Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
pig, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
TFG (TRK-fused gene) is localised at endoplasmic reticulum (ER) exit sites and modulates ER export []. It may function at the ER/ERGIC interface to locally concentrate COPII-coated transport carriers and link exit sites on the ER to ERGIC membranes []. It is also an inhibitory regulator of the ubiquitin-proteasome system [, ]. Mutations in the TFG gene cause Okinawa hereditary motor and sensory neuropathy (HMSNO) []and spastic paraplegia 57, autosomal recessive (SPG57) []. |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Beetz C |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure. |
Volume: |
110 |
Issue: |
13 |
Pages: |
5091-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnson A |
Year: |
2015 |
Journal: |
EMBO J |
Title: |
TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization. |
Volume: |
34 |
Issue: |
6 |
Pages: |
811-27 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
220
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishiura H |
Year: |
2012 |
Journal: |
Am J Hum Genet |
Title: |
The TRK-fused gene is mutated in hereditary motor and sensory neuropathy with proximal dominant involvement. |
Volume: |
91 |
Issue: |
2 |
Pages: |
320-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanadome T |
Year: |
2017 |
Journal: |
FEBS J |
Title: |
The calcium-binding protein ALG-2 promotes endoplasmic reticulum exit site localization and polymerization of Trk-fused gene (TFG) protein. |
Volume: |
284 |
Issue: |
1 |
Pages: |
56-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mencinger M |
Year: |
1999 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Characterization of TFG in mus musculus and Caenorhabditis elegans. |
Volume: |
257 |
Issue: |
1 |
Pages: |
67-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yagi T |
Year: |
2014 |
Journal: |
Neurobiol Dis |
Title: |
Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin-proteasome system. |
Volume: |
66 |
|
Pages: |
83-91 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1513028 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:4354860 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Tfg |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1513028 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:4354860 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression is present in the upper, but not the lower, cortical plate. |
Specimen Label: |
Table S5 - Tfg |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1513028 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-08-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4354860 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Tfg |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
131
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
348
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
397
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
389
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
89
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
103
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamotoya T |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity. |
Volume: |
7 |
Issue: |
1 |
Pages: |
13026 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamamotoya T |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases. |
Volume: |
12 |
Issue: |
1 |
Pages: |
1966 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604359 |
Assay Type: |
Northern blot |
Annotation Date: |
2005-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603910 |
|
Stage: |
TS10 |
Assay Id: |
MGI:3604358 |
Age: |
embryonic day 7.0 |
|
|
Specimen Label: |
7 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604359 |
Assay Type: |
Northern blot |
Annotation Date: |
2005-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603918 |
|
Stage: |
TS18 |
Assay Id: |
MGI:3604358 |
Age: |
embryonic day 11.0 |
|
|
Specimen Label: |
11 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604359 |
Assay Type: |
Northern blot |
Annotation Date: |
2005-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603923 |
|
Stage: |
TS23 |
Assay Id: |
MGI:3604358 |
Age: |
embryonic day 15.0 |
|
|
Specimen Label: |
15 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3604359 |
Assay Type: |
Northern blot |
Annotation Date: |
2005-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603925 |
|
Stage: |
TS25 |
Assay Id: |
MGI:3604358 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
17 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640518 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666818 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603918 |
Pattern: |
Regionally restricted |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in limb buds, branchial arches, nasal processes and brain. Staining was weak in the primitive spinal cord and the dorsal root ganglia. Other organs appeared negative. |
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1609218 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611718 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689418 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:228812 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-11-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1668018 |
Pattern: |
Not Specified |
Stage: |
TS18 |
Assay Id: |
MGI:3604362 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
4b |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sima J |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. |
Volume: |
115 |
Issue: |
32 |
Pages: |
8173-8178 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki H |
Year: |
2001 |
Journal: |
Genome Res |
Title: |
Protein-protein interaction panel using mouse full-length cDNAs. |
Volume: |
11 |
Issue: |
10 |
Pages: |
1758-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sansom SN |
Year: |
2009 |
Journal: |
PLoS Genet |
Title: |
The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. |
Volume: |
5 |
Issue: |
6 |
Pages: |
e1000511 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cobellis G |
Year: |
2005 |
Journal: |
Nucleic Acids Res |
Title: |
Tagging genes with cassette-exchange sites. |
Volume: |
33 |
Issue: |
4 |
Pages: |
e44 |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
University of California, Davis |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the University of California, Davis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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UniProt Feature |
Begin: |
379 |
Description: |
TFG box |
Type: |
short sequence motif |
End: |
399 |
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UniProt Feature |
Begin: |
330 |
Description: |
TFG box |
Type: |
short sequence motif |
End: |
350 |
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UniProt Feature |
Begin: |
102 |
Description: |
TFG box |
Type: |
short sequence motif |
End: |
122 |
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UniProt Feature |
Begin: |
250 |
Description: |
TFG box |
Type: |
short sequence motif |
End: |
270 |
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UniProt Feature |
Begin: |
185 |
Description: |
TFG box |
Type: |
short sequence motif |
End: |
205 |
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UniProt Feature |
Begin: |
41 |
Description: |
TFG box |
Type: |
short sequence motif |
End: |
61 |
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