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Search results 1 to 100 out of 185 for F8

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Type Details Score
Publication
31843008 | J:285277
First Author: Zhang JP
Year: 2019
Journal: Genome Biol
Title: Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse.
Volume: 20
Issue: 1
Pages: 276
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Publication
26588198 | J:266699
First Author: Chao BN
Year: 2016
Journal: J Thromb Haemost
Title: Characterization of a genetically engineered mouse model of hemophilia A with complete deletion of the F8 gene.
Volume: 14
Issue: 2
Pages: 346-55
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Publication
34290295 | J:313828
First Author: Hayakawa M
Year: 2021
Journal: Sci Rep
Title: Characterization and visualization of murine coagulation factor VIII-producing cells in vivo.
Volume: 11
Issue: 1
Pages: 14824
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Publication
21705497 | J:176909
First Author: van Helden PM
Year: 2011
Journal: Blood
Title: Maintenance and break of immune tolerance against human factor VIII in a new transgenic hemophilic mouse model.
Volume: 118
Issue: 13
Pages: 3698-707
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Publication
20852129 | J:167399
First Author: Greene TK
Year: 2010
Journal: Blood
Title: In vivo efficacy of platelet-delivered, high specific activity factor VIII variants.
Volume: 116
Issue: 26
Pages: 6114-22
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Publication
24719406 | J:213133
First Author: Everett LA
Year: 2014
Journal: Blood
Title: Murine coagulation factor VIII is synthesized in endothelial cells.
Volume: 123
Issue: 24
Pages: 3697-705
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Publication
28827327 | J:244506
First Author: Westrick RJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.
Volume: 114
Issue: 36
Pages: 9659-9664
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Publication
8314577 | J:4959
First Author: Elder B
Year: 1993
Journal: Genomics
Title: Sequence of the murine factor VIII cDNA.
Volume: 16
Issue: 2
Pages: 374-9
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Publication
22368271 | J:186576
First Author: Follenzi A
Year: 2012
Journal: Blood
Title: Role of bone marrow transplantation for correcting hemophilia A in mice.
Volume: 119
Issue: 23
Pages: 5532-42
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Publication
7647782 | J:24941
First Author: Bi L
Year: 1995
Journal: Nat Genet
Title: Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.
Volume: 10
Issue: 1
Pages: 119-21
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Publication
19463774 | J:151239
First Author: Ragni MV
Year: 2009
Journal: Exp Hematol
Title: Factor VIII-pulsed dendritic cells reduce anti-factor VIII antibody formation in the hemophilia A mouse model.
Volume: 37
Issue: 6
Pages: 744-54
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Publication
37116753 | J:340101
First Author: Cooke EJ
Year: 2023
Journal: J Thromb Haemost
Title: Maladaptive lymphangiogenesis is associated with synovial iron accumulation and delayed clearance in factor VIII-deficient mice after induced hemarthrosis.
Volume: 21
Issue: 9
Pages: 2390-2404
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Publication
18815284 | J:144256
First Author: Waters B
Year: 2009
Journal: Blood
Title: Anti-CD3 prevents factor VIII inhibitor development in hemophilia A mice by a regulatory CD4+CD25+-dependent mechanism and by shifting cytokine production to favor a Th1 response.
Volume: 113
Issue: 1
Pages: 193-203
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Publication
23231432 | J:195442
First Author: Sen D
Year: 2013
Journal: J Thromb Haemost
Title: Nuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia.
Volume: 11
Issue: 2
Pages: 293-306
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Publication
23372167 | J:197469
First Author: Siner JI
Year: 2013
Journal: Blood
Title: Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype.
Volume: 121
Issue: 21
Pages: 4396-403
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Publication
22655063 | J:187309
First Author: Sack BK
