Peroxiredoxin-like 2A (PRXL2A), also known as peroxiredoxin-like 2 activated in M-CSF stimulated monocytes (PAMM) or redox-regulatory protein FAM213A, is a secreted redox regulatory protein with potent anti-inflammatory properties []. It has been identified as a redox regulatory protein that modulates osteoclast differentiation in vitro[].
This family consists of proteins from the peroxiredoxin-like family, including PRXL2A, PXL2B (also known as prostamide/prostaglandin F synthase) []and PXL2C (also known as AAED1). PRXL2A is a secreted redox regulatory protein with potent anti-inflammatory properties []. PXL2C regulates proliferation and glycolysis in gastric cancer [].
