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Search results 101 to 157 out of 157 for Pex7

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Type Details Score
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Allele
Pex7<em2Lutzy> | MGI:6861860
Name: peroxisomal biogenesis factor 7; endonuclease-mediated mutation 2, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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GO Term
GO:0005053 | peroxisome matrix targeting signal-2 binding
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Allele
Pex7<tm1Nbra> | MGI:4443125
Name: peroxisomal biogenesis factor 7; targeted mutation 1, Nancy Braverman
Allele Type: Targeted
Attribute String: Hypomorph
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Allele
Pex7<tm1Rjaw> | MGI:3052739
Name: peroxisomal biogenesis factor 7; targeted mutation 1, Ronald JA Wanders
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Genotype
Genotype
Symbol: Pex7/Pex7
Background: Swiss
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pex7/Pex7
Background: involves: 129S/SvEv * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110851 | rhizomelic chondrodysplasia punctata type 1
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DO Term
DOID:0081438 | Peroxisome biogenesis disorder 9B
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Ontology Term
- | Rhizomelic chondrodysplasia punctata
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Publication
22550182 | J:184786
First Author: Bankston JR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
Volume: 109
Issue: 20
Pages: 7899-904
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Publication
32189562 | -
First Author: Han Y
Year: 2020
Journal: Channels (Austin)
Title: The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels.
Volume: 14
Issue: 1
Pages: 110-122
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Protein Domain
IPR024111 | PEX5/PEX5L
Type: Family
Description: Peroxisomal proteins catalyse metabolic reactions. The import of proteins from the cytosol into the peroxisomes matrix depends on more than a dozen peroxin (PEX) proteins, among which PEX5 and PEX7 serve as receptors that shuttle proteins bearing one of two peroxisome-targeting signals (PTSs) into the organelle. PEX5 is the PTS1 receptor, while PEX7 is the PTS2 receptor. In plants, PEX7 depends on PEX5 binding to deliver PTS2 cargo into the peroxisome, and PEX7 also facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes [, ]. This entry include PEX5 (also known as PTS1R) from animals, fungi and plants. This entry also includes PEX5L from vertebrates. PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import [, , ]. Based on subcellular localization and binding properties mammalian PEX5 may function as a regulator in an early step of the PTS1 protein import process []. PEX5L acts as an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence [, ]. Interestingly, although PEX5 and PEX5L have structurally similar binding at their TPR domains, they bind to different substrates in vivo [].
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Publication
11606046 | -
First Author: Ito R
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Temperature-sensitive phenotype of Chinese hamster ovary cells defective in PEX5 gene.
Volume: 288
Issue: 2
Pages: 321-7
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Publication
16428307 | -
First Author: Ito R
Year: 2005
Journal: J Biochem
Title: Identification of Pex5pM, and retarded maturation of 3-ketoacyl-CoA thiolase and acyl-CoA oxidase in CHO cells expressing mutant Pex5p isoforms.
Volume: 138
Issue: 6
Pages: 781-90
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Publication
11865044 | -
First Author: Otera H
Year: 2002
Journal: Mol Cell Biol
Title: Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import.
Volume: 22
Issue: 6
Pages: 1639-55
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Publication
11463335 | J:188908
First Author: Amery L
Year: 2001
Journal: Biochem J
Title: Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.
Volume: 357
Issue: Pt 3
Pages: 635-46
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Publication
17056133 | -
First Author: Williams C
Year: 2006
Journal: Biochim Biophys Acta
Title: Pex13p: docking or cargo handling protein?
Volume: 1763
Issue: 12
Pages: 1585-91
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Publication
12167700 | -
First Author: Stein K
Year: 2002
Journal: Mol Cell Biol
Title: Interactions of Pex7p and Pex18p/Pex21p with the peroxisomal docking machinery: implications for the first steps in PTS2 protein import.
Volume: 22
Issue: 17
Pages: 6056-69
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Protein Domain
IPR035463 | Pex13
Type: Family
Description: Peroxin-13 (Pex13), located in the peroxisomal membrane, is a component of the peroxisomal translocation machinery with peroxin-14 and peroxin-17. Both termini of peroxin-13 are oriented to the cytosol. It is required for peroxisomal association of peroxin-14 []. Both human and budding yeast Pex13 bind to the PTS1 signal recognition factor Pex5. However, they bind to Pex5 through different binding sites []. In budding yeasts, Pex13 is also involved in the PTS2 signal recognition through its interaction with Pex7 [].