Year: 2012
Journal: PLoS One
Title: Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy.
Volume: 7
Issue: 5
Pages: e37671
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Publication
30064978 | J:265977
First Author: Muczynski V
Year: 2018
Journal: Blood
Title: A factor VIII-nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation.
Volume: 132
Issue: 11
Pages: 1193-1197
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Publication
10666206 | J:110275
First Author: Qian J
Year: 2000
Journal: Blood
Title: Prevention and treatment of factor VIII inhibitors in murine hemophilia A.
Volume: 95
Issue: 4
Pages: 1324-9
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Publication
28837614 | J:248312
First Author: Kiouptsi K
Year: 2017
Journal: PLoS One
Title: Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.
Volume: 12
Issue: 8
Pages: e0183590
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Publication
19139414 | J:143861
First Author: Xu D
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Phenotypic correction of murine hemophilia A using an iPS cell-based therapy.
Volume: 106
Issue: 3
Pages: 808-13
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Publication
25849132 | J:228247
First Author: Sehgal A
Year: 2015
Journal: Nat Med
Title: An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
Volume: 21
Issue: 5
Pages: 492-7
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Publication
32369559 | J:304769
First Author: Ferrière S
Year: 2020
Journal: Blood
Title: A hemophilia A mouse model for the in vivo assessment of emicizumab function.
Volume: 136
Issue: 6
Pages: 740-748
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22031860 | J:181577
First Author: Milanov P
Year: 2012
Journal: Blood
Title: Engineered factor IX variants bypass FVIII and correct hemophilia A phenotype in mice.
Volume: 119
Issue: 2
Pages: 602-11
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Publication
15728582 | J:99097
First Author: Purohit VS
Year: 2005
Journal: J Biol Chem
Title: Lower inhibitor development in hemophilia A mice following administration of recombinant factor VIII-O-phospho-L-serine complex.
Volume: 280
Issue: 18
Pages: 17593-600
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Publication
29656466 | J:271959
First Author: Mishra A
Year: 2018
Journal: Int J Exp Pathol
Title: Evaluation of high-fat high-fructose diet treatment in factor VIII (coagulation factor)-deficient mouse model.
Volume: 99
Issue: 1
Pages: 46-53
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11313267 | J:70448
First Author: Rossi G
Year: 2001
Journal: Blood
Title: Long-term induction of immune tolerance after blockade of CD40-CD40L interaction in a mouse model of hemophilia A.
Volume: 97
Issue: 9
Pages: 2750-7
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Publication
30021767 | J:264325
First Author: Zhang AH
Year: 2018
Journal: J Immunol
Title: Targeting Antigen-Specific B Cells Using Antigen-Expressing Transduced Regulatory T Cells.
Volume: 201
Issue: 5
Pages: 1434-1441
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Publication
15576475 | J:105059
First Author: Ohlfest JR
Year: 2005
Journal: Blood
Title: Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system.
Volume: 105
Issue: 7
Pages: 2691-8
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Publication
9576953 | J:47661
First Author: Evans GL
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Genetic induction of immune tolerance to human clotting factor VIII in a mouse model for hemophilia A.
Volume: 95
Issue: 10
Pages: 5734-9
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8896409 | J:36698
First Author: Bi L
Year: 1996
Journal: Blood
Title: Further characterization of factor VIII-deficient mice created by gene targeting: RNA and protein studies.
Volume: 88
Issue: 9
Pages: 3446-50
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25126862 | J:221006
First Author: Matsui H
Year: 2014
Journal: PLoS One
Title: Delivery of full-length factor VIII using a piggyBac transposon vector to correct a mouse model of hemophilia A.
Volume: 9
Issue: 8
Pages: e104957
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Publication
26775174 | J:234667
 
