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Search results 1 to 100 out of 540 for Hnf1a

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0.038s
Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Kalisz M
Year: 2020
Journal: EMBO J
Title: HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Volume: 39
Issue: 9
Pages: e102808
Publication  
First Author: Song H
Year: 2023
Journal: JCI Insight
Title: High-fat diet plus HNF1A variant promotes polyps by activating β-catenin in early-onset colorectal cancer.
Volume: 8
Issue: 13
Publication
First Author: Beucher A
Year: 2022
Journal: Nat Cell Biol
Title: The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A.
Volume: 24
Issue: 10
Pages: 1528-1540
Publication
First Author: Shih DQ
Year: 2001
Journal: Diabetes
Title: Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism.
Volume: 50
Issue: 11
Pages: 2472-80
Publication
First Author: Servitja JM
Year: 2009
Journal: Mol Cell Biol
Title: Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.
Volume: 29
Issue: 11
Pages: 2945-59
Publication
First Author: Bonzo JA
Year: 2010
Journal: Mol Endocrinol
Title: Metabolomics identifies novel Hnf1alpha-dependent physiological pathways in vivo.
Volume: 24
Issue: 12
Pages: 2343-55
Publication
First Author: von Wnuck Lipinski K
Year: 2017
Journal: Blood
Title: Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasis.
Volume: 130
Issue: 25
Pages: 2786-2798
Publication
First Author: Brial F
Year: 2015
Journal: Diabetes
Title: Ghrelin Inhibition Restores Glucose Homeostasis in Hepatocyte Nuclear Factor-1α (MODY3)-Deficient Mice.
Volume: 64
Issue: 9
Pages: 3314-20
Publication
First Author: D'Angelo A
Year: 2010
Journal: Development
Title: Hepatocyte nuclear factor 1alpha and beta control terminal differentiation and cell fate commitment in the gut epithelium.
Volume: 137
Issue: 9
Pages: 1573-82
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lee YH
Year: 1998
Journal: Mol Cell Biol
Title: Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse.
Volume: 18
Issue: 5
Pages: 3059-68
Publication
First Author: Rose RB
Year: 2000
Journal: Biochemistry
Title: High-resolution structure of the HNF-1alpha dimerization domain.
Volume: 39
Issue: 49
Pages: 15062-70
Publication
First Author: Fukui K
Year: 2005
Journal: Cell Metab
Title: The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation.
Volume: 2
Issue: 6
Pages: 373-84
Publication
First Author: Yamagata K
Year: 2002
Journal: Diabetes
Title: Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes.
Volume: 51
Issue: 1
Pages: 114-23
Publication
First Author: Chu Y
Year: 2023
Journal: Diabetes
Title: Lysine 117 Residue Is Essential for the Function of the Hepatocyte Nuclear Factor 1α.
Volume: 72
Issue: 10
Pages: 1502-1516
Publication
First Author: Lee YH
Year: 2003
Journal: Mol Cell Biol
Title: Liver-specific reactivation of the inactivated Hnf-1alpha gene: elimination of liver dysfunction to establish a mouse MODY3 model.
Volume: 23
Issue: 3
Pages: 923-32
Publication
First Author: Akiyama TE
Year: 2000
Journal: J Biol Chem
Title: Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1alpha (HNF1alpha). Alterations in fatty acid homeostasis in HNF1alpha-deficient mice.
Volume: 275
Issue: 35
Pages: 27117-22
Publication
First Author: Cheung C
Year: 2003
Journal: Biochem Pharmacol
Title: Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice.
Volume: 66
Issue: 10
Pages: 2011-20
Publication
First Author: Dukes ID
Year: 1998
Journal: J Biol Chem
Title: Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice.
Volume: 273
Issue: 38
Pages: 24457-64
Publication
First Author: Luco RF
Year: 2008
Journal: PLoS Genet
Title: Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targets.
Volume: 4
Issue: 5
Pages: e1000079
Publication  
First Author: Boileau P
Year: 2002
Journal: Diabetes
Title: Decreased glibenclamide uptake in hepatocytes of hepatocyte nuclear factor-1alpha-deficient mice: a mechanism for hypersensitivity to sulfonylurea therapy in patients with maturity-onset diabetes of the young, type 3 (MODY3).
Volume: 51 Suppl 3
Pages: S343-8
Publication
First Author: Bosse T
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo.
Volume: 290
Issue: 5
Pages: G1016-24
Publication
First Author: Luco RF
Year: 2006
Journal: Diabetes
Title: A conditional model reveals that induction of hepatocyte nuclear factor-1alpha in Hnf1alpha-null mutant beta-cells can activate silenced genes postnatally, whereas overexpression is deleterious.
Volume: 55
Issue: 8
Pages: 2202-11
Publication
First Author: Ni Q
Year: 2017
Journal: FEBS Lett
Title: Deletion of HNF1α in hepatocytes results in fatty liver-related hepatocellular carcinoma in mice.
Volume: 591
Issue: 13
Pages: 1947-1957
Publication
First Author: Pontoglio M
Year: 2001
Journal: J Exp Med
Title: Hepatocyte nuclear factor 1alpha controls the expression of terminal complement genes.
Volume: 194
Issue: 11
Pages: 1683-9
Publication
First Author: Anderson AL
Year: 2005
Journal: J Virol
Title: Alpha/beta interferon differentially modulates the clearance of cytoplasmic encapsidated replication intermediates and nuclear covalently closed circular hepatitis B virus (HBV) DNA from the livers of hepatocyte nuclear factor 1alpha-null HBV transgenic mice.
