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Search results 301 to 318 out of 318 for G3bp1

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Type

Details

Score

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

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Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

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Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

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Publication

32521269 | J:304685

First Author:	Lo LH
Year:	2020
Journal:	Cell Rep
Title:	The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation.
Volume:	31
Issue:	10
Pages:	107744

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Publication

20663914 | -

First Author:	Ortega AD
Year:	2010
Journal:	J Cell Sci
Title:	Human G3BP1 interacts with beta-F1-ATPase mRNA and inhibits its translation.
Volume:	123
Issue:	Pt 16
Pages:	2685-96

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Allele

G3bp1<em1Smoc> | MGI:7289781

Name:	G3BP stress granule assembly factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

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Publication

23279204 | -

First Author:	Matsuki H
Year:	2013
Journal:	Genes Cells
Title:	Both G3BP1 and G3BP2 contribute to stress granule formation.
Volume:	18
Issue:	2
Pages:	135-46

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Protein Domain

IPR034374 | G3BP1_RRM

Type:

Domain

Description:

This entry represents the RNA recognition motif (RRM) of G3BP1, which has been identified as a phosphorylation-dependent endoribonuclease that interacts with the SH3 domain of RasGAP []. However, this interaction has been questioned []. G3BP1 binds to and cleaves the 3'-untranslated region (3'-UTR) of the c-myc mRNA in a phosphorylation-dependent manner []. G3BP1 has been linked to the formation of stress granules (SGs), membrane-less structures consisting of mRNA and protein aggregates form rapidly in response to a wide range of stresses and viral infections [, ]. G3BP1 is targeted by many viruses and may be involved in innate immune response [, ]. Its activities can be regulated through post-translational modifications [].It has also been shown that G3BP1 is a novel Dishevelled-associated protein that is methylated upon Wnt3a stimulation and that arginine methylation of G3BP1 regulates both Ctnnb1 mRNA and canonical Wnt/beta-catenin signaling []. Furthermore, G3BP1 can be associated with the 3'-UTR of beta-F1 mRNA in cytoplasmic RNA-granules, demonstrating that G3BP1 may specifically repress the translation of the transcript [].G3BP1 contains an N-terminal nuclear transfer factor 2 (NTF2)-like domain, an RNA recognition motif (RRM domain), and an Arg-Gly-rich region (RGG-rich region, or arginine methylation motif). The RRM domain and RGG-rich region are canonically associated with RNA binding [].

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Allele

Del(11Nmur2-Sparc)2Anjm | MGI:4421680

Name:	deletion, Chr 11, Andrew N J McKenzie
Allele Type:	Targeted
Attribute String:	Null/knockout

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Genotype

Symbol:	Del(11Nmur2-Sparc)2Anjm/+ Del(11Sparc-Gpx3)91Anjm/+
Background:	involves: 129P2/OlaHsd * C57BL/6
Zygosity:	cx
Has Mutant Allele:	true

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Publication

32692974 | J:297181

First Author:	Lee AK
Year:	2020
Journal:	Mol Cell
Title:	Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance.
Volume:	79
Issue:	4
Pages:	645-659.e9

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Publication

34110282 | J:307481

First Author:	Dou S
Year:	2021
Journal:	Elife
Title:	Ubiquitination and degradation of NF90 by Tim-3 inhibits antiviral innate immunity.
Volume:	10

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Publication

37474791 | J:340113

First Author:	Li D
Year:	2023
Journal:	Nat Aging
Title:	LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits.
Volume:	3
Issue:	8
Pages:	1001-1019

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Publication

31462091 | J:313369

First Author:	Herman AB
Year:	2019
Journal:	Arterioscler Thromb Vasc Biol
Title:	Regulation of Stress Granule Formation by Inflammation, Vascular Injury, and Atherosclerosis.
Volume:	39
Issue:	10
Pages:	2014-2027

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Publication

32149416 | J:299785

First Author:	Pla-Martín D
Year:	2020
Journal:	EMBO J
Title:	CLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy.
Volume:	39
Issue:	9
Pages:	e102731

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Publication

19966810 | J:155870

First Author:	Barlow JL
Year:	2010
Journal:	Nat Med
Title:	A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.
Volume:	16
Issue:	1
Pages:	59-66

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