First Author: Krishnamoorthy S
Year: 2016
Journal: Cell Immunol
Title: Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice.
Volume: 301
Pages: 30-9
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Publication
27144769 | J:252467
First Author: Staber JM
Year: 2016
Journal: PLoS One
Title: Shortened Lifespan and Lethal Hemorrhage in a Hemophilia A Mouse Model.
Volume: 11
Issue: 5
Pages: e0154857
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26687613 | J:234671
 
First Author: Zhang AH
Year: 2016
Journal: Cell Immunol
Title: Tolerogenic nanoparticles to induce immunologic tolerance: Prevention and reversal of FVIII inhibitor formation.
Volume: 301
Pages: 74-81
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23426947 | J:196695
First Author: McIntosh J
Year: 2013
Journal: Blood
Title: Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.
Volume: 121
Issue: 17
Pages: 3335-44
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18559671 | J:139175
First Author: Neyman M
Year: 2008
Journal: Blood
Title: Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots.
Volume: 112
Issue: 4
Pages: 1101-8
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29395036 | J:306010
 
First Author: Peyron I
Year: 2018
Journal: Cell Immunol
Title: Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A.
Volume: 325
Pages: 64-68
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26825708 | J:232631
First Author: Eubanks J
Year: 2016
Journal: Blood
Title: A subset of high-titer anti-factor VIII A2 domain antibodies is responsive to treatment with factor VIII.
Volume: 127
Issue: 16
Pages: 2028-34
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19458355 | J:150739
First Author: Matsui H
Year: 2009
Journal: Blood
Title: A murine model for induction of long-term immunologic tolerance to factor VIII does not require persistent detectable levels of plasma factor VIII and involves contributions from Foxp3+ T regulatory cells.
Volume: 114
Issue: 3
Pages: 677-85
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25331117 | J:220788
First Author: Leong L
Year: 2015
Journal: Blood
Title: Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models.
Volume: 125
Issue: 2
Pages: 392-8
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Publication
14717974 | J:340394
First Author: Brown BD
Year: 2004
Journal: J Thromb Haemost
Title: Factors influencing therapeutic efficacy and the host immune response to helper-dependent adenoviral gene therapy in hemophilia A mice.
Volume: 2
Issue: 1
Pages: 111-8
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Publication
24358271 | J:209857
First Author: Tatsumi K
Year: 2013
Journal: PLoS One
Title: A novel cell-sheet technology that achieves durable factor VIII delivery in a mouse model of hemophilia A.
Volume: 8
Issue: 12
Pages: e83280
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Publication
29109275 | J:254329
First Author: Nielsen AL
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Engineering of a membrane-triggered activity switch in coagulation factor VIIa.
Volume: 114
Issue: 47
Pages: 12454-12459
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Publication
25534204 | J:230274
First Author: Bhatt S
Year: 2015
Journal: Exp Hematol
Title: Hepatic stellate cell-conditioned myeloid cells provide a novel therapy for prevention of factor VIII antibody formation in mice.
Volume: 43
Issue: 4
Pages: 277-85
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Publication
35143636 | J:326166
First Author: Magisetty J
Year: 2022
Journal: Blood
Title: Selective inhibition of activated protein C anticoagulant activity protects against hemophilic arthropathy in mice.
Volume: 139
Issue: 18
Pages: 2830-2841
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10779424 | J:61846
First Author: Fakharzadeh SS
Year: 2000
Journal: Blood
Title: Correction of the coagulation defect in hemophilia A mice through factor VIII expression in skin.
Volume: 95
Issue: 9
Pages: 2799-805
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24825864 | J:214325
First Author: Sherman A
Year: 2014
Journal: Blood
Title: Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells.
Volume: 124
Issue: 10
Pages: 1659-68
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Publication
35595575 | J:332201
 
