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Search results 101 to 193 out of 193 for Ptx3

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:5817436
Assay Type: RT-PCR
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524728
Stage: TS28
Assay Id: MGI:5817437
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5817478
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:5817479
Age: postnatal day 0
Specimen Label: P0 cochlea
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5817478
Assay Type: Western blot
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728627
Stage: TS27
Assay Id: MGI:5817479
Age: postnatal day 0
Specimen Label: P0 vestibule
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5817478
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5817482
Age: postnatal day 0
Note: Expression is in the cellular outline of hair and supporting cells.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5817478
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5817482
Age: postnatal day 0
Note: Expression is in the boundaries between hair and supporting cells, in hair cell stereocilia, and is strongest surrounding the supporting pillar cells.
Specimen Label: 3E
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6181654
Assay Type: RNA in situ
Annotation Date: 2023-11-28
Strength: Present
Sex: Male
Emaps: EMAPS:3583128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7561636
Age: postnatal day 56
Image: S3
Specimen Label: S3
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5817478
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5817482
Age: postnatal day 0
Note: Expression is in the sensory epithelium.
Specimen Label: 3C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5817478
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5817482
Age: postnatal day 0
Note: Expression is in the cellular outline of hair and supporting cells.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5817478
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3582727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5817482
Age: postnatal day 0
Specimen Label: 3C
Detected: true
Specimen Num: 1
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Publication
22019014 | J:177859
First Author: Kim J
Year: 2011
Journal: Cell Stem Cell
Title: Functional integration of dopaminergic neurons directly converted from mouse fibroblasts.
Volume: 9
Issue: 5
Pages: 413-9
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Publication
15894273 | J:99105
First Author: Jeannin P
Year: 2005
Journal: Immunity
Title: Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.
Volume: 22
Issue: 5
Pages: 551-60
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Publication
12000727 | J:133735
First Author: Souza DG
Year: 2002
Journal: Am J Pathol
Title: Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury.
Volume: 160
Issue: 5
Pages: 1755-65
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Publication
23217261 | J:195098
First Author: Tsukita S
Year: 2012
Journal: Cell Metab
Title: Hepatic glucokinase modulates obesity predisposition by regulating BAT thermogenesis via neural signals.
Volume: 16
Issue: 6
Pages: 825-32
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Publication
27301880 | J:325824
First Author: Zelante T
Year: 2017
Journal: Mucosal Immunol
Title: Impaired calcineurin signaling in myeloid cells results in downregulation of pentraxin-3 and increased susceptibility to aspergillosis.
Volume: 10
Issue: 2
Pages: 470-480
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Publication
22384161 | J:185299
First Author: Rong J
Year: 2012
Journal: PLoS One
Title: Identification of candidate susceptibility and resistance genes of mice infected with Streptococcus suis type 2.
Volume: 7
Issue: 2
Pages: e32150
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Publication
28360101 | J:242764
First Author: Matsuda M
Year: 2017
Journal: J Biol Chem
Title: Phospholipase C-related but catalytically inactive proteins regulate ovarian follicle development.
Volume: 292
Issue: 20
Pages: 8369-8380
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Publication
32041791 | J:291489
 
First Author: Chui A
Year: 2020
Journal: Development
Title: Oxidative stress regulates progenitor behavior and cortical neurogenesis.
Volume: 147
Issue: 5
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Publication
10585298 | J:58939
First Author: Wallén A
Year: 1999
Journal: Exp Cell Res
Title: Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice.
Volume: 253
Issue: 2
Pages: 737-46
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Publication
22280990 | J:182757
First Author: Wilson DG
Year: 2012
Journal: Dev Biol
Title: Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning.
Volume: 363
Issue: 2
Pages: 413-25
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Publication
29779941 | J:269647
First Author: Baizabal JM
Year: 2018
Journal: Neuron
Title: The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.
Volume: 98
Issue: 5
Pages: 945-962.e8
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Publication
35175194 | J:321499
   
First Author: Lee DR
Year: 2022
Journal: Elife
Title: Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.
Volume: 11
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
21308776 | J:233118
First Author: Abdallah BM
Year: 2011
Journal: J Bone Miner Res
Title: DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Volume: 26
Issue: 7
Pages: 1457-71
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
24154525 | J:205051
First Author: Miller JA
Year: 2013
Journal: Development
Title: Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Volume: 140
Issue: 22
Pages: 4633-44
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 18
Description: Pentraxin-related protein PTX3
Type: chain
End: 381
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Allele
Ptx3<tm1Zuk> | MGI:2670952
Name: pentraxin related gene; targeted mutation 1, Martin M Matzuk
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
9407058 | -
First Author: Bottazzi B
Year: 1997
Journal: J Biol Chem
Title: Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component.
Volume: 272
Issue: 52
Pages: 32817-23
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Publication
12763682 | -
 
First Author: Mantovani A
Year: 2003
Journal: Vaccine
Title: Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity.
Volume: 21 Suppl 2
Pages: S43-7
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Publication
32508664 | J:311441
 
