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Search results 201 to 225 out of 225 for Map2k7

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0.022s

Type

Details

Score

Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

•

UniProt Feature

Begin:	183
Description:	Phosphothreonine; by MAP2K7
Type:	modified residue
End:	183

•

UniProt Feature

Begin:	221
Description:	Phosphothreonine; by MAP2K7
Type:	modified residue
End:	221

•

UniProt Feature

Begin:	183
Description:	Phosphothreonine; by MAP2K7
Type:	modified residue
End:	183

•

Publication

35069705 | J:338778

First Author:	Heinen T
Year:	2021
Journal:	Front Genet
Title:	Evolution of a New Testis-Specific Functional Promoter Within the Highly Conserved Map2k7 Gene of the Mouse.
Volume:	12

Pages:	812139

•

UniProt Feature

Begin:	180
Description:	Phosphothreonine; by MAP2K3, MAP2K4, MAP2K6 and MAP2K7
Type:	modified residue
End:	180

•

Allele

Gt(ROSA)26Sor<tm17(MAP2K7/MAPK8)Jhai> | MGI:5575397

Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 17, Jody Haigh
Allele Type:	Targeted
Attribute String:	Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter

•

Allele

Gt(ROSA)26Sor<tm1(CAG-MAP2K7*/MAPK8,-EGFP)Ftw> | MGI:5494696

Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, F Thomas Wunderlich
Allele Type:	Targeted
Attribute String:	Conditional ready, Constitutively active, Humanized sequence, Inserted expressed sequence, Reporter

•

Publication

11163770 | -

First Author:	Ikeda A
Year:	2001
Journal:	FEBS Lett
Title:	Identification and characterization of functional domains in a mixed lineage kinase LZK.
Volume:	488
Issue:	3
Pages:	190-5

•

Publication

11726277 | -

First Author:	Ikeda A
Year:	2001
Journal:	J Biochem
Title:	Mixed lineage kinase LZK forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway.
Volume:	130
Issue:	6
Pages:	773-81

•

Protein Domain

IPR027258 | MAPKKK13

Type:

Family

Description:

MAP3K13 (also known as leucine zipper-bearing kinase LZK) activates the c-Jun-NH2 terminal kinase (JNK) pathway through activation of the MAP kinase kinase MAP2K7 [, ]. MAP3K13 acts synergistically with peroxiredoxin-3 (PRDX3) to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B []. MAP3K13 forms dimers/oligomers through its dual leucine zipper-like motif, and that this is necessary for activation of the JNK/SAPK pathway [].

•

Publication

31533924 | J:284125

First Author:	Qin Y
Year:	2019
Journal:	Development
Title:	WDR62 is involved in spindle assembly by interacting with CEP170 in spermatogenesis.
Volume:	146
Issue:	20

•

Publication

12492477 | -

First Author:	Masaki M
Year:	2003
Journal:	Eur J Biochem
Title:	Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically.
Volume:	270
Issue:	1
Pages:	76-83

•

Protein Domain

IPR017419 | MAP3K12_MAP3K13

Type:

Family

Description:

This entry represents mitogen-activated protein kinase kinase kinase, types 12/13 (MAP3K12 and MAP3K13), which form part of the mixed lineage kinase (MLK) family. MAP3K12 (also known as leucine-zipper protein kinase (ZPK), dual leucine zipper-bearing kinase (DLK) or MAPK-upstream kinase (MUK)) is a MAPKKK class protein kinase that induces JNK/SAPK activation. MAP3K12 is known to interact with MUK-binding inhibitory protein (MBIP). MBIP contains two tandem leucine-zipper-like motifs; MBIP interacts with one of the two leucine-zipper-like motifs of MAP3K12 and inhibits the activity of MAP3K12 to induce JNK/SAPK activation [, ]. MAP3K12 is autophosphorylated on Ser/Thr in cytosol under basal conditions, and dephosphorylated when membrane-associated.MAP3K13 (also known as leucine zipper-bearing kinase LZK) activates the c-Jun-NH2 terminal kinase (JNK) pathway through activation of the MAP kinase kinase MAP2K7 []. MAP3K13 acts synergistically with peroxiredoxin-3 (PRDX3) to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B [].

•

Publication

30102701 | J:266305

First Author:	Zhou Y
Year:	2018
Journal:	PLoS Genet
Title:	Wdr62 is involved in meiotic initiation via activating JNK signaling and associated with POI in humans.
Volume:	14
Issue:	8
Pages:	e1007463

•

Publication

23349837 | J:195844

First Author:	Pal M
Year:	2013
Journal:	PLoS One
Title:	Alteration of JNK-1 signaling in skeletal muscle fails to affect glucose homeostasis and obesity-associated insulin resistance in mice.
Volume:	8
Issue:	1
Pages:	e54247

•

Genotype

Symbol:	Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Ckmm-cre)5Khn/?
Background:	involves: C57BL/6 * FVB
Zygosity:	cn
Has Mutant Allele:	true

•

Publication

14697235 | -

First Author:	Itoh A
Year:	2004
Journal:	Biochem Biophys Res Commun
Title:	SP3 acts as a positive regulator on the core promoter of human ZPK gene.
Volume:	313
Issue:	3
Pages:	612-8

•

Publication

30566428 | J:273281

First Author:	Xu D
Year:	2018
Journal:	PLoS Biol
Title:	MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis.
Volume:	16
Issue:	12
Pages:	e2006613

•

Publication

25456138 | J:218752

First Author:	Tsaousidou E
Year:	2014
Journal:	Cell Rep
Title:	Distinct Roles for JNK and IKK Activation in Agouti-Related Peptide Neurons in the Development of Obesity and Insulin Resistance.
Volume:	9
Issue:	4
Pages:	1495-506

•

Publication

29106399 | J:252611

First Author:	Awazawa M
Year:	2017
Journal:	Nat Med
Title:	A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle.
Volume:	23
Issue:	12
Pages:	1466-1473

•

Publication

10801814 | -

First Author:	Fukuyama K
Year:	2000
Journal:	J Biol Chem
Title:	MAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinase.
Volume:	275
Issue:	28
Pages:	21247-54

•

Protein

Q1HKZ5

Organism:	Mus musculus/domesticus
Length:	959
Fragment?:	false

•

Protein

Q60700

Organism:	Mus musculus/domesticus
Length:	888
Fragment?:	false

•

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