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Search results 301 to 343 out of 343 for Klc1

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0.022s
Type Details Score
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Allele
Name: transgene insertion 73, Lawrence SB Goldstein
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 90, Lawrence SB Goldstein
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Transgene
Type: transgene
Organism: mouse, laboratory
Transgene
Type: transgene
Organism: mouse, laboratory
Strain
Attribute String: transgenic, congenic
Publication      
First Author: Goldstein LSB
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a low-expression kinesin light chain 1 transgene
Strain
Attribute String: transgenic, congenic
Publication      
First Author: Goldstein LSB
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a high-expression kinesin light chain 1 transgene
Allele
Name: kinesin light chain 1; targeted mutation 1, Lawrence S B Goldstein
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: congenic, mutant strain, targeted mutation
Genotype
Symbol: Klc1/Klc1
Background: either: (involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Klc1/Klc1
Background: B6.129-Klc1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Klc1/Klc1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Protein Domain
Type: Domain
Description: This entry represents the cytoplasmic C-terminal domain of calsyntenin (CLSTN) proteins 1, 2 and 3 (also known as alcadein-alpha, beta and gamma). These are postsynaptic Ca2-binding proteins, evolutionarily conserved type I membrane proteins. CLSTN (also known as Alc) forms a tripartite complex with APP (amyloid beta-protein precursor) and X11L (a neuron-specific adaptor protein) in brain; this complex stabilizes both APP and CLSTN proteins metabolically. Deficiencies in the X11L-mediated interaction between CLSTN and APP and/or CTFbeta enhances the production of amyloid beta-protein and have been linked to the development or progression of Alzheimer's disease []. Moreover, CLSTN1 strongly associates with kinesin-1 light chains (KLC1) and acts as a cargo that regulates kinesin-1 function. It may affect the transport of APP-containing vesicles by kinesin-1 []. This domain includes the WD motifs required for KLC1 interaction (although one WD motif is sufficient), and the NP motif [].
Publication
First Author: Araki Y
Year: 2003
Journal: J Biol Chem
Title: Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism.
Volume: 278
Issue: 49
Pages: 49448-58
Protein
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: false
Publication
First Author: Aoyama T
Year: 2009
Journal: J Cell Sci
Title: Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains.
Volume: 122
Issue: Pt 22
Pages: 4177-85
Publication
First Author: Morihara T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier.
Volume: 111
Issue: 7
Pages: 2638-43
Genotype
Symbol: Klc1/Klc1<+> Tg(APP695)3Dbo/?
Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 956  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 966  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 979  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 919  
Fragment?: false