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Search results 201 to 300 out of 415 for Cad

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Type Details Score
Publication
10932250 | J:63880
First Author: Otomo T
Year: 2000
Journal: Nat Struct Biol
Title: Structure of the heterodimeric complex between CAD domains of CAD and ICAD.
Volume: 7
Issue: 8
Pages: 658-62
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Publication
9422513 | J:45124
First Author: Sakahira H
Year: 1998
Journal: Nature
Title: Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.
Volume: 391
Issue: 6662
Pages: 96-9
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Publication
14557248 | J:273504
First Author: Cho SG
Year: 2003
Journal: J Cell Biol
Title: Identification of a novel antiapoptotic protein that antagonizes ASK1 and CAD activities.
Volume: 163
Issue: 1
Pages: 71-81
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Publication
23667179 | J:199587
First Author: Erbilgin A
Year: 2013
Journal: J Lipid Res
Title: Identification of CAD candidate genes in GWAS loci and their expression in vascular cells.
Volume: 54
Issue: 7
Pages: 1894-905
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Publication
8100805 | J:12754
First Author: Bertoni L
Year: 1993
Journal: Genomics
Title: Localization of the Chinese hamster CAD gene reveals homology between human chromosome 2p and Chinese hamster 7q.
Volume: 16
Issue: 3
Pages: 779-81
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Publication
9407011 | J:44810
First Author: Sun D
Year: 1997
Journal: J Neurobiol
Title: Identification of a phylogenetically conserved Sug1 CAD family member that is differentially expressed in the mouse nervous system.
Volume: 33
Issue: 7
Pages: 877-90
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Heritable Phenotypic Marker
MGI:88242 | Cgct
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Publication
11382760 | -
First Author: Wang CW
Year: 2001
Journal: J Biol Chem
Title: Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways.
Volume: 276
Issue: 32
Pages: 30442-51
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Publication
16247502 | -
 
First Author: Yorimitsu T
Year: 2005
Journal: Cell Death Differ
Title: Autophagy: molecular machinery for self-eating.
Volume: 12 Suppl 2
Pages: 1542-52
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GO Term
GO:0045551 | cinnamyl-alcohol dehydrogenase activity
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Publication
10764577 | -
First Author: Uegaki K
Year: 2000
Journal: J Mol Biol
Title: Structure of the CAD domain of caspase-activated DNase and interaction with the CAD domain of its inhibitor.
Volume: 297
Issue: 5
Pages: 1121-8
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Protein
O54788
Organism: Mus musculus/domesticus
Length: 344  
Fragment?: false
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GO Term
GO:0047613 | aconitate decarboxylase activity
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Protein
P54987
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
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Publication
7907330 | -
First Author: Guy HI
Year: 1994
Journal: J Biol Chem
Title: Cloning, expression, and functional interactions of the amidotransferase domain of mammalian CAD carbamyl phosphate synthetase.
Volume: 269
Issue: 10
Pages: 7702-8
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Protein
O54786
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
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Protein
O54786-2
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
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Protein Coding Gene
MGI:1196287 | Dffb
Type: protein_coding_gene
Organism: mouse, laboratory
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DO Term
DOID:0080419 | developmental and epileptic encephalopathy 50
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HT Experiment
E-GEOD-49937 | Expression data from the hearts of a mouse model of spontaneous myocardial infarction
Series Id: GSE49937
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
31548418 | J:325954
First Author: Chen F
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.
Volume: 116
Issue: 41
Pages: 20644-20654
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Publication
9564035 | J:47647
First Author: Inohara N
Year: 1998
Journal: EMBO J
Title: CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor.
Volume: 17
Issue: 9
Pages: 2526-33
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Protein
O70303
Organism: Mus musculus/domesticus
Length: 219  
Fragment?: false
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Protein
P56198
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
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Protein
Q3V4D3
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Protein
E9QMZ0
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: false
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Protein
D3Z1A6
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Publication
15149602 | -
First Author: Woo EJ
Year: 2004
Journal: Mol Cell
Title: Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway.
Volume: 14
Issue: 4
Pages: 531-9
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Publication
10619428 | -
First Author: Lugovskoy AA
Year: 1999
Journal: Cell
Title: Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis.