First Author: Mashausi DS
Year: 2022
Journal: Biochem Biophys Res Commun
Title: A high efficient FVIII variant corrects bleeding in hemophilia A mouse model.
Volume: 637
Pages: 358-364
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16493498 | J:178969
First Author: Bril WS
Year: 2006
Journal: Thromb Haemost
Title: Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution.
Volume: 95
Issue: 2
Pages: 341-7
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20889922 | J:170788
First Author: Allacher P
Year: 2011
Journal: Blood
Title: Stimulation and inhibition of FVIII-specific memory B-cell responses by CpG-B (ODN 1826), a ligand for Toll-like receptor 9.
Volume: 117
Issue: 1
Pages: 259-67
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21788339 | J:177079
First Author: Pordes AG
Year: 2011
Journal: Blood
Title: T cell-independent restimulation of FVIII-specific murine memory B cells is facilitated by dendritic cells together with toll-like receptor 7 agonist.
Volume: 118
Issue: 11
Pages: 3154-62
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22394599 | J:183893
First Author: Steinitz KN
Year: 2012
Journal: Blood
Title: CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice.
Volume: 119
Issue: 17
Pages: 4073-82
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18495954 | J:140154
First Author: Shi Q
Year: 2008
Journal: Blood
Title: Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity.
Volume: 112
Issue: 7
Pages: 2713-21
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10557319 | J:58518
First Author: Lipshutz GS
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Short-term correction of factor VIII deficiency in a murine model of hemophilia A after delivery of adenovirus murine factor VIII in utero.
Volume: 96
Issue: 23
Pages: 13324-9
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27034428 | J:234697
First Author: Lai JD
Year: 2016
Journal: Blood
Title: Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A.
Volume: 127
Issue: 26
Pages: 3439-49
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21041718 | J:168395
First Author: Ward NJ
Year: 2011
Journal: Blood
Title: Codon optimization of human factor VIII cDNAs leads to high-level expression.
Volume: 117
Issue: 3
Pages: 798-807
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26668132 | J:232594
First Author: Chen Y
Year: 2016
Journal: Blood
Title: The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity.
Volume: 127
Issue: 10
Pages: 1346-54
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Publication
22498747 | J:185146
First Author: Wroblewska A
Year: 2012
Journal: Blood
Title: Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.
Volume: 119
Issue: 22
Pages: 5294-300
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9116285 | J:39215
First Author: Pemberton S
Year: 1997
Journal: Blood
Title: A molecular model for the triplicated A domains of human factor VIII based on the crystal structure of human ceruloplasmin.
Volume: 89
Issue: 7
Pages: 2413-21
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15920033 | J:114320
First Author: Khallou-Laschet J
Year: 2005
Journal: Arterioscler Thromb Vasc Biol
Title: Role of the intrinsic coagulation pathway in atherogenesis assessed in hemophilic apolipoprotein E knockout mice.
Volume: 25
Issue: 8
Pages: e123-6
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27758819 | J:306351
First Author: Gangadharan B
Year: 2017
Journal: Haematologica
Title: The C1 and C2 domains of blood coagulation factor VIII mediate its endocytosis by dendritic cells.
Volume: 102
Issue: 2
Pages: 271-281
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23178924 | J:306433
First Author: Golder M
Year: 2013
Journal: Thromb Haemost
Title: In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.
Volume: 109
Issue: 1
Pages: 53-60
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32453842 | J:309822
First Author: Shi Q
Year: 2020
Journal: Blood Adv
Title: Unexpected enhancement of FVIII immunogenicity by endothelial expression in lentivirus-transduced and transgenic mice.
Volume: 4
Issue: 10
Pages: 2272-2285
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Publication
- | J:14280
 
