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Search results 1 to 100 out of 186 for Pik3cd

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Type Details Score
Publication
30194267 | J:270222
First Author: Wray-Dutra MN
Year: 2018
Journal: J Exp Med
Title: Activated PIK3CD drives innate B cell expansion yet limits B cell-intrinsic immune responses.
Volume: 215
Issue: 10
Pages: 2485-2496
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Publication
30018075 | J:292599
First Author: Avery DT
Year: 2018
Journal: J Exp Med
Title: Germline-activating mutations in PIK3CD compromise B cell development and function.
Volume: 215
Issue: 8
Pages: 2073-2095
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Publication
24634494 | J:210009
First Author: Steinbach EC
Year: 2014
Journal: J Immunol
Title: Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.
Volume: 192
Issue: 8
Pages: 3958-68
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Publication
23820902 | J:250774
First Author: Li Q
Year: 2013
Journal: Mol Endocrinol
Title: Phosphoinositide 3-kinase p110δ mediates estrogen- and FSH-stimulated ovarian follicle growth.
Volume: 27
Issue: 9
Pages: 1468-82
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Publication
22689948 | J:186991
First Author: Law AJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy.
Volume: 109
Issue: 30
Pages: 12165-70
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Publication
36943234 | J:340835
 
First Author: Nguyen T
Year: 2023
Journal: J Exp Med
Title: Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
Volume: 220
Issue: 6
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Publication
36812307 | J:336309
First Author: Ames K
Year: 2023
Journal: Sci Adv
Title: PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cells.
Volume: 9
Issue: 8
Pages: eade8222
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Publication
22020336 | J:196250
First Author: Fransson S
Year: 2012
Journal: Oncogene
Title: p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors.
Volume: 31
Issue: 27
Pages: 3277-86
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Publication
12130661 | J:78412
First Author: Okkenhaug K
Year: 2002
Journal: Science
Title: Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.
Volume: 297
Issue: 5583
Pages: 1031-4
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Publication
18809712 | J:140102
First Author: Guo H
Year: 2008
Journal: J Exp Med
Title: The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation.
Volume: 205
Issue: 10
Pages: 2419-35
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Publication
30127432 | J:282486
First Author: Preite S
Year: 2018
Journal: Nat Immunol
Title: Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity.
Volume: 19
Issue: 9
Pages: 986-1000
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Publication
17015696 | J:139452
First Author: Okkenhaug K
Year: 2006
Journal: J Immunol
Title: The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells.
Volume: 177
Issue: 8
Pages: 5122-8
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Publication
- | J:236693
     
First Author: Zeng M
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for grand_tetons
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Publication
- | J:213049
     
First Author: Arnold C
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for stinger
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Publication
17277138 | J:143983
First Author: Al-Alwan MM
Year: 2007
Journal: J Immunol
Title: Requirement for phosphoinositide 3-kinase p110delta signaling in B cell antigen receptor-mediated antigen presentation.
Volume: 178
Issue: 4
Pages: 2328-35
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Publication
24625684 | J:210223
 
