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Search results 501 to 580 out of 580 for Cd47

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Strain
MGI:6352450 | BALB/cJGpt-Cd47<em1(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7588576 | C57BL/6J-Cd47<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:5903920 | C57BL/6Ncrl-Cd47<em3Idmo>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Cd47<tm1c(KOMP)Mbp> | MGI:6274703
Name: CD47 antigen (Rh-related antigen, integrin-associated signal transducer); targeted mutation 1c, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Conditional ready
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Strain
MGI:6349664 | C57BL/6JGpt-Cd47<em2(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6199071 | B6.129S-Rag1<tm1Mom> Cd47<tm1Fpl> Il2rg<tm1Wjl>/SzJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5609558 | B6.129S-Rag2<tm1Fwa> Cd47<tm1Fpl> Il2rg<tm1Wjl>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5528885 | B6.129(Cg)-Rag2<tm1Fwa> Cd47<tm1Fpl> Il2rg<tm1Cgn>/KhasJ
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Rag2/Rag2 Cd47/Cd47 Il2rg/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Allele
Sirpa<Idd13.2-NOD/ShiLt> | MGI:5827684
 
Name: signal-regulatory protein alpha; insulin dependent diabetes susceptibility 13.2-NOD/ShiLt
Allele Type: QTL
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Strain
MGI:7573074 | B6.Cg-Rag2<tm1Fwa> Sgsh<mps3a> Cd47<tm1Fpl> Il2rg<tm1Wjl>/JnolJ
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Strain
MGI:6865980 | C57BL/6N-A<tm1Brd> Cd47<tm1a(KOMP)Mbp>/Mmucd
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:6770236 | BALB/cJGpt-Sirpa<em1(SIRPA)Gpt> Cd47<em3(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6350333 | C57BL/6JGpt-Pdcd1<em1(PDCD1)Gpt> Cd47<em3(CD47)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6343948 | C57BL/6N-A<tm1Brd> Cd47<tm1c(KOMP)Mbp>/MbpMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:7577158 | C57BL/6JGpt-Sirpa<em2(SIRPA)Gpt> Cd47<em2(CD47)Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR037805 | IgV_CD47
Type: Domain
Description: CD47 was originally identified as integrin-associated protein (IAP). It is a transmembrane glycoprotein that possesses an immunoglobulin variable (IgV) like N-terminal domain, five transmembrane domains and an alternatively spliced C terminus. It functions as a marker of self on erythrocytes, and likely also on other cells, by binding to the inhibitory receptor SIRPalpha []. CD47-induces caspase-independent cell death may be mediated by cytoskeleton reorganisation []. The protein can also act as a thrombospondin receptor [].This entry represents the IgV domain of of CD47. The interaction of CD47 with integrins is dependent on its IgV and transmembrane domains. The IgV domain and transmembrane domain of CD47 have also been found to be sufficient for the association with actin [].
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Publication
23293079 | J:194763
First Author: Yamauchi T
Year: 2013
Journal: Blood
Title: Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.
Volume: 121
Issue: 8
Pages: 1316-25
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Strain
MGI:7382583 | BALB/cJGpt-Pdcd1<em2(PDCD1)Gpt> Sirpa<em2(SIRPA)Gpt> Cd47<em3(CD47)Gpt> Cd274<tm2(CD274)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation, transgenic
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Publication
- | J:239221
     
First Author: Charles River
Year: 2017
Journal: Scientific info. sheet (http://www.criver.com/files/pdfs/rms/ncg/ncg-mouse-scientific--sheet.aspx)
Title: NOD CRISPR Prkdcil2r Gamma (NCG) Triple-Immunodeficient Mouse Model
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Strain
MGI:7329783 | B6.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> II2rg<tm1Wjl>/Kyu
Attribute String: congenic, mutant strain, targeted mutation
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Publication
27499200 | J:327242
First Author: Yurino A
Year: 2016
Journal: Stem Cell Reports
Title: Enhanced Reconstitution of Human Erythropoiesis and Thrombopoiesis in an Immunodeficient Mouse Model with Kit(Wv) Mutations.
Volume: 7
Issue: 3
Pages: 425-438
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Strain
MGI:7329944 | B6.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Il2rg<tm1Wjl> Tg(Krt14-Tslp)#Dfk/Pas
Attribute String: congenic, mutant strain, spontaneous mutation, transgenic, targeted mutation
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Strain
MGI:7329802 | B6.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Kit<W-v> Il2rg<tm1Wjl>/Kyu
Attribute String: congenic, mutant strain, targeted mutation, spontaneous mutation
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Publication
30065364 | J:327313
First Author: Li Y
Year: 2018
Journal: Nat Methods
Title: A human immune system mouse model with robust lymph node development.
Volume: 15
Issue: 8
Pages: 623-630
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Strain
MGI:6474618 | C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn>/Geno
Attribute String: congenic, targeted mutation, mutant strain, QTL
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Strain
MGI:6474620 | C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn> Tg(HLA-A/H2-D/B2M)1Bpe/Geno
Attribute String: congenic, targeted mutation, mutant strain, transgenic, QTL
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Publication
30888052 | J:277140
First Author: Masse-Ranson G
Year: 2019
Journal: Eur J Immunol
Title: Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.
Volume: 49
Issue: 6
Pages: 954-965
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Publication
25646432 | J:220007
First Author: Feng M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.
Volume: 112
Issue: 7
Pages: 2145-50
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Publication
29881378 | J:337307
 