Volume: 99
Issue: 7
Pages: 747-55
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Protein Domain
IPR036148 | MmgE/PrpD_sf
Type: Homologous_superfamily
Description: MmgE/PrpD superfamily members include 2-methylcitrate dehydratase (PrpD; ) and citrate/2-methylcitrate dehydratase MmgE. PrpD is required for propionate catabolism, catalysing the third step of the 2-methylcitric acid cycle []. This enzyme consists of two domains: a large domain with an all-helical fold and a smaller domain that folds into an alpha beta domain []. Cis-aconitic acid decarboxylase (CAD) shares high identity with proteins of the MmgE/PrpD family. CAD is essential for itaconic acid production in Aspergillus terreus [].
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Protein Domain
IPR003508 | CIDE-N_dom
Type: Domain
Description: The CIDE-N or CAD domain is a ~78 amino acid protein-protein interaction domain in the N-terminal part of Cell death-Inducing DFF45-like Effector (CIDE) proteins, involved in apoptosis. At the final stage of programmed cell death, chromosomal DNA is degraded into fragments by Caspase-activated DNase (CAD), also named DNA fragmentation factor 40kDa (DFF40). In normal cells CAD/DFF40 is completely inhibited by its binding to DFF45 or Inhibitor of CAD (ICAD). Apoptotic stimuli provoke cleavage of ICAD/DFF45 by caspases, resulting in self-assembly of CAD/DFF40 into the active dimer [].Both CAD/DFF40 and ICAD/DFF45 possess an N-terminal CIDE-N domain that is involved in their interaction. The name of the CIDE-N domain refers to the CIDE proteins and CAD, where the domain forms the N-terminal part [, ]. The CIDE-N domains from different proteins can interact, e.g. CIDE-N of CIDE-B and ICAD/DFF45 with CIDE-N of CAD/DFF40, and such interactions can also be needed for proper folding [, ].Tertiary structures show that the CIDE-N domain forms an alpha/beta roll fold of five β-strands forming a single, mixed parallel/anti-parallel β-sheet with one []or two [, ]α-helices packed against the sheet. Binding surfaces of the CIDE-N domain form a central hydrophobic cluster, while specific binding interfaces can be formed by charged patches.Some proteins known to contain a CIDE-N domain include:Mammalian DNA fragmentation factor 40kDa (DFF40) or Caspase-activated deoxyribonuclease (CAD), an endonuclease that induces DNA fragmentation and chromatin condensation during apoptosis. The degradation of chromosomal DNA by CAD/DFF40 will kill the cells.Mammalian DNA fragmentation factor 45kDa (DFF45) or Inhibitor of CAD (ICAD), which controls the activity and proper folding of CAD/DFF40. Mammalian CIDE-A and CIDE-B, activators of cell death and DNA fragmentation that can be inhibited by ICAD/DFF45. In contrast with CAD and ICAD, the CIDE proteins are expressed in a highly restricted way and show pronounced tissue specificity.Fruit fly DNAation factor DREP1, a DFF45 homologue that can inhibit CIDE-A-induced apoptosis.
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Protein
A0A0R4J027
Organism: Mus musculus/domesticus
Length: 488  
Fragment?: false
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Publication
16934291 | -
First Author: Lohkamp B
Year: 2006
Journal: J Mol Biol
Title: Three-dimensional structure of iminodisuccinate epimerase defines the fold of the MmgE/PrpD protein family.
Volume: 362
Issue: 3
Pages: 555-66
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Publication
18584171 | -
First Author: Kanamasa S
Year: 2008
Journal: Appl Microbiol Biotechnol
Title: Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus.
Volume: 80
Issue: 2
Pages: 223-9
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Publication
- | J:13668
 
First Author: Searle AG
Year: 1975
Journal: Mouse News Lett
Title: Ca and med.
Volume: 52
Pages: 35
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Protein
O70302
Organism: Mus musculus/domesticus
Length: 217  
Fragment?: false
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Publication
11371636 | -
First Author: Zhou P
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.
Volume: 98
Issue: 11
Pages: 6051-5
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Publication
21308846 | -
First Author: Eichinger A
Year: 2011
Journal: Protein Sci
Title: Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family.