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Publication
25162638 | -
First Author: El Magraoui F
Year: 2014
Journal: PLoS One
Title: The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.
Volume: 9
Issue: 8
Pages: e105894
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Publication
16272432 | -
First Author: Zolman BK
Year: 2005
Journal: Plant Cell
Title: Identification and functional characterization of Arabidopsis PEROXIN4 and the interacting protein PEROXIN22.
Volume: 17
Issue: 12
Pages: 3422-35
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Protein Domain
IPR037485 | PEX22
Type: Family
Description: Peroxisomal proteins, called peroxins, participate in the process of peroxisome assembly. Specific amino acid sequences (PTS or peroxisomal targeting signal) at the C terminus (PTS1) or N terminus (PTS2) are present in peroxisomal matrix proteins, which signals them to be imported. The protein receptors Pex5 and Pex7 accompany their cargoes (containing a PTS1 or a PTS2 amino acid sequence, respectively) into the peroxisome. Ubiquitination appears to be crucial for the export of Pex5 from the peroxisome to the cytosol. The monoubiquitination of the PTS1-receptor Pex5p is catalyzed by the E2 enzyme Pex4.Pex22 anchors Pex4 to the peroxisome membrane [, ]. Moreover, Pex4 requires the interaction with Pex22 to display full activity []. The N-terminal portion of Pex22 has a membrane anchoring function, whereas the C-terminal domain harbours its biological activity. The soluble C-terminal domain of Pex22 is essential for peroxisomal biogenesis and efficient monoubiquitination of the import receptor Pex5 [].
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Publication
19091015 | J:153381
 
First Author: Mizuno Y
Year: 2008
Journal: BMC Bioinformatics
Title: Predicted mouse peroxisome-targeted proteins and their actual subcellular locations.
Volume: 9 Suppl 12
Pages: S16
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Publication
9536089 | J:47622
First Author: Ofman R
Year: 1998
Journal: Hum Mol Genet
Title: Acyl-CoA:dihydroxyacetonephosphate acyltransferase: cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2.
Volume: 7
Issue: 5
Pages: 847-53
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Publication
9053836 | J:90270
First Author: Terradillos O
Year: 1997
Journal: Oncogene
Title: The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice.
Volume: 14
Issue: 4
Pages: 395-404
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Publication
19264098 | J:149245
First Author: Miyata N
Year: 2009
Journal: Biochim Biophys Acta
Title: In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes.
Volume: 1793
Issue: 5
Pages: 860-70
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Protein
Q8C437
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
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Protein
O09012
Organism: Mus musculus/domesticus
Length: 639  
Fragment?: false
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Publication
10882522 | J:63597
First Author: Andrée B
Year: 2000
Journal: Dev Biol
Title: Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart.
Volume: 223
Issue: 2
Pages: 371-82
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Protein
F8SLP6
Organism: Mus musculus/domesticus
Length: 626  
Fragment?: false
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Protein
F8SLQ1
Organism: Mus musculus/domesticus
Length: 650  
Fragment?: false
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Protein
F8SLQ3
Organism: Mus musculus/domesticus
Length: 615  
Fragment?: false
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Protein
F8SLP9
Organism: Mus musculus/domesticus
Length: 567  
Fragment?: false
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Protein
F8SLP5
Organism: Mus musculus/domesticus
Length: 648  
Fragment?: false
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Protein
F8SLP7
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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Protein
F8SLQ5
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: false
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Protein
D3Z600
Organism: Mus musculus/domesticus
Length: 632  
Fragment?: false
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Protein
F8SLQ6
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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Protein
F8SLP8
Organism: Mus musculus/domesticus
Length: 602  
Fragment?: false
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Protein
F8SLQ4
Organism: Mus musculus/domesticus
Length: 625  
Fragment?: false
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Protein
D3YYH0
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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Publication
10402463 | -
First Author: Koller A
Year: 1999
Journal: J Cell Biol
Title: Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane.
Volume: 146
Issue: 1
Pages: 99-112
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Publication
22085930 | -
First Author: Williams C
Year: 2012
Journal: EMBO J
Title: Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex.
Volume: 31
Issue: 2
Pages: 391-402
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Protein
Q9D0K1
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: false
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