First Author: Salinas-Muñoz L
Year: 2018
Journal: Front Immunol
Title: Estrogen Receptor-Alpha (ESR1) Governs the Lower Female Reproductive Tract Vulnerability to Candida albicans.
Volume: 9
Pages: 1033
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Publication
32814029 | J:305310
First Author: Beguier F
Year: 2020
Journal: Immunity
Title: The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination.
Volume: 53
Issue: 2
Pages: 429-441.e8
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Publication
17982459 | J:127760
First Author: Takenaka K
Year: 2007
Journal: Nat Immunol
Title: Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.
Volume: 8
Issue: 12
Pages: 1313-23
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Publication
26057870 | J:237705
First Author: Alvarez-Zarate J
Year: 2015
Journal: PLoS One
Title: Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.
Volume: 10
Issue: 6
Pages: e0127178
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Publication
32024825 | J:287661
First Author: Sorkin M
Year: 2020
Journal: Nat Commun
Title: Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing.
Volume: 11
Issue: 1
Pages: 722
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Publication
34020945 | J:314143
 
First Author: Guo Y
Year: 2021
Journal: Sci Adv
Title: Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells.
Volume: 7
Issue: 21
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Publication
30664738 | J:274044
First Author: Liu M
Year: 2019
Journal: Nat Immunol
Title: Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal.
Volume: 20
Issue: 3
Pages: 265-275
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Publication
32493933 | J:293407
First Author: Cui L
Year: 2020
Journal: Nat Commun
Title: Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity.
Volume: 11
Issue: 1
Pages: 2795
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Publication
30134171 | J:271121
First Author: Liu X
Year: 2018
Journal: Cell Rep
Title: Dual Targeting of Innate and Adaptive Checkpoints on Tumor Cells Limits Immune Evasion.
Volume: 24
Issue: 8
Pages: 2101-2111
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Publication
31562210 | J:280950
First Author: Gomes AC
Year: 2019
Journal: J Immunol
Title: IFN-γ-Dependent Reduction of Erythrocyte Life Span Leads to Anemia during Mycobacterial Infection.
Volume: 203
Issue: 9
Pages: 2485-2496
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Publication
32198351 | J:286385
First Author: von Roemeling CA
Year: 2020
Journal: Nat Commun
Title: Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
Volume: 11
Issue: 1
Pages: 1508
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Publication
33795678 | J:305272
First Author: Ding X
Year: 2021
Journal: Nat Commun
Title: Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.
Volume: 12
Issue: 1
Pages: 2030
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Publication
35511221 | J:338730
   
First Author: Ren B
Year: 2022
Journal: Elife
Title: Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells.
Volume: 11
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Publication
38200243 | J:346647
First Author: Huang C
Year: 2024
Journal: Nat Cancer
Title: Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47.
Volume: 5
Issue: 3
Pages: 500-516
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Publication
31378988 | J:278786
     
First Author: Labarthe L
Year: 2019
Journal: J Leukoc Biol
Title: Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples.
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Publication
30105024 | J:278727
 
First Author: Lin Y
Year: 2018
Journal: Front Immunol
Title: Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression.
Volume: 9
Pages: 1744
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Publication
31383641 | J:282099
First Author: Jain S
Year: 2019
Journal: Blood
Title: Targeted inhibition of CD47-SIRPα requires Fc-FcγR interactions to maximize activity in T-cell lymphomas.
Volume: 134
Issue: 17
Pages: 1430-1440
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Publication
33232198 | J:345757
First Author: Jeanne A
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Towards the Therapeutic Use of Thrombospondin 1/CD47 Targeting TAX2 Peptide as an Antithrombotic Agent.
Volume: 41
Issue: 1
Pages: e1-e17
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Publication
27697548 | J:345771
 