Volume: 20
Issue: 4
Pages: 656-69
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Protein Domain
IPR005656 | MmgE_PrpD
Type: Family
Description: This entry represents proteins from the MmgE/PrpD family, which includes 2-methylcitrate dehydratase (PrpD; ). PrpD is required for propionate catabolism, catalysing the third step of the 2-methylcitric acid cycle []. This enzyme consists of two domains: a large domain with an all-helical fold and a smaller domain that folds into an alpha+beta domain []. Cis-aconitic acid decarboxylase (CAD) shares high identity with proteins of the MmgE/PrpD family. CAD is essential for itaconic acid production in Aspergillus terreus []. Citrate/2-methylcitrate dehydratase from Bacillus subtilis is involved in the tricarboxylic acid (TCA) and methylcitric acid cycles as it has both 2-methylcitrate dehydratase and citrate dehydratase activities [].
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Protein Domain
IPR042188 | MmgE/PrpD_sf_2
Type: Homologous_superfamily
Description: MmgE/PrpD superfamily members include 2-methylcitrate dehydratase (PrpD; ) and citrate/2-methylcitrate dehydratase MmgE. PrpD is required for propionate catabolism, catalysing the third step of the 2-methylcitric acid cycle []. This enzyme consists of two domains: a large domain with an all-helical fold and a smaller domain that folds into an alpha beta domain []. Cis-aconitic acid decarboxylase (CAD) shares high identity with proteins of the MmgE/PrpD family. CAD is essential for itaconic acid production in Aspergillus terreus [].This superfamily represents the small domain found in PrpD.
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Protein Domain
IPR042183 | MmgE/PrpD_sf_1
Type: Homologous_superfamily
Description: MmgE/PrpD superfamily members include 2-methylcitrate dehydratase (PrpD; ) and citrate/2-methylcitrate dehydratase MmgE. PrpD is required for propionate catabolism, catalysing the third step of the 2-methylcitric acid cycle []. This enzyme consists of two domains: a large domain with an all-helical fold and a smaller domain that folds into an alpha beta domain []. Cis-aconitic acid decarboxylase (CAD) shares high identity with proteins of the MmgE/PrpD family. CAD is essential for itaconic acid production in Aspergillus terreus [].This superfamily represents the large domain found in PrpD.
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Protein Domain
IPR040970 | CadC_C1
Type: Domain
Description: CadC is an integral membrane protein of 512 amino acids comprising an N-terminal cytoplasmic DNA-binding domain, a transmembrane helix, and a C-terminal periplasmic domain. CadC belongs to the ToxR-like regulators that encompass biochemically non-modified one-component systems with similar gross topology, including several low pH-induced transcription regulators. Structural analysis of the C-terminal periplasmic domain indicates that it resembles the sensory domain of a (pH-activated) ToxR-like regulator. Furthermore, it is composed of two subdomains with a cavity at their interface that is suited to accommodate cadaverine, the feedback inhibitor of the Cad system. This is the N-terminal subdomain of the C-terminal periplasmic domain. It is composed of five-stranded β-sheets [].
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Protein Domain
IPR045336 | MmgE_PrpD_N
Type: Domain
Description: This entry represents the N-terminal domain of 2-methylcitrate dehydratase PrpD.PrpD is required for propionate catabolism, catalysing the third step of the 2-methylcitric acid cycle []. This enzyme consists of two domains: a large domain with an all-helical fold and a smaller domain that folds into an α/β domain []. Cis-aconitic acid decarboxylase (CAD) shares high identity with proteins of the MmgE/PrpD family []. CAD is essential for itaconic acid production in Aspergillus terreus []. Citrate/2-methylcitrate dehydratase from Bacillus subtilis is involved in the tricarboxylic acid (TCA) and methylcitric acid cycles as it has both 2-methylcitrate dehydratase and citrate dehydratase activities [].
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Protein Domain
IPR045337 | MmgE_PrpD_C
Type: Domain
Description: This entry represents the C-terminal domain of 2-methylcitrate dehydratase PrpD.PrpD is required for propionate catabolism, catalysing the third step of the 2-methylcitric acid cycle []. This enzyme consists of two domains: a large domain with an all-helical fold and a smaller domain that folds into an α/β domain []. Cis-aconitic acid decarboxylase (CAD) shares high identity with proteins of the MmgE/PrpD family []. CAD is essential for itaconic acid production in Aspergillus terreus []. Citrate/2-methylcitrate dehydratase from Bacillus subtilis is involved in the tricarboxylic acid (TCA) and methylcitric acid cycles as it has both 2-methylcitrate dehydratase and citrate dehydratase activities [].