First Author: Low PC
Year: 2014
Journal: Nat Commun
Title: PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model.
Volume: 5
Pages: 3450
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Publication
26711346 | J:265969
First Author: Kieckbusch J
Year: 2015
Journal: Cell Rep
Title: Disrupted PI3K p110δ Signaling Dysregulates Maternal Immune Cells and Increases Fetal Mortality In Mice.
Volume: 13
Issue: 12
Pages: 2817-28
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Publication
28659355 | J:251017
First Author: Okeke EB
Year: 2017
Journal: J Immunol
Title: Deficiency of Phosphatidylinositol 3-Kinase δ Signaling Leads to Diminished Numbers of Regulatory T Cells and Increased Neutrophil Activity Resulting in Mortality Due to Endotoxic Shock.
Volume: 199
Issue: 3
Pages: 1086-1095
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Publication
22479345 | J:224202
First Author: Ying H
Year: 2012
Journal: PLoS One
Title: Genetic or pharmaceutical blockade of phosphoinositide 3-kinase p110δ prevents chronic rejection of heart allografts.
Volume: 7
Issue: 3
Pages: e32892
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Publication
18354181 | J:132989
First Author: Kim MS
Year: 2008
Journal: J Immunol
Title: Activation and function of the mTORC1 pathway in mast cells.
Volume: 180
Issue: 7
Pages: 4586-95
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Publication
23012430 | J:191106
First Author: Stanley AC
Year: 2012
Journal: J Leukoc Biol
Title: Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages.
Volume: 92
Issue: 6
Pages: 1227-39
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Publication
32641742 | J:291986
First Author: Bibby JA
Year: 2020
Journal: Nat Commun
Title: Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate.
Volume: 11
Issue: 1
Pages: 3412
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Publication
34380646 | J:331196
First Author: Olayinka-Adefemi F
Year: 2021
Journal: J Immunol
Title: Critical Roles of Phosphoinositide 3-Kinase δ in the Humoral Immune Response to Trypanosoma congolense Infection.
Volume: 207
Issue: 5
Pages: 1401-1410
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Publication
28108509 | J:241026
First Author: Ahmad S
Year: 2017
Journal: Cancer Res
Title: Differential PI3Kδ Signaling in CD4+ T-cell Subsets Enables Selective Targeting of T Regulatory Cells to Enhance Cancer Immunotherapy.
Volume: 77
Issue: 8
Pages: 1892-1904
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Publication
31363064 | J:287771
First Author: Martínez-Mármol R
Year: 2019
Journal: J Neurosci
Title: p110δ PI3-Kinase Inhibition Perturbs APP and TNFα Trafficking, Reduces Plaque Burden, Dampens Neuroinflammation, and Prevents Cognitive Decline in an Alzheimer's Disease Mouse Model.
Volume: 39
Issue: 40
Pages: 7976-7991
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38182748 | J:344309
First Author: Tzenaki N
Year: 2024
Journal: Commun Biol
Title: A combined opposite targeting of p110δ PI3K and RhoA abrogates skin cancer.
Volume: 7
Issue: 1
Pages: 26
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Publication
17236236 | J:117874
First Author: Nashed BF
Year: 2007
Journal: Eur J Immunol
Title: Role of the phosphoinositide 3-kinase p110delta in generation of type 2 cytokine responses and allergic airway inflammation.
Volume: 37
Issue: 2
Pages: 416-24
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Publication
19843950 | J:156791
First Author: Durand CA
Year: 2009
Journal: J Immunol
Title: Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses.
Volume: 183
Issue: 9
Pages: 5673-84
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Publication
25660021 | J:222882
     
First Author: Doisne JM
Year: 2015
Journal: Cell Rep
Title: Immunomodulation of Selective Naive T Cell Functions by p110δ Inactivation Improves the Outcome of Mismatched Cell Transplantation.
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Publication
31915155 | J:287007
First Author: Wu W
Year: 2020
Journal: Diabetes
Title: PI3Kδ as a Novel Therapeutic Target in Pathological Angiogenesis.
Volume: 69
Issue: 4
Pages: 736-748
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Publication
16179367 | J:126629
First Author: Bilancio A
Year: 2006
Journal: Blood
Title: Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells.
Volume: 107
Issue: 2
Pages: 642-50
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Publication
20081091 | J:158835
First Author: Soond DR
Year: 2010
Journal: Blood
Title: PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans.
Volume: 115
Issue: 11
Pages: 2203-13
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Publication
22808277 | J:189621
First Author: Putz EM
Year: 2012
Journal: PLoS One
Title: PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.
Volume: 7
Issue: 7
Pages: e40852
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Publication
9434625 | J:45005
First Author: Lakkakorpi PT
Year: 1997
Journal: Exp Cell Res
Title: Phosphatidylinositol 3-kinase association with the osteoclast cytoskeleton, and its involvement in osteoclast attachment and spreading.
Volume: 237
Issue: 2
Pages: 296-306
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Publication
20505158 | J:164538
First Author: Ikeda H
Year: 2010
Journal: Blood
Title: PI3K/p110{delta} is a novel therapeutic target in multiple myeloma.
Volume: 116
Issue: 9
Pages: 1460-8
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Publication
22427531 | J:191165
First Author: Kang BN
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.
Volume: 302
Issue: 11
Pages: L1179-91
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30457982 | J:270512
First Author: Dong S
Year: 2019
Journal: J Clin Invest
Title: PI3K p110δ inactivation antagonizes chronic lymphocytic leukemia and reverses T cell immune suppression.
Volume: 129
Issue: 1
Pages: 122-136
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Publication
34220851 | J:341880
 
First Author: Spinelli L
Year: 2021
Journal: Front Immunol
Title: Phosphoinositide 3-Kinase p110 Delta Differentially Restrains and Directs Naïve Versus Effector CD8(+) T Cell Transcriptional Programs.
Volume: 12
Pages: 691997
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Publication
34644563 | J:334660
First Author: Cannons JL
Year: 2021
Journal: Cell Rep
Title: PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8(+) T cells at the expense of central memory.
Volume: 37
Issue: 2
Pages: 109804
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Publication
12774123 | J:83823
First Author: Takahashi K
Year: 2003
Journal: Nature
Title: Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.
Volume: 423
Issue: 6939
Pages: 541-5
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25875604 | J:307462
First Author: Onyilagha C
Year: 2015
Journal: PLoS Negl Trop Dis
Title: The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice.
Volume: 9
Issue: 4
Pages: e0003716
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Publication
35742807 | J:326265
 
