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Search results 201 to 271 out of 271 for Hsf2bp

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0.024s
Type Details Score
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12363
Specimen Label: GUDMAP:12363
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12364
Specimen Label: GUDMAP:12364
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12363
Specimen Label: GUDMAP:12363
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12364
Specimen Label: GUDMAP:12364
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12363
Specimen Label: GUDMAP:12363
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12363
Specimen Label: GUDMAP:12363
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12364
Specimen Label: GUDMAP:12364
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1738322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Image: MY287; Specimen C1607
Specimen Label: MY287; Specimen C1607
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5001991
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542545
Age: embryonic day 15.5
Image: GUDMAP:12363
Specimen Label: GUDMAP:12363
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4428248
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5420943
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: MY287; Specimen C1607
Detected: false
Specimen Num: 1
Publication
First Author: Zhang J
Year: 2020
Journal: Nat Commun
Title: The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells.
Volume: 11
Issue: 1
Pages: 2055
Publication
First Author: Dahlet T
Year: 2021
Journal: Nat Commun
Title: E2F6 initiates stable epigenetic silencing of germline genes during embryonic development.
Volume: 12
Issue: 1
Pages: 3582
Publication
First Author: Zhang J
Year: 2019
Journal: Nat Commun
Title: A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination.
Volume: 10
Issue: 1
Pages: 722
Publication
First Author: Guan Y
Year: 2022
Journal: Nucleic Acids Res
Title: SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.
Volume: 50
Issue: 9
Pages: 5129-5144
Publication
First Author: Davisson MT
Year: 2001
Journal: Genomics
Title: Evolutionary breakpoints on human chromosome 21.
Volume: 78
Issue: 1-2
Pages: 99-106
Publication
First Author: Gitton Y
Year: 2002
Journal: Nature
Title: A gene expression map of human chromosome 21 orthologues in the mouse.
Volume: 420
Issue: 6915
Pages: 586-90
Publication
First Author: Reymond A
Year: 2002
Journal: Nature
Title: Human chromosome 21 gene expression atlas in the mouse.
Volume: 420
Issue: 6915
Pages: 582-6
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Ghouil R
Year: 2021
Journal: Nat Commun
Title: BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination.
Volume: 12
Issue: 1
Pages: 4605
Interaction Experiment
Description: HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.
Allele
Name: heat shock transcription factor 2 binding protein; endonuclease-mediated mutation 2, Alberto M Pendas
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Hypomorph
Genotype
Symbol: Hsf2bp/Hsf2bp
Background: involves: C57BL/6J * CBA/J
Zygosity: hm
Has Mutant Allele: true
DO Term
Protein
Organism: Mus musculus/domesticus
Length: 600  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 106  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 605  
Fragment?: false
Protein Domain
Type: Family
Description: Brme1 (also known as Meiok21) is a component of meiotic recombination bridges involved in meiotic double-strand break repair [, ]. The C-terminal domain of Brme1 physically interacts with the N-terminal domain of HSF2BP []. BRME1 facilitates the loading of RAD51 and DMC1 recombinases onto DSBs (DNA double-strand breaks) through interaction with MEILB2/HSF2BP and replacing ssDNA binding proteins []. Brme1 is highly expressed in mice testes and fetal ovaries. Knockout of Brme1 results in male mice infertility [].