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Search results 101 to 193 out of 193 for Vamp8

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Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691382
Age: postnatal adult
Image: JAX_1631894
Specimen Label: JAX_1631894
Detected: true
Specimen Num: 28
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691382
Age: postnatal adult
Image: JAX_1631875
Specimen Label: JAX_1631875
Detected: true
Specimen Num: 9
Publication    
First Author: Wong SH
Year: 1998
Journal: GenBank Submission
Title: Mus musculus endobrevin mRNA, complete cds
Pages: AF053724
Publication
First Author: Graham GJ
Year: 2009
Journal: Blood
Title: Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo.
Volume: 114
Issue: 5
Pages: 1083-90
Publication
First Author: Wang CC
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Mouse lymphomas caused by an intron-splicing donor site deletion of the FasL gene.
Volume: 349
Issue: 1
Pages: 50-8
Publication
First Author: Bui TD
Year: 1998
Journal: Genomics
Title: Endobrevin maps to chromosome 2 in human and chromosome 6 in mouse.
Volume: 54
Issue: 3
Pages: 579-80
Publication    
First Author: Xia Y
Year: 2019
Journal: Autophagy
Title: The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Pages: 1-16
Publication
First Author: Puri N
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms.
Volume: 105
Issue: 7
Pages: 2580-5
Publication
First Author: Ren Q
Year: 2007
Journal: Mol Biol Cell
Title: Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction.
Volume: 18
Issue: 1
Pages: 24-33
Publication
First Author: Bastow ER
Year: 2012
Journal: Biol Open
Title: Evidence for lysosomal exocytosis and release of aggrecan-degrading hydrolases from hypertrophic chondrocytes, in vitro and in vivo.
Volume: 1
Issue: 4
Pages: 318-28
Publication
First Author: Best D
Year: 2009
Journal: Dev Dyn
Title: Sdmg1 is a component of secretory granules in mouse secretory exocrine tissues.
Volume: 238
Issue: 1
Pages: 223-31
Publication
First Author: Feng W
Year: 2011
Journal: Blood
Title: A novel role for platelet secretion in angiogenesis: mediating bone marrow-derived cell mobilization and homing.
Volume: 117
Issue: 14
Pages: 3893-902
Publication
First Author: Wankel B
Year: 2016
Journal: Mol Biol Cell
Title: Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells.
Volume: 27
Issue: 10
Pages: 1621-34
Publication
First Author: Peters CG
Year: 2012
Journal: Blood
Title: Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7.
Volume: 120
Issue: 1
Pages: 199-206
Publication
First Author: Williams D
Year: 2008
Journal: J Cell Biol
Title: Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes.
Volume: 180
Issue: 2
Pages: 375-87
Publication
First Author: Hasan N
Year: 2010
Journal: PLoS One
Title: Fusogenic pairings of vesicle-associated membrane proteins (VAMPs) and plasma membrane t-SNAREs--VAMP5 as the exception.
Volume: 5
Issue: 12
Pages: e14238
Publication
First Author: Advani RJ
Year: 1998
Journal: J Biol Chem
Title: Seven novel mammalian SNARE proteins localize to distinct membrane compartments.
Volume: 273
Issue: 17
Pages: 10317-24
Publication
First Author: Ouseph MM
Year: 2015
Journal: Blood
Title: Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis.
Volume: 126
Issue: 10
Pages: 1224-33
Publication
First Author: Gerst JE
Year: 1999
Journal: Cell Mol Life Sci
Title: SNAREs and SNARE regulators in membrane fusion and exocytosis.
Volume: 55
Issue: 5
Pages: 707-34
Publication
First Author: Best D
Year: 2008
Journal: Development
Title: Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice.
Volume: 135
Issue: 8
Pages: 1415-25
Publication
First Author: Richardson SC
Year: 2004
Journal: Mol Biol Cell
Title: Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.
Volume: 15
Issue: 3
Pages: 1197-210
Publication
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
Publication
First Author: Zambrowicz BP
Year: 1998
Journal: Nature
Title: Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.
Volume: 392
Issue: 6676
Pages: 608-11
Publication
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
Publication
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Pryor PR
Year: 2004
Journal: EMBO Rep
Title: Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events.