First Author: Manda-Handzlik A
Year: 2022
Journal: Int J Mol Sci
Title: Lack of Functional P110δ Affects Expression of Activation Marker CD80 but Does Not Influence Functions of Neutrophils.
Volume: 23
Issue: 12
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14751923 | J:90540
First Author: Puri KD
Year: 2004
Journal: Blood
Title: Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.
Volume: 103
Issue: 9
Pages: 3448-56
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Publication
12235209 | J:79133
First Author: Clayton E
Year: 2002
Journal: J Exp Med
Title: A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation.
Volume: 196
Issue: 6
Pages: 753-63
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16116162 | J:113237
First Author: Webb LM
Year: 2005
Journal: J Immunol
Title: Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.
Volume: 175
Issue: 5
Pages: 2783-7
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18259608 | J:135309
First Author: Jarmin SJ
Year: 2008
Journal: J Clin Invest
Title: T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice.
Volume: 118
Issue: 3
Pages: 1154-64
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Publication
19297623 | J:147569
First Author: Saudemont A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease.
Volume: 106
Issue: 14
Pages: 5795-800
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17277100 | J:144002
First Author: Llorian M
Year: 2007
Journal: J Immunol
Title: The PI3K p110delta is required for down-regulation of RAG expression in immature B cells.
Volume: 178
Issue: 4
Pages: 1981-5
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Publication
24919154 | J:213482
First Author: Ali K
Year: 2014
Journal: Nature
Title: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer.
Volume: 510
Issue: 7505
Pages: 407-411
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18684865 | J:142153
First Author: Zebedin E
Year: 2008
Journal: Blood
Title: Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance.
Volume: 112
Issue: 12
Pages: 4655-64
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Publication
17082571 | J:140501
First Author: Patton DT
Year: 2006
Journal: J Immunol
Title: Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells.
Volume: 177
Issue: 10
Pages: 6598-602
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22586681 | J:193070
First Author: Fruman DA
Year: 2011
Journal: Cancer Discov
Title: PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic.
Volume: 1
Issue: 7
Pages: 562-72
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31216371 | J:280464
First Author: Hao L
Year: 2019
Journal: J Leukoc Biol
Title: Critical role for PI3Kγ-dependent neutrophil reactive oxygen species in WKYMVm-induced microvascular hyperpermeability.
Volume: 106
Issue: 5
Pages: 1117-1127
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15739165 | J:97803
First Author: Thomas MJ
Year: 2005
Journal: Eur J Immunol
Title: Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases.
Volume: 35
Issue: 4
Pages: 1283-91
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18250464 | J:131982
First Author: Ali K
Year: 2008
Journal: J Immunol
Title: Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo.
Volume: 180
Issue: 4
Pages: 2538-44
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17626838 | J:143141
First Author: Ji H
Year: 2007
Journal: Blood
Title: Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation.
Volume: 110
Issue: 8
Pages: 2940-7
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19596993 | J:151583
First Author: Liu D
Year: 2009
Journal: J Immunol
Title: The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.
Volume: 183
Issue: 3
Pages: 1921-33
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16011964 | J:114310
First Author: Senis YA
Year: 2005
Journal: Platelets
Title: Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets.
Volume: 16
Issue: 3-4
Pages: 191-202
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Publication
24009720 | J:206413
First Author: Zotes TM
Year: 2013
Journal: PLoS One
Title: PI3K p110δ is expressed by gp38(-)CD31(+) and gp38(+)CD31(+) spleen stromal cells and regulates their CCL19, CCL21, and LTβR mRNA levels.
Volume: 8
Issue: 8
Pages: e72960
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Publication
27843137 | J:241805
First Author: Carter MJ
Year: 2017
Journal: Leukemia
Title: PI3Kδ inhibition elicits anti-leukemic effects through Bim-dependent apoptosis.
Volume: 31
Issue: 6
Pages: 1423-1433
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17644738 | J:149123
First Author: Kim N
Year: 2007
Journal: Blood
Title: The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion.
Volume: 110
Issue: 9
Pages: 3202-8
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16304053 | J:125791
First Author: Swat W
Year: 2006
Journal: Blood
Title: Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival.
Volume: 107
Issue: 6
Pages: 2415-22
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18412166 | J:134324
First Author: Randis TM
Year: 2008
Journal: Eur J Immunol
Title: Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils.
Volume: 38