Volume: 79
Issue: 17
Pages: 11045-52
Publication
First Author: Pontoglio M
Year: 1998
Journal: J Clin Invest
Title: Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
Volume: 101
Issue: 10
Pages: 2215-22
Publication
First Author: Mostofa MG
Year: 2022
Journal: J Biol Chem
Title: MicroRNA-200c coordinates HNF1 homeobox B and apolipoprotein O functions to modulate lipid homeostasis in alcoholic fatty liver disease.
Volume: 298
Issue: 6
Pages: 101966
Publication
First Author: Malakauskas SM
Year: 2009
Journal: Mol Endocrinol
Title: Increased insulin sensitivity in mice lacking collectrin, a downstream target of HNF-1alpha.
Volume: 23
Issue: 6
Pages: 881-92
Publication
First Author: Miura N
Year: 1993
Journal: Eur J Cell Biol
Title: Immunological characterization of hepatocyte nuclear factor 1 protein: appearance of hepatocyte nuclear factor 1 protein in developing mouse embryos.
Volume: 60
Issue: 2
Pages: 376-82
Publication
First Author: Vandromme M
Year: 1996
Journal: Trends Biochem Sci
Title: Regulation of transcription factor localization: fine-tuning of gene expression.
Volume: 21
Issue: 2
Pages: 59-64
Publication
First Author: Yamagata K
Year: 1996
Journal: Nature
Title: Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Volume: 384
Issue: 6608
Pages: 455-8
Publication
First Author: Jakowlew SB
Year: 1998
Journal: Mol Carcinog
Title: Reduction in transforming growth factor-beta type II receptor in mouse lung carcinogenesis.
Volume: 22
Issue: 1
Pages: 46-56
Publication  
First Author: Winzell MS
Year: 2004
Journal: Diabetes
Title: Beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1alpha in mice: diabetes model with beta-cell dysfunction partially rescued by nonglucose secretagogues.
Volume: 53 Suppl 3
Pages: S92-6
Publication
First Author: Watanabe T
Year: 2020
Journal: Sci Rep
Title: Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Factor-1 in the Murine Liver.
Volume: 10
Issue: 1
Pages: 9999
GXD Expression    
Probe: MGI:1335858
Assay Type: RT-PCR
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1337763
Age: embryonic day 8.5
Image: 5
Specimen Label: +RT wt
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1335858
Assay Type: RT-PCR
Annotation Date: 1999-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604013
Stage: TS13
Assay Id: MGI:1337763
Age: embryonic day 8.5
Image: 5
Specimen Label: +RT -/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:2662318
Assay Type: Northern blot
Annotation Date: 2003-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:2662331
Age: embryonic day 14.0
Specimen Label: E14
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:2662318
Assay Type: Northern blot
Annotation Date: 2003-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:2662331
Age: postnatal day 0
Specimen Label: Neonatal
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2662318
Assay Type: Northern blot
Annotation Date: 2003-06-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2662331
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3513003
Age: postnatal newborn
Specimen Label: neonatal WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3513003
Age: postnatal newborn
Specimen Label: neonatal KO
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 2
Specimen Label: 2 month WT
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 2
Specimen Label: 2 month KO
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 6
Specimen Label: 6 month WT
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 6
Specimen Label: 6 month KO
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3513003
Age: postnatal newborn
Specimen Label: neonatal WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:3513003
Age: postnatal newborn
Specimen Label: neonatal KO
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 2
Specimen Label: 2 month WT
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 2
Specimen Label: 2 month KO
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 6
Specimen Label: 6 month WT
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513003
Age: postnatal month 6
Specimen Label: 6 month KO
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513009
Age: postnatal day 45
Specimen Label: 45 days WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3512875
Assay Type: Northern blot
Annotation Date: 2005-01-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513009
Age: postnatal day 45
Specimen Label: 45 days WT
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3513173
Assay Type: RT-PCR
Annotation Date: 2005-01-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:3513202
Age: embryonic day 7.5
Specimen Label: E d7.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3513173
Assay Type: RT-PCR
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1631915
Stage: TS15
Assay Id: MGI:3513202
Age: embryonic day 9.5
Specimen Label: E d9.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3513173
Assay Type: RT-PCR
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:3513202
Age: embryonic day 11.5
Specimen Label: E d11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3513173
Assay Type: RT-PCR
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:3513202
Age: embryonic day 13.5
Specimen Label: E d13.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3513173
Assay Type: RT-PCR
Annotation Date: 2005-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513202
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636317
Stage: TS17
Assay Id: MGI:3800272
Age: embryonic day 10.5
Image: 2
Specimen Label: 10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Stage: TS19
Assay Id: MGI:3800272
Age: embryonic day 11.5
Image: 2
Specimen Label: 11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Stage: TS20
Assay Id: MGI:3800272
Age: embryonic day 12.5
Image: 2
Specimen Label: 12.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Stage: TS21
Assay Id: MGI:3800272
Age: embryonic day 13.5
Image: 2
Specimen Label: 13.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3800272
Age: embryonic day 14.5
Image: 2
Specimen Label: 14.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3799860
Assay Type: RT-PCR
Annotation Date: 2008-08-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Stage: TS23
Assay Id: MGI:3800272
Age: embryonic day 15.5
Image: 2
Specimen Label: 15.5
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816600
Age: postnatal
Specimen Label: Metaphase II
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816600
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816600
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816600
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3815796
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816600
Age: embryonic day 3.0
Specimen Label: Morula
Detected: false
Specimen Num: 5