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Publication
17218958 | J:139290
First Author: Shiokawa D
Year: 2007
Journal: Cell Death Differ
Title: Stage-specific expression of DNasegamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.
Volume: 14
Issue: 5
Pages: 992-1000
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Publication
10945464 | J:63395
First Author: Sakao Y
Year: 2000
Journal: Genomics
Title: Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting.
Volume: 67
Issue: 1
Pages: 1-7
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Publication
23213448 | J:184889
First Author: Wu KS
Year: 2012
Journal: Biol Open
Title: CPAP is required for cilia formation in neuronal cells.
Volume: 1
Issue: 6
Pages: 559-65
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Publication
36792607 | J:336289
First Author: Kim HJ
Year: 2023
Journal: Nat Commun
Title: Molecular mechanisms of coronary artery disease risk at the PDGFD locus.
Volume: 14
Issue: 1
Pages: 847
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Publication
36122209 | J:329211
First Author: Liu F
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic β-catenin stimulation of AKT2-CAD-mediated pyrimidine synthesis is targetable vulnerability in liver cancer.
Volume: 119
Issue: 39
Pages: e2202157119
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Publication
26489464 | J:269831
First Author: Srivastava R
Year: 2015
Journal: Cell Rep
Title: Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease.
Volume: 13
Issue: 4
Pages: 746-759
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Publication
15850779 | J:97973
First Author: Kumar AP
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Statins downregulate myeloperoxidase gene expression in macrophages.
Volume: 331
Issue: 2
Pages: 442-51
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Publication
35383158 | J:325746
First Author: Rohlfing AK
Year: 2022
Journal: Nat Commun
Title: ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury.
Volume: 13
Issue: 1
Pages: 1823
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Publication
35700355 | J:331821
First Author: Qin C
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis.
Volume: 119
Issue: 26
Pages: e2122897119
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Publication
31255286 | J:291082
First Author: Watanabe T
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Cell-free DNA in blood circulation is generated by DNase1L3 and caspase-activated DNase.
Volume: 516
Issue: 3
Pages: 790-795
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Publication
19541853 | J:153451
First Author: Yan B
Year: 2009
Journal: Carcinogenesis
Title: Increased skin carcinogenesis in caspase-activated DNase knockout mice.
Volume: 30
Issue: 10
Pages: 1776-80
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Publication
23429704 | J:193963
First Author: Robitaille AM
Year: 2013
Journal: Science
Title: Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis.
Volume: 339
Issue: 6125
Pages: 1320-3
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Publication
15823561 | J:97432
First Author: Guo H
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Specific disruption of smooth muscle caldesmon expression in mice.
Volume: 330
Issue: 4
Pages: 1132-7
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Publication
10716943 | J:61087
First Author: McIlroy D
Year: 2000
Journal: Genes Dev
Title: An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes.
Volume: 14
Issue: 5
Pages: 549-58
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Publication
23429703 | J:193964
First Author: Ben-Sahra I
Year: 2013
Journal: Science
Title: Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.
Volume: 339
Issue: 6125
Pages: 1323-8
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Publication
24046453 | J:211216
First Author: Jang SM
Year: 2013
Journal: J Cell Sci
Title: Sox4-mediated caldesmon expression facilitates differentiation of skeletal myoblasts.
Volume: 126
Issue: Pt 22
Pages: 5178-88
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Publication
31201301 | J:283495
First Author: AlSiraj Y
Year: 2019
Journal: Nat Commun
Title: XX sex chromosome complement promotes atherosclerosis in mice.
Volume: 10
Issue: 1
Pages: 2631
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Publication
- | J:23108
 
First Author: Beechey CV
Year: 1976
Journal: Mouse News Lett
Title: T(7;15)9H
Volume: 54
Pages: 38
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Publication
11782506 | -
First Author: Blank L
Year: 2002
Journal: Microbiology
Title: AcnC of Escherichia coli is a 2-methylcitrate dehydratase (PrpD) that can use citrate and isocitrate as substrates.
Volume: 148
Issue: Pt 1
Pages: 133-46
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Publication
9422506 | J:45015
First Author: Enari M
Year: 1998
Journal: Nature
Title: A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.
Volume: 391
Issue: 6662
Pages: 43-50
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Publication
8603043 | J:57555
First Author: Choi HS
Year: 1996
Journal: J Steroid Biochem Mol Biol
Title: A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily.