First Author: Shatos MA
Year: 2016
Journal: Exp Eye Res
Title: Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1(-/-) mice, a model of dry eye.
Volume: 153
Pages: 27-41
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Publication
17890448 | J:129994
First Author: Isenberg JS
Year: 2008
Journal: Blood
Title: Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling.
Volume: 111
Issue: 2
Pages: 613-23
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Publication
24269920 | J:215722
First Author: Iwamoto C
Year: 2014
Journal: Exp Hematol
Title: The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.
Volume: 42
Issue: 3
Pages: 163-171.e1
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Publication
31370677 | J:290149
First Author: Ghimire K
Year: 2019
Journal: FASEB J
Title: Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.
Volume: 33
Issue: 10
Pages: 11528-11540
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Publication
27422603 | J:238666
First Author: Holm CK
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Lack of SIRPα phosphorylation and concomitantly reduced SHP-2-PI3K-Akt2 signaling decrease osteoblast differentiation.
Volume: 478
Issue: 1
Pages: 268-273
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Publication
34097709 | J:310642
First Author: Sarute N
Year: 2021
Journal: PLoS Pathog
Title: Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.
Volume: 17
Issue: 6
Pages: e1009662
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Publication
18635660 | J:145479
First Author: Kobayashi M
Year: 2008
Journal: Endocrinology
Title: Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.
Volume: 149
Issue: 11
Pages: 5662-9
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Publication
12167615 | J:79592
First Author: Yamao T
Year: 2002
Journal: J Biol Chem
Title: Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.
Volume: 277
Issue: 42
Pages: 39833-9
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Publication
36823373 | J:335438
First Author: Niu S
Year: 2023
Journal: Cell Death Differ
Title: Lineage tracing of mutant granulosa cells reveals in vivo protective mechanisms that prevent granulosa cell tumorigenesis.
Volume: 30
Issue: 5
Pages: 1235-1246
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Publication
32541024 | J:291515
First Author: Wang Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.
Volume: 117
Issue: 27
Pages: 15818-15826
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Publication
32286430 | J:289162
First Author: Suh JS
Year: 2020
Journal: Sci Rep
Title: Rosuvastatin Prevents the Exacerbation of Atherosclerosis in Ligature-Induced Periodontal Disease Mouse Model.
Volume: 10
Issue: 1
Pages: 6383
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Publication
16183669 | J:115745
First Author: Ong E
Year: 2005
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Role of phosphatidylinositol 3-kinase-gamma in mediating lung neutrophil sequestration and vascular injury induced by E. coli sepsis.
Volume: 289
Issue: 6
Pages: L1094-103
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Publication
17395782 | J:145404
First Author: Bogdanova A
Year: 2007
Journal: Blood
Title: Enhanced erythro-phagocytosis in polycythemic mice overexpressing erythropoietin.
Volume: 110
Issue: 2
Pages: 762-9
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Publication
12393467 | J:81124
First Author: Mouro-Chanteloup I
Year: 2003
Journal: Blood
Title: Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47.
Volume: 101
Issue: 1
Pages: 338-44
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Publication
16920950 | J:139544
First Author: Ikeda H
Year: 2006
Journal: J Immunol
Title: Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.
Volume: 177
Issue: 5
Pages: 3123-32
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Publication
29158380 | J:255188
First Author: Ring NG
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Volume: 114
Issue: 49
Pages: E10578-E10585
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Publication
32631940 | J:294298
First Author: Huang Y
Year: 2020
Journal: J Neurosci
Title: Synergistic Toll-like Receptor 3/9 Signaling Affects Properties and Impairs Glioma-Promoting Activity of Microglia.
Volume: 40
Issue: 33
Pages: 6428-6443
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Publication
32206775 | J:289543
First Author: Jinnouchi F
Year: 2020
Journal: Blood
Title: A human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells.
Volume: 135
Issue: 19
Pages: 1661-1672
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Publication
33028619 | J:304059
First Author: Kidder K
Year: 2020
Journal: J Immunol
Title: Inflammation Unrestrained by SIRPα Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-γ.
Volume: 205
Issue: 10
Pages: 2821-2833
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Publication
34011631 | J:308275
 
First Author: Roehle K
Year: 2021
Journal: Sci Transl Med
Title: cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes.
Volume: 13
Issue: 594
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Publication
15699129 | J:96557
First Author: Okazawa H
Year: 2005
Journal: J Immunol
Title: Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system.
Volume: 174
Issue: 4
Pages: 2004-11
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Publication
31899207 | J:297297
First Author: Li J
Year: 2020
Journal: Exp Cell Res
Title: TSP1 ameliorates age-related macular degeneration by regulating the STAT3-iNOS signaling pathway.
Volume: 388
Issue: 1
Pages: 111811
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Publication
31883525 | J:291954
First Author: Elberg G
Year: 2019
Journal: J Neuroinflammation
Title: Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury.
Volume: 16
Issue: 1
Pages: 277
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Publication
36353645 | J:331072
 
First Author: Carrillo-Rodríguez P
Year: 2022
Journal: Front Immunol
Title: Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice.
Volume: 13
Pages: 1013236
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Publication
28356441 | J:265376
First Author: Naftali-Shani N
Year: 2017
Journal: Circulation
Title: Left Ventricular Dysfunction Switches Mesenchymal Stromal Cells Toward an Inflammatory Phenotype and Impairs Their Reparative Properties Via Toll-Like Receptor-4.
Volume: 135
Issue: 23
Pages: 2271-2287
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Publication
33133093 | J:341802
 
First Author: Myers DR
Year: 2020
Journal: Front Immunol
Title: Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity.
Volume: 11
Pages: 576310
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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