| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:3507060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:2760523 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:5540017 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:6502 |
|
| Specimen Label: |
GUDMAP:6502 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
| Image: |
8b |
|
| Specimen Label: |
8b |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280928 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 56 |
|
|
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3280922 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1833322 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287022 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752522 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
| Image: |
EH1882; Specimen C2744 |
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3279028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
| Image: |
8b |
|
| Specimen Label: |
8b |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3279028 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 56 |
|
|
| Specimen Label: |
Not shown |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1821522 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3557722 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1702122 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3507060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:2852723 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:5540017 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:6502 |
|
| Specimen Label: |
GUDMAP:6502 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3507060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2874723 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:5540017 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:6502 |
|
| Specimen Label: |
GUDMAP:6502 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1756322 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1668822 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757722 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3525628 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757522 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3507060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:2850023 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:5540017 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:6502 |
|
| Specimen Label: |
GUDMAP:6502 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1738322 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1802422 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
| Image: |
8b |
|
| Specimen Label: |
8b |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 56 |
|
|
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521728 |
| Pattern: |
Patchy |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
| Image: |
8d |
|
| Specimen Label: |
8d |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
| Image: |
8g |
|
| Specimen Label: |
8g |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3507060 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796223 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:5540017 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:6502 |
|
| Specimen Label: |
GUDMAP:6502 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1768022 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
| Image: |
EH1882; Specimen C2744 |
| Note: |
Expression was strong in the skull (base and vault). |
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5310169 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2012-06-12 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2672022 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:5423493 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Expression was not detected in whisker follicle. |
| Specimen Label: |
EH1882; Specimen C2744 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3714829 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-07-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3561128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3714854 |
| Age: |
postnatal day 21 |
|
|
| Specimen Label: |
Table 1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamazaki M |
| Year: |
2013 |
| Journal: |
Neurosci Lett |
| Title: |
Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons. |
| Volume: |
547 |
|
| Pages: |
59-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qin Y |
| Year: |
2020 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation. |
| Volume: |
40 |
| Issue: |
5 |
| Pages: |
1311-1324 |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Halstead JR |
| Year: |
2010 |
| Journal: |
J Cell Sci |
| Title: |
Rac controls PIP5K localisation and PtdIns(4,5)Pâ‚‚ synthesis, which modulates vinculin localisation and neurite dynamics. |
| Volume: |
123 |
| Issue: |
Pt 20 |
| Pages: |
3535-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Akiba Y |
| Year: |
2002 |
| Journal: |
Brain Res Gene Expr Patterns |
| Title: |
Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development. |
| Volume: |
1 |
| Issue: |
2 |
| Pages: |
123-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee HK |
| Year: |
2015 |
| Journal: |
Neuron |
| Title: |
Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS. |
| Volume: |
85 |
| Issue: |
6 |
| Pages: |
1227-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang X |
| Year: |
2023 |
| Journal: |
Nature |
| Title: |
Reprogramming tumour-associated macrophages to outcompete cancer cells. |
| Volume: |
619 |
| Issue: |
7970 |
| Pages: |
616-623 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takasuga S |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine. |
| Volume: |
110 |
| Issue: |
5 |
| Pages: |
1726-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang Y |
| Year: |
2013 |
| Journal: |
Nat Immunol |
| Title: |
The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
858-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wiese CB |
| Year: |
2012 |
| Journal: |
Front Neurosci |
| Title: |
A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. |
| Volume: |
6 |
|
| Pages: |
130 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2016 |
|
| Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gray PA |
| Year: |
2004 |
| Journal: |
Science |
| Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
| Volume: |
306 |
| Issue: |
5705 |
| Pages: |
2255-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Visel A |
| Year: |
2004 |
| Journal: |
Nucleic Acids Res |
| Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
| Volume: |
32 |
| Issue: |
Database issue |
| Pages: |
D552-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
International Mouse Strain Resource |
| Year: |
2014 |
| Journal: |
Database Download |
| Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GUDMAP Consortium |
| Year: |
2004 |
| Journal: |
www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sbrissa D |
| Year: |
2004 |
| Journal: |
Mol Cell Biol |
| Title: |
A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity. |
| Volume: |
24 |
| Issue: |
23 |
| Pages: |
10437-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Compton LM |
| Year: |
2016 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency. |
| Volume: |
311 |
| Issue: |
3 |
| Pages: |
C366-77 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
156 |
| Description: |
In ingls; loss of interaction with Pikfyve but not with Fig4. |
| Type: |
sequence variant |
| End: |
156 |
|
•
•
•
•
•
|
| Interaction Experiment |
| Description: |
Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hill EV |
| Year: |
2010 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Regulation of PIKfyve phosphorylation by insulin and osmotic stress. |
| Volume: |
397 |
| Issue: |
4 |
| Pages: |
650-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim J |
| Year: |
2007 |
| Journal: |
Cancer Res |
| Title: |
The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus. |
| Volume: |
67 |
| Issue: |
19 |
| Pages: |
9229-37 |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
497
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2052
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
PIKfyve catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate []. It is part of the PI(3,5)P2 regulatory complex that regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) []. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol phosphate kinase) domain. |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alghamdi TA |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function. |
| Volume: |
288 |
| Issue: |
13 |
| Pages: |
9363-72 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Vac14 is a component of the PI(3,5)P2 regulatory complex, which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) []. This complex is composed of Atg18, Fig4, Fab1, Vac14 and Vac7 in yeast. In mammals it consists of PIKfyve, FIG4 and VAC14. Fab1/PIKfyve (Fab1 in yeast and PIKfyve in mammals) is a kinase that converts PI(3)P into PI(3,5)P2 by phosphorylation at the 5-position; conversely Fig4 dephosphorylates PI(3,5)P2 back to PI(3)P. Vac14 is a scaffolding adaptor protein whose multimerisation is a prerequisite step for PI(3,5)P2 complex assembly and function []. |
|
•
•
•
•
•
|