Volume: 56
Issue: 1-6 Spec No
Pages: 23-30
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Publication
8247017 | J:14765
First Author: Hutton JC
Year: 1993
Journal: Mol Endocrinol
Title: Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.
Volume: 7
Issue: 9
Pages: 1151-60
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Publication
25384971 | J:221514
First Author: Makowski SL
Year: 2015
Journal: Mol Cell Biol
Title: A protease-independent function for SPPL3 in NFAT activation.
Volume: 35
Issue: 2
Pages: 451-67
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Publication
23665474 | J:199589
First Author: Zheng Y
Year: 2013
Journal: Dev Biol
Title: A distant, cis-acting enhancer drives induction of Arf by Tgfβ in the developing eye.
Volume: 380
Issue: 1
Pages: 49-57
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Publication
28883612 | J:255740
First Author: Lee AS
Year: 2017
Journal: Sci Rep
Title: Human electronegative low-density lipoprotein modulates cardiac repolarization via LOX-1-mediated alteration of sarcolemmal ion channels.
Volume: 7
Issue: 1
Pages: 10889
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Publication
16639078 | J:112085
First Author: Castellani LW
Year: 2006
Journal: J Lipid Res
Title: Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males.
Volume: 47
Issue: 7
Pages: 1366-77
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Publication
26367277 | J:243099
First Author: Oberoi R
Year: 2015
Journal: PLoS One
Title: Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease.
Volume: 10
Issue: 9
Pages: e0137924
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Publication
20577049 | J:163781
First Author: Yang X
Year: 2010
Journal: J Clin Invest
Title: Identification and validation of genes affecting aortic lesions in mice.
Volume: 120
Issue: 7
Pages: 2414-22
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Publication
33630758 | J:305798
 
First Author: Kasikara C
Year: 2021
Journal: J Clin Invest
Title: Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.
Volume: 131
Issue: 8
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Publication
24082102 | J:201999
First Author: Tsukamoto K
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease.
Volume: 110
Issue: 42
Pages: 17023-8
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Publication
36696485 | J:335298
First Author: Guo H
Year: 2023
Journal: Sci Transl Med
Title: SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant.
Volume: 15
Issue: 680
Pages: eabp9952
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Publication
34849650 | J:331761
First Author: Zhu QM
Year: 2022
Journal: Cardiovasc Res
Title: Endothelial ARHGEF26 is an angiogenic factor promoting VEGF signalling.
Volume: 118
Issue: 13
Pages: 2833-2846
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Publication
30183330 | J:288886
First Author: Cui H
Year: 2019
Journal: Am J Respir Cell Mol Biol
Title: Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury.
Volume: 60
Issue: 2
Pages: 167-178
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Publication
31359001 | J:306619
First Author: Wirka RC
Year: 2019
Journal: Nat Med
Title: Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Volume: 25
Issue: 8
Pages: 1280-1289
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Publication
18025244 | J:154899
First Author: Frisoni L
Year: 2007
Journal: J Immunol
Title: Lack of chromatin and nuclear fragmentation in vivo impairs the production of lupus anti-nuclear antibodies.
Volume: 179
Issue: 11
Pages: 7959-66
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Publication
28007744 | J:271829
 
First Author: Chao ML
Year: 2016
Journal: J Am Heart Assoc
Title: Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice.
Volume: 5
Issue: 12
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Publication
22952653 | J:191664
First Author: Schurgers LJ
Year: 2012
Journal: PLoS One
Title: Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype.
Volume: 7
Issue: 8
Pages: e43229
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•
•
•
•
Publication
26790473 | J:255957
First Author: Watanabe K
Year: 2016
Journal: Cardiovasc Res
Title: Counteractive effects of omentin-1 against atherogenesis†.
Volume: 110
Issue: 1
Pages: 118-28
•
•
•
•
•
Publication
20173736 | J:158126
First Author: Visel A
Year: 2010
Journal: Nature
Title: Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice.
Volume: 464
Issue: 7287
Pages: 409-12
•
•
•
•
•
Publication
31585505 | J:298723
First Author: Chen Y
Year: 2019
Journal: FASEB J
Title: Deficiency in the short-chain acyl-CoA dehydrogenase protects mice against diet-induced obesity and insulin resistance.
