesis. |
Volume: |
30 |
Issue: |
11 |
Pages: |
2267-2270 |
|
•
•
•
•
•
|
Publication |
First Author: |
Botta C |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance. |
Volume: |
14 |
Issue: |
1 |
Pages: |
5825 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Analysis of GzmbCre as a Model System for Gene Deletion in the Natural Killer Cell Lineage. |
Volume: |
10 |
Issue: |
4 |
Pages: |
e0125211 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCoy AM |
Year: |
2017 |
Journal: |
Am J Pathol |
Title: |
IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis. |
Volume: |
187 |
Issue: |
12 |
Pages: |
2635-2644 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor Igh-J/? Igh/? Tg(Cr2-cre)3Cgn/? |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang C |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells. |
Volume: |
7 |
Issue: |
1 |
Pages: |
4880 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen S |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
Tight regulation of diacylglycerol-mediated signaling is critical for proper invariant NKT cell development. |
Volume: |
187 |
Issue: |
5 |
Pages: |
2122-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Molinero LL |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
High TCR stimuli prevent induced regulatory T cell differentiation in a NF-κB-dependent manner. |
Volume: |
186 |
Issue: |
8 |
Pages: |
4609-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakagawa MM |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells. |
Volume: |
25 |
Issue: |
8 |
Pages: |
2094-2109.e4 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
757
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
738
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
707
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
745
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
719
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
671
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
745
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
745
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
745
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
719
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
719
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao D |
Year: |
2023 |
Journal: |
J Clin Invest |
Title: |
DNA methylation-mediated Rbpjk suppression protects against fracture nonunion caused by systemic inflammation. |
Volume: |
134 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jong Huat T |
Year: |
2024 |
Journal: |
Sci Rep |
Title: |
The impact of astrocytic NF-κB on healthy and Alzheimer's disease brains. |
Volume: |
14 |
Issue: |
1 |
Pages: |
14305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kondylis V |
Year: |
2015 |
Journal: |
Cancer Cell |
Title: |
NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis. |
Volume: |
28 |
Issue: |
5 |
Pages: |
582-598 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miller ML |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cells. |
Volume: |
111 |
Issue: |
20 |
Pages: |
7397-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2015 |
Journal: |
Immunity |
Title: |
MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism. |
Volume: |
43 |
Issue: |
2 |
Pages: |
289-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenbaum M |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2352 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dannappel M |
Year: |
2014 |
Journal: |
Nature |
Title: |
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. |
Volume: |
513 |
Issue: |
7516 |
Pages: |
90-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Myant KB |
Year: |
2013 |
Journal: |
Cell Stem Cell |
Title: |
ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation. |
Volume: |
12 |
Issue: |
6 |
Pages: |
761-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Srinivasan L |
Year: |
2009 |
Journal: |
Cell |
Title: |
PI3 kinase signals BCR-dependent mature B cell survival. |
Volume: |
139 |
Issue: |
3 |
Pages: |
573-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|