First Author: Grant S
Year: 1988
Journal: Mouse News Lett
Title: Mapping of mdx and Dmd.
Volume: 80
Pages: 181
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Publication
23722906 | J:201430
First Author: Macauley MS
Year: 2013
Journal: J Clin Invest
Title: Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis.
Volume: 123
Issue: 7
Pages: 3074-83
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22246033 | J:182551
First Author: Dumont JA
Year: 2012
Journal: Blood
Title: Prolonged activity of a recombinant factor VIII-Fc fusion protein in hemophilia A mice and dogs.
Volume: 119
Issue: 13
Pages: 3024-30
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Publication
26297739 | J:230678
First Author: Sharma R
Year: 2015
Journal: Blood
Title: In vivo genome editing of the albumin locus as a platform for protein replacement therapy.
Volume: 126
Issue: 15
Pages: 1777-84
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Publication
19126686 | J:143868
First Author: Ai D
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy.
Volume: 106
Issue: 2
Pages: 564-9
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Publication
22355108 | J:182144
First Author: Maroney SA
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Absence of hematopoietic tissue factor pathway inhibitor mitigates bleeding in mice with hemophilia.
Volume: 109
Issue: 10
Pages: 3927-31
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26426076 | J:315859
First Author: Matino D
Year: 2015
Journal: J Clin Invest
Title: IDO1 suppresses inhibitor development in hemophilia A treated with factor VIII.
Volume: 125
Issue: 10
Pages: 3766-81
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Publication
16762342 | J:111334
First Author: Sabherwal Y
Year: 2006
Journal: Exp Cell Res
Title: Integrin alpha2beta1 mediates the anti-angiogenic and anti-tumor activities of angiocidin, a novel tumor-associated protein.
Volume: 312
Issue: 13
Pages: 2443-53
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Publication
32294155 | J:301284
First Author: Magisetty J
Year: 2020
Journal: Blood
Title: EPCR deficiency or function-blocking antibody protects against joint bleeding-induced pathology in hemophilia mice.
Volume: 135
Issue: 25
Pages: 2211-2223
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Publication
24705491 | J:212401
First Author: Fahs SA
Year: 2014
Journal: Blood
Title: A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII.
Volume: 123
Issue: 24
Pages: 3706-13
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Publication
31465300 | J:286900
 
First Author: Wyseure T
Year: 2019
Journal: JCI Insight
Title: TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding.
Volume: 4
Issue: 19
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Publication
30026184 | J:270237
First Author: Wyseure T
Year: 2018
Journal: Blood
Title: Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding.
Volume: 132
Issue: 15
Pages: 1593-1603
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Publication
25833958 | J:222635
First Author: Biswas M
Year: 2015
Journal: Blood
Title: Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg.
Volume: 125
Issue: 19
Pages: 2937-47
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Publication
20194895 | J:162833
First Author: Mei B
Year: 2010
Journal: Blood
Title: Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment.
Volume: 116
Issue: 2
Pages: 270-9
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Publication
35508619 | J:325453
First Author: Milani M
Year: 2022
Journal: Nat Commun
Title: Liver-directed lentiviral gene therapy corrects hemophilia A mice and achieves normal-range factor VIII activity in non-human primates.
Volume: 13
Issue: 1
Pages: 2454
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Publication
36107620 | J:334220
 
First Author: Becker-Gotot J
Year: 2022
Journal: J Clin Invest
Title: Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs.
Volume: 132
Issue: 22
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Publication
15172967 | J:93755
First Author: Hakobyan N
Year: 2004
Journal: Blood
Title: Pathobiology of hemophilic synovitis I: overexpression of mdm2 oncogene.
Volume: 104
Issue: 7
Pages: 2060-4
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Publication
19713458 | J:154194
First Author: Miao CH
Year: 2009
Journal: Blood
Title: CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice.
Volume: 114
Issue: 19
Pages: 4034-44
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Publication
37720212 | J:340795
 
First Author: Batsuli G
Year: 2023
Journal: Front Immunol
Title: Factor VIII antibody immune complexes modulate the humoral response to factor VIII in an epitope-dependent manner.
Volume: 14
Pages: 1233356
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Publication
19890094 | J:160804
First Author: Dimitrov JD
Year: 2010
Journal: Blood
Title: Induction of heme oxygenase-1 in factor VIII-deficient mice reduces the immune response to therapeutic factor VIII.
Volume: 115
Issue: 13
Pages: 2682-5
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Publication
29429943 | J:260400
First Author: Wakabayashi T
Year: 2018
Journal: Cell Stem Cell
Title: CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.
Volume: 22
Issue: 3
Pages: 384-397.e6
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Publication
23335368 | J:195866
First Author: Stennicke HR
Year: 2013
Journal: Blood
Title: A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.
Volume: 121
Issue: 11
Pages: 2108-16
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Publication
22855607 | J:191310
First Author: Meeks SL
Year: 2012
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