Issue: 5
Pages: 1215-24
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Publication
16114097 | J:113491
First Author: Glassford J
Year: 2005
Journal: Eur J Immunol
Title: Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.
Volume: 35
Issue: 9
Pages: 2748-61
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Publication
12446777 | J:80614
First Author: Jou ST
Year: 2002
Journal: Mol Cell Biol
Title: Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.
Volume: 22
Issue: 24
Pages: 8580-91
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20200404 | J:162269
First Author: Beer-Hammer S
Year: 2010
Journal: J Leukoc Biol
Title: The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.
Volume: 87
Issue: 6
Pages: 1083-95
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Publication
27442134 | J:282980
First Author: Mothes B
Year: 2016
Journal: PLoS One
Title: p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.
Volume: 11
Issue: 7
Pages: e0159310
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17723215 | J:124330
First Author: Tassi I
Year: 2007
Journal: Immunity
Title: p110gamma and p110delta phosphoinositide 3-kinase signaling pathways synergize to control development and functions of murine NK cells.
Volume: 27
Issue: 2
Pages: 214-27
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21390257 | J:171724
First Author: Patton DT
Year: 2011
Journal: PLoS One
Title: The PI3K p110δ regulates expression of CD38 on regulatory T cells.
Volume: 6
Issue: 3
Pages: e17359
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Publication
27859053 | J:246248
First Author: Jayachandran N
Year: 2017
Journal: Eur J Immunol
Title: B-cell-intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice.
Volume: 47
Issue: 2
Pages: 280-290
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15769890 | J:107472
First Author: Puri KD
Year: 2005
Journal: Blood
Title: The role of endothelial PI3Kgamma activity in neutrophil trafficking.
Volume: 106
Issue: 1
Pages: 150-7
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17632516 | J:123408
First Author: Wang HB
Year: 2007
Journal: Nat Immunol
Title: P-selectin primes leukocyte integrin activation during inflammation.
Volume: 8
Issue: 8
Pages: 882-92
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26740009 | J:339385
First Author: Garçon F
Year: 2016
Journal: Immunol Cell Biol
Title: PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1.
Volume: 94
Issue: 5
Pages: 486-95
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19451552 | J:150750
First Author: Gollmer K
Year: 2009
Journal: Blood
Title: CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.
Volume: 114
Issue: 3
Pages: 580-8
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21487106 | J:185999
First Author: Kulkarni S
Year: 2011
Journal: Sci Signal
Title: PI3Kβ plays a critical role in neutrophil activation by immune complexes.
Volume: 4
Issue: 168
Pages: ra23
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24043760 | J:204070
First Author: Soler A
Year: 2013
Journal: J Exp Med
Title: Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.
Volume: 210
Issue: 10
Pages: 1937-45
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23024273 | J:190607
First Author: Roller A
Year: 2012
Journal: J Immunol
Title: Blockade of phosphatidylinositol 3-kinase PI3Kδ or PI3Kγ reduces IL-17 and ameliorates imiquimod-induced psoriasis-like dermatitis.
Volume: 189
Issue: 9
Pages: 4612-20
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27531651 | J:259189
First Author: Houslay DM
Year: 2016
Journal: Sci Signal
Title: Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.
Volume: 9
Issue: 441
Pages: ra82
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22422878 | J:184069
First Author: Zhang TT
Year: 2012
Journal: J Immunol
Title: p110δ phosphoinositide 3-kinase represses IgE switch by potentiating BCL6 expression.
Volume: 188
Issue: 8
Pages: 3700-8
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Publication
15834429 | J:98315
First Author: Jackson SP
Year: 2005
Journal: Nat Med
Title: PI 3-kinase p110beta: a new target for antithrombotic therapy.
Volume: 11
Issue: 5
Pages: 507-14
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Publication
18786920 | J:143388
First Author: Konrad S
Year: 2008
Journal: J Biol Chem
Title: Phosphoinositide 3-kinases gamma and delta, linkers of coordinate C5a receptor-Fcgamma receptor activation and immune complex-induced inflammation.
Volume: 283
Issue: 48
Pages: 33296-303
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Publication
31120863 | J:336308
 
First Author: Hemmati S
Year: 2019
Journal: JCI Insight
Title: PI3 kinase alpha and delta promote hematopoietic stem cell activation.
Volume: 5
Issue: 13
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Publication
9235916 | J:42042
First Author: Chantry D
Year: 1997
Journal: J Biol Chem
Title: p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes.
Volume: 272
Issue: 31
Pages: 19236-41
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15496927 | J:93235
First Author: Ali K
Year: 2004
Journal: Nature
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