First Author: Farini A
Year: 2020
Journal: Front Physiol
Title: PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy.
Volume: 11
Pages: 403
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Publication
36651911 | J:335824
First Author: Xu Z
Year: 2023
Journal: Cardiovasc Res
Title: PTX3 from vascular endothelial cells contributes to trastuzumab-induced cardiac complications.
Volume: 119
Issue: 5
Pages: 1250-1264
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Publication
9371841 | J:44602
First Author: Smidt MP
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons.
Volume: 94
Issue: 24
Pages: 13305-10
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Publication
21112127 | J:188222
First Author: Ko CY
Year: 2012
Journal: Neurobiol Aging
Title: CCAAT/enhancer binding protein delta (CEBPD) elevating PTX3 expression inhibits macrophage-mediated phagocytosis of dying neuron cells.
Volume: 33
Issue: 2
Pages: 422.e11-25
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Allele
Ptx3<em1Smoc> | MGI:7291914
Name: pentraxin related gene; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Coding Gene
MGI:1100498 | Pitx3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
B1AR39
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: false
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Publication
8530029 | -
First Author: Hsu YC
Year: 1995
Journal: Genomics
Title: Human neuronal pentraxin II (NPTX2): conservation, genomic structure, and chromosomal localization.
Volume: 28
Issue: 2
Pages: 220-7
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Publication
7695898 | -
First Author: Schlimgen AK
Year: 1995
Journal: Neuron
Title: Neuronal pentraxin, a secreted protein with homology to acute phase proteins of the immune system.
Volume: 14
Issue: 3
Pages: 519-26
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Protein Domain
IPR030476 | Pentaxin_CS
Type: Conserved_site
Description: Pentaxins (or pentraxins) [, ]are a family of proteins which show, underelectron microscopy, a discoid arrangement of five noncovalently boundsubunits. Proteins known to belong to this family are:C-reactive protein (CRP), a protein which, in mammals,is expressed duringacute phase response to tissue injury or inflammation. CRP displays severalfunctions associated with host defense: it promotes agglutination,bacterial capsular swelling, phagocytosis and complement fixation throughits calcium-dependent binding to phosphorylcholine. CRPs have also beensequenced in an invertebrate, the Atlantic horseshoe crab, where they are anormal constituent of the hemolymph.Serum Amyloid P-component (SAP), a precursor of amyloid component P whichis found in basement membrane and is associated with amyloid deposits.Hamster female protein (FP), a plasma protein whose concentration isaltered by sex steroids and stimuli that elicit an acute phase response.A number of proteins, whose function is not yet clear, contain a C-terminalpentaxin-like domain. These proteins are:Human PTX3 (or TSG-14). PTX3 is a cytokine-induced protein.Guinea pig apexin [], a sperm acrosomal protein. Apexin seems to be theortholog of human neuronal pentraxin II (gene NPTX2) [].Rat neuronal pentaxin I [].The sequences of the different members of this family are quite conserved. This entry represents a six residue pattern which includes a cysteineknown to be involved in a disulfide bridge in CRPs and SAP.
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Publication
10725922 | J:77664
First Author: Smidt MP
Year: 2000
Journal: Nat Neurosci
Title: A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b.
Volume: 3
Issue: 4
Pages: 337-41
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Publication
25670793 | J:238889
First Author: Wu LL
Year: 2015
Journal: Development
Title: Mitochondrial dysfunction in oocytes of obese mothers: transmission to offspring and reversal by pharmacological endoplasmic reticulum stress inhibitors.
Volume: 142
Issue: 4
Pages: 681-91
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Publication
16641236 | J:108403
First Author: Kim SY
Year: 2006
Journal: J Neurosci
Title: The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation.
Volume: 26
Issue: 17
Pages: 4567-76
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Publication
12498783 | J:80942
First Author: Asbreuk CH
Year: 2002
Journal: Mol Cell Neurosci
Title: CNS expression pattern of Lmx1b and coexpression with ptx genes suggest functional cooperativity in the development of forebrain motor control systems.
Volume: 21
Issue: 3
Pages: 410-20
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Publication
6356809 | -
 
First Author: Pepys MB
Year: 1983
Journal: Adv Immunol
Title: Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein.
Volume: 34
Pages: 141-212
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Publication
7772283 | J:24416
First Author: Gewurz H
Year: 1995
Journal: Curr Opin Immunol
Title: Structure and function of the pentraxins.
Volume: 7
Issue: 1
Pages: 54-64
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Publication
7798266 | -
First Author: Reid MS
Year: 1994
Journal: J Biol Chem
Title: Apexin, an acrosomal pentaxin.
Volume: 269
Issue: 51
Pages: 32615-20
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Protein
O70340
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Q99J85
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
P14847
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Protein
P12246
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: false
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Protein
Q62443
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: false
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Protein
Q3UH37
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Protein
Q6TLW2
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
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Protein
Q3UYB9
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
E9PZM8
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
Q6PD36
Organism: Mus musculus/domesticus
Length: 320  
Fragment?: false
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Protein
Q542I3
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Protein
Q3UST4
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: true
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Protein
Q3UH69
Organism: Mus musculus/domesticus
Length: 554  
Fragment?: true
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Protein
B9EIV5
Organism: Mus musculus/domesticus
Length: 490  
Fragment?: false
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Protein
I6L966
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: false
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Protein
A2ACL9
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: false
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Protein
Q4JFI8
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: false
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Protein
F8VQB8
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Protein
Q6TLW0
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Protein
Q6TKP2
Organism: Mus musculus/domesticus
Length: 672  
Fragment?: false
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Protein
H3BLN6
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Protein
Q6TLW1
Organism: Mus musculus/domesticus
Length: 372  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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