Volume: 33
Issue: 12
Pages: 13722-13733
•
•
•
•
•
Publication
20421368 | J:161330
First Author: Zhang L
Year: 2010
Journal: Hum Mol Genet
Title: Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies.
Volume: 19
Issue: 14
Pages: 2754-66
•
•
•
•
•
Publication
20814021 | J:178192
First Author: Dart ML
Year: 2010
Journal: Circ Res
Title: Interleukin-17-dependent autoimmunity to collagen type V in atherosclerosis.
Volume: 107
Issue: 9
Pages: 1106-16
•
•
•
•
•
Publication
30811493 | J:273882
First Author: Mihailovic PM
Year: 2019
Journal: PLoS One
Title: Keratin 8 is a potential self-antigen in the coronary artery disease immunopeptidome: A translational approach.
Volume: 14
Issue: 2
Pages: e0213025
•
•
•
•
•
Publication
23189122 | J:195455
First Author: Zhu J
Year: 2012
Journal: PLoS One
Title: Regulation of microRNA-155 in atherosclerotic inflammatory responses by targeting MAP3K10.
Volume: 7
Issue: 11
Pages: e46551
•
•
•
•
•
Publication
17664290 | J:125950
First Author: Luchtefeld M
Year: 2007
Journal: J Exp Med
Title: Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man.
Volume: 204
Issue: 8
Pages: 1935-44
•
•
•
•
•
Publication
31530895 | J:285417
First Author: Flanagan TW
Year: 2019
Journal: Sci Rep
Title: Activation of 5-HT2 Receptors Reduces Inflammation in Vascular Tissue and Cholesterol Levels in High-Fat Diet-Fed Apolipoprotein E Knockout Mice.
Volume: 9
Issue: 1
Pages: 13444
•
•
•
•
•
Publication
17116228 | J:121118
First Author: Do T
Year: 2007
Journal: J Neurochem
Title: Brain-derived neurotrophic factor regulates the expression of D1 dopamine receptors.
Volume: 100
Issue: 2
Pages: 416-28
•
•
•
•
•
Publication
30444878 | J:268059
First Author: Nanda V
Year: 2018
Journal: PLoS Genet
Title: Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Volume: 14
Issue: 11
Pages: e1007755
•
•
•
•
•
Publication
31584065 | J:295183
First Author: Douglas G
Year: 2020
Journal: Cardiovasc Res
Title: A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.
Volume: 116
Issue: 11
Pages: 1863-1874
•
•
•
•
•
Publication
23986516 | J:202998
First Author: Deng M
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Amino acid mutations in the caldesmon COOH-terminal functional domain increase force generation in bladder smooth muscle.
Volume: 305
Issue: 10
Pages: F1455-65
•
•
•
•
•
Publication
14622145 | J:89660
First Author: Dandoy-Dron F
Year: 2003
Journal: Eur J Neurosci
Title: Scrg1, a novel protein of the CNS is targeted to the large dense-core vesicles in neuronal cells.
Volume: 18
Issue: 9
Pages: 2449-59
•
•
•
•
•
Publication
16371656 | J:105232
First Author: Sousa AD
Year: 2006
Journal: J Cell Sci
Title: Myo10 in brain: developmental regulation, identification of a headless isoform and dynamics in neurons.
Volume: 119
Issue: Pt 1
Pages: 184-94
•
•
•
•
•
Publication
22727028 | J:200478
First Author: Kutscher D
Year: 2012
Journal: FEBS J
Title: Identification of ICAD-derived peptides capable of inhibiting caspase-activated DNase.
Volume: 279
Issue: 16
Pages: 2917-28
•
•
•
•
•
Publication
19245366 | J:184125
First Author: Webb JD
Year: 2009
Journal: Biochem J
Title: MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
Volume: 420
Issue: 2
Pages: 327-33
•
•
•
•
•
Publication
10952727 | J:64229
First Author: Susin SA
Year: 2000
Journal: J Exp Med
Title: Two distinct pathways leading to nuclear apoptosis.
Volume: 192
Issue: 4
Pages: 571-80
•
•
•
•
•
Publication
11574671 | J:72114
First Author: Meiss G
Year: 2001
Journal: Nucleic Acids Res
Title: Identification of functionally relevant histidine residues in the apoptotic nuclease CAD.
Volume: 29
Issue: 19
Pages: 3901-9
•
•
•
•
•




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