The solute carrier family 10 (SLC10) comprises influx transporters of bile acids, steroidal hormones, various drugs, and several other substrates. Some members of the family are orphan carriers. The name "bile acid transporter family"arose because the first two SLC10 members characterised (NTCP/SLC10A1 and ASBT/SLC10A2) were primarily bile acid transporters [, ].Solute carrier family 10 member 4 (SLC10A4) is a synaptic vesicule monoaminergic and cholinergic associated transporter important for neuromodulation [, ]. SLC10A4 is still regarded an orphan transporter, although a protease-modified variant was recently reported to transport bile acids [].