Volume: 5
Issue: 6
Pages: 590-5
Publication
First Author: Jean S
Year: 2015
Journal: EMBO Rep
Title: Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion.
Volume: 16
Issue: 3
Pages: 297-311
Publication
First Author: Liu Y
Year: 2011
Journal: J Physiol
Title: The role of synaptobrevin1/VAMP1 in Ca2+-triggered neurotransmitter release at the mouse neuromuscular junction.
Volume: 589
Issue: Pt 7
Pages: 1603-18
Publication
First Author: Söllner T
Year: 1993
Journal: Cell
Title: A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion.
Volume: 75
Issue: 3
Pages: 409-18
Protein Domain
Type: Family
Description: This entry includes vesicle-associated membrane proteins VAMP1/synaptobrevin-1, VAMP2/synaptobrevin-2, VAMP3/synaptobrevin-3 and VAMP8/endobrevin.VAMPs are a group of small, integral membrane proteins of synaptic vesicles that is mostly involved in vesicle fusion. The heterotrimeric SNARE complex isformed by syntaxin 1, synaptosomal-associated protein 25kDa (SNAP25), and vesicle-associated membrane protein (VAMP)/synaptobrevin []. VAMP1 plays an essential, non-redundant role in Ca2+-triggered vesicle exocytosis at the mouse neuromuscular junction []. VAMP2 is extensively expressed in the central nervous system []. Neurotransmitter release involves the assembly of a heterotrimeric SNARE complex composed of SNAP25, VAMP2 and syntaxin 1 []. VAMP8 may be involved in regulated exocytosis of the exocrine system [, ].
Publication
First Author: Bustos V
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.
Volume: 114
Issue: 27
Pages: 7148-7153
Publication
First Author: Dressel R
Year: 2010
Journal: J Immunol
Title: The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation.
Volume: 185
Issue: 2
Pages: 1005-14
Publication
First Author: Diaz-Vera J
Year: 2017
Journal: J Cell Sci
Title: A proteomic approach to identify endosomal cargoes controlling cancer invasiveness.
Volume: 130
Issue: 4
Pages: 697-711
Publication
First Author: Yang H
Year: 2019
Journal: Autophagy
Title: SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance.
Volume: 15
Issue: 9
Pages: 1539-1557
Publication
First Author: Achuthan A
Year: 2008
Journal: Mol Cell Biol
Title: Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.
Volume: 28
Issue: 20
Pages: 6149-59
Publication
First Author: Quetglas S
Year: 2002
Journal: EMBO J
Title: Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis.
Volume: 21
Issue: 15
Pages: 3970-9
Publication
First Author: Prekeris R
Year: 1999
Journal: Mol Biol Cell
Title: Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking.
Volume: 10
Issue: 11
Pages: 3891-908
Publication  
First Author: Subramaniam VN
Year: 2000
Journal: J Cell Sci
Title: Preferential association of syntaxin 8 with the early endosome.
Volume: 113 ( Pt 6)
Pages: 997-1008
Protein Domain
Type: Domain
Description: Syntaxin 8 forms a complex with syntaxin 7 (Qa), Vti1b (Qb) and either VAMP7 or VAMP8 (R-SNARE) and is involved in the transport from early endosomes to the lysosome [, ]. Syntaxin 8 is a member of the Qc subgroup of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins, which consist of coiled-coil helices (called SNARE motifs) that mediate the interactions between SNARE proteins, and a transmembrane domain []. The SNARE complexes mediate membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation []. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic centre layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qa-, as well as Qb- and Qc-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle [].
Publication
First Author: Antonin W
Year: 2002
Journal: Nat Struct Biol
Title: Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs.
Volume: 9
Issue: 2
Pages: 107-11
Publication
First Author: Teng FY
Year: 2001
Journal: Genome Biol
Title: The syntaxins.
Volume: 2
Issue: 11
Pages: REVIEWS3012
Protein
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 118  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 102  
Fragment?: false
Publication
First Author: Fasshauer D
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs.
Volume: 95
Issue: 26
Pages: 15781-6